MENU

Robert G. Uzzo, MD, FACS

Robert Uzzo, MD, FACS

Clinical Locations

Primary Location

Huntingdon Pike
8 Huntingdon Pike
Rockledge, PA

Secondary Location

Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111

About

Chair, Department of Surgical Oncology

G. Willing "Wing" Pepper Chair in Cancer Research

Kidney, Bladder, and Prostate Cancer TRDG Member

Senior Vice-President, Physician Services

President, FCCC Medical Group, Inc.

Professor of Surgery, Temple University Health System

Treatment Focus

  • Robotic and laparoscopic urologic oncology
  • Organ preservation (kidney, bladder, testicular and adrenal)
  • Non-surgical management of low risk urinary tumors
  • Complex urological reconstruction

Research Program

Key Awards

  • Philadelphia Magazine Top Doctors, 2002-2017
  • America’s Top Doctors® 2008-2017
  • Best Doctors in America® 2013-2016

Treatment Philosophy

I believe in treating patients as I would my own family. I strive to communicate effectively with patients and family members at all levels. Through extensive discussions with my patients, I develop treatment plans that are both effective and acknowledge that quality of life issues are exceptionally important. I emphasize individually tailored treatments to help patients achieve success and limit treatment-related side effects which can affect quality of life.

I am sensitive to the particular issues regarding surgical treatment of genitourinary cancer, especially the physical and emotional effects on patients and their family. By fostering a doctor-patient relationship based on mutual respect and open dialogue, I encourage patients to become empowered managers of their care.

... Expand

Follow on Twitter: @FCUroOnc

Chair, Department of Surgical Oncology

Nationally known as a leader in the field of urologic oncology, Dr. Uzzo has made important clinical, scientific and educational contributions to the Department of Surgery.

A fellow of the American College of Surgeons, Uzzo has consistently ranked among Castle Connolly’s and Philadelphia magazine's "Top Docs" in urology. He is a national principal investigator for a clinical trial by the Eastern Cooperative Oncology Group to evaluate new, targeted therapies for kidney cancers and immunotherapy.  He is the author of more than 350 chapters, articles, books and abstracts on urologic tumors and has presented hundreds of regional, national and international lectures.

In addition to his extensive clinical practice, he oversees research laboratory initiatives studying molecular mechanisms of genitourinary cancers. In 2003, he was promoted from Associate Professor to Professor with tenure in Fox Chase's division of medical science.

... Expand

Education, Training & Credentials

Educational Background

  • Fellow, Urologic Oncology, Cleveland Clinic Foundation
  • Fellow, Renal Transplantation and Renovascular Surgery, Cleveland Clinic Foundation
  • Chief Resident, Urology, New York Hospital-Cornell University Medical Center, New York, NY
  • Senior Resident, Urology, Memorial Sloan-Kettering Cancer Center, New York, NY
  • MD, Cornell Medical College, New York, NY, 1991
  • BS/BA, Union College, Schenectady, NY, 1989, Valedictorian

Certifications

  • Diplomate, American Board of Urology

Memberships

  • The American Urological Association
  • Member, American Association of Genitourinary Surgeons, AAGUS
  • Society of Urologic Oncology, Board of Directors
  • Society of Urologic Oncology, Clinical Trials Consortium, President 
  • Society of Urologic Oncology, Clinical Trials Consortium, Renal Program Chairman  
  • Board of Directors, SUO Clinical Trials Consortia, member-at-large  
  • Fox Chase Cancer Center Society of Scholars  
  • Kidney Cancer Association Medical Advisory Board  
  • Fellow American College of Surgeons (F.A.C.S.)  
  • Society of Urologic Oncology  
  • Pennsylvania Medical Society
  • Philadelphia County Medical Society  
  • The MidAtlantic Section of the American Urological Association
  • Eastern Cooperative Oncology Group  
  • Radiation Therapy Oncology Group
  • American College of Surgeons Oncology Group - Vice Chairman, GU Organ Committee   2002-2006 
  • American Society of Transplant Surgeons 
  • Urologic Society of Transplant and Vascular Surgeons
  • Society for Basic Urologic Research  
  • American Association for Cancer Research

Honors & Awards

  • Philadelphia Magazine Top Doctors, 2002-2017
  • America’s Top Doctors® 2008-2017
  • Best Doctors in America® 2013-2016
  • AUA Residents National Committee Teaching Award
  • Consumer’s Research Council of America –America’s Top Physicians 
Patient Stories

John Roley

Kidney Cancer

John Roley

Kidney Cancer

In the fall of 2007, John Roley was shocked to learn he had kidney cancer after experiencing severe stomach pain. After meeting with his doctor, he decided to get a second opinion from Dr. Robert Uzzo, chief of surgical oncology at Fox Chase Cancer Center. Rather than traditional surgery, Dr. Uzzo recommended two surgeries using the minimally-invasive da Vinci robotic surgical procedure that makes tiny incisions, results in very little scarring, and produces almost no bleeding. After the surgeries, John had no complications, healed quickly, and returned to work within weeks. "The doctors and nurses at Fox Chase were simply great in taking care of me and helping me to recover so quickly," he said. "I am forever grateful to everyone who found the problem, fixed the problem, and restored me to excellent health, and I pray that they are able to help others the way they helped me."

Denise Coldwater

Kidney Cancer

Denise Coldwater

Kidney Cancer

Based on my history with cancer, I often feel like the luckiest person on earth. In 1999, at the age of 45, I was diagnosed with kidney cancer. At the time, my only choice was a total nephrectomy (removal of the kidney).

Mike Phillips

Kidney Cancer;  Prostate Cancer

Mike Phillips

Kidney Cancer;  Prostate Cancer

When Mike Phillips was diagnosed with kidney cancer, he sought treatment at Fox Chase Cancer Center, where he underwent a partial nephrectomy. Unfortunately, the cancer returned six years later, in 2011, and this time both kidneys were affected. During this time, Mike was also having other health complications, including prostate cancer and a left hemispheric stroke that had no residual effects. In 2015, he received a kidney transplant and has been doing well since. "Now, fully recovered, I continue to do part-time business consulting, given my 45 years of business experience, 30 years in the world of franchising, and 15 in senior care/housing," Mike said, adding, "I hope to start volunteering soon at Fox Chase to provide phone counseling for patients who are dealing with cancer. My advice to others is to be the boss; it is your body, and you must be the captain of your ship."

Joe Riehs

Kidney Cancer

Joe Riehs

Kidney Cancer

Working high above the Delaware River for the Port Authority is where Joe Riehs spends much of his time. He is a maintenance technician on the Betsy Ross Bridge, connecting Pennsylvania and New Jersey. It was on that bridge that Joe received the call from his doctor with the news. There was an 85% chance that the tumor found on Joe's kidney was cancerous.

Elycia Lerman

Kidney Cancer

Elycia Lerman

Kidney Cancer

Before cancer entered my life, I was working full-time as a director in supply chain, a high-pressure job with international traveling requirements. I’m an industrial engineer by training and worked for 33 years in the health and beauty industry, with the last 25 years in the pharmaceutical industry for Johnson & Johnson. My wife of 22 years and I had a daughter who was eight at the time and a foster son who was 21 and had just been diagnosed with refractory epilepsy.

Pages

Research Profile

Research Program

Research Interests

  • Clinical and translational questions involving renal cell carcinoma including decision making models in the management of renal cancers and processes/quality of care in urologic malignancies
  • Analyses of outcomes involving excision, ablation, and active surveillance for localized kidney cancer and techniques/outcomes of surgery in locally advanced and metastatic RCC
  • Actively develop and accrue to multiple industry sponsored national and international urological oncology trials as well as investigator initiated trials.
  • Translational interests include biomarker development in kidney cancer and the role of zinc dyshomeostasis in prostate cancer
Publications

Selected Publications

Chapters and Publications from over 400:

Campbell S.C., Novick A.C., Belldegrun A., Blute M.L., Chow G.K., Derweesh I.H., Faraday M.M., Kaouk J.H., Leveillee R.J., Matin S.F., Russo P., Uzzo R.G., Guideline for Management of the Clinical T1 Renal Mass, 2009, Journal of Urology, 182, 4 SUPPL., 1271, 1279 PubMed

Uzzo R.G., Novick A.C., Nephron sparing surgery for renal tumors: Indications, techniques and outcomes, 2001, Journal of Urology, 166, 1, 6, 18 PubMed

Kutikov A, Uzzo RG. The RENAL Nephrometry Score: A comprehensive standardized system for quantitating renal tumor size, location and depth. J Urol, 182(3):844-53, 2009. (cited 401 times) PubMed

Chawla S.N., Crispen P.L., Hanlon A.L., Greenberg R.E., Chen D.Y.T., Uzzo R.G., The natural history of observed enhancing renal masses: Meta-analysis and review of the world literature, 2006, Journal of Urology, 175, 2, 425, 431 PubMed

Kunkle D.A., Egleston B.L., Uzzo R.G., Excise, Ablate or Observe: The Small Renal Mass Dilemma-A Meta-Analysis and Review, 2008, Journal of Urology, 179, 4, 1227, 1234 PubMed

Kunkle D.A., Uzzo R.G., Cryoablation or radiofrequency ablation of the small renal mass: A meta-analysis, 2008, Cancer, 113, 10, 2671, 2680 PubMed

Uzzo R.G., Wei J.T., Waldbaum R.S., Perlmutter A.P., Byrne J.C., Vaughan Jr. D., The influence of prostate size on cancer detection, 1995, Urology, 46, 6, 831, 836 PubMed

Pollack A., Hanlon A.L., Horwitz E.M., Feigenberg S.J., Konski A.A., Movsas B., Greenberg R.E., Uzzo R.G., Ma C.-M.C., McNeeley S.W., Buyyounouski M.K., Price Jr. R.A., Dosimetry and preliminary acute toxicity in the first 100 men treated for prostate cancer on a randomized hypofractionation dose escalation trial, 2006, International Journal of Radiation Oncology Biology Physics, 64, 2, 518, 526 PubMed

Qiao J., Uzzo R., Obara-Ishihara T., Degenstein L., Fuchs E., Herzlinger D., FGF-7 modulates ureteric bud growth and nephron number in the developing kidney, 1999, Development, 126, 3, 547, 554

Lane B.R., Russo P., Uzzo R.G., Hernandez A.V., Boorjian S.A., Thompson R.H., Fergany A.F., Love T.E., Campbell S.C., Comparison of cold and warm ischemia during partial nephrectomy in 660 solitary kidneys reveals predominant role of nonmodifiable factors in determining ultimate renal function, 2011, Journal of Urology, 185, 2, 421, 427 PubMed

Mann S.J., Pickering T.G., Sos T.A., Uzzo R.G., Sarkar S., Friend K., Rackson M.E., Laragh J.H., Captopril renography in the diagnosis of renal artery stenosis: accuracy and limitations, 1991, The American Journal of Medicine, 90, 1, 30, 40 PubMed

Dulaimi E., Uzzo R.G., Greenberg R.E., Al-Saleem T., Cairns P., Detection of Bladder Cancer in Urine by a Tumor Suppressor Gene Hypermethylation Panel, 2004, Clinical Cancer Research, 10, 6, 1887, 1893 PubMed

Kunkle D.A., Crispen P.L., Chen D.Y.T., Greenberg R.E., Uzzo R.G., Enhancing Renal Masses With Zero Net Growth During Active Surveillance, 2007, Journal of Urology, 177, 3, 849, 854 PubMed

Touijer K., Jacqmin D., Kavoussi L.R., Montorsi F., Patard J.J., Rogers C.G., Russo P., Uzzo R.G., Van Poppel H., The Expanding Role of Partial Nephrectomy: A Critical Analysis of Indications, Results, and Complications, 2010, European Urology, 57, 2, 214, 222 PubMed

Additional Publications

My NCBI

Write a Review

Review Dr. Uzzo and share your experience with other patients. Your review will help others make informed decisions.

www.foxchase.org/UzzoReview