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Michael J. Hall, MD, MS

Michael Hall, MD, MS
About

Associate Professor, Department of Clinical Genetics

Director, Gastrointestinal Risk Assessment 

Colorectal and SI Cancer TRDG Member

Esophagus, Pancreas, and Liver Cancer TRDG Member

NCCN, Genetic Colorectal/Colorectal Cancer Screening Panel Member

Treatment Focus

  • Gastrointestinal oncology/medical oncology
  • Cancer risk assessment for cancers of the gastrointestinal tract
  • Cancer risk assessment for endocrine cancers and genitourinary cancers

Research Program

Key Awards

America's Top Doctors®2017

Treatment Philosophy

I am a GI oncologist and a clinical cancer geneticist, and I have found over the years that my strongest skills are in helping my patients and their families to understand the complicated risks of cancer screening, surgery and treatment, to weigh the different options for treatment, and finally to develop a plan that is both in line with cutting edge research but also with their personal needs and preferences for their health and their lives. In cancer medicine, there is no longer a one size fits all approach, and in my practice I strive to build on my patients’ unique strengths and to further bring the multi-faceted expertise of my colleagues at Fox Chase and my colleagues nationally to offer each of my patients the best care I possibly can.

Education, Training & Credentials

Educational Background

  • MS, Health Studies, University of Chicago Medical Center, Chicago, IL, 2006
  • MD, Columbia College of Physicians & Surgeons, New York, NY, 1999
  • BA, French Literature, Columbia University, New York, NY, 1993

Certifications

  • Board Certified in Medical Oncology
  • Board Certified in Hematology
  • Pennsylvania Medical License

Memberships

  • American Cancer Society
  • American Society of Clinical Oncology
  • Research Review Committee, Fox Chase Cancer Center

Honors & Awards

  • Mentored Research Scholar Grant, American Cancer Society, 2007
  • Young Investigator Award, American Society of Clinical Oncology, 2006
  • Merit Award, American Society of Clinical Oncology, 2003-2005
  • Honorary Alpha Omega Alpha, University of Chicago, 2004
  • Excellence in Teaching Award, Harvard Medical School, 2001
  • Alpha Omega Alpha, Columbia College of Physicians/Surgeons, 1999
  • America's Top Doctors®, 2017
Patient Stories

Helene Mullen

Stomach Cancer

Helene Mullen

Stomach Cancer

When I started experiencing chronic and uncomfortable digestive issues over the course of two years, my primary care doctor prescribed heartburn medication, and I made changes in my diet. During that period, I often had an achy, acidy stomach, and I was taking Tums all the time. When the symptoms continued, my doctor referred me to a gastrointestinal specialist who conducted an endoscopy to examine my digestive tract in 2015.

James Gerard

Colorectal Cancer

James Gerard

Colorectal Cancer

I had already been experiencing intermittent blood in my stool for about six months when I raised my concerns with my primary care doctor. She referred me to a gastrointestinal specialist who ordered a colonoscopy at a community hospital near my home in Bucks County. That colonoscopy at age 50 likely saved my life.

Alan Stachura

Colorectal Cancer

Alan Stachura

Colorectal Cancer

Alan Stachura practically grew up at Fox Chase Cancer Center, as both his parents were treated there for cancer. Alan thought he would one day get cancer but that it wouldn't be until he was well in his 60s. However, Alan learned in 2010, at the age of 30, that he had colon cancer. Alan chose the least-invasive procedure possible, which was to remove the polyp, which turned out to be malignant. Alan also tested positive for Lynch Syndrome, and, as a result, he encouraged his siblings to be tested as well through Fox Chase's Risk Assessment Program. While Alan's brother tested negatove, his sister tested positive. Today, Alan is feeling good, but continues his regular checkups at Fox Chase to ensure the cancer does not return. "If you think there is a risk of cancer in your family, there probably is," he said. "The genetic counselors at Fox Chase's Risk Assessment Program provide valuable information and guidance. I recommend them to anyone with a strong family history of cancer."

Brooke Fuller

Colorectal Cancer

Brooke Fuller

Colorectal Cancer

Brooke Fuller enjoys working as a floral designer. She and her husband, Scott, are parents to one five-year-old son, Pierce. In January, 2014, at age 30, Brooke was diagnosed with stage 2 colorectal cancer.

Todd Jackman

Colorectal Cancer

Todd Jackman

Colorectal Cancer

Todd Jackman had no reason to suspect anything was seriously wrong with his health. At 49, the Villanova professor of biology was in the prime of his life.  His wife convinced him to see their family doctor, who suggested that Todd get a colonoscopy. It was Stage 2 colorectal cancer. Todd was urged to see an oncologist to learn what his treatment options were.

Pages

Research Profile

Research Program

Research Interests

  • Hereditary cancer risk for gastrointestinal cancers
  • Lynch syndrome, microsatellite instability, polyposis syndromes, DNA repair
  • Genetic and genomic testing in cancer patients
  • Communication of genetic risk information to patients and physicians
  • Health disparities related to genetic and genomic testing
  • Genetic basis of cancer, especially cancer in young adults

Lab Overview

The Risk Assessment Program at Fox Chase looks at your personal and possible inherited genetic factors that may put you at higher possibility for getting cancer. We comprehensively examine your profile for all cancer types, including — but not limited to — breast cancer, ovarian cancer, gastrointestinal cancers, prostate cancer, and melanoma. Knowing your risk helps you learn what you can do to lower your chances of getting cancer.

The Department of Clinical Genetics is built on the success of Fox Chase's Margaret Dyson Family Risk Assessment Program (now Risk Assessment Program), which Dr. Mary Daly began in 1991. A high-risk screening clinic was developed for individuals with a family history of breast or ovarian cancer. In addition to the clinic, genetic counseling was provided for both high risk and breast and ovarian cancer patients. As the clinic developed, it became clear that it was important to provide consultations for biopsy findings that put women at increased risk. Since then, Fox Chase has expanded risk assessment services to those at high risk for all cancers.

People

Donna Rathgeb

Administrative Coordinator

Eric Tetzlaff

PA-C –Physician Assistant

Yana Chertock, MA

Research Study Assistant

Michelle Savage, MS, LCGC

Cancer Genetic Counselor

Andrea Forman, MS, LCGC

Cancer Genetic Counselor

Kim Rainey, MS, LCGC

Cancer Genetic Counselor

Publications

Selected Publications

Arora S, Yan H, Cho I, Fan HY, Luo B, Gai X, Bodian DL, Vockley JG, Zhou Y, Handorf E, Egleston B,  Andrake M, Nicolas E, Serebriiskii IG, Yen TJ, Hall MJ, Golemis EA, Enders GH. Genetic Variants That Presdispose to DNA Double-strand Breaks in Lymphocytes from a Subset of Patients With Familial Colorectal Carcinomas. Gastroenterology. 2015 Sep 4. pii: S0016-5085(15)01259-7. doi: 10.1053/j.gastro.2015.08.052. [Epub ahead of print].

Guindalini RS, Win AK, Gulden C, Lindor NM, Newcomb PA, Haile RW, Raymond V, Stoffel E, Hall MJ, Llor X, Ukaegbu CI, Solomon I, Weitzel J, Kalady M, Blanco A, Terdiman J, Shuttlesworth GA, Lynch PM, Hampel H, Lynch HT, Jenkins MA, Olopade OI, Kupfer SS. Mutation spectrum and risk of colorectal cancer in African American families with Lynch Syndrome. Gastroenterology. 2015 Aug 3. pii: S0016-5085(15)01084-7. doi: 10.1053/j.gastro.2015.07.052. [Epub ahead of print].

Nicolas E,  Arora S, Zhou Y, Serebriiskii IG, Andrake MD, Handorf ED, Bodian DL, Vockley JG, Dunbrack RL, Ross EA, Hall MJ, Golemis EA, Giri VN, Daly MB. Systematic evaluation of underlying defects in DNA repair as an approach to case-only assessment of familial prostate cancer. (Accepted Sept 2015, Oncotarget NIHMSID # 722094).

Meyer JE, Cohen SJ, Ruth KJ, Sigurdson E, Hall MJ. Young age increases risk of lymph node positivity in  early stage rectal cancer. (Accepted Sept 2015, JNCI). 

Boland, PM, Ruth  K, Matro  JM, Rainey KL, Fang CY, Wong YN, Daly MB, Hall, MJ. Genetic counselors’ (GC) knowledge, awareness, and understanding of clinical next-generation sequencing (NGS) genomic testing. Clinical Genetics 2015. PubMed

Hall MJ, Innocent J, Rybak CM, Veloski C, Scott WJ, Wu H, Ridge JA, Hoffman JP, Borghaei H, Turaka A, Daly MB. Case Report: Bilateral granulosa cell carcinoma: A novel malignant manifestation of MEN1 syndrome associated with a rare intronic deletion. Appl Clin Gen 2014. PubMed

Hall MJ, Forman AD, Montgomery SV, Rainey KL, Daly MB. Understanding patient and provider perceptions and expectations of genomic medicine.  J Surg Oncol 2014.

Bradbury AR, Patrick-Miller L, Long J, Stopfer J, Forman A, Rybak C, Mattie K, ChungW, Churpek J, Clark-Farengo D, Daly M, Digiovanni L, Fetzer D, Ganschow P, Grana G, Gulden C, Hall MJ, Kohler L, Lorenz R, Maxwell K, Merrill S, Montgomery S, Nathanson K, Nielsen S, Olopade O, Rainey K, Seelaus C, Domchek S. Development of a tiered and binned counseling model for informed consent in the era of multiplex testing for cancer susceptibility Genet Med. 2014 Oct 9. PubMed

Hall MJ, Forman AD, Pilarski R, Wiesner G, Giri VN. Gene panel testing for inherited cancer risk. J Natl Compr Canc Netw. 2014 Sep;12(9):1339-1346. PubMed

Hall MJ. Conflicted Confidence: Academic Oncologists' Views on Multiplex Pharmacogenomic Testing. J Clin Oncol. 2014 Mar 24. PubMed

Hall MJ, Herda MM, Handorf EA, Rybak CC, Keleher CA, Siemon M, Daly MB. Direct access to universal mismatch repair (MMR) screening results for Lynch syndrome (LS) via electronic personal health record (ePHR):A feasibility study.Genet Med. 2014 May 1.

Matro JM, Ruth KJ, Wong YN, McCully KC, Rybak CM, Meropol NJ, Hall MJ. Cost-sharing and hereditary cancer risk: predictors of willingness-to-pay for genetic testing. J Genet Couns. 2014 May 6.

Hall MJ, Manne SL, Myers RE, Keenan EM, Balshem AM, Weinberg DS. Association of knowledge and race to gene environment risk assessment (GERA) testing for colorectal cancer Genome Med 2012;4(11):92 [epub ahead of print] PMID: 23194586. 

Hall MJ, Ruth K, Giri VN. Predictors of compliance with age-appropriate colorectal cancer screening in men enrolled in a prostate cancer screening program. Cancer 2012 Jan 15;118(2):478-84. 

Hall MJ, Manne SL, Winkel G, Chung DS, Weinberg DS, Meropol NJ. Effects of a decision support intervention on decisional conflict associated with microsatellite instability testing. Cancer Epidemiol Biomarkers Prev 2011;20(2):249-54. PubMed

Additional Publications

My NCBI

This Fox Chase professor participates in the Undergraduate Summer Research Fellowship
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