This Fox Chase professor participates in the Undergraduate Summer Research Fellowship.
Learn more about Research Volunteering.
Professor, Cancer Prevention and Control Program
Survivorship, QOL, Sexual Function, Breast Cancer, Interventions
Work in our lab centers on developing evidence-based interventions that aim to improve sexual health outcomes, relationships, and quality of life for those affected by cancer. We incorporate a diverse range of study designs and methods, including qualitative methodology, survey methods, communication analysis, and randomized controlled trials, which yield a deep understanding of the problems under investigation and thus help us develop feasible, acceptable, and effective interventions. Our research studies are funded by the National Cancer Institute and American Cancer Society.
Work in our lab investigates the factors contributing to cancer survivors’ psychosocial well-being and ability to cope with after-effects of cancer, with a focus on cancer-related sexual concerns. Research in our lab has demonstrated that impairments in sexual quality of life are common, distressing, and often persist if unaddressed. Findings have also illuminated the key role that cancer survivors’ intimate relationships play in survivors’ psychosocial well-being. Collectively, work in this area has contributed to the understanding of the prevalence and nature of sexual concerns for those diagnosed and treated for cancer, thus helping to pave the way feasible, acceptable, and potentially effective interventions.
In addressing the many issues that confront cancer survivors, interpersonal relationships play a critical role, and our lab has interest in developing and evaluating couple-based interventions for cancer-related health concerns, foremost of which are sexuality and intimacy. A key objective of this work is to identify how best to help couples cope. In earlier work, we elucidated a model of coping flexibly with sexual concerns in cancer that influenced subsequent intervention development. We have found promising effects of couple-based approaches for addressing sexual concerns and enhancing intimacy and related outcomes in breast and colorectal cancer, and are currently evaluating this approach in a clinical trial. We are also extending this line of research to women with metastatic breast cancer, about whom little is known with respect to their sexual and intimacy needs and who are in particular need of survivorship-related interventions. We plan to continue this work by determining optimal methods for dissemination of these approaches, once determined effective, and by assessing the utility of couple-based approaches in enhancing other outcomes in cancer populations in future studies.
An additional major area of interest in our lab is to investigate patient-provider communication about sexual health after cancer, with the ultimate aim of integrating sexual health within cancer care. Our work in this area has been instrumental in characterizing the prevalence and nature of patient-provider communication about sexual health in cancer, elucidating patient and provider barriers and facilitators of this communication, and identifying potential paths forward to improve clinical care for sexual concerns. This work is culminating in innovative provider-focused and patient-focused interventions which hold promise for integrating sexual health into cancer care and enhancing patients’ psychosocial outcomes.
Arring, N., Barton, D., Reese, J.B. (2023). Clinical Practice Strategies to Address Sexual Health in Female Cancer Survivors. Journal of Clinical Oncology, 41, 4927-4936.
Reese, J.B., Bober, S.L., Sorice, K.A., Handorf, E., Chu, C.S., Middleton, D., McIlhenny, S., & El-Jawahri, A. (2023). Starting the Conversation: Randomized Pilot Trial of an Intervention to Promote Effective Clinical Communication about Sexual Health for Gynecologic Cancer Survivors. Journal of Cancer Survivorship. ePub ahead of print, doi: 10.1007/s11764-022-01327-4.
Yankey, H.N., Lopez , M.D., Devarajan, K., Gleason, R., Pirlamarla, A.K., Dougherty, T., Dotan, E., Farma, J.M., Vijayvergia, N.E., Reese, J.B., Meyer, J.E. (2023). Prevalence and Predictors of Sexual Dysfunction (SD) after Treatment of Localized Rectal and Anal Cancer (LRAC). International Journal of Radiation, Biology & Physics, 117 (2), Suppl 1, e353.
Benedict, C., Shaffer, K.M., Wirtz, M.R., Ford, J., Reese, J.B. (2022). Current Considerations in Interventions to Address Sexual Function and Improve Care for Women with Cancer. Current Sexual Health Reports, 14, 222–230.
Arthur, E.K., Menon, U., Reese, J.B., Browning, K., Overcash, J., Rose, K., & Wills, C.E. (2022). Profiles of Women’s Adjustment after Cancer Based on Sexual and Psychosocial Wellbeing: Results of a Cluster Analysis. BMC Cancer, 22.
Gorman, J.R., Lyons, K.S., Harvey, S.M., Acquati, C., Salsman, J.M., Kashy, D.A., Drizin, J.H., Smith, E., Flexner, L.M., Hayes-Lattin, B., & Reese, J.B. (2022). Opening the Conversation: study protocol for a Phase III trial to evaluate a couple-based intervention to reduce reproductive and sexual distress among young adult breast and gynecologic cancer survivor couples. Trials, 23, 730. doi: 10.1186/s13063-022-06665-3.
Reese, J.B., El-Jawahri, A., Sorice, K., Cruz, C., Bober, S.L., Daly, M.B., Zimmaro, L.A., Beach, M.C., Wittenberg, E., Wolff, A.C., Handorf, E. & Lepore, S.J. (2022). Investigating the Impact of the COVID-19 Pandemic on Breast Cancer Clinicians’ Communication about Sexual Health. Supportive Care in Cancer, 30, 5801-5810.
Reese, J.B., Zimmaro, L.A., McIlhenny, S., Sorice, K., Porter, L.S., Zaleta, A.K., Daly, M.B., Cribb, B., & Gorman, J.R. (2022). Coping with Changes to Sex and Intimacy After a Diagnosis of Metastatic Breast Cancer: Results from a Qualitative Investigation with Patients and Partners. Frontiers in Psychology, 13, 864893. doi: 10.3389/fpsyg.2022.864893.
Shaffer, K.M., Kennedy, E., Glazer, J.V., Clayton, A.H., Cohn, W., Reese, J.B., Millard, T.A., Ritterband, L.M., & Showalter, S. (2022). Including Partners in Discussions of Sexual Side Effects from Breast Cancer: A Qualitative Study of Survivors, Partners, and Providers. Supportive Care in Cancer, 30, 4935-4944.
Zimmaro, L.A., Sorice, K., Handorf, E., Daly, M., & Reese, J.B. (2022). Understanding clinical communication about mood in breast cancer patients: A mixed methods analysis. Patient Education and Counseling, 105, 2089-2095.
Gorman, J.R., Lyons, K., Reese, J.B., Acquati, C., Smith, Drizin, J., Salsman, Hayes-Lattin, Harvey. (2022). Adapting a Theory-Informed Intervention to Help Young Adult Couples Cope with Reproductive and Sexual Concerns after Cancer. Frontiers in Psychology, 13, 813548.
Acquati, C., Hendren, S., Wittman, D., Reese, J.B., Karam, E., Duby, A., Dunn, K.B., & Kayser, K. (2022). Psychological Distress, Sexual Functioning, and Relationship Satisfaction among Rectal Cancer Patients and Their Partners During and After Treatment. Psycho-Oncology. Online ahead of print. doi: 10.1002/pon.5880
Zimmaro, L.A., Moss, A., Reibel, D.K., Handorf, E.A., Reese, J.B., & Fang, C. Y. (2021). A Telephone-Adapted Mindfulness-Based Stress Reduction Program: Preliminary Effects among Healthcare Employees. Behavioral Science, 11, 39. https://doi.org/10.3390/bs11100139
Reese, J.B., Zimmaro, L.A., Bober, S.L., Sorice, K., Handorf, E., Wittenberg, E., El-Jawahri, A., Beach, M.C., Wolff, A.C., Daly, M.B., Izquierdo, B., & Lepore, S.J. Mobile Technology-based (mLearning) Intervention to Enhance Breast Cancer Clinicians’ Communication about Sexual Health: A Pilot Trial. (2021). JNCCN, doi: 10.6004/jnccn.2021.7032
Reese, J.B., Sorice, K., Pollard, W., Handorf, E., Beach, M.C., Daly, M.B., Porter, L.S., Tulsky, J.A., & Lepore, S.J. (2021). Efficacy of a Multimedia Intervention in Enhancing Breast Cancer Patients’ Clinical Communication about Sexual Health: Results of a Randomized Controlled Trial. Psycho-Oncology, 30, 681-690.
Zimmaro, L.A., Deng, M., Handorf, E., Fang, C. Denlinger, C., & Reese, J.B. (2021). Understanding benefit finding among patients with colorectal cancer: A longitudinal study. Supportive Care in Cancer, 29, 2355-2362.
This Fox Chase professor participates in the Undergraduate Summer Research Fellowship.
Learn more about Research Volunteering.
