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Robert G. Uzzo, MD, MBA, FACS

Robert Uzzo, MD, FACS

Clinical Locations

Primary Location

Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111

Secondary Location

Fox Chase Cancer Center Huntingdon Pike
8 Huntingdon Pike
Rockledge, PA 19046

About

Chairman, Department of Surgery

G. Willing "Wing" Pepper Chair in Cancer Research

Professor, Department of Surgery

Professor of Surgery, Temple University Health System

Adjunct Professor of Bioengineering, Temple University College of Engineering

Treatment Focus

  • Robotic and laparoscopic urologic oncology
  • Organ preservation (kidney, bladder, testicular and adrenal)
  • Non-surgical management of low risk urinary tumors
  • Complex urological reconstruction

Research Program

Key Awards

Philadelphia Magazine Top Docs 2020      Urology

Treatment Philosophy

I believe in treating patients as I would my own family. I strive to communicate effectively with patients and family members at all levels. Through extensive discussions with my patients, I develop treatment plans that are both effective and acknowledge that quality of life issues are exceptionally important. I emphasize individually tailored treatments to help patients achieve success and limit treatment-related side effects which can affect quality of life.

I am sensitive to the particular issues regarding surgical treatment of genitourinary cancer, especially the physical and emotional effects on patients and their family. By fostering a doctor-patient relationship based on mutual respect and open dialogue, I encourage patients to become empowered managers of their care... Expand

 

Follow on Twitter: @FCUroOnc

View Dr. Uzzo's PracticeUpdate contributions

Chairman, Department of Surgery

Nationally known as a leader in the field of urologic oncology, Dr. Uzzo has made important clinical, scientific and educational contributions to the Department of Surgery.

A fellow of the American College of Surgeons, Uzzo has consistently ranked among Castle Connolly’s and Philadelphia Magazine's "Top Docs" in urology. He is a national principal investigator for a clinical trial by the Eastern Cooperative Oncology Group to evaluate new, targeted therapies for kidney cancers and immunotherapy.  He is the author of more than 350 chapters, articles, books and abstracts on urologic tumors and has presented hundreds of regional, national and international lectures.

In addition to his extensive clinical practice, he oversees research laboratory initiatives studying molecular mechanisms of genitourinary cancers. In 2003, he was promoted from Associate Professor to Professor with tenure in Fox Chase's division of medical science... Expand

Education and Training

Educational Background

  • Fellow, Urologic Oncology, Cleveland Clinic Foundation
  • Fellow, Renal Transplantation and Renovascular Surgery, Cleveland Clinic Foundation
  • Chief Resident, Urology, New York Hospital-Cornell University Medical Center, New York, NY
  • Senior Resident, Urology, Memorial Sloan-Kettering Cancer Center, New York, NY
  • MD, Cornell Medical College, New York, NY, 1991
  • BS/BA, Union College, Schenectady, NY, 1989, Valedictorian

Certifications

  • Diplomate, American Board of Urology

Memberships

  • The American Urological Association
  • Member, American Association of Genitourinary Surgeons, AAGUS
  • Society of Urologic Oncology, Board of Directors
  • Society of Urologic Oncology, Clinical Trials Consortium, President 
  • Society of Urologic Oncology, Clinical Trials Consortium, Renal Program Chairman  
  • Board of Directors, SUO Clinical Trials Consortia, member-at-large  
  • Fox Chase Cancer Center Society of Scholars  
  • Kidney Cancer Association Medical Advisory Board  
  • Fellow American College of Surgeons (F.A.C.S.)  
  • Society of Urologic Oncology  
  • Pennsylvania Medical Society
  • Philadelphia County Medical Society  
  • The MidAtlantic Section of the American Urological Association
  • Eastern Cooperative Oncology Group  
  • Radiation Therapy Oncology Group
  • American College of Surgeons Oncology Group - Vice Chairman, GU Organ Committee   2002-2006 
  • American Society of Transplant Surgeons 
  • Urologic Society of Transplant and Vascular Surgeons
  • Society for Basic Urologic Research  
  • American Association for Cancer Research

Honors & Awards

  • Philadelphia Magazine Top Doctors, 2002-20
  • Best Doctors in America®, 2013-16, 2019-2020, Urology
  • America’s Top Doctors®, 2008-17
  • AUA Residents National Committee Teaching Award
  • Consumer’s Research Council of America –America’s Top Physicians 
Patient Stories

David Hiltgen

Kidney Cancer

David Hiltgen

Kidney Cancer

My kidney cancer was discovered at the worst time: right at the start of the COVID-19 pandemic.

Luciano Orsini

Kidney Cancer

Luciano Orsini

Kidney Cancer

I’m 58 years old and live in Sicklerville, New Jersey. In normal times, summer is my favorite time of year. I’d have been looking forward to it this year, if COVID-19 hadn’t happened and forced me to delay my surgery for kidney cancer.

Felix (Phil) Sanchez

Bladder Cancer

Felix (Phil) Sanchez

Bladder Cancer

I follow up with people and act as a mentor. I let them know they are able to contact me at any time, and I can offer them peace of mind from someone who has been where they are headed.

Charlie Smithgall

Kidney Cancer

Charlie Smithgall

Kidney Cancer

"Although cancer is not the news I was expecting to hear, I’m able to see the silver lining in how things worked out the way they did. "

Fred Cohen

Bladder Cancer

Fred Cohen

Bladder Cancer

"Two dates are seared into my memory. On November 30, 2015, my wife and I were attending a funeral for a very dear friend, who had died after a long ordeal with kidney cancer. After the viewing I used the restroom and I noticed something unusual – blood in my urine. Obviously concerned, I called my urologist in the car on the way to the cemetery. He recommended I come in right away for an exam. On January 7, 2016, after weeks of tests and exams, the suspicion was confirmed: I had bladder cancer."

Pages

Research Profile

Research Program

Research Interests

  • Clinical and translational questions involving renal cell carcinoma including decision making models in the management of renal cancers and processes/quality of care in urologic malignancies
  • Analyses of outcomes involving excision, ablation, and active surveillance for localized kidney cancer and techniques/outcomes of surgery in locally advanced and metastatic RCC
  • Actively develop and accrue to multiple industry sponsored national and international urological oncology trials as well as investigator initiated trials.
  • Translational interests include biomarker development in kidney cancer and the role of zinc dyshomeostasis in prostate cancer
Publications

Selected Publications

Chapters and Publications from over 400:

Campbell S.C., Novick A.C., Belldegrun A., Blute M.L., Chow G.K., Derweesh I.H., Faraday M.M., Kaouk J.H., Leveillee R.J., Matin S.F., Russo P., Uzzo R.G., Guideline for Management of the Clinical T1 Renal Mass, 2009, Journal of Urology, 182, 4 SUPPL., 1271, 1279 PubMed

Goel N, Manstein SM, Ward WH, DeMora L, Smaldone MC, Farma JM, Uzzo RG, Esnaola NF. Does the Surgical Apgar Score predict serious complications after elective major cancer surgery? Journal of Surgical Research, 231:242-7, 2018. 

Uzzo R.G., Novick A.C., Nephron sparing surgery for renal tumors: Indications, techniques and outcomes, 2001, Journal of Urology, 166, 1, 6, 18 PubMed

Kutikov A, Uzzo RG. The RENAL Nephrometry Score: A comprehensive standardized system for quantitating renal tumor size, location and depth. J Urol, 182(3):844-53, 2009. (cited 401 times) PubMed

Chawla S.N., Crispen P.L., Hanlon A.L., Greenberg R.E., Chen D.Y.T., Uzzo R.G., The natural history of observed enhancing renal masses: Meta-analysis and review of the world literature, 2006, Journal of Urology, 175, 2, 425, 431 PubMed

Kunkle D.A., Egleston B.L., Uzzo R.G., Excise, Ablate or Observe: The Small Renal Mass Dilemma-A Meta-Analysis and Review, 2008, Journal of Urology, 179, 4, 1227, 1234 PubMed

Kunkle D.A., Uzzo R.G., Cryoablation or radiofrequency ablation of the small renal mass: A meta-analysis, 2008, Cancer, 113, 10, 2671, 2680 PubMed

Uzzo R.G., Wei J.T., Waldbaum R.S., Perlmutter A.P., Byrne J.C., Vaughan Jr. D., The influence of prostate size on cancer detection, 1995, Urology, 46, 6, 831, 836 PubMed

Pollack A., Hanlon A.L., Horwitz E.M., Feigenberg S.J., Konski A.A., Movsas B., Greenberg R.E., Uzzo R.G., Ma C.-M.C., McNeeley S.W., Buyyounouski M.K., Price Jr. R.A., Dosimetry and preliminary acute toxicity in the first 100 men treated for prostate cancer on a randomized hypofractionation dose escalation trial, 2006, International Journal of Radiation Oncology Biology Physics, 64, 2, 518, 526 PubMed

Qiao J., Uzzo R., Obara-Ishihara T., Degenstein L., Fuchs E., Herzlinger D., FGF-7 modulates ureteric bud growth and nephron number in the developing kidney, 1999, Development, 126, 3, 547, 554

Lane B.R., Russo P., Uzzo R.G., Hernandez A.V., Boorjian S.A., Thompson R.H., Fergany A.F., Love T.E., Campbell S.C., Comparison of cold and warm ischemia during partial nephrectomy in 660 solitary kidneys reveals predominant role of nonmodifiable factors in determining ultimate renal function, 2011, Journal of Urology, 185, 2, 421, 427 PubMed

Mann S.J., Pickering T.G., Sos T.A., Uzzo R.G., Sarkar S., Friend K., Rackson M.E., Laragh J.H., Captopril renography in the diagnosis of renal artery stenosis: accuracy and limitations, 1991, The American Journal of Medicine, 90, 1, 30, 40 PubMed

Dulaimi E., Uzzo R.G., Greenberg R.E., Al-Saleem T., Cairns P., Detection of Bladder Cancer in Urine by a Tumor Suppressor Gene Hypermethylation Panel, 2004, Clinical Cancer Research, 10, 6, 1887, 1893 PubMed

Kunkle D.A., Crispen P.L., Chen D.Y.T., Greenberg R.E., Uzzo R.G., Enhancing Renal Masses With Zero Net Growth During Active Surveillance, 2007, Journal of Urology, 177, 3, 849, 854 PubMed

Touijer K., Jacqmin D., Kavoussi L.R., Montorsi F., Patard J.J., Rogers C.G., Russo P., Uzzo R.G., Van Poppel H., The Expanding Role of Partial Nephrectomy: A Critical Analysis of Indications, Results, and Complications, 2010, European Urology, 57, 2, 214, 222 PubMed

Additional Publications

My NCBI

Ratings

386 PATIENT SATISFACTION REVIEWS

Our Patient Satisfaction Rating is an average of all responses to care provider related questions from our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more.

OVERALL RATING

5.0 / 5.0

RATINGS BREAKDOWN

  • 5.0
  • 5.0
  • 5.0
  • 5.0
  • 4.9

98 PATIENT COMMENTS

  • 5.0
    January 30, 2021
    Doctor Uzzo is amazing I don't think I'd be alive if it weren't for him I'm grateful for his work ethic an pride he takes in his craft because I've seen doctors just tell you things to get you out of there but Doctor Uzzo treats every patient like as if they were his own family members I was very lucky
  • 5.0
    January 29, 2021
    I was treated as expected. Each time I had an appointment I was treated with respect,
  • 4.5
    January 26, 2021
    Have seen Dr. Uzzo many times as a surgical inpatient and outpatient. Am completely satisfied with the care provided by him and his team.
  • 5.0
    January 26, 2021
    [...] overall a pleasant & comfortable experience.
  • No Star Ratings Available January 25, 2021
    Dr. Uzzo is very knowledgeable and was able to explain what my options are for prostrate cancer
  • No Star Ratings Available January 24, 2021
    Dr. Uzzo is an amazing doctor and an amazing, caring individual.
  • 5.0
    January 22, 2021
    i couldn't get any better care than being Dr.Uzzu patient I new I was in good hands the day we met and after talking to him he made me feel completely confident about the surgery he was going to perform on me he is a great surgeon and a wonderful person
  • 5.0
    January 15, 2021
    Really went to extreme to help with my needs.
  • 5.0
    January 09, 2021
    I love the doctor and his staff
  • 5.0
    January 09, 2021
    My father's personal friend and trusted urologist highly recommended Dr. Uzzo. I went to Dr. Uzzo for a second opinion. My wife and I were not disappointed. Exceptional care from Dr. Uzzo and the staff. Much more thorough and informative. Dr. Uzzo related the information in a way that was readily understandable. The staff was courteous and professional. They went out of there way for me. Thank you.
  • No Star Ratings Available December 23, 2020
    Extremely pleased with the session
  • 5.0
    December 22, 2020
    Dr. Uzzo is an excellent physician. He is the BEST!!!
  • 5.0
    December 09, 2020
    good
  • 5.0
    December 09, 2020
    Dr. Uzzo has always been so amazing!
  • 5.0
    December 02, 2020
    I am very satisfied with care provided to me.
  • 5.0
    December 01, 2020
    Always helpful, friendly.
  • No Star Ratings Available November 29, 2020
    Dr. Uzzo made sure that I understood the implications of his conclusions and plans, with careful consideration of my being a physician with an understanding of genitourinary oncology.
  • 5.0
    November 21, 2020
    Excellent doctor and nursing staff as well as intake and reception people. All excellent!
  • No Star Ratings Available November 06, 2020
    Never, ever had a Physician explain situation as well as Dr. Uzzo.
  • No Star Ratings Available October 30, 2020
    Despite being anxious over this situation, I am trying to do what is necessary to have the best result. The nurse navigator was on top of her game for setting this up. I felt Dr. Uzzo asked the right questions to help him understand what he needed to know to result in the best outcome. [...]
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