Jeffrey Chang-Jen Liu, MD, FACS

Jeffrey Chang-Jen Liu, MD

Clinical Locations

Primary Location

Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111


Attending Surgeon

Associate Professor, Department of Surgical Oncology

Medical Director, Speech Pathology

Associate Professor, Department of Otolaryngology

Head and Neck Cancer TRDG Member

Thyroid and Endocrine Cancer TRDG Member

Treatment Focus

Head and neck cancer, including cancers of the tongue, throat, voice box. Thyroid cancer, skin cancer.

Key Awards

Philadelphia Magazine Top Docs 2019

Treatment Philosophy

I am committed to developing a coordinated, personalized plan appropriate for the treatment of your head and neck cancer. This will often be done in coordination with other physicians and staff from other specialties, including radiation therapists, medical oncologists, dentists and prosthodontists, plastic and reconstructive surgeons, pathologists, neuroradiologists, oncology social workers, oncology nutritionists and speech/swallow specialists.

Our Head and Neck Multidisciplinary Tumor Board at Fox Chase Cancer Center offers an opportunity to coordinate all facets of your care to execute a unique treatment plan tailored to give you the best chance of curing your cancer while maintaining function.

Follow on Twitter: @FCCCSurgOnc

Education and Training

Educational Background

  • Fellow, Head and Neck Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, 2010
  • Resident, Otolaryngology, New York Presbyterian Hospital, Columbia and Cornell Campuses, New York, NY, 2008
  • MD, with Honors in Research, Weill Medical College, Cornell University, New York, NY, 2003


  • American Board of Otolaryngology/Head and Neck Surgery


  • American College of Surgeons
  • American Head and Neck Society
  • American Academy of Otolaryngology

Honors & Awards

  • Philadelphia Magazine Top Doctors, 2018, 2019
  • Resident Leadership Grant Recipient, American Academy of Otolaryngology, 2007-11
  • National Institute of Health T32 Training Grant Recipient (CA09685), Memorial Sloan Kettering Cancer Center, 2008
  • 1st Place, 6th Annual Resident Research Competition, Columbia/Cornell Otolaryngology, 2006
Research Profile

Research Interests

  • Translational research evaluating genetics and molecular profiles in head and neck cancer outcomes
  • Racial disparities in head and neck cancer incidence and treatment

Selected Publications

Full list of publications

Lee Z, Waldorf BT, Cho EY, Liu JC, Metro MJ, Eun DD. Robotic Ureteroplasty with Buccal Mucosa Graft for the Management of Complex Ureteral Strictures. The Journal of urology. 2017; 198(6):1430-1435.

Wang LS, Handorf EA, Wu H, Liu JC, Perlis CS, Galloway TJ. Surgery and Adjuvant Radiation for High-risk Skin Adnexal Carcinoma of the Head and Neck. American journal of clinical oncology. 2017; 40(4):429-432. NIHMSID: NIHMS648261

Ramakodi MP, Devarajan K, Blackman E, Gibbs D, Luce D, Deloumeaux J, Duflo S, Liu JC, Mehra R, Kulathinal RJ, Ragin CC. Integrative genomic analysis identifies ancestry-related expression quantitative trait loci on DNA polymerase β and supports the association of genetic ancestry with survival disparities in head and neck squamous cell carcinoma. Cancer. 2017; 123(5):849-860. NIHMSID: NIHMS827555

 Liederbach E, Kyrillos A, Wang CH, Liu JC, Sturgis EM, Bhayani MK. The national landscape of human papillomavirus-associated oropharynx squamous cell carcinoma. International journal of cancer. 2017; 140(3):504-512.

Ragin C, Liu JC, Jones G, Shoyele O, Sowunmi B, Kennett R, Groen HJ, Gibbs D, Blackman E, Esan M, Brandwein MS, Devarajan K, Bussu F, Chernock R, Chien CY, Cohen MA, Samir EM, Mikio S, D'Souza G, Funchain P, Eng C, Gollin SM, Hong A, Jung YS, Krüger M, Lewis J Jr, Morbini P, Landolfo S, Rittà M, Straetmans J, Szarka K, Tachezy R, Worden FP, Nelson D, Gathere S, Taioli E. Prevalence of HPV Infection in Racial-Ethnic Subgroups of Head and Neck Cancer Patients. Carcinogenesis. 2016;

Koshkareva Y, Liu JC, Lango M, Galloway T, Gaughan JP, Ridge JA. Cervical metastasis in squamous cell carcinoma of the hard palate and maxillary alveolus. Ear, nose, & throat journal. 2016; 95(10-11):E6-E11.

Lango MN, Galloway TJ, Mehra R, Ebersole B, Liu JC, Moran K, Ridge JA. Impact of baseline patient reported dysphagia on acute gastrostomy placement in patients with head and neck squamous cell carcinoma undergoing definitive radiation. Head & neck. 2016; 38 Suppl 1:E1318-24.

Liu JC, Parajuli S, Blackman E, Gibbs D, Ellis A, Hull A, Beck JR, Giri V, Iherjirka P, Khurana JS, Ragin CR. High prevalence of discordant human papillomavirus and p16 oropharyngeal squamous cell carcinomas in an African American cohort. Head & neck. 2016; 38 Suppl 1:E867-72. NIHMSID: NIHMS724207

Fu W, Sun J, Huang G, Liu JC, Kaufman A, Ryan RJ, Ramanathan SY, Venkatesh T, Singh B. Squamous Cell Carcinoma-related Oncogene (SCCRO) Family Members Regulate Cell Growth and Proliferation through Their Cooperative and Antagonistic Effects on Cullin Neddylation. The Journal of biological chemistry. 2016; 291(12):6200-17.

Ramakodi MP, Kulathinal RJ, Chung Y, Serebriiskii I, Liu JC, Ragin CC. Ancestral-derived effects on the mutational landscape of laryngeal cancer. Genomics. 2016; 107(2-3):76-82. NIHMSID: NIHMS750683



Our Patient Satisfaction Rating is an average of all responses to care provider related questions from our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more.


4.9 / 5.0


  • 5.0
  • 4.9
  • 5.0
  • 5.0
  • 4.8


  • 5.0
    June 27, 2019
    very helpful with this visit.
  • 5.0
    June 13, 2019
    Satisfied patient.
  • 5.0
    May 28, 2019
    Dr. Liu was very knowledgeable, thorough and understaning. I definitely want him to perform my surgery.
  • 5.0
    May 27, 2019
    Dr. Liu is a great doctor and a good man.
  • 5.0
    May 08, 2019
    Dr. Liu, Dr. [...], & the entire H&N team has been so wonderful through all of this!
  • 5.0
    May 06, 2019
    Dr. Liu is exceptional.
  • 5.0
    April 28, 2019
    I have always had an excellent experience.
  • 5.0
    March 25, 2019
    Fox Chase & Dr. Lui & Dr. [...] are top quality dr.
  • 5.0
    March 16, 2019
    I will never go anywhere else except to Dr. Liu & to Fox Chase. This doctor and this hospital treated me like I was a valued person and patient.
  • 5.0
    March 11, 2019
    every thing was excellant
  • 5.0
    February 17, 2019
    Dr. Liu and his team put us at ease and did an excellent job at providing care and sensitivity. #1!
  • 4.4
    February 12, 2019
    Didn't feel check up was thorough enough (first time).
  • 5.0
    January 26, 2019
    This was my first appointment with Dr. Liu and it went very well.
  • 5.0
    January 26, 2019
    Dr. Jeffrey Lui is an awesome person.
  • 5.0
    January 26, 2019
    dr lui goes above and beyond my expectations, one of the best doctors I've ever had.
  • 5.0
    January 21, 2019
    Dr Lui is a great doctor and I have decided to make him my primary ENT. Excellent care was received and I highly recommend him
  • 5.0
    November 18, 2018
    Always excellent.
  • 5.0
    November 15, 2018
  • 5.0
    November 07, 2018
    Dr. Liu is always helpful with a positive attitude.
  • 5.0
    October 31, 2018

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