MENU

Cancer Therapeutics and Discovery Targets

Technology Transfer Contacts
(technologies available for licensing)
Note: Links to Patents may require a browser newer than Internet Explorer 9, such as Chrome, Safari, Firefox, Edge, or Internet Explorer 11
TECH ID   TITLE  LEAD INVENTOR   CONTACT  

 02-15

ATR kinase: a novel cellular target for anti- retroviral drug discovery and therapy

Patent No. US7736848B2; Summary

  Anna Marie Skalka 

Natalia Shalginskikh

 03-12

 Laser-Accelerated Proton Therapy of Cancer

Patent No. US8269189B2

 Charlie Ma

Tatiana Venkova

 03-13

Targeted therapy for ovarian cancer: Anti-Mullerian Inhibiting Substance Type II Receptor (MISIIR) Immunoconjugates to Detect and Treat Cancer

Patent No. US7781568B2;

Patent No. US8198411B2; Summary

  Gregory Adams

Tatiana Venkova

 06-16

Treatment of diseases associated with aberrant ciliary function

Patent No. US8685658B2; Summary

 Erica Golemis

Natalia Shalginskikh

 07-05

Compositions and Methods for Altering Pancreas and Liver Functions 

Patent No. US8329467B2

 Kenneth Zaret 

Tatiana Venkova

 07-29

Secreted/cell bound poxvirus proteins and methods of use thereof as vaccines and antiviral agents

Patent No. US8557241B2; Summary

 Luis Sigal 

Natalia Shalginskikh

 07-40

EFGR/NEDD9/TGF-β Interactome and Methods for the Identification of Agents for the Treatment of Hyperproliferative Disorders

Published Application No.US20170002426A1; Summary

  Igor Astsaturov 

Natalia Shalginskikh

 96-21

MED1 (MBD4), A Novel Gene Associated with Cancer Drug Resistance

Patent No. US7208583B2

Patent No. US7491807B2

Patent No. US7829671B2

 Alfonso Bellacosa

Natalia Shalginskikh

 104-JT

Methods to Treat Hepatitis B and other Liver Disorders

Patent No. US8748373B2; Summary

 John Taylor

Natalia Shalginskikh

 108-YM

Synergistic Cytotoxic Effects of 5-Fluorouracil Derivatives and 5-Hydroxymethyluracil Derivatives

Patent No. US8617540B2

 Yoshihiro Matsumoto 

Natalia Shalginskikh

 114-EH

Method for the Treatment of Lymphangioleiomyomatosis (LAM)

Patent No. US8530457B2

 Elizabeth Henske

Natalia Shalginskikh

115-IR

Use of Synthetic Peptides for the Prevention and Treatment of Breast Cancer

Patent No. US8969304B2

 Irma Russo 

Natalia Shalginskikh

 151-EG

Combination Therapy for the Treatment of Cancer: Aurora  A Kinase Inhibitors and Dasatinib

Patent No. US9101631B2; Summary

 Erica Golemis

Natalia Shalginskikh

 196-MM

Modulators of Hsp70/ Dnak Function

Patent No. US9296687B2

 Maureen Murphy 

Natalia Shalginskikh

 222-HB

A Highly Specific Antibody Targeting Tumor Endothelial Marker 7R

Patent No. US8883978B2; Summary

Patent No. US9534050B2

 Hossein Borghaei 

Tatiana Venkova

 243-MC

Targeting of Cytochrome CYP1B1 in the Treatment of Head and Neck and Lung Cancers

Patent No. US9101603B2; Summary

 Margie Clapper

Natalia Shalginskikh

 250-MA

New Drug Target Site of HIV Integrase for AIDS Therapy

Patent No. US9533040B2; Summary

 Mark Andrake 

Natalia Shalginskikh

 259-RZ

Methods for Inducing Epithelial Cancer Cell Senescence

Published Application No.US20160354427A1

 Rugang Zhang 

Tatiana Venkova

 264-JP

Inhibition of Activated CDC42-Associated Kinase 1

Patent No. US8658655B2

 Jeffrey Peterson

Tatiana Venkova

 276-GA

Rationally-designed Anti-Mullerian Inhibiting Substance Type II Receptor Antibodies

Patent No. US9611321B2; Summary

 Gregory Adams

Inna Khartchenko

 280-TY

Combination Inhibition of the Vitamin D Receptor and DNA Replication in the Treatment of Cancer

Patent No. US9265787B2; Summary

 Timothy Yen

Tatiana Venkova

 311-AB

Combination of DNA Repair Inhibition With Bendamustine or Gemcitabine in the Treatment of Cancer

Patent No. US8927516B2

 Alfonso Bellacosa 

Natalia Shalginskikh

 314-VK

New Anticancer Zinc Chetatin Agents for Therapy of Advanced Prostate

Patent No. US9320736B2; Summary

 Vladimir Kolenko 

Natalia Shalginskikh

 326-NB

Sensitization of Cancer Cells to DNA Damage by Inhibiting Kinases Essential for DNA Damage Checkpoint Control

Patent No. US9421203B2

 Timothy Yen

Tatiana Venkova

 337-ZY

Novel Treatment of Medulloblastoma by Inhibition of Leukotriene Synthesis and Activity

Patent No. US9616056B2; Summary

 Zeng-Jie Yang 

Natalia Shalginskikh

 346-AB

Novel Methods for Inhibiting Growth and Proliferation of Melanoma Cells

Published Application No.US20160199381A1; Summary

 Alfonso Bellacosa 

Natalia Shalginskikh

 349-IA

C-MYC as a Novel Biomarker of Cancer Therapeutic Efficacy

Patent No. US9993458B2; Summary

 Igor Astsaturov 

Natalia Shalginskikh

 370-AT

Novel Class of PARP-1 Blockers for the Treatment of Prostate and Renal Cancers

Published Application No.US20170283402A1; Summary

 Alexei Tulin 

Natalia Shalginskikh

 381-TY

Combined Inhibition of the Vitamin D Receptor and Poly (ADP) Ribose Polymerase-1 (PARP-1) in Cancer Therapy

Patent No. US9889141B2; Summary

Timothy Yen

Tatiana Venkova

 389-EG

Treating Polycystic Kidney Disease With HSP90 Inhibitory Compuonds

Published Application No.WO2014063080A1

 Erica Golemis

Inna Khartchenko

 394-EG

Systems and Methods for Treating Patients Having a Genetic Predisposition to Develop Prostate Cancer

Published Application No.US20170073759A1

 Erica Golemis

Tatiana Venkova

 404-WE

Prodigiosin Analogs as Cancer Therapeutics

Published Application No.WO2017177216A1Summary

 Wafik El-Deiry 

Tatiana Venkova

 407-SB

Viral-Based Cancer Gene Therapy and Treatment of Influenza Infection Through Induction of Cell Death

Published Application No.WO2018009541A1; Summary

 Siddharth Balachandran 

Natalia Shalginskikh

 424-WE

MicroRN as Targeting CDK4/6-Cell Cycle Pathwayas Treatment for Cancer

 Patent Pending; Summary

 Wafik El-Deiry

Tatiana Venkova

 425-MA

Small Molecule Allosteric Inhibitors of HIV Integrase

 Patent Pending; Summary

 Mark Andrake

Natalia Shalginskikh

 426-SA

Methods For Diagnosis And Treatment Of Patients Having Solid Tumors

 Patent Pending

Sanjeevani Arora

Tatiana Venkova

 427-ZY

Cholesterol Synthesis Inhibitors Synergize with Smoothened Antagonist for  Treatment of Hedgehog Pathway Malignancies

 Patent Pending; Summary

 Zeng-Jie Yang 

Natalia Shalginskikh

429-RD

Chimera of Bone Morphogenic Protein 2 and the Mullerian Inhibiting Substance Type II Receptor Binding Region of Mullerian Inhibiting Substance

Patent Pending; Summary

 Roland Dunbrack

Tatiana Venkova

431-WE

High EGFR Somatic Mutation Frequency Targeting the TK Domain in Colorectal Cancer Patients with Microsatellite Instability (MSI)

Patent Pending

Wafik El-Deiry

Tatiana Venkova

432-WE

Dual Inhibition of CDK1 and HSP90 Destabilize HIF1a and Synergistically Induces Cancer Cell Death

Patent Pending

Wafik El-Deiry

Tatiana Venkova

 439-EC

Pancreatic Cancer Associated Desmoplastic Immune Checkpoint Inhibitor

Patent Pending

Edna Cukierman

Natalia Shalginskikh

 441-JR

Development of a Panel of Markers Predicting Response of Breast Cancer Prevention

Patent Pending

Jose Russo

Natalia Shalginskikh

 447-WE

TRAIL Upregulating miRNA with Apoptotic Activity

Patent Pending; Summary

Wafik El-Deiry

Tatiana Venkova

Connect with Fox Chase