Robert Uzzo, MD, MBA, FACS

Robert Uzzo, MD, FACS
(4.9/5.0)
330 Patient Satisfaction Ratings
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Clinical Locations

President & CEO, Fox Chase Cancer Center

G. Willing "Wing" Pepper Chair in Cancer Research

Professor, Department of Surgery

Professor of Surgery, Temple University Health System

Adjunct Professor of Bioengineering, Temple University College of Engineering

Treatment Focus

  • Robotic and laparoscopic urologic oncology
  • Organ preservation (kidney, bladder, testicular and adrenal)
  • Non-surgical management of low risk urinary tumors
  • Complex urological reconstruction

Research Program

Key Awards

Philadelphia Magazine Top Docs 2022
Urology

Treatment Philosophy

I believe in treating patients as I would my own family. I strive to communicate effectively with patients and family members at all levels. Through extensive discussions with my patients, I develop treatment plans that are both effective and acknowledge that quality of life issues are exceptionally important. I emphasize individually tailored treatments to help patients achieve success and limit treatment-related side effects which can affect quality of life.

I am sensitive to the particular issues regarding surgical treatment of genitourinary cancer, especially the physical and emotional effects on patients and their family. By fostering a doctor-patient relationship based on mutual respect and open dialogue, I encourage patients to become empowered managers of their care.

As a fellowship-trained laparoscopic and robotic urologic oncologist, I am specially trained in nerve-sparing, organ sparing and organ reconstructive surgical techniques for men and women. These strategies are essential for preserving normal functions. For instance, I perform kidney sparing surgery whenever possible to avoid future risks of dialysis. For prostate or testicular surgery, nerve preservation is essential; and when bladder removal is necessary, reconstruction of a new (neobladder) is my preferred approach.

Professionally, I have published more than 300 journal papers in urologic oncology and have lectured extensively regionally, nationally and internationally on the topics of kidney, prostate, bladder, and testicular cancer. I am the principle investigator or co-investigator on multiple national and regional clinical trials in urologic oncology. Because of my research and extensive membership in professional organizations, I am among the first to know what is new in urologic cancer treatment. Philadelphia magazine has chosen me for its "Top Doctors" list every year since 2002.

Bio

As President & CEO, Fox Chase Cancer Center, Robert Uzzo is responsible for leading the overall clinical operations of Fox Chase. In his role as Chair of the Department of Surgery, he leads the surgery efforts and oversees research laboratory initiatives to study molecular mechanisms of genitourinary cancers.

In addition to these roles, Uzzo is the G. Willing “Wing” Pepper Chair in Cancer Research and also serves as the organization’s President of the Medical Group. He also serves as the founding Executive Director of the nation’s second largest urologic quality collaborative, the Pennsylvania Urologic Regional Collaborative.

Uzzo’s primary research has been in renal cell carcinoma, with a special focus on clinical decision making, surgical management, and adjuvant therapies. He has been a principal investigator, investigator, or co-principal investigator on dozens of leading national and international trials in urinary cancers that have had a major impact on the field of urology. In addition, he is the developer of the NEPHROMETRY scoring system, which is used to delineate the complexity of renal tumors and impact of care.

Uzzo is a diplomat of the American Board of Urology, a fellow of the American College of Surgeons, and an elected member of both the prestigious American Association of Genitourinary Surgeons and the Clinical Society of GU Surgeons. He has served as visiting professor at over 50 institutions around the world, trained dozens of residents and fellows, holds six patents, and has been principal investigator or co-principal investigator on dozens of grants. His publication of over 900 peer reviewed articles, chapters and abstracts have been cited nearly 20,000 times in the literature

Uzzo graduated summa cum laude and as valedictorian from Union College’s accelerated six-year Biomedical Program. He attended Cornell University Medical College, where he was a New York State Finalist for the Rhodes Scholarship competition. He completed general surgical training followed by urologic surgical training at New York-Presbyterian/Weill Cornell Medical Center and Memorial Sloan Kettering Cancer Center. He was an American Foundation for Urological Diseases Scholar in Urological Oncology and completed both oncological and renal transplantation fellowships at Cleveland Clinic before joining Fox Chase in 2000.

 

View Dr. Uzzo's PracticeUpdate contributions

Educational Background

  • Fellow, Urologic Oncology, Cleveland Clinic Foundation
  • Fellow, Renal Transplantation and Renovascular Surgery, Cleveland Clinic Foundation
  • Chief Resident, Urology, New York Hospital-Cornell University Medical Center, New York, NY
  • Senior Resident, Urology, Memorial Sloan-Kettering Cancer Center, New York, NY
  • MD, Cornell Medical College, New York, NY, 1991
  • BS/BA, Union College, Schenectady, NY, 1987, Valedictorian

Certifications

  • Diplomate, American Board of Urology

Memberships

  • The American Urological Association
  • Member, American Association of Genitourinary Surgeons, AAGUS
  • Society of Urologic Oncology, Board of Directors
  • Society of Urologic Oncology, Clinical Trials Consortium, President 
  • Society of Urologic Oncology, Clinical Trials Consortium, Renal Program Chairman  
  • Board of Directors, SUO Clinical Trials Consortia, member-at-large  
  • Fox Chase Cancer Center Society of Scholars  
  • Kidney Cancer Association Medical Advisory Board  
  • Fellow American College of Surgeons (F.A.C.S.)  
  • Society of Urologic Oncology  
  • Pennsylvania Medical Society
  • Philadelphia County Medical Society  
  • The MidAtlantic Section of the American Urological Association
  • Eastern Cooperative Oncology Group  
  • Radiation Therapy Oncology Group
  • American College of Surgeons Oncology Group - Vice Chairman, GU Organ Committee   2002-2006 
  • American Society of Transplant Surgeons 
  • Urologic Society of Transplant and Vascular Surgeons
  • Society for Basic Urologic Research  
  • American Association for Cancer Research

Honors & Awards

  • Philadelphia Magazine Top Doctors, 2002-20
  • Best Doctors in America®, 2013-16, 2019-2020, Urology
  • America’s Top Doctors®, 2008-17
  • AUA Residents National Committee Teaching Award
  • Consumer’s Research Council of America –America’s Top Physicians 

Norm Faus III

  • Kidney Cancer

My name is Norm Faus III. I live in Lititz, Pennsylvania, which is about 80 miles west of Philadelphia. My wife and I have been married for 53 years. We have two grown children and several grandchildren. That makes me an old man of 73.

Generally, I’ve been very healthy over the years. The only thing I did develop, about 20 years ago, is peripheral neuropathy. It was what the doctors call idiopathic, meaning I didn’t have diabetes or cancer or anything that would have caused it to develop. Otherwise, I haven’t had any serious health issues.

VIEW PATIENT STORY

Research Interests

  • Clinical and translational questions involving renal cell carcinoma including decision making models in the management of renal cancers and processes/quality of care in urologic malignancies
  • Analyses of outcomes involving excision, ablation, and active surveillance for localized kidney cancer and techniques/outcomes of surgery in locally advanced and metastatic RCC
  • Actively develop and accrue to multiple industry sponsored national and international urological oncology trials as well as investigator initiated trials.
  • Translational interests include biomarker development in kidney cancer and the role of zinc dyshomeostasis in prostate cancer

Selected Publications

Chapters and Publications from over 400:

Correa A.F., Jegede O.A., Haas N.B., Flaherty K.T., Pins M.R., Adeniran A., Messing E.M., Manola J., Wood C.G., Kane C.J., Jewett M.A.S., Dutcher J.P., DiPaola R.S., Carducci M.A., Uzzo R.G., Predicting disease recurrence, early progression, and overall survival following surgical resection for high-risk localized and locally advanced renal cell carcinoma. Eur Urol. 80(1): 20-31, 2021. PMC8627688. https://www.ncbi.nlm.nih.gov/pubmed/33707112.

Smith S.M., Wachter K., Burris H.A., 3rd, Schilsky R.L., George D.J., Peterson D.E., Johnson M.L., Markham M.J., Mileham K.F., Beg M.S., Bendell J.C., Dreicer R., Keedy V.L., Kimple R.J., Knoll M.A., LoConte N., MacKay H., Meisel J.L., Moynihan T.J., Mulrooney D.A., Mulvey T.M., Odenike O., Pennell N.A., Reeder-Hayes K., Smith C., Sullivan R.J., Uzzo R., Clinical cancer advances 2021: Asco's report on progress against cancer. J Clin Oncol. 39(10): 1165-1184, 2021. https://www.ncbi.nlm.nih.gov/pubmed/33527845.

Campbell S.C., Novick A.C., Belldegrun A., Blute M.L., Chow G.K., Derweesh I.H., Faraday M.M., Kaouk J.H., Leveillee R.J., Matin S.F., Russo P., Uzzo R.G., Guideline for Management of the Clinical T1 Renal Mass, 2009, Journal of Urology, 182, 4 SUPPL., 1271, 1279 PubMed

Goel N, Manstein SM, Ward WH, DeMora L, Smaldone MC, Farma JM, Uzzo RG, Esnaola NF. Does the Surgical Apgar Score predict serious complications after elective major cancer surgery? Journal of Surgical Research, 231:242-7, 2018. 

Uzzo R.G., Novick A.C., Nephron sparing surgery for renal tumors: Indications, techniques and outcomes, 2001, Journal of Urology, 166, 1, 6, 18 PubMed

Kutikov A, Uzzo RG. The RENAL Nephrometry Score: A comprehensive standardized system for quantitating renal tumor size, location and depth. J Urol, 182(3):844-53, 2009. (cited 401 times) PubMed

Chawla S.N., Crispen P.L., Hanlon A.L., Greenberg R.E., Chen D.Y.T., Uzzo R.G., The natural history of observed enhancing renal masses: Meta-analysis and review of the world literature, 2006, Journal of Urology, 175, 2, 425, 431 PubMed

Kunkle D.A., Egleston B.L., Uzzo R.G., Excise, Ablate or Observe: The Small Renal Mass Dilemma-A Meta-Analysis and Review, 2008, Journal of Urology, 179, 4, 1227, 1234 PubMed

Kunkle D.A., Uzzo R.G., Cryoablation or radiofrequency ablation of the small renal mass: A meta-analysis, 2008, Cancer, 113, 10, 2671, 2680 PubMed

Uzzo R.G., Wei J.T., Waldbaum R.S., Perlmutter A.P., Byrne J.C., Vaughan Jr. D., The influence of prostate size on cancer detection, 1995, Urology, 46, 6, 831, 836 PubMed

Pollack A., Hanlon A.L., Horwitz E.M., Feigenberg S.J., Konski A.A., Movsas B., Greenberg R.E., Uzzo R.G., Ma C.-M.C., McNeeley S.W., Buyyounouski M.K., Price Jr. R.A., Dosimetry and preliminary acute toxicity in the first 100 men treated for prostate cancer on a randomized hypofractionation dose escalation trial, 2006, International Journal of Radiation Oncology Biology Physics, 64, 2, 518, 526 PubMed

Qiao J., Uzzo R., Obara-Ishihara T., Degenstein L., Fuchs E., Herzlinger D., FGF-7 modulates ureteric bud growth and nephron number in the developing kidney, 1999, Development, 126, 3, 547, 554

Lane B.R., Russo P., Uzzo R.G., Hernandez A.V., Boorjian S.A., Thompson R.H., Fergany A.F., Love T.E., Campbell S.C., Comparison of cold and warm ischemia during partial nephrectomy in 660 solitary kidneys reveals predominant role of nonmodifiable factors in determining ultimate renal function, 2011, Journal of Urology, 185, 2, 421, 427 PubMed

Mann S.J., Pickering T.G., Sos T.A., Uzzo R.G., Sarkar S., Friend K., Rackson M.E., Laragh J.H., Captopril renography in the diagnosis of renal artery stenosis: accuracy and limitations, 1991, The American Journal of Medicine, 90, 1, 30, 40 PubMed

Dulaimi E., Uzzo R.G., Greenberg R.E., Al-Saleem T., Cairns P., Detection of Bladder Cancer in Urine by a Tumor Suppressor Gene Hypermethylation Panel, 2004, Clinical Cancer Research, 10, 6, 1887, 1893 PubMed

Kunkle D.A., Crispen P.L., Chen D.Y.T., Greenberg R.E., Uzzo R.G., Enhancing Renal Masses With Zero Net Growth During Active Surveillance, 2007, Journal of Urology, 177, 3, 849, 854 PubMed

Touijer K., Jacqmin D., Kavoussi L.R., Montorsi F., Patard J.J., Rogers C.G., Russo P., Uzzo R.G., Van Poppel H., The Expanding Role of Partial Nephrectomy: A Critical Analysis of Indications, Results, and Complications, 2010, European Urology, 57, 2, 214, 222 PubMed

Additional Publications

330 patient satisfaction reviews

Our Patient Satisfaction Rating is an average of all responses to care provider related questions from our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more.

Overall Rating

4.9 / 5.0

Ratings Breakdown

4.9
Gives easy to understand instruction
4.9
Explains in a way you understand
5.0
Listens carefully to you
5.0
Shows respect for what you say
4.9
Spends enough time with you

84 patient comments

  • 5.0
    March 28, 2022

    Dr.Uzzo and his team are some of the best that I have ever met. They are concerned about all my medical difficulties. I truly trust him and his team to get me thru these difficult times. They took there time during my appointment and explained everything so I could understand what needs to be done.

  • 5.0
    March 27, 2022

    Great experience

  • 5.0
    March 22, 2022

    I am so grateful for this wonderful care. Superior.

  • 5.0
    March 21, 2022

    I felt very comfortable when I first arrived and left feeling very confident that I came to the right place.

  • 5.0
    March 21, 2022

    Every visit w/a Fox Chase dr. or dept. has been a 1st class experience (scans, blood work etc.).

  • 5.0
    March 18, 2022

    Very good first experience. (New patient).

  • No Star Ratings Available
    March 12, 2022

    Very good

  • 5.0
    March 9, 2022

    Great experience in all aspects.

  • No Star Ratings Available
    March 5, 2022

    Thorough, clear, all questions answered pleasantly

  • 5.0
    March 4, 2022

    This was my initial visit and it was a good one.

  • No Star Ratings Available
    February 28, 2022

    Explained thoroughly, clearly, answering my question.

  • 5.0
    February 25, 2022

    Would recommend to anyone having similar issues.

  • 5.0
    February 25, 2022

    Dr. Uzzo & his team are vivid examples of outstanding health care.

  • 5.0
    February 9, 2022

    Very good experience.

  • 5.0
    January 31, 2022

    The whole team is very good!!

  • 5.0
    December 21, 2021

    I have been treated by Dr. Uzzo and the Urology clinic for the last 8+ years. I have never experienced anything but the best possible service and care, in every respect.

  • 5.0
    December 21, 2021

    The nurses and staff could not have been any better. I was amazed and felt very cared for and safe. Excellent job. I cannot praise all of you enough.

  • 5.0
    December 10, 2021

    Dr. Uzzo and the entire staff are amazingly pleasant, helpful and efficient beyond belief. Truly impressed with FCCC thus far and hope this continues through my upcoming surgery.

  • 5.0
    November 29, 2021

    Dr. Uzzo and staff are just wonderful. They make you feel at ease and have such concern.

  • 5.0
    November 2, 2021

    Dr. Uzzo, the resident doctor, and Nurse [...] were engaging, encouraging, and knowledgeable - I felt safe and in excellent hands.

  • 5.0
    November 1, 2021

    Always a reassuring visit with Dr. Uzzo.

  • 5.0
    October 25, 2021

    Dr Uzzo is clearly a great doctor and he made me and my wife feel very confident in his assessment of my current condition.

  • 5.0
    October 8, 2021

    What a wonderful care environment; from front desk, through nursing to physician. Appointments made with due consideration, promptly visible on the app. No cause for complaint; many reasons to be grateful at the quality of care & compassion.

  • 5.0
    October 5, 2021

    Was as pleasant as a doctor appointment could be. Dr. Izzy gave crystal clear explanations of what was happening.

  • No Star Ratings Available
    October 5, 2021

    Great healthcare provider, good listener, experienced and very Intelligent, very caring. ,

  • 5.0
    October 1, 2021

    It was a very good experience and handled with the utmost care of my problem.

  • 5.0
    September 20, 2021

    Dr Uzzo is awesome and Fox Chase is the best!

  • 5.0
    September 18, 2021

    Dr. Uzzo and his assistant gave me a priceless education that was informative and right on point making me 100% aware of my condition and what I'm facing with no bs ahead of me. These guys care immensely and it shows. Thank you.

  • 5.0
    September 11, 2021

    Most caring and compassionate Dr I ever visited. I would recommend Dr Uzzo to everyone I know

  • 5.0
    September 7, 2021

    What a knowledgeable ands compassionate doctor (Uzzo), and what a comforting team!

  • 5.0
    September 1, 2021

    My Experience with Dr.Uzzo and staff was AWESOME!!!!!!!!!

  • 5.0
    August 31, 2021

    Good experience

  • 5.0
    August 20, 2021

    Thank you Dr Uzzo and staff!

  • 5.0
    August 18, 2021

    Dr. Uzzo and his staff are warm and welcoming. They are so organized and efficient it is a pleasure. Having had kidney cancer it is comforting when the staff is professional and and knows what they are doing. Can't say enough good things about this practice!

  • No Star Ratings Available
    August 13, 2021

    Dr. Uzzo is one of the BEST doctors I ever met! He is just outstanding!

  • 5.0
    August 13, 2021

    I Love Dr UZZO and his staff !!!

  • 5.0
    August 12, 2021

    Dr. Uzzo and his staff ALWAYS TREAT me with kindness and class.

  • 5.0
    August 10, 2021

    Very professional, respectful, patient, and compassionate - I felt safe, understood, and genuinely cared for.

  • 5.0
    August 6, 2021

    [...] He then called me to discuss my test results. He also needed to contact another dr regarding the results and got back to me very quickly. He is the best doctor I've ever been too and he truly cares about his patients. This is the kind of doctor all patients should have access to when they have serious health issues.

  • 5.0
    August 6, 2021

    Dr. UZZO and his team were excellent!I know that my dad Is In the best hands and he will be OK.Dr. Uzzo gave us detailed action plan and gave us so much confidence in my dad's future. Can't THANK him enough.

  • 5.0
    July 29, 2021

    Dr. Uzzo impressed me by drawing a picture of my kidneys and explained my problem in detail. He took as much time I need to answer my questions. Dr. Uzzo was personable, friendly and very interested in my case to help me. I grade Dr. Uzzo A+.

  • 5.0
    July 28, 2021

    Dr Uzzo is the best ever. He was recommended to me by another doctor, and a former patient. He truly respects me & my health in a manner that has made him #1 with me & his profession.

  • 5.0
    July 28, 2021

    Always feel they have my best interest at heart.

  • No Star Ratings Available
    July 28, 2021

    Excellent, excellent doctor

  • 5.0
    July 27, 2021

    Dr. Uzzo and staff were very nice and explained everything in detail. I was very comfortable having him as my Dr/surgeon.

  • No Star Ratings Available
    July 25, 2021

    Good Experience

  • 5.0
    July 24, 2021

    Overall excellent experience. I have a lots of anxiety time I have to go in for a cystoscope. I have complete confidence in my doctor and I appreciate that he tries to put me at ease during the somewhat uncomfortable procedure. The nurses, too, make the experience so much easier. They are so kind, helpful and supportive, and the front desk people are always very pleasant and efficient.

  • 5.0
    July 24, 2021

    Good experience.

  • 5.0
    July 24, 2021

    Dr. Uzzo, his assistants, and the staff at Fox Chase have my highest regards and would receive my top recommendation.

  • 5.0
    July 24, 2021

    Dr. Uzzo is the best! Definitely credit him for saving my kidney.I am grateful he continues to watch my condition!

  • 5.0
    July 24, 2021

    Amazing, thorough, and mostly kind and friendly.

  • 5.0
    July 21, 2021

    Outstanding care from an outstanding team led by an outstanding physician.

  • 5.0
    June 24, 2021

    Great provider.

  • 5.0
    May 21, 2021

    As always a wonderful experience.

  • 5.0
    April 30, 2021

    Great experience made myself & Wife feel much better about my current health status.

  • 5.0
    April 27, 2021

    Excellent care & service. 5 stars to doctor, nurse & staff.

  • 5.0
    April 23, 2021

    Keep it as great as it is. I think it is the best. I'm very happy to be associated with Dr. Uzzo, the professional staff, and all members of Fox Chase. Thank you very much. [...]

  • No Star Ratings Available
    April 23, 2021

    Broke down the diagnosis as well as options very well

  • 5.0
    April 16, 2021

    Good experience

  • 5.0
    April 16, 2021

    Thank you for the opinion as to what we need to do.

  • No Star Ratings Available
    April 6, 2021

    Provided input on another issue found during the ultra sound and sent information to my family and specialist doctors.

  • No Star Ratings Available
    April 4, 2021

    Very friendly and answered all questions. A+ doctor.

  • 5.0
    April 2, 2021

    Efficient, prompt, caring and compassionate care

  • 5.0
    March 20, 2021

    Great Dr. Great staff

  • No Star Ratings Available
    March 17, 2021

    Dr Uzzo is patient, knowledgeable, and takes the time to ensure you are getting the best care possible.

  • No Star Ratings Available
    March 17, 2021

    excellent experience

  • 5.0
    March 8, 2021

    Doctor Uzzo and his staff have consistently been professional. Courteous, friendly & caring. He is my opinion, easily the best urologist on the East Coast.

  • 4.5
    March 7, 2021

    Very good experience

  • 5.0
    March 3, 2021

    Dr. Uzzo and the staff made me feel at ease during the visit. My anxiety was lessened. Everything was explained to me in terms that I could understand.

  • 5.0
    February 25, 2021

    Dr. Uzzo & his nurse [...] are great. Also his office staff are kind, thorough, efficient, etc.

  • 5.0
    February 19, 2021

    Dr. Uzzo knows how to deal with his patients . He knows that we worry and are stressed out waiting for the results and he is direct, to the point, gives you the info right away to relieve your stress right away. Then he proceeds with what he has to do. His patients come first. In regard to r ating Dr. Uzzo. You need to go higher than 10 to be ccurte.

  • 5.0
    February 19, 2021

    great, safe

  • 5.0
    January 30, 2021

    Doctor Uzzo is amazing I don't think I'd be alive if it weren't for him I'm grateful for his work ethic an pride he takes in his craft because I've seen doctors just tell you things to get you out of there but Doctor Uzzo treats every patient like as if they were his own family members I was very lucky

  • 5.0
    January 29, 2021

    I was treated as expected. Each time I had an appointment I was treated with respect,

  • 4.5
    January 26, 2021

    Have seen Dr. Uzzo many times as a surgical inpatient and outpatient. Am completely satisfied with the care provided by him and his team.

  • 5.0
    January 26, 2021

    [...] overall a pleasant & comfortable experience.

  • No Star Ratings Available
    January 25, 2021

    Dr. Uzzo is very knowledgeable and was able to explain what my options are for prostrate cancer

  • No Star Ratings Available
    January 24, 2021

    Dr. Uzzo is an amazing doctor and an amazing, caring individual.

  • 5.0
    January 22, 2021

    i couldn't get any better care than being Dr.Uzzu patient I new I was in good hands the day we met and after talking to him he made me feel completely confident about the surgery he was going to perform on me he is a great surgeon and a wonderful person

  • 5.0
    January 15, 2021

    Really went to extreme to help with my needs.

  • 5.0
    January 9, 2021

    I love the doctor and his staff

  • 5.0
    January 9, 2021

    My father's personal friend and trusted urologist highly recommended Dr. Uzzo. I went to Dr. Uzzo for a second opinion. My wife and I were not disappointed. Exceptional care from Dr. Uzzo and the staff. Much more thorough and informative. Dr. Uzzo related the information in a way that was readily understandable. The staff was courteous and professional. They went out of there way for me. Thank you.

  • No Star Ratings Available
    December 23, 2020

    Extremely pleased with the session

  • 5.0
    December 22, 2020

    Dr. Uzzo is an excellent physician. He is the BEST!!!