Publications

Basu J, Reis BS, Peri S, Zha J, Hua X, Ge L, Ferchen K, Nicolas E, Czyzewicz P, Cai KQ, Tan Y, Fuxman Bass JI, Walhout AJM, Grimes HL, Grivennikov SI, Mucida D, Kappes DJ. Essential role of a ThPOK autoregulatory loop in the maintenance of mature CD4+ T cell identity and function. 2021 Nat Immunol. 22:969-982. PMCID: PMC8887595.

Basu J, Zha J, Nicolas E, Coulton M, Czyzewicz P, Hua X, Ge L, Kappes DJ. An autonomous TCR signal-sensing switch influences CD4/CD8 lineage choice in mice. 2022 Commun Biol. 5:84. PMCID: PMC8783009.

Chow HY, Dong B, Valencia CA, Zeng CT, Koch JN, Prudnikova TY, Chernoff J. Group I Paks are essential for epithelial-mesenchymal transition in an Apc-driven model of colorectal cancer.  2018 Nature Communications 9:3473. PMCID: PMC6110733

Fahl, S.P., Coffey, F., Kain, L., Zarin, P., Teyton, L., Zúñiga-Pflücker, J.C., Kappes, D.J., and Wiest, D.L. Role of a selecting ligand in shaping the gamma delta TCR repertoire. 2018.  Proc Natl Acad Sci U S A.  115:1889-1894. PMC5828614

Gabbasov R, Xiao F, Howe CG, Bickel LE, O'Brien SW, Benrubi D, Do TV, Zhou Y, Nicolas E, Cai KQ, Litwin S, Seo S, Golemis EA, Connolly DC. NEDD9 promotes oncogenic signaling, a stem/mesenchymal gene signature, and aggressive ovarian cancer growth in mice. 2018  Oncogene. 37:4854-4870. PMCID: PMC6119087.

Hayakawa, K., Formica, A.M., Zhou, Y., Ichikawa, D., Asano, M., Li, Y.S., Shinton, S.A., Brill-Dashoff, J., Nunez, G., Hardy, R.R.  NLR Nod1 signaling promotes survival of BCR-engaged mature B cells through up-regulated Nod1 as a positive outcome. 2017.  J. Exp. Med.  214:3067-83, PMCID: PMC5626402.

Karakashev S, Fukumoto T, Zhao B, Lin J, Wu S, Fatkhutdinov N, Park PH, Semenova G, Jean S, Cadungog MG, Borowsky ME, Kossenkov AV, Liu Q, Zhang R. EZH2 Inhibition Sensitizes CARM1-High, Homologous Recombination Proficient Ovarian Cancers to PARP Inhibition. 2020 Cancer Cell. 37:157-167, PMCID: PMC7155421.

Kukuyan, A.M., Sementino, E., Kadariya, Y., Menges, C.W., Cheung, M., Tan, Y., Cai, K.Q., Slifker, M.J., Peri, S., Klein-Szanto, A.J., Rauscher, F.J. 3rd, Testa, J.R.  Inactivation of Bap1 cooperates with losses of Nf2 and Cdkn2a to drive the development of pleural malignant mesothelioma in conditional mouse models. 2019. Cancer Res. 79:4113-4123, PMCID: PMC6697648.

Lee HO, He X, Mookerjee-Basu J, Zhongping D, Hua X, Nicolas E, Sulis ML, Ferrando AA, Testa JR, Kappes DJ. Disregulated expression of the transcription factor ThPOK during T-cell development leads to high incidence of T-cell lymphomas. 2015. Proc Natl Acad Sci U S A. 112:7773-8, PMCID: PMC4485124.

Muench DE, Olsson A, Ferchen K, Pham G, Serafin RA, Chutipongtanate S, Dwivedi P, Song B, Hay S, Chetal K, Trump-Durbin LR, Mookerjee-Basu J, Zhang K, Yu JC, Lutzko C, Myers KC, Nazor KL, Greis KD, Kappes DJ, Way SS, Salomonis N, Grimes HL. Mouse models of neutropenia reveal progenitor-stage-specific defects. 2020 Nature. 582:109-114. PMCID: PMC8041154.

Nacson J, Di Marcantonio D, Wang Y, Bernhardy AJ, Clausen E, Hua X, Cai KQ, Martinez E, Feng W, Callén E, Wu W, Gupta GP, Testa JR, Nussenzweig A, Sykes SM, Johnson N. BRCA1 Mutational Complementation Induces Synthetic Viability. 2020 Molec. Cell. 78:951-959. PMCID: PMC7418109.

Payne KK, Mine JA, Biswas S, Chaurio RA, Perales-Puchalt A, Anadon CM, Costich TL, Harro CM, Walrath J, Ming Q, Tcyganov E, Buras AL, Rigolizzo KE, Mandal G, Lajoie J, Ophir M, Tchou J, Marchion D, Luca VC, Bobrowicz P, McLaughlin B, Eskiocak U, Schmidt M, Cubillos-Ruiz JR, Rodriguez PC, Gabrilovich DI, Conejo-Garcia JR. BTN3A1 governs antitumor responses by coordinating αβ and γδ T cells. 2020 Science. 369:942-949; PMCID: PMC7646930.