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Marc C. Smaldone, MD, MSHP, FACS

Marc Smaldone, MD, MSHP

Clinical Locations

Primary Location

Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111

About

Associate Professor, Department of Surgical Oncology

Kidney, Bladder, and Prostate Cancer TRDG Member

NCCN, Prostate Cancer Early Detection Panel Member

Treatment Focus

  • Robotic and laparoscopic minimally invasive surgery
  • Continent urinary diversion
  • Salvage and reconstructive Surgery

Research Program

Treatment Philosophy

I am a urologic oncologist specializing in the surgical management of tumors of the kidney, bladder, prostate, adrenal, testis and other genitourinary organs. As part of the multi-disciplinary Genitourinary Cancer Patient Care Team, I work closely with my colleagues in Medical and Radiation Oncology to develop a comprehensive treatment plan that offers the best chance for cure for each patient.

The mission at the Fox Chase Cancer Center is to deliver world class oncologic care in the most compassionate and respectful way possible. A cancer diagnosis brings fear and uncertainty for patients and their families, and my personal philosophy is to treat patients how I would wish for my family members to be treated. Patient education is essential, and I consider it of utmost importance to take the time necessary for patients to understand and feel comfortable with all possible treatment options to inspire confident decision making.

I have expertise in open, laparoscopic, and robotic surgical techniques, which allows me to tailor a specific treatment plan based on individual patient need and preferences. I have particular expertise in minimally invasive organ preserving and reconstructive techniques to preserve function and quality of life, including nerve-sparing prostatectomy for patients with prostate cancer and partial nephrectomy for patients with kidney cancer. I have experience performing both robotic and open cystectomy for patients with bladder cancer, and prefer to construct continent urinary diversions whenever possible. I have a clinical interest in the surgical management of patients with high risk and advanced disease, and have experience performing retroperitoneal lymph node dissection following chemotherapy in patients with testicular cancer, cytoreductive nephrectomy and thrombectomy for patients with metastatic kidney cancer or tumors extending into the vena cava, and salvage surgery following radiation for patients with bladder or prostate cancer.

Follow on Twitter: @FCUroOnc

Education and Training

Educational Background

  • Fellowship: Urologic Oncology, Fox Chase Cancer Center, Philadelphia, PA
  • Residency: Urologic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA
  • MS, Health Policy Research, University of Pennsylvania, Philadelphia, PA
  • MD, State University of New York at Stony Brook School of Medicine, Stony Brook, NY

Certifications

  • American Board of Urology

Memberships

  • National Comprehensive Cancer Network (NCCN)
    • Prostate Cancer Early Detection Panel
  • American Urological Association
  • Society of Urologic Oncology

Honors & Awards

  • Main Line Today Top Doctors, 2018-2019
Patient Stories

William O'Brien

Bladder Cancer

William O'Brien

Bladder Cancer

In 2015, Bill O’Brien and his wife, Jackie, celebrated 51 years of marriage. Spending time with friends is very important to them. During a weekly “breakfast club” outing in 2012 – where they meet a group of friends at a local restaurant for breakfast, Bill felt something wasn’t right with him. “I went to the rest room and I started experiencing urinary bleeding," recalls Bill, who realized he needed to see a urologist as soon as possible. Following an exam and testing, the urologist told him that something was detected on his bladder.

Marcille McEntee

Skin Cancer;  Ureteral Cancer

Marcille McEntee

Skin Cancer;  Ureteral Cancer

Her gastroenterologist performed a PET scan which revealed a rare kind of cancer, a mucosal melanoma. “At that point, my urologist admitted 'this is beyond me. You need to go somewhere else',” she recalled.

Joseph Dequinque

Bladder Cancer;  Colorectal Cancer;  Kidney Cancer

Joseph Dequinque

Bladder Cancer;  Colorectal Cancer;  Kidney Cancer

South Philadelphia resident Joseph DeQuinque tries to maintain a healthy lifestyle.  He’s a non-smoker, watches his diet and takes frequent walks with his wife Laura, with whom he celebrated his 55th wedding anniversary in 2014.

In July, 2013, at the age of 79, he noticed blood in his urine and made an immediate appointment with his urologist. After various tests, including a CAT scan, Joseph learned he had cancer in both his bladder and kidney, which is unusual.

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Research Profile

Research Program

Research Interests

  • Quality of care
  • Comparative effectiveness
  • Risk assessment
  • Access disparities
  • Surgical outcomes
  • Health services research
Publications

Selected Publications

Correa AF, Handorf E, Joshi SS, Geynisman DM, Kutikov A, Chen DY, Uzzo RG, Viterbo R, Greenberg RE, Smaldone MC. Differences in Survival Associated with Performance of Lymph Node Dissection in Patients with Invasive Penile Cancer: Results from the National Cancer Database. J Urol, 199(5):1238-44, 2018. PubMed

Goel N, Manstein SM, Ward WH, DeMora L, Smaldone MC, Farma JM, Uzzo RG, Esnaola NF. Does the Surgical Apgar Score predict serious complications after elective major cancer surgery? Journal of Surgical Research, 231:242-7, 2018. 

Smaldone, M.C., Corcoran, A.T., Hayn M.H., Konety, B.R., Hrebinko Jr., R.L., Davies, B.J. (2009). Estimation of mortality and morbidity risk in patients undergoing radical cystectomy with continent diversion using the POSSUM and Portsmouth POSSUM predictor equations. J Urol,182(6): 2619-24. PubMed

Smaldone, M.C., Cowan, J., Carroll, P.R., Davies, B.J. (2010). Comparison of eligibility for active surveillance and pathologic outcomes in men undergoing radical prostatectomy in a large community-based cohort. J Urol,183(1):138-43. PubMed

Kutikov, A., Smaldone, M.C., Egleston, B.L., Manley, B.J., Simhan, J., Boorjian, S.A., Viterbo, R., Chen, D.Y., Greenberg, R.E., Uzzo, R.G. (2011). Anatomic features of enhancing renal masses predict malignant and high-grade pathology: a preoperative nomogram using the RENAL Nephromety Score. Eur Urol, 60(2): 241-8. PubMed

Smaldone, M.C., Kutikov, A., Egleston, B., Simhan, J., Canter, D.J., Teper, E., Viterbo, R., Chen, D.Y., Greenberg, R.E., Uzzo, R.G. (2012). Assessing performance trends in laparoscopic nephrectomy and nephron sparing surgery for localized renal tumors. Urology, 80(2): 286-92. PubMed

Smaldone, M.C., Kutikov, A., Egleston, B.L., Canter, D.J., Viterbo, R., Chen, D.Y., Jewett, M.A., Greenberg, R.E., Uzzo, R.G. (2012). Small renal masses progressing to metastases under active surveillance: a systematic review and pooled analysis. Cancer, 118(4):997-1006. PubMed

Smaldone, M.C., Egleston, B.L., Uzzo, R.G., Kutikov, A. (2012). Does partial nephrectomy result in a durable overall survival benefit in the Medicare population? J Urol 188(6): 2089-94. PubMed

Kutikov, A., Egleston, B.L., Canter, D., Smaldone, M.C., Wong, Y.N., Uzzo, R.G. (2012). Competing risks of death in patients with localized renal cell carcinoma: a comorbidity based model. J Urol, 188(6): 2077-83. PubMed

Smaldone, M.C., Simhan, J., Kutikov, A., Canter, D.J., Starkey, R., Zhu, F., Nielsen, M.E., Stitzenberg, K.B., Greenberg, R.E., Uzzo, R.G. (2013) Trends in regionalization of radical cystectomy in three large northeastern states from 1996 to 2009. Urol Oncol, 31(8): 1663-9. PubMed

Tomaszewski, J.J., Uzzo, R.G., Handorf, E.A., Bekelman, J.E., Corcoran, A.T., Kutikov, A., Mehrazin, R., Smaldone, M.C. (2014) Care transitions between hospitals are associated with treatment delays for patients with muscle invasive bladder cancer. J Urol, 192(5): 1349-54. PubMed

Kim, S.P, Gross, C.P., Nguyen, P.L., Smaldone, M.C., Shah, N.D., Karnes, R.J., Thompson, R.H., Hand, L.C., Yu, J.B., Trinh, Q.D., Ziegenfuss, J.Y., Sun, M., Tilburt, J.C. (2014) Perceptions of active surveillance and treatment recommendations for low-risk prostate cancer: Results from a national survey of radiation oncologists and urologists. Med Care, 52(7):579-85. PubMed

Martin, J.M., Handorf, E.A., Kutikov, A., Uzzo, R.G., Bekelman, J.E., Horwitz, E.M., Smaldone, M.C. (2014) The rise and fall of prostate brachytherapy: Use of brachytherapy in the treatment of localized prostate cancer in the National Cancer Database. Cancer, 120(14):2114-21. PubMed

Corcoran, A.T., Handorf, E, Canter, D, Tomaszewski, J.J., Bekelman, J.E., Kim, S.P., Uzzo, R.G., Kutikov. A, Smaldone, M.C. (2015) Variation in performance of candidate surgical quality measures for muscle invasive bladder cancer by hospital type. BJU Int, 115(2):230-7. PubMed

Wang, E.H., Gross, C.P., Tilburt, J.C., Yu, J.B., Nguyen, P.L., Smaldone, M.C., Shah, N.D., Abouassally, R., Sun, M., Kim, S.P. Shared decision making and use of decision AIDS for localized prostate cancer: perceptions from radiation oncologists and urologists. (2015) JAMA Intern Med, 175(5):792-9. PubMed

Additional Publications

My NCBI

Ratings

216 PATIENT SATISFACTION REVIEWS

Our Patient Satisfaction Rating is an average of all responses to care provider related questions from our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more.

OVERALL RATING

4.9 / 5.0

RATINGS BREAKDOWN

  • 4.9
  • 4.9
  • 4.9
  • 5.0
  • 4.9

59 PATIENT COMMENTS

  • 5.0
    October 29, 2019
    Good experience. Made me confortable
  • 5.0
    October 24, 2019
    There were no gaps in the circle of events with my doctor and his staff. Gold star to everyone.
  • 5.0
    October 24, 2019
    Dr. Smaldone is the best doctor I have seen. I have the utmost confidence in him. I am glad I switched [...]. I feel great that I am getting the best care for my prostate with him and fix chase. thanks.
  • 5.0
    October 20, 2019
    Wonderful dr. - Wonderful staff.
  • 4.0
    October 17, 2019
    doc Smaldone is great
  • 5.0
    October 17, 2019
    Great care provided, thank you!
  • 5.0
    October 17, 2019
    Very professional
  • 5.0
    October 15, 2019
    Dr. Smaldone is an excellent doctor. He even gave me his cell # in case I had questions.
  • 5.0
    October 11, 2019
    good experience
  • 5.0
    October 05, 2019
    Dr.Smaldone has been excellent in handling my health care and providing me with hope for good health.
  • 5.0
    October 03, 2019
    Dr. Marc Smaldone is an excellent surgeon who truly cares about his patients. He is always available to answer questions I may have.
  • 5.0
    September 28, 2019
    Dr Smaldone is the BEST!!!
  • 5.0
    September 26, 2019
    exceptional physician nurse and reception staff
  • 5.0
    September 16, 2019
    Dr. Smaldone was easy to talk to and made me feel at ease.
  • 5.0
    September 16, 2019
    Dr. Smaldone called me on Saturday with test results. It eased my mind for the weekend.
  • 5.0
    September 03, 2019
    Dr. Smaldone is an excellent doctor!! He is the most caring, understanding, and patient doctor I have ever had. He explains things, not only listens, but hears questions, and has generally gone above and beyond in his care for me. I would recommend him to anyone who needed to see a specialist in his field. A man of integrity and genuine compassion.
  • 5.0
    August 28, 2019
    great job
  • 5.0
    August 16, 2019
    I have a good reason to be scared because of my cancer diagnosis but am optimistic and comforted by Dr Smaldone and his team.
  • 5.0
    August 12, 2019
    Overall excellent experience.
  • 5.0
    July 31, 2019
    Dr. Smaldone is a wonderful, caring clinician.
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