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Cancer Therapeutics and Discovery Targets

Technology Transfer Contacts
(technologies available for licensing)
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TECH
ID
TITLE LEAD
INVENTOR
CONTACT
96--21
MED1 (MBD4), A Novel Gene Associated with Cancer Drug Resistance 
 
 
Alfonso Bellacosa 
02--15

ATR Kinase - a Novel Target for Anti-Retroviral Drug Discovery 

Patent No. US7736848B2

Anna Marie Skalka 
03--12

Laser-Accelerated Proton Therapy

Patent No. US8269189B2; Summary

Charlie Ma Inna Khartchenko
03--13

Anti-Mullerian Inhibiting Substance Type II Receptor (MISIIR) Immuno-conjugates to Detect and Treat Cancer 

Patent No. US7781568B2

Gregory Adams Inna Khartchenko
06--16

Compositions and Methods for the Treatment of Diseases Associated with Aberrant Cilia Assembly and Regulation 

Patent No. US8685658B2

Erica Golemis Inna Khartchenko
07--05

Compositions and Methods for Altering Pancreas and Liver Functions 

Patent No. US8329467B2

Kenneth Zaret  Inna Khartchenko
07--29

Secreted/Cell Bound Poxvirus Proteins and Methods of Use Thereof as Vaccines and Antiviral Agents 

Patent No. US8557241B2 | Summary

Luis Sigal  Inna Khartchenko
07--40

EFGR/NEDD9/TGF-β Interactome and Methods for the Identification of Agents for the Treatment of Hyperproliferative Disorders

Application No. US12777112

Igor Astsaturov  Inna Khartchenko
07--44

Pregnancy Associated Genetic Signatures for Diagnosis and Treatment of Breast Cancer 

Application No. US12811303

Jose Russo and  Irma Russo  Inna Khartchenko
108-YM

Synergistic Cytotoxic Effects of 5-Fluorouracil Derivatives and 5-Hydroxymethyluracil Derivatives 

Patent No. US8617540B2

Yoshihiro Matsumoto  Inna Khartchenko
115-IR

Use of Synthetic Peptides for the Prevention and Treatment of Breast Cancer

Patent No. US8969304B2

Jose Russo and  Irma Russo  Inna Khartchenko
151-EG

Aurora  A Kinase Inhibitor and Dasatinib Combination Therapy 

Patent No. US9101631B2 | Summary

Erica Golemis Inna Khartchenko
178-AG

Gene Expression Signatures Associated with Response to Imatinib Mesylate in Gastrointestinal Stromal Tumors 

Application No. US14467984

Andrew Godwin Inna Khartchenko
196-MM

Modulators of Hsp70/ Dnak Function 

Patent No. US9296687B2

Maureen Murphy  Inna Khartchenko
222-HB

Antibodies to Tumor Endothelial Marker 7R 

Patent No. US8883978B2

Hossein Borghaei  Inna Khartchenko
243-MC

Targeting of CYP1B1 in the Treatment of Head and Neck Cancer and Lung Cancer 

Patent No. US9101603B2

Margie Clapper Inna Khartchenko
250-MA

New Drug Target Site for the Development of Inhibitors of HIV-1 Integrase for Treatment of AIDS 

Summary

Mark Andrake  Inna Khartchenko
259-RZ

Wnt5A Promotes Senescence of Epithelial Ovarian Cancer Cells by Antagonizing Canonical Wnt Signaling

Application No. US13963031

Rugang Zhang  Inna Khartchenko
264-JP

Inhibition of Activated CDC42-Associated Kinase 1

Patent No. US8658655B2

Jeffrey Peterson Inna Khartchenko
276-GA

Rationally-Designed Anti-Mullerian Inhibiting Substance Type II Receptor Antibodies

Application No. US14122286

Gregory Adams Inna Khartchenko
280-TY

Combination Inhibition of the Vitamin D Receptor and DNA Replication in the Treatment of Pancreatic and Other Cancers

Patent No. US9265787B2

Timothy Yen Inna Khartchenko
305-MC

Estrogen Metabolite Levels and CYP1B1 Polymorphisms in Lung Cancer Diagnosis, Prognosis and Risk Assessment

Application No. US14468862

Margie Clapper Inna Khartchenko
311-AB

Combination of DNA Repair Inhibition With Bendamustine or Gemcitabine in the Treatment of Cancer

Patent No. US8927516B2

Alfonso Bellacosa  Inna Khartchenko
314-VK

Methods for the Design and Development of Metallo-Enzyme Inhibitors

Patent No. US9320736B2

Vladimir Kolenko  Inna Khartchenko
326-NB

Sensitization of Cancer Cells to DNA Damage by Inhibiting Kinases Essential for DNA Damage Checkpoint Control

Patent No. US9421203B2

Timothy Yen Inna Khartchenko
332-MR

Antibodies That Specifically Bind to Serum Albumin Without Interfering With Albumin's Capability to Interact With FCRN (AntiHSA scFv)

Application No. US13826656

Matthew Robinson  Inna Khartchenko
337-ZY

Novel Treatment of Medulloblastoma with Leukotriene Inhibitors

Application No. US13833286 | Summary

Zeng-Jie Yang  Inna Khartchenko
338-HB

Method for Immune Response Detection

 

Hossein Borghaei  Inna Khartchenko
346-AB

Inhibition of Thymine DNA Glycosylase in the Treatment of Cancer

Application No. US15084680 | Summary

Alfonso Bellacosa  Inna Khartchenko
349-IA New Methods of Treatment of Pancreatic Cancer Igor Astsaturov  Inna Khartchenko
370-AT

Novel PARP 1 Inhibitors Structurally Unrelated to Nicotinamide (NAD) 

Application No. PCT/US2015/053259 | Summary

Alexei Tulin  Inna Khartchenko
372-NJ

Methods for Determining PARP Inhibitor and Platinum Resistance in Cancer Therapy

Application No. US14726682

Neil Johnson  Inna Khartchenko
381-TY

Combined Inhibition of the Vitamin D Receptor and Poly-ADP Ribose Polymerase (PARP) in the Treatment of Cancer 

Application No. US14882553 | Summary

Timothy Yen Inna Khartchenko
389-EG

Treating Polycystic Kidney Disease With HSP90 Inhibitory Compounds

 

Erica Golemis Inna Khartchenko
395-MR

Inhibition of Cancer Cell Proliferation and Selective Tumor Targeting of pHLIP-Monomethyl Auristatin conjugates 

 

Matthew Robinson  Inna Khartchenko
404-WE

Synthesis and Anti-Cancer Activity of Novel Prodigiosin Analogs 

 

Wafik El-Diery  Inna Khartchenko
407-SB

RIPK3 Activates Parallel Pathways of FADD-1 Mediated Apoptosis and MLKL2 Driven Necroptosis 

Summary

Siddharth Balachandran  Inna Khartchenko
408-VS

Anti-Cancer Drugs Curaxins Inhibit FACT Action During POL II Transcription 

 

Vasily Studitsky  Inna Khartchenko
425-MA

Small Moleclue Allosteric Inhibitors of HIV Integrase; Lead

Summary

Mark Anrake Inna Khartchenko
424-WE

MicroRNAs Targeting CDK4/6-Cell Cycle Pathway as Treatment for Cancer

Summary

Wafik El-Deiry Inna Khartchenko

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