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Jeffrey Chang-Jen Liu, MD, FACS
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- Clinical Locations
- About
- Education and Training
- Research Profile
- Publications
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Clinical Locations
Primary Location
Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111
About
Attending Surgeon
Associate Professor, Department of Surgical Oncology
Medical Director, Speech Pathology
Associate Professor, Department of Otolaryngology
Specialties
Treatment Focus
Head and neck cancer, including cancers of the tongue, throat, voice box. Thyroid cancer, skin cancer.
Research Program
Key Awards
Otolaryngology
Treatment Philosophy
I am committed to developing a coordinated, personalized plan appropriate for the treatment of your head and neck cancer. This will often be done in coordination with other physicians and staff from other specialties, including radiation therapists, medical oncologists, dentists and prosthodontists, plastic and reconstructive surgeons, pathologists, neuroradiologists, oncology social workers, oncology nutritionists and speech/swallow specialists.
Our Head and Neck Multidisciplinary Tumor Board at Fox Chase Cancer Center offers an opportunity to coordinate all facets of your care to execute a unique treatment plan tailored to give you the best chance of curing your cancer while maintaining function.
Follow on Twitter: @FCCCSurgOnc
Education and Training
Educational Background
- Fellow, Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, 2010
- Resident, Otolaryngology, New York Presbyterian Hospital, Columbia and Cornell Campuses, New York, NY, 2008
- MD, with Honors in Research, Weill Medical College, Cornell University, New York, NY, 2003
Certifications
- American Board of Otolaryngology/Head and Neck Surgery
Memberships
- American College of Surgeons
- American Head and Neck Society
- American Academy of Otolaryngology
Honors & Awards
- Philadelphia Magazine Top Doctors, 2018-20
- Resident Leadership Grant Recipient, American Academy of Otolaryngology, 2007-11
- National Institute of Health T32 Training Grant Recipient (CA09685), Memorial Sloan Kettering Cancer Center, 2008
- 1st Place, 6th Annual Resident Research Competition, Columbia/Cornell Otolaryngology, 2006
Research Profile
Research Program
Research Interests
- Translational research evaluating genetics and molecular profiles in head and neck cancer outcomes
- Racial disparities in head and neck cancer incidence and treatment
Publications
Selected Publications
Treatment and Outcomes of Oropharyngeal Cancer in People with Human Immunodeficiency Virus. AIDS Res Hum Retroviruses. 2019 Aug 29;. doi: 10.1089/AID.2019.0009. [Epub ahead of print] PubMed PMID: 31347379.
Common Pitfalls of Head and Neck Research Using Cancer Registries. Otolaryngol Head Neck Surg. 2019 Aug;161(2):245-250. doi: 10.1177/0194599819838823. Epub 2019 Apr 2. PubMed PMID: 30939098.
Examining adjuvant radiation dose in head and neck squamous cell carcinoma. Head Neck. 2019 Jul;41(7):2133-2142. doi: 10.1002/hed.25680. Epub 2019 Feb 9. PubMed PMID: 30737968.
The impact of the multidisciplinary tumor board on head and neck cancer outcomes. Laryngoscope. 2019 May 16;. doi: 10.1002/lary.28066. [Epub ahead of print] PubMed PMID: 31095740.
Patterns of distant metastasis in head and neck cancer at presentation: Implications for initial evaluation. Oral Oncol. 2019 Jan;88:131-136. doi: 10.1016/j.oraloncology.2018.11.023. Epub 2018 Nov 27. PubMed PMID: 30616783.
Lee Z, Waldorf BT, Cho EY, Liu JC, Metro MJ, Eun DD. Robotic Ureteroplasty with Buccal Mucosa Graft for the Management of Complex Ureteral Strictures. The Journal of urology. 2017; 198(6):1430-1435.
Wang LS, Handorf EA, Wu H, Liu JC, Perlis CS, Galloway TJ. Surgery and Adjuvant Radiation for High-risk Skin Adnexal Carcinoma of the Head and Neck. American journal of clinical oncology. 2017; 40(4):429-432. NIHMSID: NIHMS648261
Ramakodi MP, Devarajan K, Blackman E, Gibbs D, Luce D, Deloumeaux J, Duflo S, Liu JC, Mehra R, Kulathinal RJ, Ragin CC. Integrative genomic analysis identifies ancestry-related expression quantitative trait loci on DNA polymerase β and supports the association of genetic ancestry with survival disparities in head and neck squamous cell carcinoma. Cancer. 2017; 123(5):849-860. NIHMSID: NIHMS827555
Liederbach E, Kyrillos A, Wang CH, Liu JC, Sturgis EM, Bhayani MK. The national landscape of human papillomavirus-associated oropharynx squamous cell carcinoma. International journal of cancer. 2017; 140(3):504-512.
Ragin C, Liu JC, Jones G, Shoyele O, Sowunmi B, Kennett R, Groen HJ, Gibbs D, Blackman E, Esan M, Brandwein MS, Devarajan K, Bussu F, Chernock R, Chien CY, Cohen MA, Samir EM, Mikio S, D'Souza G, Funchain P, Eng C, Gollin SM, Hong A, Jung YS, Krüger M, Lewis J Jr, Morbini P, Landolfo S, Rittà M, Straetmans J, Szarka K, Tachezy R, Worden FP, Nelson D, Gathere S, Taioli E. Prevalence of HPV Infection in Racial-Ethnic Subgroups of Head and Neck Cancer Patients. Carcinogenesis. 2016;
Koshkareva Y, Liu JC, Lango M, Galloway T, Gaughan JP, Ridge JA. Cervical metastasis in squamous cell carcinoma of the hard palate and maxillary alveolus. Ear, nose, & throat journal. 2016; 95(10-11):E6-E11.
Lango MN, Galloway TJ, Mehra R, Ebersole B, Liu JC, Moran K, Ridge JA. Impact of baseline patient reported dysphagia on acute gastrostomy placement in patients with head and neck squamous cell carcinoma undergoing definitive radiation. Head & neck. 2016; 38 Suppl 1:E1318-24.
Liu JC, Parajuli S, Blackman E, Gibbs D, Ellis A, Hull A, Beck JR, Giri V, Iherjirka P, Khurana JS, Ragin CR. High prevalence of discordant human papillomavirus and p16 oropharyngeal squamous cell carcinomas in an African American cohort. Head & neck. 2016; 38 Suppl 1:E867-72. NIHMSID: NIHMS724207
Fu W, Sun J, Huang G, Liu JC, Kaufman A, Ryan RJ, Ramanathan SY, Venkatesh T, Singh B. Squamous Cell Carcinoma-related Oncogene (SCCRO) Family Members Regulate Cell Growth and Proliferation through Their Cooperative and Antagonistic Effects on Cullin Neddylation. The Journal of biological chemistry. 2016; 291(12):6200-17.
Ramakodi MP, Kulathinal RJ, Chung Y, Serebriiskii I, Liu JC, Ragin CC. Ancestral-derived effects on the mutational landscape of laryngeal cancer. Genomics. 2016; 107(2-3):76-82. NIHMSID: NIHMS750683
Additional Publications
Clinical Locations
Primary Location
Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111
Attending Surgeon
Associate Professor, Department of Surgical Oncology
Medical Director, Speech Pathology
Associate Professor, Department of Otolaryngology
Specialties
Treatment Focus
Head and neck cancer, including cancers of the tongue, throat, voice box. Thyroid cancer, skin cancer.
Research Program
Key Awards
Otolaryngology
Treatment Philosophy
I am committed to developing a coordinated, personalized plan appropriate for the treatment of your head and neck cancer. This will often be done in coordination with other physicians and staff from other specialties, including radiation therapists, medical oncologists, dentists and prosthodontists, plastic and reconstructive surgeons, pathologists, neuroradiologists, oncology social workers, oncology nutritionists and speech/swallow specialists.
Our Head and Neck Multidisciplinary Tumor Board at Fox Chase Cancer Center offers an opportunity to coordinate all facets of your care to execute a unique treatment plan tailored to give you the best chance of curing your cancer while maintaining function.
Follow on Twitter: @FCCCSurgOnc
Education
Educational Background
- Fellow, Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, 2010
- Resident, Otolaryngology, New York Presbyterian Hospital, Columbia and Cornell Campuses, New York, NY, 2008
- MD, with Honors in Research, Weill Medical College, Cornell University, New York, NY, 2003
Certifications
- American Board of Otolaryngology/Head and Neck Surgery
Memberships
- American College of Surgeons
- American Head and Neck Society
- American Academy of Otolaryngology
Honors & Awards
- Philadelphia Magazine Top Doctors, 2018-20
- Resident Leadership Grant Recipient, American Academy of Otolaryngology, 2007-11
- National Institute of Health T32 Training Grant Recipient (CA09685), Memorial Sloan Kettering Cancer Center, 2008
- 1st Place, 6th Annual Resident Research Competition, Columbia/Cornell Otolaryngology, 2006
Research Profile
Research Interests
- Translational research evaluating genetics and molecular profiles in head and neck cancer outcomes
- Racial disparities in head and neck cancer incidence and treatment
Publications
Selected Publications
Treatment and Outcomes of Oropharyngeal Cancer in People with Human Immunodeficiency Virus. AIDS Res Hum Retroviruses. 2019 Aug 29;. doi: 10.1089/AID.2019.0009. [Epub ahead of print] PubMed PMID: 31347379.
Common Pitfalls of Head and Neck Research Using Cancer Registries. Otolaryngol Head Neck Surg. 2019 Aug;161(2):245-250. doi: 10.1177/0194599819838823. Epub 2019 Apr 2. PubMed PMID: 30939098.
Examining adjuvant radiation dose in head and neck squamous cell carcinoma. Head Neck. 2019 Jul;41(7):2133-2142. doi: 10.1002/hed.25680. Epub 2019 Feb 9. PubMed PMID: 30737968.
The impact of the multidisciplinary tumor board on head and neck cancer outcomes. Laryngoscope. 2019 May 16;. doi: 10.1002/lary.28066. [Epub ahead of print] PubMed PMID: 31095740.
Patterns of distant metastasis in head and neck cancer at presentation: Implications for initial evaluation. Oral Oncol. 2019 Jan;88:131-136. doi: 10.1016/j.oraloncology.2018.11.023. Epub 2018 Nov 27. PubMed PMID: 30616783.
Lee Z, Waldorf BT, Cho EY, Liu JC, Metro MJ, Eun DD. Robotic Ureteroplasty with Buccal Mucosa Graft for the Management of Complex Ureteral Strictures. The Journal of urology. 2017; 198(6):1430-1435.
Wang LS, Handorf EA, Wu H, Liu JC, Perlis CS, Galloway TJ. Surgery and Adjuvant Radiation for High-risk Skin Adnexal Carcinoma of the Head and Neck. American journal of clinical oncology. 2017; 40(4):429-432. NIHMSID: NIHMS648261
Ramakodi MP, Devarajan K, Blackman E, Gibbs D, Luce D, Deloumeaux J, Duflo S, Liu JC, Mehra R, Kulathinal RJ, Ragin CC. Integrative genomic analysis identifies ancestry-related expression quantitative trait loci on DNA polymerase β and supports the association of genetic ancestry with survival disparities in head and neck squamous cell carcinoma. Cancer. 2017; 123(5):849-860. NIHMSID: NIHMS827555
Liederbach E, Kyrillos A, Wang CH, Liu JC, Sturgis EM, Bhayani MK. The national landscape of human papillomavirus-associated oropharynx squamous cell carcinoma. International journal of cancer. 2017; 140(3):504-512.
Ragin C, Liu JC, Jones G, Shoyele O, Sowunmi B, Kennett R, Groen HJ, Gibbs D, Blackman E, Esan M, Brandwein MS, Devarajan K, Bussu F, Chernock R, Chien CY, Cohen MA, Samir EM, Mikio S, D'Souza G, Funchain P, Eng C, Gollin SM, Hong A, Jung YS, Krüger M, Lewis J Jr, Morbini P, Landolfo S, Rittà M, Straetmans J, Szarka K, Tachezy R, Worden FP, Nelson D, Gathere S, Taioli E. Prevalence of HPV Infection in Racial-Ethnic Subgroups of Head and Neck Cancer Patients. Carcinogenesis. 2016;
Koshkareva Y, Liu JC, Lango M, Galloway T, Gaughan JP, Ridge JA. Cervical metastasis in squamous cell carcinoma of the hard palate and maxillary alveolus. Ear, nose, & throat journal. 2016; 95(10-11):E6-E11.
Lango MN, Galloway TJ, Mehra R, Ebersole B, Liu JC, Moran K, Ridge JA. Impact of baseline patient reported dysphagia on acute gastrostomy placement in patients with head and neck squamous cell carcinoma undergoing definitive radiation. Head & neck. 2016; 38 Suppl 1:E1318-24.
Liu JC, Parajuli S, Blackman E, Gibbs D, Ellis A, Hull A, Beck JR, Giri V, Iherjirka P, Khurana JS, Ragin CR. High prevalence of discordant human papillomavirus and p16 oropharyngeal squamous cell carcinomas in an African American cohort. Head & neck. 2016; 38 Suppl 1:E867-72. NIHMSID: NIHMS724207
Fu W, Sun J, Huang G, Liu JC, Kaufman A, Ryan RJ, Ramanathan SY, Venkatesh T, Singh B. Squamous Cell Carcinoma-related Oncogene (SCCRO) Family Members Regulate Cell Growth and Proliferation through Their Cooperative and Antagonistic Effects on Cullin Neddylation. The Journal of biological chemistry. 2016; 291(12):6200-17.
Ramakodi MP, Kulathinal RJ, Chung Y, Serebriiskii I, Liu JC, Ragin CC. Ancestral-derived effects on the mutational landscape of laryngeal cancer. Genomics. 2016; 107(2-3):76-82. NIHMSID: NIHMS750683
Additional Publications
Related Articles
41 PATIENT COMMENTS
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5.0
January 29, 2021
I see commercials about fox chase on television and I agree, best hospital for cancer treatment. My doctor is the best. He listens and cares about your condition.
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5.0
January 02, 2021
Very good.
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5.0
December 19, 2020
Keep up the great work! Merry Christmas!
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4.5
November 30, 2020
Visit was due to surgery. Doctor & staff excellent.
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3.0
November 02, 2020
[...] Felt rushed by MD - would like my time to be equally respected. Answers to my questions brief.
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5.0
November 01, 2020
[...] exemplary.
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5.0
October 28, 2020
Loved the ENT team! Thank you Dr. Liu!
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5.0
July 31, 2020
Dr. Liu was very understanding and sincere. He answered all my questions without hesitation.
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4.5
July 31, 2020
Dr. Liu has demonstrated a positive willingness to work with others on this [...] carcinoma. [...]
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5.0
July 31, 2020
Doctor Liu and internist Doctor [...] very professional. Excellent bedside manner.
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4.7
July 13, 2020
It was a good experience. Dr. Liu eased my concerns and answered all my questions.
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5.0
July 07, 2020
All was very good.
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5.0
June 28, 2020
great experience!
-
5.0
June 26, 2020
Dr. Liu is caring, kind, personable and smart. couldn't be happier with my new doctor [...].
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5.0
June 25, 2020
Very good relationship with Dr. Liu.
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5.0
June 02, 2020
Dr. Lou is a fantastic Doctor
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5.0
June 02, 2020
Dr.Liu was very professional and his treatment of my cancer is appreciated.
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5.0
May 31, 2020
[...] great doctor - great guy!
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5.0
May 27, 2020
This was my first appt. with Dr. Liu. He made me feel very comfortable & confident in his ability to do my surgery & follow up.
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5.0
May 25, 2020
Dr. Liu is rather new to me. He is an excellent doctor. Caring.
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