The Biostatistics and Bioinformatics Facility is a shared, institutional resource for biostatistics and bioinformatics consulting and collaboration. We provide rigorous biostatistics and bioinformatics design, analysis and interpretation of experiments and studies, and also create new biostatistics and bioinformatics methods for specific research problems. Our members are broadly skilled in quantitative and computational methods for clinical trials, pre-clinical studies, biological experiments, translational investigations, and cancer prevention and control problems. We embrace new problems and technologies that surface in a rapidly changing scientific environment.

Available software includes:

• Standard statistical packages, such as SAS, Stata, StatXact and R
• Sample size and power computation applications, including PASS, Solo Power Analysis and custom-written applications
• Tools for methodological research, such as Mathematica, Matlab, Fortran, C++
• Bioinformatics tools, including GeneGO (MetaCore), Ingenuity Pathway Analysis suite (IPA), GeneSpring, TRANSFAC professional edition and GCG
• A number of public-domain tools for analyzing transcriptome, genome and proteomics data (such as Bioconductor)
• Other tools including dChip, JavaTreeView, GenMAPP2, GSEA, DNA analytics, MAT, SAMtools, Graphviz, Osprey, Pajek, Cytoscape, Emboss, BWA and BLAT