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Robert G. Uzzo, MD, MBA, FACS

Robert Uzzo, MD, FACS

Clinical Locations

Primary Location

Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111

Secondary Location

Huntingdon Pike
8 Huntingdon Pike
Rockledge, PA

About

Chairman, Department of Surgery

G. Willing "Wing" Pepper Chair in Cancer Research

Professor, Department of Surgery

Professor of Surgery, Temple University Health System

Adjunct Professor of Bioengineering, Temple University College of Engineering

Treatment Focus

  • Robotic and laparoscopic urologic oncology
  • Organ preservation (kidney, bladder, testicular and adrenal)
  • Non-surgical management of low risk urinary tumors
  • Complex urological reconstruction

Research Program

Key Awards

Philadelphia Magazine Top Docs 2021
Urology

Treatment Philosophy

I believe in treating patients as I would my own family. I strive to communicate effectively with patients and family members at all levels. Through extensive discussions with my patients, I develop treatment plans that are both effective and acknowledge that quality of life issues are exceptionally important. I emphasize individually tailored treatments to help patients achieve success and limit treatment-related side effects which can affect quality of life.

I am sensitive to the particular issues regarding surgical treatment of genitourinary cancer, especially the physical and emotional effects on patients and their family. By fostering a doctor-patient relationship based on mutual respect and open dialogue, I encourage patients to become empowered managers of their care... Expand

 

Follow on Twitter: @FCUroOnc

View Dr. Uzzo's PracticeUpdate contributions

Chairman, Department of Surgery

Nationally known as a leader in the field of urologic oncology, Dr. Uzzo has made important clinical, scientific and educational contributions to the Department of Surgery.

A fellow of the American College of Surgeons, Uzzo has consistently ranked among Castle Connolly’s and Philadelphia Magazine's "Top Docs" in urology. He is a national principal investigator for a clinical trial by the Eastern Cooperative Oncology Group to evaluate new, targeted therapies for kidney cancers and immunotherapy.  He is the author of more than 350 chapters, articles, books and abstracts on urologic tumors and has presented hundreds of regional, national and international lectures.

In addition to his extensive clinical practice, he oversees research laboratory initiatives studying molecular mechanisms of genitourinary cancers. In 2003, he was promoted from Associate Professor to Professor with tenure in Fox Chase's division of medical science... Expand

Education and Training

Educational Background

  • Fellow, Urologic Oncology, Cleveland Clinic Foundation
  • Fellow, Renal Transplantation and Renovascular Surgery, Cleveland Clinic Foundation
  • Chief Resident, Urology, New York Hospital-Cornell University Medical Center, New York, NY
  • Senior Resident, Urology, Memorial Sloan-Kettering Cancer Center, New York, NY
  • MD, Cornell Medical College, New York, NY, 1991
  • BS/BA, Union College, Schenectady, NY, 1989, Valedictorian

Certifications

  • Diplomate, American Board of Urology

Memberships

  • The American Urological Association
  • Member, American Association of Genitourinary Surgeons, AAGUS
  • Society of Urologic Oncology, Board of Directors
  • Society of Urologic Oncology, Clinical Trials Consortium, President 
  • Society of Urologic Oncology, Clinical Trials Consortium, Renal Program Chairman  
  • Board of Directors, SUO Clinical Trials Consortia, member-at-large  
  • Fox Chase Cancer Center Society of Scholars  
  • Kidney Cancer Association Medical Advisory Board  
  • Fellow American College of Surgeons (F.A.C.S.)  
  • Society of Urologic Oncology  
  • Pennsylvania Medical Society
  • Philadelphia County Medical Society  
  • The MidAtlantic Section of the American Urological Association
  • Eastern Cooperative Oncology Group  
  • Radiation Therapy Oncology Group
  • American College of Surgeons Oncology Group - Vice Chairman, GU Organ Committee   2002-2006 
  • American Society of Transplant Surgeons 
  • Urologic Society of Transplant and Vascular Surgeons
  • Society for Basic Urologic Research  
  • American Association for Cancer Research

Honors & Awards

  • Philadelphia Magazine Top Doctors, 2002-20
  • Best Doctors in America®, 2013-16, 2019-2020, Urology
  • America’s Top Doctors®, 2008-17
  • AUA Residents National Committee Teaching Award
  • Consumer’s Research Council of America –America’s Top Physicians 
Patient Stories

Tina Pidgeon

Kidney Cancer

Tina Pidgeon

Kidney Cancer

Eleven years ago, I went in for a routine ultrasound to evaluate my pregnancy. I had no idea that the test would completely change my life and lead to a diagnosis of kidney cancer.

David Hiltgen

Kidney Cancer

David Hiltgen

Kidney Cancer

My kidney cancer was discovered at the worst time: right at the start of the COVID-19 pandemic.

Luciano Orsini

Kidney Cancer

Luciano Orsini

Kidney Cancer

I’m 58 years old and live in Sicklerville, New Jersey. In normal times, summer is my favorite time of year. I’d have been looking forward to it this year, if COVID-19 hadn’t happened and forced me to delay my surgery for kidney cancer.

Felix (Phil) Sanchez

Bladder Cancer

Felix (Phil) Sanchez

Bladder Cancer

I follow up with people and act as a mentor. I let them know they are able to contact me at any time, and I can offer them peace of mind from someone who has been where they are headed.

Charlie Smithgall

Kidney Cancer

Charlie Smithgall

Kidney Cancer

"Although cancer is not the news I was expecting to hear, I’m able to see the silver lining in how things worked out the way they did. "

Pages

Research Profile

Research Program

Research Interests

  • Clinical and translational questions involving renal cell carcinoma including decision making models in the management of renal cancers and processes/quality of care in urologic malignancies
  • Analyses of outcomes involving excision, ablation, and active surveillance for localized kidney cancer and techniques/outcomes of surgery in locally advanced and metastatic RCC
  • Actively develop and accrue to multiple industry sponsored national and international urological oncology trials as well as investigator initiated trials.
  • Translational interests include biomarker development in kidney cancer and the role of zinc dyshomeostasis in prostate cancer
Publications

Selected Publications

Chapters and Publications from over 400:

Campbell S.C., Novick A.C., Belldegrun A., Blute M.L., Chow G.K., Derweesh I.H., Faraday M.M., Kaouk J.H., Leveillee R.J., Matin S.F., Russo P., Uzzo R.G., Guideline for Management of the Clinical T1 Renal Mass, 2009, Journal of Urology, 182, 4 SUPPL., 1271, 1279 PubMed

Goel N, Manstein SM, Ward WH, DeMora L, Smaldone MC, Farma JM, Uzzo RG, Esnaola NF. Does the Surgical Apgar Score predict serious complications after elective major cancer surgery? Journal of Surgical Research, 231:242-7, 2018. 

Uzzo R.G., Novick A.C., Nephron sparing surgery for renal tumors: Indications, techniques and outcomes, 2001, Journal of Urology, 166, 1, 6, 18 PubMed

Kutikov A, Uzzo RG. The RENAL Nephrometry Score: A comprehensive standardized system for quantitating renal tumor size, location and depth. J Urol, 182(3):844-53, 2009. (cited 401 times) PubMed

Chawla S.N., Crispen P.L., Hanlon A.L., Greenberg R.E., Chen D.Y.T., Uzzo R.G., The natural history of observed enhancing renal masses: Meta-analysis and review of the world literature, 2006, Journal of Urology, 175, 2, 425, 431 PubMed

Kunkle D.A., Egleston B.L., Uzzo R.G., Excise, Ablate or Observe: The Small Renal Mass Dilemma-A Meta-Analysis and Review, 2008, Journal of Urology, 179, 4, 1227, 1234 PubMed

Kunkle D.A., Uzzo R.G., Cryoablation or radiofrequency ablation of the small renal mass: A meta-analysis, 2008, Cancer, 113, 10, 2671, 2680 PubMed

Uzzo R.G., Wei J.T., Waldbaum R.S., Perlmutter A.P., Byrne J.C., Vaughan Jr. D., The influence of prostate size on cancer detection, 1995, Urology, 46, 6, 831, 836 PubMed

Pollack A., Hanlon A.L., Horwitz E.M., Feigenberg S.J., Konski A.A., Movsas B., Greenberg R.E., Uzzo R.G., Ma C.-M.C., McNeeley S.W., Buyyounouski M.K., Price Jr. R.A., Dosimetry and preliminary acute toxicity in the first 100 men treated for prostate cancer on a randomized hypofractionation dose escalation trial, 2006, International Journal of Radiation Oncology Biology Physics, 64, 2, 518, 526 PubMed

Qiao J., Uzzo R., Obara-Ishihara T., Degenstein L., Fuchs E., Herzlinger D., FGF-7 modulates ureteric bud growth and nephron number in the developing kidney, 1999, Development, 126, 3, 547, 554

Lane B.R., Russo P., Uzzo R.G., Hernandez A.V., Boorjian S.A., Thompson R.H., Fergany A.F., Love T.E., Campbell S.C., Comparison of cold and warm ischemia during partial nephrectomy in 660 solitary kidneys reveals predominant role of nonmodifiable factors in determining ultimate renal function, 2011, Journal of Urology, 185, 2, 421, 427 PubMed

Mann S.J., Pickering T.G., Sos T.A., Uzzo R.G., Sarkar S., Friend K., Rackson M.E., Laragh J.H., Captopril renography in the diagnosis of renal artery stenosis: accuracy and limitations, 1991, The American Journal of Medicine, 90, 1, 30, 40 PubMed

Dulaimi E., Uzzo R.G., Greenberg R.E., Al-Saleem T., Cairns P., Detection of Bladder Cancer in Urine by a Tumor Suppressor Gene Hypermethylation Panel, 2004, Clinical Cancer Research, 10, 6, 1887, 1893 PubMed

Kunkle D.A., Crispen P.L., Chen D.Y.T., Greenberg R.E., Uzzo R.G., Enhancing Renal Masses With Zero Net Growth During Active Surveillance, 2007, Journal of Urology, 177, 3, 849, 854 PubMed

Touijer K., Jacqmin D., Kavoussi L.R., Montorsi F., Patard J.J., Rogers C.G., Russo P., Uzzo R.G., Van Poppel H., The Expanding Role of Partial Nephrectomy: A Critical Analysis of Indications, Results, and Complications, 2010, European Urology, 57, 2, 214, 222 PubMed

Additional Publications

My NCBI

Ratings

352 PATIENT SATISFACTION REVIEWS

Our Patient Satisfaction Rating is an average of all responses to care provider related questions from our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more.

OVERALL RATING

5.0 / 5.0

RATINGS BREAKDOWN

  • 5.0
  • 5.0
  • 5.0
  • 5.0
  • 4.9

93 PATIENT COMMENTS

  • 5.0
    April 27, 2021
    Excellent care & service. 5 stars to doctor, nurse & staff.
  • 5.0
    April 23, 2021
    Keep it as great as it is. I think it is the best. I'm very happy to be associated with Dr. Uzzo, the professional staff, and all members of Fox Chase. Thank you very much. [...]
  • No Star Ratings Available April 23, 2021
    Broke down the diagnosis as well as options very well
  • 5.0
    April 16, 2021
    Good experience
  • 5.0
    April 16, 2021
    Thank you for the opinion as to what we need to do.
  • No Star Ratings Available April 06, 2021
    Provided input on another issue found during the ultra sound and sent information to my family and specialist doctors.
  • No Star Ratings Available April 04, 2021
    Very friendly and answered all questions. A+ doctor.
  • 5.0
    April 02, 2021
    Efficient, prompt, caring and compassionate care
  • 5.0
    March 20, 2021
    Great Dr. Great staff
  • No Star Ratings Available March 17, 2021
    Dr Uzzo is patient, knowledgeable, and takes the time to ensure you are getting the best care possible.
  • No Star Ratings Available March 17, 2021
    excellent experience
  • 5.0
    March 08, 2021
    Doctor Uzzo and his staff have consistently been professional. Courteous, friendly & caring. He is my opinion, easily the best urologist on the East Coast.
  • 4.5
    March 07, 2021
    Very good experience
  • 5.0
    March 03, 2021
    Dr. Uzzo and the staff made me feel at ease during the visit. My anxiety was lessened. Everything was explained to me in terms that I could understand.
  • 5.0
    February 25, 2021
    Dr. Uzzo & his nurse [...] are great. Also his office staff are kind, thorough, efficient, etc.
  • 5.0
    February 19, 2021
    Dr. Uzzo knows how to deal with his patients . He knows that we worry and are stressed out waiting for the results and he is direct, to the point, gives you the info right away to relieve your stress right away. Then he proceeds with what he has to do. His patients come first. In regard to r ating Dr. Uzzo. You need to go higher than 10 to be ccurte.
  • 5.0
    February 19, 2021
    great, safe
  • 5.0
    January 30, 2021
    Doctor Uzzo is amazing I don't think I'd be alive if it weren't for him I'm grateful for his work ethic an pride he takes in his craft because I've seen doctors just tell you things to get you out of there but Doctor Uzzo treats every patient like as if they were his own family members I was very lucky
  • 5.0
    January 29, 2021
    I was treated as expected. Each time I had an appointment I was treated with respect,
  • 4.5
    January 26, 2021
    Have seen Dr. Uzzo many times as a surgical inpatient and outpatient. Am completely satisfied with the care provided by him and his team.
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