Robert G. Uzzo, MD, MBA, FACS
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Clinical Locations
Primary Location
Huntingdon Pike
8 Huntingdon Pike
Rockledge, PA
Secondary Location
Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111
Chair, Department of Surgical Oncology
G. Willing "Wing" Pepper Chair in Cancer Research
Kidney, Bladder, and Prostate Cancer TRDG Member
Senior Vice-President, Physician Services
President, FCCC Medical Group, Inc.
Professor of Surgery, Temple University Health System
Specialties
Treatment Focus
- Robotic and laparoscopic urologic oncology
- Organ preservation (kidney, bladder, testicular and adrenal)
- Non-surgical management of low risk urinary tumors
- Complex urological reconstruction
Research Program
Key Awards
UrologyTreatment Philosophy
Educational Background
- Fellow, Urologic Oncology, Cleveland Clinic Foundation
- Fellow, Renal Transplantation and Renovascular Surgery, Cleveland Clinic Foundation
- Chief Resident, Urology, New York Hospital-Cornell University Medical Center, New York, NY
- Senior Resident, Urology, Memorial Sloan-Kettering Cancer Center, New York, NY
- MD, Cornell Medical College, New York, NY, 1991
- BS/BA, Union College, Schenectady, NY, 1989, Valedictorian
Certifications
- Diplomate, American Board of Urology
Memberships
- The American Urological Association
- Member, American Association of Genitourinary Surgeons, AAGUS
- Society of Urologic Oncology, Board of Directors
- Society of Urologic Oncology, Clinical Trials Consortium, President
- Society of Urologic Oncology, Clinical Trials Consortium, Renal Program Chairman
- Board of Directors, SUO Clinical Trials Consortia, member-at-large
- Fox Chase Cancer Center Society of Scholars
- Kidney Cancer Association Medical Advisory Board
- Fellow American College of Surgeons (F.A.C.S.)
- Society of Urologic Oncology
- Pennsylvania Medical Society
- Philadelphia County Medical Society
- The MidAtlantic Section of the American Urological Association
- Eastern Cooperative Oncology Group
- Radiation Therapy Oncology Group
- American College of Surgeons Oncology Group - Vice Chairman, GU Organ Committee 2002-2006
- American Society of Transplant Surgeons
- Urologic Society of Transplant and Vascular Surgeons
- Society for Basic Urologic Research
- American Association for Cancer Research
Honors & Awards
- Philadelphia Magazine Top Doctors, 2002-19
- America’s Top Doctors®, 2008-17
- Best Doctors in America®, 2013-16
- AUA Residents National Committee Teaching Award
- Consumer’s Research Council of America –America’s Top Physicians
Charlie Smithgall
Charlie Smithgall
I love Lancaster, Pennsylvania. I’m 73 and I’ve lived in Lancaster my whole life. My family’s been a part of this town for more than 100 years. I own my family’s drugstore business that was started when my father opened a pharmacy in his mother’s living room in 1916. I even served as Mayor of Lancaster from 1998 to 2006, and I love my community. For the most part, things are peaceful. But in 2018, I almost lost everything.
Fred Cohen
Fred Cohen
"Two dates are seared into my memory. On November 30, 2015, my wife and I were attending a funeral for a very dear friend, who had died after a long ordeal with kidney cancer. After the viewing I used the restroom and I noticed something unusual – blood in my urine. Obviously concerned, I called my urologist in the car on the way to the cemetery. He recommended I come in right away for an exam. On January 7, 2016, after weeks of tests and exams, the suspicion was confirmed: I had bladder cancer."
John Roley
John Roley
In the fall of 2007, John Roley was shocked to learn he had kidney cancer after experiencing severe stomach pain. After meeting with his doctor, he decided to get a second opinion from Dr. Robert Uzzo, chief of surgical oncology at Fox Chase Cancer Center. Rather than traditional surgery, Dr. Uzzo recommended two surgeries using the minimally-invasive da Vinci robotic surgical procedure that makes tiny incisions, results in very little scarring, and produces almost no bleeding. After the surgeries, John had no complications, healed quickly, and returned to work within weeks. "The doctors and nurses at Fox Chase were simply great in taking care of me and helping me to recover so quickly," he said. "I am forever grateful to everyone who found the problem, fixed the problem, and restored me to excellent health, and I pray that they are able to help others the way they helped me."
Denise Coldwater
Denise Coldwater
Based on my history with cancer, I often feel like the luckiest person on earth. In 1999, at the age of 45, I was diagnosed with kidney cancer. At the time, my only choice was a total nephrectomy (removal of the kidney).
Mike Phillips
Mike Phillips
When Mike Phillips was diagnosed with kidney cancer, he sought treatment at Fox Chase Cancer Center, where he underwent a partial nephrectomy. Unfortunately, the cancer returned six years later, in 2011, and this time both kidneys were affected. During this time, Mike was also having other health complications, including prostate cancer and a left hemispheric stroke that had no residual effects. In 2015, he received a kidney transplant and has been doing well since. "Now, fully recovered, I continue to do part-time business consulting, given my 45 years of business experience, 30 years in the world of franchising, and 15 in senior care/housing," Mike said, adding, "I hope to start volunteering soon at Fox Chase to provide phone counseling for patients who are dealing with cancer. My advice to others is to be the boss; it is your body, and you must be the captain of your ship."
Pages
Research Program
Research Interests
- Clinical and translational questions involving renal cell carcinoma including decision making models in the management of renal cancers and processes/quality of care in urologic malignancies
- Analyses of outcomes involving excision, ablation, and active surveillance for localized kidney cancer and techniques/outcomes of surgery in locally advanced and metastatic RCC
- Actively develop and accrue to multiple industry sponsored national and international urological oncology trials as well as investigator initiated trials.
- Translational interests include biomarker development in kidney cancer and the role of zinc dyshomeostasis in prostate cancer
Selected Publications
Chapters and Publications from over 400:
Campbell S.C., Novick A.C., Belldegrun A., Blute M.L., Chow G.K., Derweesh I.H., Faraday M.M., Kaouk J.H., Leveillee R.J., Matin S.F., Russo P., Uzzo R.G., Guideline for Management of the Clinical T1 Renal Mass, 2009, Journal of Urology, 182, 4 SUPPL., 1271, 1279 PubMed
Goel N, Manstein SM, Ward WH, DeMora L, Smaldone MC, Farma JM, Uzzo RG, Esnaola NF. Does the Surgical Apgar Score predict serious complications after elective major cancer surgery? Journal of Surgical Research, 231:242-7, 2018.
Uzzo R.G., Novick A.C., Nephron sparing surgery for renal tumors: Indications, techniques and outcomes, 2001, Journal of Urology, 166, 1, 6, 18 PubMed
Kutikov A, Uzzo RG. The RENAL Nephrometry Score: A comprehensive standardized system for quantitating renal tumor size, location and depth. J Urol, 182(3):844-53, 2009. (cited 401 times) PubMed
Chawla S.N., Crispen P.L., Hanlon A.L., Greenberg R.E., Chen D.Y.T., Uzzo R.G., The natural history of observed enhancing renal masses: Meta-analysis and review of the world literature, 2006, Journal of Urology, 175, 2, 425, 431 PubMed
Kunkle D.A., Egleston B.L., Uzzo R.G., Excise, Ablate or Observe: The Small Renal Mass Dilemma-A Meta-Analysis and Review, 2008, Journal of Urology, 179, 4, 1227, 1234 PubMed
Kunkle D.A., Uzzo R.G., Cryoablation or radiofrequency ablation of the small renal mass: A meta-analysis, 2008, Cancer, 113, 10, 2671, 2680 PubMed
Uzzo R.G., Wei J.T., Waldbaum R.S., Perlmutter A.P., Byrne J.C., Vaughan Jr. D., The influence of prostate size on cancer detection, 1995, Urology, 46, 6, 831, 836 PubMed
Pollack A., Hanlon A.L., Horwitz E.M., Feigenberg S.J., Konski A.A., Movsas B., Greenberg R.E., Uzzo R.G., Ma C.-M.C., McNeeley S.W., Buyyounouski M.K., Price Jr. R.A., Dosimetry and preliminary acute toxicity in the first 100 men treated for prostate cancer on a randomized hypofractionation dose escalation trial, 2006, International Journal of Radiation Oncology Biology Physics, 64, 2, 518, 526 PubMed
Qiao J., Uzzo R., Obara-Ishihara T., Degenstein L., Fuchs E., Herzlinger D., FGF-7 modulates ureteric bud growth and nephron number in the developing kidney, 1999, Development, 126, 3, 547, 554
Lane B.R., Russo P., Uzzo R.G., Hernandez A.V., Boorjian S.A., Thompson R.H., Fergany A.F., Love T.E., Campbell S.C., Comparison of cold and warm ischemia during partial nephrectomy in 660 solitary kidneys reveals predominant role of nonmodifiable factors in determining ultimate renal function, 2011, Journal of Urology, 185, 2, 421, 427 PubMed
Mann S.J., Pickering T.G., Sos T.A., Uzzo R.G., Sarkar S., Friend K., Rackson M.E., Laragh J.H., Captopril renography in the diagnosis of renal artery stenosis: accuracy and limitations, 1991, The American Journal of Medicine, 90, 1, 30, 40 PubMed
Dulaimi E., Uzzo R.G., Greenberg R.E., Al-Saleem T., Cairns P., Detection of Bladder Cancer in Urine by a Tumor Suppressor Gene Hypermethylation Panel, 2004, Clinical Cancer Research, 10, 6, 1887, 1893 PubMed
Kunkle D.A., Crispen P.L., Chen D.Y.T., Greenberg R.E., Uzzo R.G., Enhancing Renal Masses With Zero Net Growth During Active Surveillance, 2007, Journal of Urology, 177, 3, 849, 854 PubMed
Touijer K., Jacqmin D., Kavoussi L.R., Montorsi F., Patard J.J., Rogers C.G., Russo P., Uzzo R.G., Van Poppel H., The Expanding Role of Partial Nephrectomy: A Critical Analysis of Indications, Results, and Complications, 2010, European Urology, 57, 2, 214, 222 PubMed
Additional Publications
Clinical Locations
Primary Location
Huntingdon Pike
8 Huntingdon Pike
Rockledge, PA
Secondary Location
Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111
Chair, Department of Surgical Oncology
G. Willing "Wing" Pepper Chair in Cancer Research
Kidney, Bladder, and Prostate Cancer TRDG Member
Senior Vice-President, Physician Services
President, FCCC Medical Group, Inc.
Professor of Surgery, Temple University Health System
Treatment Focus
- Robotic and laparoscopic urologic oncology
- Organ preservation (kidney, bladder, testicular and adrenal)
- Non-surgical management of low risk urinary tumors
- Complex urological reconstruction
Research Program
Key Awards
UrologyTreatment Philosophy
Education
Educational Background
- Fellow, Urologic Oncology, Cleveland Clinic Foundation
- Fellow, Renal Transplantation and Renovascular Surgery, Cleveland Clinic Foundation
- Chief Resident, Urology, New York Hospital-Cornell University Medical Center, New York, NY
- Senior Resident, Urology, Memorial Sloan-Kettering Cancer Center, New York, NY
- MD, Cornell Medical College, New York, NY, 1991
- BS/BA, Union College, Schenectady, NY, 1989, Valedictorian
Certifications
- Diplomate, American Board of Urology
Memberships
- The American Urological Association
- Member, American Association of Genitourinary Surgeons, AAGUS
- Society of Urologic Oncology, Board of Directors
- Society of Urologic Oncology, Clinical Trials Consortium, President
- Society of Urologic Oncology, Clinical Trials Consortium, Renal Program Chairman
- Board of Directors, SUO Clinical Trials Consortia, member-at-large
- Fox Chase Cancer Center Society of Scholars
- Kidney Cancer Association Medical Advisory Board
- Fellow American College of Surgeons (F.A.C.S.)
- Society of Urologic Oncology
- Pennsylvania Medical Society
- Philadelphia County Medical Society
- The MidAtlantic Section of the American Urological Association
- Eastern Cooperative Oncology Group
- Radiation Therapy Oncology Group
- American College of Surgeons Oncology Group - Vice Chairman, GU Organ Committee 2002-2006
- American Society of Transplant Surgeons
- Urologic Society of Transplant and Vascular Surgeons
- Society for Basic Urologic Research
- American Association for Cancer Research
Honors & Awards
- Philadelphia Magazine Top Doctors, 2002-19
- America’s Top Doctors®, 2008-17
- Best Doctors in America®, 2013-16
- AUA Residents National Committee Teaching Award
- Consumer’s Research Council of America –America’s Top Physicians
Research Profile
Research Interests
- Clinical and translational questions involving renal cell carcinoma including decision making models in the management of renal cancers and processes/quality of care in urologic malignancies
- Analyses of outcomes involving excision, ablation, and active surveillance for localized kidney cancer and techniques/outcomes of surgery in locally advanced and metastatic RCC
- Actively develop and accrue to multiple industry sponsored national and international urological oncology trials as well as investigator initiated trials.
- Translational interests include biomarker development in kidney cancer and the role of zinc dyshomeostasis in prostate cancer
Publications
Selected Publications
Chapters and Publications from over 400:
Campbell S.C., Novick A.C., Belldegrun A., Blute M.L., Chow G.K., Derweesh I.H., Faraday M.M., Kaouk J.H., Leveillee R.J., Matin S.F., Russo P., Uzzo R.G., Guideline for Management of the Clinical T1 Renal Mass, 2009, Journal of Urology, 182, 4 SUPPL., 1271, 1279 PubMed
Goel N, Manstein SM, Ward WH, DeMora L, Smaldone MC, Farma JM, Uzzo RG, Esnaola NF. Does the Surgical Apgar Score predict serious complications after elective major cancer surgery? Journal of Surgical Research, 231:242-7, 2018.
Uzzo R.G., Novick A.C., Nephron sparing surgery for renal tumors: Indications, techniques and outcomes, 2001, Journal of Urology, 166, 1, 6, 18 PubMed
Kutikov A, Uzzo RG. The RENAL Nephrometry Score: A comprehensive standardized system for quantitating renal tumor size, location and depth. J Urol, 182(3):844-53, 2009. (cited 401 times) PubMed
Chawla S.N., Crispen P.L., Hanlon A.L., Greenberg R.E., Chen D.Y.T., Uzzo R.G., The natural history of observed enhancing renal masses: Meta-analysis and review of the world literature, 2006, Journal of Urology, 175, 2, 425, 431 PubMed
Kunkle D.A., Egleston B.L., Uzzo R.G., Excise, Ablate or Observe: The Small Renal Mass Dilemma-A Meta-Analysis and Review, 2008, Journal of Urology, 179, 4, 1227, 1234 PubMed
Kunkle D.A., Uzzo R.G., Cryoablation or radiofrequency ablation of the small renal mass: A meta-analysis, 2008, Cancer, 113, 10, 2671, 2680 PubMed
Uzzo R.G., Wei J.T., Waldbaum R.S., Perlmutter A.P., Byrne J.C., Vaughan Jr. D., The influence of prostate size on cancer detection, 1995, Urology, 46, 6, 831, 836 PubMed
Pollack A., Hanlon A.L., Horwitz E.M., Feigenberg S.J., Konski A.A., Movsas B., Greenberg R.E., Uzzo R.G., Ma C.-M.C., McNeeley S.W., Buyyounouski M.K., Price Jr. R.A., Dosimetry and preliminary acute toxicity in the first 100 men treated for prostate cancer on a randomized hypofractionation dose escalation trial, 2006, International Journal of Radiation Oncology Biology Physics, 64, 2, 518, 526 PubMed
Qiao J., Uzzo R., Obara-Ishihara T., Degenstein L., Fuchs E., Herzlinger D., FGF-7 modulates ureteric bud growth and nephron number in the developing kidney, 1999, Development, 126, 3, 547, 554
Lane B.R., Russo P., Uzzo R.G., Hernandez A.V., Boorjian S.A., Thompson R.H., Fergany A.F., Love T.E., Campbell S.C., Comparison of cold and warm ischemia during partial nephrectomy in 660 solitary kidneys reveals predominant role of nonmodifiable factors in determining ultimate renal function, 2011, Journal of Urology, 185, 2, 421, 427 PubMed
Mann S.J., Pickering T.G., Sos T.A., Uzzo R.G., Sarkar S., Friend K., Rackson M.E., Laragh J.H., Captopril renography in the diagnosis of renal artery stenosis: accuracy and limitations, 1991, The American Journal of Medicine, 90, 1, 30, 40 PubMed
Dulaimi E., Uzzo R.G., Greenberg R.E., Al-Saleem T., Cairns P., Detection of Bladder Cancer in Urine by a Tumor Suppressor Gene Hypermethylation Panel, 2004, Clinical Cancer Research, 10, 6, 1887, 1893 PubMed
Kunkle D.A., Crispen P.L., Chen D.Y.T., Greenberg R.E., Uzzo R.G., Enhancing Renal Masses With Zero Net Growth During Active Surveillance, 2007, Journal of Urology, 177, 3, 849, 854 PubMed
Touijer K., Jacqmin D., Kavoussi L.R., Montorsi F., Patard J.J., Rogers C.G., Russo P., Uzzo R.G., Van Poppel H., The Expanding Role of Partial Nephrectomy: A Critical Analysis of Indications, Results, and Complications, 2010, European Urology, 57, 2, 214, 222 PubMed
Additional Publications
Related Articles
46 PATIENT COMMENTS
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5.0
June 25, 2019
Good.
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5.0
June 19, 2019
I am a cancer survivor thanks to Dr. Uzzo and Fox Chase Cancer. [...]
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5.0
June 16, 2019
Good experience, as usual.
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5.0
June 12, 2019
Have been coming to Dr Uzzo for eight years and wouldn't go anywhere else. He takes his time with you and explains everything so you understand what he's talking about. The staff is great also.
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5.0
June 02, 2019
Dr. Uzzo and his team give top notch care with kindness and compassion. I am very thankful that I am under his care.
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5.0
May 27, 2019
I believe that Dr. Uzzo & his staff through their professionalism & compassion helped me to be in the very best condition before & after surgery.
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5.0
May 21, 2019
Dr. Uzzo , Always very concern about how I am doing, he listens and answers the way I can understand him I can not say enough about him... Love this guy
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5.0
May 19, 2019
Dr. Uzzo & staff are excellent.
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5.0
May 16, 2019
I have always had a good experience with the dr. and staff.
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5.0
May 12, 2019
Excellent treatment!
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5.0
April 29, 2019
Dr Uzzo is a great doctor
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5.0
April 25, 2019
I drive all of the way from [...], Delaware to see Dr. Uzzo because of Fox Chase Cancer Center's reputation but also because Dr. Uzzo is second to none.
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5.0
April 18, 2019
very good overall
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5.0
April 11, 2019
Dr Uzzo and his staff are outstanding!
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5.0
March 26, 2019
great doctor & staff
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5.0
March 21, 2019
Dr. Uzzo - [...] EXCELLENT!
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5.0
March 19, 2019
The provider and staff were all very helpful and courteous. Would definitely recommend the provider and his office.
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5.0
March 19, 2019
excellent staff, fantastic doctor! he listened to all of our concerns & provided us with all the information we needed.
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5.0
March 18, 2019
Best healthcare experience possible.
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5.0
March 16, 2019
Dr ,uzzo,s staff is the best in the system because he is the best and he chooses his staff.
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