Robert Uzzo, MD, MBA, FACS

- Request Appointment
- Clinical Locations
- About
- Education and Training
- Patient Stories
- Research Profile
- Publications
- Ratings
Clinical Locations
Primary Location
Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111
Secondary Location
Huntingdon Pike
8 Huntingdon Pike
Rockledge, PA
Interim CEO, Hospital of Fox Chase Cancer Center
Chairman, Department of Surgery
G. Willing "Wing" Pepper Chair in Cancer Research
Professor, Department of Surgery
Professor of Surgery, Temple University Health System
Adjunct Professor of Bioengineering, Temple University College of Engineering
Specialties
Treatment Focus
- Robotic and laparoscopic urologic oncology
- Organ preservation (kidney, bladder, testicular and adrenal)
- Non-surgical management of low risk urinary tumors
- Complex urological reconstruction
Research Program
Key Awards
![]() |
Urology |
Treatment Philosophy
Educational Background
- Fellow, Urologic Oncology, Cleveland Clinic Foundation
- Fellow, Renal Transplantation and Renovascular Surgery, Cleveland Clinic Foundation
- Chief Resident, Urology, New York Hospital-Cornell University Medical Center, New York, NY
- Senior Resident, Urology, Memorial Sloan-Kettering Cancer Center, New York, NY
- MD, Cornell Medical College, New York, NY, 1991
- BS/BA, Union College, Schenectady, NY, 1987, Valedictorian
Certifications
- Diplomate, American Board of Urology
Memberships
- The American Urological Association
- Member, American Association of Genitourinary Surgeons, AAGUS
- Society of Urologic Oncology, Board of Directors
- Society of Urologic Oncology, Clinical Trials Consortium, President
- Society of Urologic Oncology, Clinical Trials Consortium, Renal Program Chairman
- Board of Directors, SUO Clinical Trials Consortia, member-at-large
- Fox Chase Cancer Center Society of Scholars
- Kidney Cancer Association Medical Advisory Board
- Fellow American College of Surgeons (F.A.C.S.)
- Society of Urologic Oncology
- Pennsylvania Medical Society
- Philadelphia County Medical Society
- The MidAtlantic Section of the American Urological Association
- Eastern Cooperative Oncology Group
- Radiation Therapy Oncology Group
- American College of Surgeons Oncology Group - Vice Chairman, GU Organ Committee 2002-2006
- American Society of Transplant Surgeons
- Urologic Society of Transplant and Vascular Surgeons
- Society for Basic Urologic Research
- American Association for Cancer Research
Honors & Awards
- Philadelphia Magazine Top Doctors, 2002-20
- Best Doctors in America®, 2013-16, 2019-2020, Urology
- America’s Top Doctors®, 2008-17
- AUA Residents National Committee Teaching Award
- Consumer’s Research Council of America –America’s Top Physicians
Research Program
Research Interests
- Clinical and translational questions involving renal cell carcinoma including decision making models in the management of renal cancers and processes/quality of care in urologic malignancies
- Analyses of outcomes involving excision, ablation, and active surveillance for localized kidney cancer and techniques/outcomes of surgery in locally advanced and metastatic RCC
- Actively develop and accrue to multiple industry sponsored national and international urological oncology trials as well as investigator initiated trials.
- Translational interests include biomarker development in kidney cancer and the role of zinc dyshomeostasis in prostate cancer
Selected Publications
Chapters and Publications from over 400:
Campbell S.C., Novick A.C., Belldegrun A., Blute M.L., Chow G.K., Derweesh I.H., Faraday M.M., Kaouk J.H., Leveillee R.J., Matin S.F., Russo P., Uzzo R.G., Guideline for Management of the Clinical T1 Renal Mass, 2009, Journal of Urology, 182, 4 SUPPL., 1271, 1279 PubMed
Goel N, Manstein SM, Ward WH, DeMora L, Smaldone MC, Farma JM, Uzzo RG, Esnaola NF. Does the Surgical Apgar Score predict serious complications after elective major cancer surgery? Journal of Surgical Research, 231:242-7, 2018.
Uzzo R.G., Novick A.C., Nephron sparing surgery for renal tumors: Indications, techniques and outcomes, 2001, Journal of Urology, 166, 1, 6, 18 PubMed
Kutikov A, Uzzo RG. The RENAL Nephrometry Score: A comprehensive standardized system for quantitating renal tumor size, location and depth. J Urol, 182(3):844-53, 2009. (cited 401 times) PubMed
Chawla S.N., Crispen P.L., Hanlon A.L., Greenberg R.E., Chen D.Y.T., Uzzo R.G., The natural history of observed enhancing renal masses: Meta-analysis and review of the world literature, 2006, Journal of Urology, 175, 2, 425, 431 PubMed
Kunkle D.A., Egleston B.L., Uzzo R.G., Excise, Ablate or Observe: The Small Renal Mass Dilemma-A Meta-Analysis and Review, 2008, Journal of Urology, 179, 4, 1227, 1234 PubMed
Kunkle D.A., Uzzo R.G., Cryoablation or radiofrequency ablation of the small renal mass: A meta-analysis, 2008, Cancer, 113, 10, 2671, 2680 PubMed
Uzzo R.G., Wei J.T., Waldbaum R.S., Perlmutter A.P., Byrne J.C., Vaughan Jr. D., The influence of prostate size on cancer detection, 1995, Urology, 46, 6, 831, 836 PubMed
Pollack A., Hanlon A.L., Horwitz E.M., Feigenberg S.J., Konski A.A., Movsas B., Greenberg R.E., Uzzo R.G., Ma C.-M.C., McNeeley S.W., Buyyounouski M.K., Price Jr. R.A., Dosimetry and preliminary acute toxicity in the first 100 men treated for prostate cancer on a randomized hypofractionation dose escalation trial, 2006, International Journal of Radiation Oncology Biology Physics, 64, 2, 518, 526 PubMed
Qiao J., Uzzo R., Obara-Ishihara T., Degenstein L., Fuchs E., Herzlinger D., FGF-7 modulates ureteric bud growth and nephron number in the developing kidney, 1999, Development, 126, 3, 547, 554
Lane B.R., Russo P., Uzzo R.G., Hernandez A.V., Boorjian S.A., Thompson R.H., Fergany A.F., Love T.E., Campbell S.C., Comparison of cold and warm ischemia during partial nephrectomy in 660 solitary kidneys reveals predominant role of nonmodifiable factors in determining ultimate renal function, 2011, Journal of Urology, 185, 2, 421, 427 PubMed
Mann S.J., Pickering T.G., Sos T.A., Uzzo R.G., Sarkar S., Friend K., Rackson M.E., Laragh J.H., Captopril renography in the diagnosis of renal artery stenosis: accuracy and limitations, 1991, The American Journal of Medicine, 90, 1, 30, 40 PubMed
Dulaimi E., Uzzo R.G., Greenberg R.E., Al-Saleem T., Cairns P., Detection of Bladder Cancer in Urine by a Tumor Suppressor Gene Hypermethylation Panel, 2004, Clinical Cancer Research, 10, 6, 1887, 1893 PubMed
Kunkle D.A., Crispen P.L., Chen D.Y.T., Greenberg R.E., Uzzo R.G., Enhancing Renal Masses With Zero Net Growth During Active Surveillance, 2007, Journal of Urology, 177, 3, 849, 854 PubMed
Touijer K., Jacqmin D., Kavoussi L.R., Montorsi F., Patard J.J., Rogers C.G., Russo P., Uzzo R.G., Van Poppel H., The Expanding Role of Partial Nephrectomy: A Critical Analysis of Indications, Results, and Complications, 2010, European Urology, 57, 2, 214, 222 PubMed
Additional Publications
Contact Information
Follow on Twitter: @FCUroOnc

Clinical Locations
Primary Location
Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111
Secondary Location
Huntingdon Pike
8 Huntingdon Pike
Rockledge, PA
Contact Information
Follow on Twitter: @FCUroOnc
Interim CEO, Hospital of Fox Chase Cancer Center
Chairman, Department of Surgery
G. Willing "Wing" Pepper Chair in Cancer Research
Professor, Department of Surgery
Professor of Surgery, Temple University Health System
Adjunct Professor of Bioengineering, Temple University College of Engineering
Treatment Focus
- Robotic and laparoscopic urologic oncology
- Organ preservation (kidney, bladder, testicular and adrenal)
- Non-surgical management of low risk urinary tumors
- Complex urological reconstruction
Research Program
Key Awards
![]() |
Urology |
Treatment Philosophy
Education
Educational Background
- Fellow, Urologic Oncology, Cleveland Clinic Foundation
- Fellow, Renal Transplantation and Renovascular Surgery, Cleveland Clinic Foundation
- Chief Resident, Urology, New York Hospital-Cornell University Medical Center, New York, NY
- Senior Resident, Urology, Memorial Sloan-Kettering Cancer Center, New York, NY
- MD, Cornell Medical College, New York, NY, 1991
- BS/BA, Union College, Schenectady, NY, 1987, Valedictorian
Certifications
- Diplomate, American Board of Urology
Memberships
- The American Urological Association
- Member, American Association of Genitourinary Surgeons, AAGUS
- Society of Urologic Oncology, Board of Directors
- Society of Urologic Oncology, Clinical Trials Consortium, President
- Society of Urologic Oncology, Clinical Trials Consortium, Renal Program Chairman
- Board of Directors, SUO Clinical Trials Consortia, member-at-large
- Fox Chase Cancer Center Society of Scholars
- Kidney Cancer Association Medical Advisory Board
- Fellow American College of Surgeons (F.A.C.S.)
- Society of Urologic Oncology
- Pennsylvania Medical Society
- Philadelphia County Medical Society
- The MidAtlantic Section of the American Urological Association
- Eastern Cooperative Oncology Group
- Radiation Therapy Oncology Group
- American College of Surgeons Oncology Group - Vice Chairman, GU Organ Committee 2002-2006
- American Society of Transplant Surgeons
- Urologic Society of Transplant and Vascular Surgeons
- Society for Basic Urologic Research
- American Association for Cancer Research
Honors & Awards
- Philadelphia Magazine Top Doctors, 2002-20
- Best Doctors in America®, 2013-16, 2019-2020, Urology
- America’s Top Doctors®, 2008-17
- AUA Residents National Committee Teaching Award
- Consumer’s Research Council of America –America’s Top Physicians
Research Profile
Research Interests
- Clinical and translational questions involving renal cell carcinoma including decision making models in the management of renal cancers and processes/quality of care in urologic malignancies
- Analyses of outcomes involving excision, ablation, and active surveillance for localized kidney cancer and techniques/outcomes of surgery in locally advanced and metastatic RCC
- Actively develop and accrue to multiple industry sponsored national and international urological oncology trials as well as investigator initiated trials.
- Translational interests include biomarker development in kidney cancer and the role of zinc dyshomeostasis in prostate cancer
Publications
Selected Publications
Chapters and Publications from over 400:
Campbell S.C., Novick A.C., Belldegrun A., Blute M.L., Chow G.K., Derweesh I.H., Faraday M.M., Kaouk J.H., Leveillee R.J., Matin S.F., Russo P., Uzzo R.G., Guideline for Management of the Clinical T1 Renal Mass, 2009, Journal of Urology, 182, 4 SUPPL., 1271, 1279 PubMed
Goel N, Manstein SM, Ward WH, DeMora L, Smaldone MC, Farma JM, Uzzo RG, Esnaola NF. Does the Surgical Apgar Score predict serious complications after elective major cancer surgery? Journal of Surgical Research, 231:242-7, 2018.
Uzzo R.G., Novick A.C., Nephron sparing surgery for renal tumors: Indications, techniques and outcomes, 2001, Journal of Urology, 166, 1, 6, 18 PubMed
Kutikov A, Uzzo RG. The RENAL Nephrometry Score: A comprehensive standardized system for quantitating renal tumor size, location and depth. J Urol, 182(3):844-53, 2009. (cited 401 times) PubMed
Chawla S.N., Crispen P.L., Hanlon A.L., Greenberg R.E., Chen D.Y.T., Uzzo R.G., The natural history of observed enhancing renal masses: Meta-analysis and review of the world literature, 2006, Journal of Urology, 175, 2, 425, 431 PubMed
Kunkle D.A., Egleston B.L., Uzzo R.G., Excise, Ablate or Observe: The Small Renal Mass Dilemma-A Meta-Analysis and Review, 2008, Journal of Urology, 179, 4, 1227, 1234 PubMed
Kunkle D.A., Uzzo R.G., Cryoablation or radiofrequency ablation of the small renal mass: A meta-analysis, 2008, Cancer, 113, 10, 2671, 2680 PubMed
Uzzo R.G., Wei J.T., Waldbaum R.S., Perlmutter A.P., Byrne J.C., Vaughan Jr. D., The influence of prostate size on cancer detection, 1995, Urology, 46, 6, 831, 836 PubMed
Pollack A., Hanlon A.L., Horwitz E.M., Feigenberg S.J., Konski A.A., Movsas B., Greenberg R.E., Uzzo R.G., Ma C.-M.C., McNeeley S.W., Buyyounouski M.K., Price Jr. R.A., Dosimetry and preliminary acute toxicity in the first 100 men treated for prostate cancer on a randomized hypofractionation dose escalation trial, 2006, International Journal of Radiation Oncology Biology Physics, 64, 2, 518, 526 PubMed
Qiao J., Uzzo R., Obara-Ishihara T., Degenstein L., Fuchs E., Herzlinger D., FGF-7 modulates ureteric bud growth and nephron number in the developing kidney, 1999, Development, 126, 3, 547, 554
Lane B.R., Russo P., Uzzo R.G., Hernandez A.V., Boorjian S.A., Thompson R.H., Fergany A.F., Love T.E., Campbell S.C., Comparison of cold and warm ischemia during partial nephrectomy in 660 solitary kidneys reveals predominant role of nonmodifiable factors in determining ultimate renal function, 2011, Journal of Urology, 185, 2, 421, 427 PubMed
Mann S.J., Pickering T.G., Sos T.A., Uzzo R.G., Sarkar S., Friend K., Rackson M.E., Laragh J.H., Captopril renography in the diagnosis of renal artery stenosis: accuracy and limitations, 1991, The American Journal of Medicine, 90, 1, 30, 40 PubMed
Dulaimi E., Uzzo R.G., Greenberg R.E., Al-Saleem T., Cairns P., Detection of Bladder Cancer in Urine by a Tumor Suppressor Gene Hypermethylation Panel, 2004, Clinical Cancer Research, 10, 6, 1887, 1893 PubMed
Kunkle D.A., Crispen P.L., Chen D.Y.T., Greenberg R.E., Uzzo R.G., Enhancing Renal Masses With Zero Net Growth During Active Surveillance, 2007, Journal of Urology, 177, 3, 849, 854 PubMed
Touijer K., Jacqmin D., Kavoussi L.R., Montorsi F., Patard J.J., Rogers C.G., Russo P., Uzzo R.G., Van Poppel H., The Expanding Role of Partial Nephrectomy: A Critical Analysis of Indications, Results, and Complications, 2010, European Urology, 57, 2, 214, 222 PubMed
80 PATIENT COMMENTS