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Robert G. Uzzo, MD, MBA, FACS

Robert Uzzo, MD, FACS

Clinical Locations

Primary Location

Huntingdon Pike
8 Huntingdon Pike
Rockledge, PA

Secondary Location

Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111

About

Chairman, Department of Surgery

G. Willing "Wing" Pepper Chair in Cancer Research

Professor, Department of Surgery

Professor of Surgery, Temple University Health System

Adjunct Professor of Bioengineering, Temple University College of Engineering

Treatment Focus

  • Robotic and laparoscopic urologic oncology
  • Organ preservation (kidney, bladder, testicular and adrenal)
  • Non-surgical management of low risk urinary tumors
  • Complex urological reconstruction

Research Program

Key Awards

Philadelphia Magazine Top Docs 2019      Urology

Treatment Philosophy

I believe in treating patients as I would my own family. I strive to communicate effectively with patients and family members at all levels. Through extensive discussions with my patients, I develop treatment plans that are both effective and acknowledge that quality of life issues are exceptionally important. I emphasize individually tailored treatments to help patients achieve success and limit treatment-related side effects which can affect quality of life.

I am sensitive to the particular issues regarding surgical treatment of genitourinary cancer, especially the physical and emotional effects on patients and their family. By fostering a doctor-patient relationship based on mutual respect and open dialogue, I encourage patients to become empowered managers of their care... Expand

Follow on Twitter: @FCUroOnc

Chairman, Department of Surgery

Nationally known as a leader in the field of urologic oncology, Dr. Uzzo has made important clinical, scientific and educational contributions to the Department of Surgery.

A fellow of the American College of Surgeons, Uzzo has consistently ranked among Castle Connolly’s and Philadelphia magazine's "Top Docs" in urology. He is a national principal investigator for a clinical trial by the Eastern Cooperative Oncology Group to evaluate new, targeted therapies for kidney cancers and immunotherapy.  He is the author of more than 350 chapters, articles, books and abstracts on urologic tumors and has presented hundreds of regional, national and international lectures.

In addition to his extensive clinical practice, he oversees research laboratory initiatives studying molecular mechanisms of genitourinary cancers. In 2003, he was promoted from Associate Professor to Professor with tenure in Fox Chase's division of medical science... Expand

Education and Training

Educational Background

  • Fellow, Urologic Oncology, Cleveland Clinic Foundation
  • Fellow, Renal Transplantation and Renovascular Surgery, Cleveland Clinic Foundation
  • Chief Resident, Urology, New York Hospital-Cornell University Medical Center, New York, NY
  • Senior Resident, Urology, Memorial Sloan-Kettering Cancer Center, New York, NY
  • MD, Cornell Medical College, New York, NY, 1991
  • BS/BA, Union College, Schenectady, NY, 1989, Valedictorian

Certifications

  • Diplomate, American Board of Urology

Memberships

  • The American Urological Association
  • Member, American Association of Genitourinary Surgeons, AAGUS
  • Society of Urologic Oncology, Board of Directors
  • Society of Urologic Oncology, Clinical Trials Consortium, President 
  • Society of Urologic Oncology, Clinical Trials Consortium, Renal Program Chairman  
  • Board of Directors, SUO Clinical Trials Consortia, member-at-large  
  • Fox Chase Cancer Center Society of Scholars  
  • Kidney Cancer Association Medical Advisory Board  
  • Fellow American College of Surgeons (F.A.C.S.)  
  • Society of Urologic Oncology  
  • Pennsylvania Medical Society
  • Philadelphia County Medical Society  
  • The MidAtlantic Section of the American Urological Association
  • Eastern Cooperative Oncology Group  
  • Radiation Therapy Oncology Group
  • American College of Surgeons Oncology Group - Vice Chairman, GU Organ Committee   2002-2006 
  • American Society of Transplant Surgeons 
  • Urologic Society of Transplant and Vascular Surgeons
  • Society for Basic Urologic Research  
  • American Association for Cancer Research

Honors & Awards

  • Best Doctors in America® , 2013-16, 2019-2020, Urology
  • Philadelphia Magazine Top Doctors, 2002-19
  • America’s Top Doctors®, 2008-17
  • AUA Residents National Committee Teaching Award
  • Consumer’s Research Council of America –America’s Top Physicians 
Patient Stories

Charlie Smithgall

Kidney Cancer

Charlie Smithgall

Kidney Cancer

I love Lancaster, Pennsylvania. I’m 73 and I’ve lived in Lancaster my whole life. My family’s been a part of this town for more than 100 years. I own my family’s drugstore business that was started when my father opened a pharmacy in his mother’s living room in 1916. I even served as Mayor of Lancaster from 1998 to 2006, and I love my community. For the most part, things are peaceful. But in 2018, I almost lost everything. 

Fred Cohen

Bladder Cancer

Fred Cohen

Bladder Cancer

"Two dates are seared into my memory. On November 30, 2015, my wife and I were attending a funeral for a very dear friend, who had died after a long ordeal with kidney cancer. After the viewing I used the restroom and I noticed something unusual – blood in my urine. Obviously concerned, I called my urologist in the car on the way to the cemetery. He recommended I come in right away for an exam. On January 7, 2016, after weeks of tests and exams, the suspicion was confirmed: I had bladder cancer."

John Roley

Kidney Cancer

John Roley

Kidney Cancer

In the fall of 2007, John Roley was shocked to learn he had kidney cancer after experiencing severe stomach pain. After meeting with his doctor, he decided to get a second opinion from Dr. Robert Uzzo, chief of surgical oncology at Fox Chase Cancer Center. Rather than traditional surgery, Dr. Uzzo recommended two surgeries using the minimally-invasive da Vinci robotic surgical procedure that makes tiny incisions, results in very little scarring, and produces almost no bleeding. After the surgeries, John had no complications, healed quickly, and returned to work within weeks. "The doctors and nurses at Fox Chase were simply great in taking care of me and helping me to recover so quickly," he said. "I am forever grateful to everyone who found the problem, fixed the problem, and restored me to excellent health, and I pray that they are able to help others the way they helped me."

Denise Coldwater

Kidney Cancer

Denise Coldwater

Kidney Cancer

Based on my history with cancer, I often feel like the luckiest person on earth. In 1999, at the age of 45, I was diagnosed with kidney cancer. At the time, my only choice was a total nephrectomy (removal of the kidney).

Mike Phillips

Kidney Cancer;  Prostate Cancer

Mike Phillips

Kidney Cancer;  Prostate Cancer

When Mike Phillips was diagnosed with kidney cancer, he sought treatment at Fox Chase Cancer Center, where he underwent a partial nephrectomy. Unfortunately, the cancer returned six years later, in 2011, and this time both kidneys were affected. During this time, Mike was also having other health complications, including prostate cancer and a left hemispheric stroke that had no residual effects. In 2015, he received a kidney transplant and has been doing well since. "Now, fully recovered, I continue to do part-time business consulting, given my 45 years of business experience, 30 years in the world of franchising, and 15 in senior care/housing," Mike said, adding, "I hope to start volunteering soon at Fox Chase to provide phone counseling for patients who are dealing with cancer. My advice to others is to be the boss; it is your body, and you must be the captain of your ship."

Pages

Research Profile

Research Program

Research Interests

  • Clinical and translational questions involving renal cell carcinoma including decision making models in the management of renal cancers and processes/quality of care in urologic malignancies
  • Analyses of outcomes involving excision, ablation, and active surveillance for localized kidney cancer and techniques/outcomes of surgery in locally advanced and metastatic RCC
  • Actively develop and accrue to multiple industry sponsored national and international urological oncology trials as well as investigator initiated trials.
  • Translational interests include biomarker development in kidney cancer and the role of zinc dyshomeostasis in prostate cancer
Publications

Selected Publications

Chapters and Publications from over 400:

Campbell S.C., Novick A.C., Belldegrun A., Blute M.L., Chow G.K., Derweesh I.H., Faraday M.M., Kaouk J.H., Leveillee R.J., Matin S.F., Russo P., Uzzo R.G., Guideline for Management of the Clinical T1 Renal Mass, 2009, Journal of Urology, 182, 4 SUPPL., 1271, 1279 PubMed

Goel N, Manstein SM, Ward WH, DeMora L, Smaldone MC, Farma JM, Uzzo RG, Esnaola NF. Does the Surgical Apgar Score predict serious complications after elective major cancer surgery? Journal of Surgical Research, 231:242-7, 2018. 

Uzzo R.G., Novick A.C., Nephron sparing surgery for renal tumors: Indications, techniques and outcomes, 2001, Journal of Urology, 166, 1, 6, 18 PubMed

Kutikov A, Uzzo RG. The RENAL Nephrometry Score: A comprehensive standardized system for quantitating renal tumor size, location and depth. J Urol, 182(3):844-53, 2009. (cited 401 times) PubMed

Chawla S.N., Crispen P.L., Hanlon A.L., Greenberg R.E., Chen D.Y.T., Uzzo R.G., The natural history of observed enhancing renal masses: Meta-analysis and review of the world literature, 2006, Journal of Urology, 175, 2, 425, 431 PubMed

Kunkle D.A., Egleston B.L., Uzzo R.G., Excise, Ablate or Observe: The Small Renal Mass Dilemma-A Meta-Analysis and Review, 2008, Journal of Urology, 179, 4, 1227, 1234 PubMed

Kunkle D.A., Uzzo R.G., Cryoablation or radiofrequency ablation of the small renal mass: A meta-analysis, 2008, Cancer, 113, 10, 2671, 2680 PubMed

Uzzo R.G., Wei J.T., Waldbaum R.S., Perlmutter A.P., Byrne J.C., Vaughan Jr. D., The influence of prostate size on cancer detection, 1995, Urology, 46, 6, 831, 836 PubMed

Pollack A., Hanlon A.L., Horwitz E.M., Feigenberg S.J., Konski A.A., Movsas B., Greenberg R.E., Uzzo R.G., Ma C.-M.C., McNeeley S.W., Buyyounouski M.K., Price Jr. R.A., Dosimetry and preliminary acute toxicity in the first 100 men treated for prostate cancer on a randomized hypofractionation dose escalation trial, 2006, International Journal of Radiation Oncology Biology Physics, 64, 2, 518, 526 PubMed

Qiao J., Uzzo R., Obara-Ishihara T., Degenstein L., Fuchs E., Herzlinger D., FGF-7 modulates ureteric bud growth and nephron number in the developing kidney, 1999, Development, 126, 3, 547, 554

Lane B.R., Russo P., Uzzo R.G., Hernandez A.V., Boorjian S.A., Thompson R.H., Fergany A.F., Love T.E., Campbell S.C., Comparison of cold and warm ischemia during partial nephrectomy in 660 solitary kidneys reveals predominant role of nonmodifiable factors in determining ultimate renal function, 2011, Journal of Urology, 185, 2, 421, 427 PubMed

Mann S.J., Pickering T.G., Sos T.A., Uzzo R.G., Sarkar S., Friend K., Rackson M.E., Laragh J.H., Captopril renography in the diagnosis of renal artery stenosis: accuracy and limitations, 1991, The American Journal of Medicine, 90, 1, 30, 40 PubMed

Dulaimi E., Uzzo R.G., Greenberg R.E., Al-Saleem T., Cairns P., Detection of Bladder Cancer in Urine by a Tumor Suppressor Gene Hypermethylation Panel, 2004, Clinical Cancer Research, 10, 6, 1887, 1893 PubMed

Kunkle D.A., Crispen P.L., Chen D.Y.T., Greenberg R.E., Uzzo R.G., Enhancing Renal Masses With Zero Net Growth During Active Surveillance, 2007, Journal of Urology, 177, 3, 849, 854 PubMed

Touijer K., Jacqmin D., Kavoussi L.R., Montorsi F., Patard J.J., Rogers C.G., Russo P., Uzzo R.G., Van Poppel H., The Expanding Role of Partial Nephrectomy: A Critical Analysis of Indications, Results, and Complications, 2010, European Urology, 57, 2, 214, 222 PubMed

Additional Publications

My NCBI

Ratings

190 PATIENT SATISFACTION REVIEWS

Our Patient Satisfaction Rating is an average of all responses to care provider related questions from our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more.

OVERALL RATING

4.9 / 5.0

RATINGS BREAKDOWN

  • 4.9
  • 4.9
  • 4.9
  • 5.0
  • 5.0

49 PATIENT COMMENTS

  • 4.5
    August 30, 2019
    very Satisfiec
  • 5.0
    August 29, 2019
    Could not be happier with Dr Uzzo or the staff, would easily without doubt refer everyone here
  • 5.0
    August 28, 2019
    My wife and I are grateful that Dr Uzzo was willing and able to accept my case and care for me. we could not have and continue to have better care. Dr Uzzo and his office staff and the Fox Chase Cancer Center hospital staff are the best we've encountered. We consider ourselves blessed to be in their care. Thank you all.
  • 5.0
    August 21, 2019
    VERY IMPRESSED WITH THE TIME DR. UZZO SPENT EXPLAINING MY PROBLEM, THE EXTREME DEPTH OF HIS KNOWLEDGE, HIS COMPASSION, HIS SURGICAL SKILLS AND HIS GENUINE CONCERN FOR ME AND MY WELL BEING. HIS STAFF WAS REFLECTED ALL THE SAME QUALITIES
  • 5.0
    July 24, 2019
    My experience with every time I had an appointment with Dr. Robert Uzzo was nothing but outstanding. He spent time explaining my progress with my problem and I only wish every person who is in need of his expertise in the Kidney field could be in his care. Very caring and understanding.
  • 5.0
    July 23, 2019
    great doctor great staff
  • 5.0
    July 18, 2019
    The provider and staff treated me very well.
  • 5.0
    July 18, 2019
    Dr Uzzo and his team are exceptional and Top Notch!!! They are the BEST!!!
  • 5.0
    July 02, 2019
    I could not have been treated any better.
  • 5.0
    June 25, 2019
    Good.
  • 5.0
    June 19, 2019
    I am a cancer survivor thanks to Dr. Uzzo and Fox Chase Cancer. [...]
  • 5.0
    June 16, 2019
    Good experience, as usual.
  • 5.0
    June 12, 2019
    Have been coming to Dr Uzzo for eight years and wouldn't go anywhere else. He takes his time with you and explains everything so you understand what he's talking about. The staff is great also.
  • 5.0
    June 02, 2019
    Dr. Uzzo and his team give top notch care with kindness and compassion. I am very thankful that I am under his care.
  • 5.0
    May 27, 2019
    I believe that Dr. Uzzo & his staff through their professionalism & compassion helped me to be in the very best condition before & after surgery.
  • 5.0
    May 21, 2019
    Dr. Uzzo , Always very concern about how I am doing, he listens and answers the way I can understand him I can not say enough about him... Love this guy
  • 5.0
    May 19, 2019
    Dr. Uzzo & staff are excellent.
  • 5.0
    May 16, 2019
    I have always had a good experience with the dr. and staff.
  • 5.0
    May 12, 2019
    Excellent treatment!
  • 5.0
    April 29, 2019
    Dr Uzzo is a great doctor
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