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Robert G. Uzzo, MD, FACS

Robert Uzzo, MD, FACS

Clinical Locations

Primary Location

Huntingdon Pike
8 Huntingdon Pike
Rockledge, PA

Secondary Location

Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111

About

Chair, Department of Surgical Oncology

G. Willing "Wing" Pepper Chair in Cancer Research

Kidney, Bladder, and Prostate Cancer TRDG Member

Senior Vice-President, Physician Services

President, FCCC Medical Group, Inc.

Professor of Surgery, Temple University Health System

Treatment Focus

  • Robotic and laparoscopic urologic oncology
  • Organ preservation (kidney, bladder, testicular and adrenal)
  • Non-surgical management of low risk urinary tumors
  • Complex urological reconstruction

Research Program

Key Awards

Philadelphia Magazine Top Docs 2018
     Urology

Treatment Philosophy

I believe in treating patients as I would my own family. I strive to communicate effectively with patients and family members at all levels. Through extensive discussions with my patients, I develop treatment plans that are both effective and acknowledge that quality of life issues are exceptionally important. I emphasize individually tailored treatments to help patients achieve success and limit treatment-related side effects which can affect quality of life.

I am sensitive to the particular issues regarding surgical treatment of genitourinary cancer, especially the physical and emotional effects on patients and their family. By fostering a doctor-patient relationship based on mutual respect and open dialogue, I encourage patients to become empowered managers of their care... Expand

Follow on Twitter: @FCUroOnc

Chair, Department of Surgical Oncology

Nationally known as a leader in the field of urologic oncology, Dr. Uzzo has made important clinical, scientific and educational contributions to the Department of Surgery.

A fellow of the American College of Surgeons, Uzzo has consistently ranked among Castle Connolly’s and Philadelphia magazine's "Top Docs" in urology. He is a national principal investigator for a clinical trial by the Eastern Cooperative Oncology Group to evaluate new, targeted therapies for kidney cancers and immunotherapy.  He is the author of more than 350 chapters, articles, books and abstracts on urologic tumors and has presented hundreds of regional, national and international lectures.

In addition to his extensive clinical practice, he oversees research laboratory initiatives studying molecular mechanisms of genitourinary cancers. In 2003, he was promoted from Associate Professor to Professor with tenure in Fox Chase's division of medical science... Expand

Education and Training

Educational Background

  • Fellow, Urologic Oncology, Cleveland Clinic Foundation
  • Fellow, Renal Transplantation and Renovascular Surgery, Cleveland Clinic Foundation
  • Chief Resident, Urology, New York Hospital-Cornell University Medical Center, New York, NY
  • Senior Resident, Urology, Memorial Sloan-Kettering Cancer Center, New York, NY
  • MD, Cornell Medical College, New York, NY, 1991
  • BS/BA, Union College, Schenectady, NY, 1989, Valedictorian

Certifications

  • Diplomate, American Board of Urology

Memberships

  • The American Urological Association
  • Member, American Association of Genitourinary Surgeons, AAGUS
  • Society of Urologic Oncology, Board of Directors
  • Society of Urologic Oncology, Clinical Trials Consortium, President 
  • Society of Urologic Oncology, Clinical Trials Consortium, Renal Program Chairman  
  • Board of Directors, SUO Clinical Trials Consortia, member-at-large  
  • Fox Chase Cancer Center Society of Scholars  
  • Kidney Cancer Association Medical Advisory Board  
  • Fellow American College of Surgeons (F.A.C.S.)  
  • Society of Urologic Oncology  
  • Pennsylvania Medical Society
  • Philadelphia County Medical Society  
  • The MidAtlantic Section of the American Urological Association
  • Eastern Cooperative Oncology Group  
  • Radiation Therapy Oncology Group
  • American College of Surgeons Oncology Group - Vice Chairman, GU Organ Committee   2002-2006 
  • American Society of Transplant Surgeons 
  • Urologic Society of Transplant and Vascular Surgeons
  • Society for Basic Urologic Research  
  • American Association for Cancer Research

Honors & Awards

  • Philadelphia Magazine Top Doctors, 2002-18
  • America’s Top Doctors®, 2008-17
  • Best Doctors in America®, 2013-16
  • AUA Residents National Committee Teaching Award
  • Consumer’s Research Council of America –America’s Top Physicians 
Patient Stories

Fred Cohen

Bladder Cancer

Fred Cohen

Bladder Cancer

"Two dates are seared into my memory. On November 30, 2015, my wife and I were attending a funeral for a very dear friend, who had died after a long ordeal with kidney cancer. After the viewing I used the restroom and I noticed something unusual – blood in my urine. Obviously concerned, I called my urologist in the car on the way to the cemetery. He recommended I come in right away for an exam. On January 7, 2016, after weeks of tests and exams, the suspicion was confirmed: I had bladder cancer."

John Roley

Kidney Cancer

John Roley

Kidney Cancer

In the fall of 2007, John Roley was shocked to learn he had kidney cancer after experiencing severe stomach pain. After meeting with his doctor, he decided to get a second opinion from Dr. Robert Uzzo, chief of surgical oncology at Fox Chase Cancer Center. Rather than traditional surgery, Dr. Uzzo recommended two surgeries using the minimally-invasive da Vinci robotic surgical procedure that makes tiny incisions, results in very little scarring, and produces almost no bleeding. After the surgeries, John had no complications, healed quickly, and returned to work within weeks. "The doctors and nurses at Fox Chase were simply great in taking care of me and helping me to recover so quickly," he said. "I am forever grateful to everyone who found the problem, fixed the problem, and restored me to excellent health, and I pray that they are able to help others the way they helped me."

Denise Coldwater

Kidney Cancer

Denise Coldwater

Kidney Cancer

Based on my history with cancer, I often feel like the luckiest person on earth. In 1999, at the age of 45, I was diagnosed with kidney cancer. At the time, my only choice was a total nephrectomy (removal of the kidney).

Mike Phillips

Kidney Cancer;  Prostate Cancer

Mike Phillips

Kidney Cancer;  Prostate Cancer

When Mike Phillips was diagnosed with kidney cancer, he sought treatment at Fox Chase Cancer Center, where he underwent a partial nephrectomy. Unfortunately, the cancer returned six years later, in 2011, and this time both kidneys were affected. During this time, Mike was also having other health complications, including prostate cancer and a left hemispheric stroke that had no residual effects. In 2015, he received a kidney transplant and has been doing well since. "Now, fully recovered, I continue to do part-time business consulting, given my 45 years of business experience, 30 years in the world of franchising, and 15 in senior care/housing," Mike said, adding, "I hope to start volunteering soon at Fox Chase to provide phone counseling for patients who are dealing with cancer. My advice to others is to be the boss; it is your body, and you must be the captain of your ship."

Joe Riehs

Kidney Cancer

Joe Riehs

Kidney Cancer

"I received the call that I will never forget while I was high above the Delaware River on the Betsy Ross Bridge, between Pennsylvania and New Jersey, working for the Port Authority as a maintenance technician. My doctor called with the news: There was an 85 percent chance that the tumor found on my kidney was cancerous."

Pages

Research Profile

Research Program

Research Interests

  • Clinical and translational questions involving renal cell carcinoma including decision making models in the management of renal cancers and processes/quality of care in urologic malignancies
  • Analyses of outcomes involving excision, ablation, and active surveillance for localized kidney cancer and techniques/outcomes of surgery in locally advanced and metastatic RCC
  • Actively develop and accrue to multiple industry sponsored national and international urological oncology trials as well as investigator initiated trials.
  • Translational interests include biomarker development in kidney cancer and the role of zinc dyshomeostasis in prostate cancer
Publications

Selected Publications

Chapters and Publications from over 400:

Campbell S.C., Novick A.C., Belldegrun A., Blute M.L., Chow G.K., Derweesh I.H., Faraday M.M., Kaouk J.H., Leveillee R.J., Matin S.F., Russo P., Uzzo R.G., Guideline for Management of the Clinical T1 Renal Mass, 2009, Journal of Urology, 182, 4 SUPPL., 1271, 1279 PubMed

Goel N, Manstein SM, Ward WH, DeMora L, Smaldone MC, Farma JM, Uzzo RG, Esnaola NF. Does the Surgical Apgar Score predict serious complications after elective major cancer surgery? Journal of Surgical Research, 231:242-7, 2018. 

Uzzo R.G., Novick A.C., Nephron sparing surgery for renal tumors: Indications, techniques and outcomes, 2001, Journal of Urology, 166, 1, 6, 18 PubMed

Kutikov A, Uzzo RG. The RENAL Nephrometry Score: A comprehensive standardized system for quantitating renal tumor size, location and depth. J Urol, 182(3):844-53, 2009. (cited 401 times) PubMed

Chawla S.N., Crispen P.L., Hanlon A.L., Greenberg R.E., Chen D.Y.T., Uzzo R.G., The natural history of observed enhancing renal masses: Meta-analysis and review of the world literature, 2006, Journal of Urology, 175, 2, 425, 431 PubMed

Kunkle D.A., Egleston B.L., Uzzo R.G., Excise, Ablate or Observe: The Small Renal Mass Dilemma-A Meta-Analysis and Review, 2008, Journal of Urology, 179, 4, 1227, 1234 PubMed

Kunkle D.A., Uzzo R.G., Cryoablation or radiofrequency ablation of the small renal mass: A meta-analysis, 2008, Cancer, 113, 10, 2671, 2680 PubMed

Uzzo R.G., Wei J.T., Waldbaum R.S., Perlmutter A.P., Byrne J.C., Vaughan Jr. D., The influence of prostate size on cancer detection, 1995, Urology, 46, 6, 831, 836 PubMed

Pollack A., Hanlon A.L., Horwitz E.M., Feigenberg S.J., Konski A.A., Movsas B., Greenberg R.E., Uzzo R.G., Ma C.-M.C., McNeeley S.W., Buyyounouski M.K., Price Jr. R.A., Dosimetry and preliminary acute toxicity in the first 100 men treated for prostate cancer on a randomized hypofractionation dose escalation trial, 2006, International Journal of Radiation Oncology Biology Physics, 64, 2, 518, 526 PubMed

Qiao J., Uzzo R., Obara-Ishihara T., Degenstein L., Fuchs E., Herzlinger D., FGF-7 modulates ureteric bud growth and nephron number in the developing kidney, 1999, Development, 126, 3, 547, 554

Lane B.R., Russo P., Uzzo R.G., Hernandez A.V., Boorjian S.A., Thompson R.H., Fergany A.F., Love T.E., Campbell S.C., Comparison of cold and warm ischemia during partial nephrectomy in 660 solitary kidneys reveals predominant role of nonmodifiable factors in determining ultimate renal function, 2011, Journal of Urology, 185, 2, 421, 427 PubMed

Mann S.J., Pickering T.G., Sos T.A., Uzzo R.G., Sarkar S., Friend K., Rackson M.E., Laragh J.H., Captopril renography in the diagnosis of renal artery stenosis: accuracy and limitations, 1991, The American Journal of Medicine, 90, 1, 30, 40 PubMed

Dulaimi E., Uzzo R.G., Greenberg R.E., Al-Saleem T., Cairns P., Detection of Bladder Cancer in Urine by a Tumor Suppressor Gene Hypermethylation Panel, 2004, Clinical Cancer Research, 10, 6, 1887, 1893 PubMed

Kunkle D.A., Crispen P.L., Chen D.Y.T., Greenberg R.E., Uzzo R.G., Enhancing Renal Masses With Zero Net Growth During Active Surveillance, 2007, Journal of Urology, 177, 3, 849, 854 PubMed

Touijer K., Jacqmin D., Kavoussi L.R., Montorsi F., Patard J.J., Rogers C.G., Russo P., Uzzo R.G., Van Poppel H., The Expanding Role of Partial Nephrectomy: A Critical Analysis of Indications, Results, and Complications, 2010, European Urology, 57, 2, 214, 222 PubMed

Additional Publications

My NCBI

Ratings

254 PATIENT SATISFACTION REVIEWS

Our Patient Satisfaction Rating is an average of all responses to care provider related questions from our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more.

OVERALL RATING

4.9 / 5.0

RATINGS BREAKDOWN

  • 4.9
  • 4.9
  • 5.0
  • 5.0
  • 4.9

24 PATIENT COMMENTS

  • 5.0
    June 28, 2018
    Care is superb, instructions and explanations are very clear to understand while at the same time provider and staff are very open about answering questions. Thank you
  • 5.0
    June 21, 2018
    I had an excellent experience working with the staff at Fox Chase, Dr. Uzzo is a consummate professional, I would recommend him to anyone.
  • 5.0
    June 13, 2018
    Dr. Uzzo is absolutely amazing. I can say enough great things about him.
  • 5.0
    June 03, 2018
    The best possible results after exam.
  • 5.0
    June 01, 2018
    Dr. Uzzo and all his staff and colleagues ARE OUT STANDING, THOROUGH, EMULATE CONFIDENCE AND FOCUS CARE ON THE PATIENT AND FAMILY.
  • 5.0
    May 22, 2018
    I was lucky to be able to see Dr. Uzzo for my prostate cancer. I feel 100% confident in his decisions.
  • 5.0
    May 12, 2018
    Excellent care
  • 5.0
    May 10, 2018
    3 appointments in each visit. (1) MRI for kidney cists.....perfect. No waiting. very kind and professional. (2) Blood work....no waiting and very professional. (3) individual visit to Uzzo off campus office. 1:15 appointment. Was put in too at 1:30 (office nit busy) and was NOT seen until 2:50 after getting upset. [...] Very unprofessional to leave a patient unattended for almost 2 hours.
  • 5.0
    May 10, 2018
    Dr. Uzzo is a kind compassionate doctor. I consider him a genus surgeon who cured me of my kidney cancer.
  • 5.0
    May 05, 2018
    always very nice
  • 5.0
    April 27, 2018
    caring. kind and helpful.
  • 5.0
    April 26, 2018
    In the 4 years [...] I have been treated by Dr. Uzzo and Fox Chase, I have ALWAYS felt I have put my life into the best possible hands to manage my bladder cancer.
  • 4.0
    April 26, 2018
    If I knew of someone who had a renal carcinoma I would definitely refer them to Dr Uzzo. [...]
  • 5.0
    April 19, 2018
    I' ve been seeing Dr.Uzzo for over 15 years. Great doc
  • 5.0
    April 14, 2018
    good
  • 5.0
    April 04, 2018
    Dr. Uzzo is the best doctor I have ever seen.
  • 4.5
    April 04, 2018
    Very booked & pressed for time.
  • 5.0
    March 22, 2018
    Knowledgeable, professional, kind, and courteous has been my experience with Dr Uzzo and his team.l
  • 5.0
    March 15, 2018
    As the kids would say, "Dr. Uzzo rules!"
  • 5.0
    March 14, 2018
    Great physician; excellent at explaining treatments, outcomes, future considerations, reasons for followups.
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