Elizabeth Plimack, MD, MS
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- Research Profile
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Clinical Locations
Primary Location
Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111
Chief, Division of Genitourinary Medical Oncology
Professor, Department of Hematology/Oncology
Director, Genitourinary Clinical Research
NCCN, Bladder/Penile Cancers Panel Member
NCCN, Kidney Cancer Panel Member
NCCN, Prostate Cancer Panel Member
Specialties
Research Program
Key Awards
 |
| Medical Oncology |
Treatment Philosophy
With a diagnosis of cancer comes uncertainty and fear for many patients. As a medical oncologist, my first job is to help each patient understand his or her diagnosis. With that understanding, together we can design the best plan of action. At Fox Chase, each patient has the benefit of an interdisciplinary team working together to ensure the highest quality care. This interdisciplinary approach is crucial in determining and implementing the best treatment plan.
I specialize in the treatment of kidney, bladder, prostate and testicular cancer, and my clinical practice is focused on these diseases. By concentrating exclusively on genitourinary malignancies I am able to offer expert knowledge as well as access to both standard treatments and emerging therapies in the form of clinical trials. The pace of scientific discovery has accelerated in recent decades, and fortunately we have seen these discoveries translate into meaningful improvements in cancer treatments.
As part of the genitourinary group here at Fox Chase, I am proud to be a part of a team of distinguished researchers who have pioneered many of these new treatments. My particular research efforts focus on the development of new therapies for bladder and kidney cancer.
Educational Background
- Chief Fellow, Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX
- Intern and Resident, Internal Medicine, New York University Medical Center / Bellevue Hospital, NY
- MS, Patient-Based Biologic Research, University of Texas Graduate School of Biomedical Sciences, 2008
- MD with Honors in Pathology, New York University School of Medicine, 2002
Memberships
- National Comprehensive Cancer Network (NCCN)
- Bladder/Penile Cancers Panel
- Kidney/Testicular Cancers Panel
- Prostate Cancer Panel
- American Society of Clinical Oncology (ASCO)
- 2015-2018 — ASCO Scientific Committee, Genitourinary (non-prostate)
- 2016-2017 — Track Chair, ASCO Scientific Committee, Genitourinary (non-prostate)
- 2020-2024 — Elected Member, ASCO Board of Directors
- Bladder Cancer Advocacy Network (BCAN)
- 2013-2019 — BCAN Think Tank Steering Committee
- 2016-2017 — Co-Chair, 2017 BCAN Think Tank
- 2017-2018 — Chair, 2018 BCAN Think Tank
- 2014 — Bladder Cancer Advocacy Network Young Investigator Award Study Section
- 2015-2018 — Chair, Bladder Cancer Advocacy Network Young Investigator Award Study Section
- 2018-Present — Bladder Cancer Research Network (BCRN) Management Committee
- 2020-2023 — Chair, BCAN Scientific Advisory Board
- Department of Defense (DOD) Congressionally Directed Medical Research Programs (CDMRP) Study Section
- 2015, 2016, 2017 — Reviewer, Peer Reviewed Cancer Research Program (PRCRP), Kidney Cancer
- 2020 — Chair, Peer Reviewed Cancer Research Program (PRCRP), Kidney Cancer
- 2021 — Programmatic Panel Member. Congressionally Directed Medical Research Programs: Kidney Cancer
Honors & Awards
- Philadelphia Magazine Top Doctors, 2017-20
- Best Doctors in America® , 2019-2020, Medical Oncology and Hematology
- America's Top Doctors®, 2017
- Leadership Forum Excellence Award, Fox Chase Cancer Center, 2012
- Humanitas Award, Division of Cancer Medicine Hematology/Oncology Fellowship, MD Anderson Cancer Center, 2008
- Award for Achievement in Clinical Investigation, Division of Cancer Medicine, MD Anderson Cancer Center, 2008
- Research Forum, MD Anderson Cancer Center, 2008
- Honorable Mention, First Annual Hematology/Oncology Fellowship Program, 2008
- ASCO Foundation Merit Award, ASCO Genitourinary Cancers Symposium, 2008
Donna McAllister
Donna McAllister
I was treated with compassion, given hope, and kept informed of every facet of my treatment.
Edward Robinson
Edward Robinson
I really couldn’t be happier about my experience, especially since the treatment worked!
Al De Carlo
Al De Carlo
Now that I’m 74 and retired, I spend most of my time outside or in the garage. Since my service in the Navy, where I worked as a ship fitter, taking care of the plumbing and mechanical issues, I’ve always been fascinated with machines and how they work. So for me, as crazy as it seems to my wife, working outside, tinkering with machines, and splitting wood, isn’t hard work – it’s my playtime.
Ed Horowitz
Ed Horowitz
When Ed Horowitz was diagnosed with prostate cancer in 2008, he had to make a decision whether to undergo radiation or surgery. After receiving one opinion from a surgeon at a large Philadelphia hospital, he decided to seek a second opinion from Dr. Eric Horwitz, chair of radiation oncology at Fox Chase Cancer Center. Ed liked Dr. Horowitz's warm demeanor and sense of humor and decided to be treated with IMRT (intensity modulated radiation therapy) combined with hormone injections, followed by radiation and hormone therapy. The treatment was successful. A few years later, his cancer returned, isolated to his shoulder this time. Ed started another course of chemotherapy in March 2016. "My cancer has not grown and has not spread since I completed chemotherapy," he said. "I always recommend Fox Chase to anyone considering treatment for prostate cancer. I consider myself fortunate to have gone there for treatment."
Pages
Research Program
Research Interests
- Biomarkers predictive of response to neoadjuvant cisplatin based chemotherapy in bladder cancer
- Refining neoadjuvant chemotherapy regimens for bladder cancer
- Developmental Therapeutics – early stage clinical trials of novel agents
- Immunotherapy in GU Malignancies
Selected Publications
Bamias A, Tzannis K, Bamia C, Harshman LC, Crabb S, Plimack ER, Pal S, De Giorgi U, Ladoire S, Theodore C, Agarwal N, Yu EY, Niegisch G, Sternberg CN, Srinivas S, Vaishampayan U, Necchi A, Liontos M, Rosenberg JE, Powles T, Bellmunt J, Galsky MD. The Impact of Cisplatin- or Non-Cisplatin-Containing Chemotherapy on Long-Term and Conditional Survival of Patients with Advanced Urinary Tract Cancer. The oncologist, 2019.
Changa NM, Xie WL, Bilen MA, Dzimitrowicz H, Burkart J, Geynisman DM, Balakrishnan A, Bowman IA, Jain R, Stadler W, Zakharia Y, Narayan V, Beuselinck B, McKay RR, Tripathi A, Pachynski R, Hahn AW, Hsu J, Shah SA, Lam ET, Rose TL, Mega AE, Vogelzang N, Harrison MR, Mortazavi A, Plimack ER, Vaishampayan U, Hammers H, George S, Haas N, Agarwal N, Pal SK, Srinivas S, Carneiro BA, Heng DYC, Bosse D, Choueiri TK, Harshman LC. Cabozantinib in advanced non-clear-cell renal cell carcinoma: a multicentre, retrospective, cohort study. Lancet Oncology, 20(4):581-90, 2019.
Rouvinov K, Plimack ER, Zibelman M, Ghatalia P, Geynisman DM. Update on perioperative systemic therapy for urothelial carcinoma. Clinical advances in hematology & oncology : H&O, 17(3):176-83, 2019.
Voss MH, Bhatt RS, Vogelzang NJ, Fishman M, Alter RS, Rini BI, Beck JT, Joshi M, Hauke R, Atkins MB, Burgess E, Logan TF, Shaffer D, Parikh R, Moazzam N, Zhang X, Glasser C, Sherman ML, Plimack ER. A phase 2, randomized trial evaluating the combination of dalantercept plus axitinib in patients with advanced clear cell renal cell carcinoma. Cancer, 2019.
Amin A, Plimack ER, Ernstoff MS, Lewis LD, Bauer TM, McDermott DF, Carducci M, Kollmannsberger C, Rini BI, Heng DYC, Knox J, Voss MH, Spratlin J, Berghorn E, Yang L, Hammers HJ. Correction to: Safety and efficacy of nivolumab in combination with sunitinib or pazopanib in advanced or metastatic renal cell carcinoma: the CheckMate 016 study. Journal for immunotherapy of cancer, 7(1):73, 2019. PMC6416882
He AR, Cohen RB, Denlinger CS, Sama A, Birnbaum A, Hwang J, Sato T, Lewis N, Mynderse M, Niland M, Giles J, Wallin J, Moser B, Zhang W, Walgren R, Plimack ER. First-in-Human Phase I Study of Merestinib, an Oral Multikinase Inhibitor, in Patients with Advanced Cancer. The oncologist, 2019.
Martinez Chanza N, Xie W, Asim Bilen M, Dzimitrowicz H, Burkart J, Geynisman DM, Balakrishnan A, Bowman IA, Jain R, Stadler W, Zakharia Y, Narayan V, Beuselinck B, McKay RR, Tripathi A, Pachynski R, Hahn AW, Hsu J, Shah SA, Lam ET, Rose TL, Mega AE, Vogelzang N, Harrison MR, Mortazavi A, Plimack ER, Vaishampayan U, Hammers H, George S, Haas N, Agarwal N, Pal SK, Srinivas S, Carneiro BA, Heng DYC, Bosse D, Choueiri TK, Harshman LC. Cabozantinib in advanced non-clear-cell renal cell carcinoma: a multicentre, retrospective, cohort study. The Lancet Oncology, 2019.
Godwin JL, Hoffman-Censits J, Plimack E. Recent developments in the treatment of advanced bladder cancer. Urologic oncology, 36(3):109-14, 2018. PubMed
Geynisman DM, Abbosh PH, Plimack ER, Zibelman M. Chemoimmunotherapy in Metastatic Urothelial Carcinoma. Eur Urol, 2018.
Additional Publications
Clinical Locations
Primary Location
Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111
Chief, Division of Genitourinary Medical Oncology
Professor, Department of Hematology/Oncology
Director, Genitourinary Clinical Research
NCCN, Bladder/Penile Cancers Panel Member
NCCN, Kidney Cancer Panel Member
NCCN, Prostate Cancer Panel Member
Research Program
Key Awards
|
| Medical Oncology |
Treatment Philosophy
With a diagnosis of cancer comes uncertainty and fear for many patients. As a medical oncologist, my first job is to help each patient understand his or her diagnosis. With that understanding, together we can design the best plan of action. At Fox Chase, each patient has the benefit of an interdisciplinary team working together to ensure the highest quality care. This interdisciplinary approach is crucial in determining and implementing the best treatment plan.
I specialize in the treatment of kidney, bladder, prostate and testicular cancer, and my clinical practice is focused on these diseases. By concentrating exclusively on genitourinary malignancies I am able to offer expert knowledge as well as access to both standard treatments and emerging therapies in the form of clinical trials. The pace of scientific discovery has accelerated in recent decades, and fortunately we have seen these discoveries translate into meaningful improvements in cancer treatments.
As part of the genitourinary group here at Fox Chase, I am proud to be a part of a team of distinguished researchers who have pioneered many of these new treatments. My particular research efforts focus on the development of new therapies for bladder and kidney cancer.
Education
Educational Background
- Chief Fellow, Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX
- Intern and Resident, Internal Medicine, New York University Medical Center / Bellevue Hospital, NY
- MS, Patient-Based Biologic Research, University of Texas Graduate School of Biomedical Sciences, 2008
- MD with Honors in Pathology, New York University School of Medicine, 2002
Memberships
- National Comprehensive Cancer Network (NCCN)
- Bladder/Penile Cancers Panel
- Kidney/Testicular Cancers Panel
- Prostate Cancer Panel
- American Society of Clinical Oncology (ASCO)
- 2015-2018 — ASCO Scientific Committee, Genitourinary (non-prostate)
- 2016-2017 — Track Chair, ASCO Scientific Committee, Genitourinary (non-prostate)
- 2020-2024 — Elected Member, ASCO Board of Directors
- Bladder Cancer Advocacy Network (BCAN)
- 2013-2019 — BCAN Think Tank Steering Committee
- 2016-2017 — Co-Chair, 2017 BCAN Think Tank
- 2017-2018 — Chair, 2018 BCAN Think Tank
- 2014 — Bladder Cancer Advocacy Network Young Investigator Award Study Section
- 2015-2018 — Chair, Bladder Cancer Advocacy Network Young Investigator Award Study Section
- 2018-Present — Bladder Cancer Research Network (BCRN) Management Committee
- 2020-2023 — Chair, BCAN Scientific Advisory Board
- Department of Defense (DOD) Congressionally Directed Medical Research Programs (CDMRP) Study Section
- 2015, 2016, 2017 — Reviewer, Peer Reviewed Cancer Research Program (PRCRP), Kidney Cancer
- 2020 — Chair, Peer Reviewed Cancer Research Program (PRCRP), Kidney Cancer
- 2021 — Programmatic Panel Member. Congressionally Directed Medical Research Programs: Kidney Cancer
Honors & Awards
- Philadelphia Magazine Top Doctors, 2017-20
- Best Doctors in America® , 2019-2020, Medical Oncology and Hematology
- America's Top Doctors®, 2017
- Leadership Forum Excellence Award, Fox Chase Cancer Center, 2012
- Humanitas Award, Division of Cancer Medicine Hematology/Oncology Fellowship, MD Anderson Cancer Center, 2008
- Award for Achievement in Clinical Investigation, Division of Cancer Medicine, MD Anderson Cancer Center, 2008
- Research Forum, MD Anderson Cancer Center, 2008
- Honorable Mention, First Annual Hematology/Oncology Fellowship Program, 2008
- ASCO Foundation Merit Award, ASCO Genitourinary Cancers Symposium, 2008
Research Profile
Research Interests
- Biomarkers predictive of response to neoadjuvant cisplatin based chemotherapy in bladder cancer
- Refining neoadjuvant chemotherapy regimens for bladder cancer
- Developmental Therapeutics – early stage clinical trials of novel agents
- Immunotherapy in GU Malignancies
Publications
Selected Publications
Bamias A, Tzannis K, Bamia C, Harshman LC, Crabb S, Plimack ER, Pal S, De Giorgi U, Ladoire S, Theodore C, Agarwal N, Yu EY, Niegisch G, Sternberg CN, Srinivas S, Vaishampayan U, Necchi A, Liontos M, Rosenberg JE, Powles T, Bellmunt J, Galsky MD. The Impact of Cisplatin- or Non-Cisplatin-Containing Chemotherapy on Long-Term and Conditional Survival of Patients with Advanced Urinary Tract Cancer. The oncologist, 2019.
Changa NM, Xie WL, Bilen MA, Dzimitrowicz H, Burkart J, Geynisman DM, Balakrishnan A, Bowman IA, Jain R, Stadler W, Zakharia Y, Narayan V, Beuselinck B, McKay RR, Tripathi A, Pachynski R, Hahn AW, Hsu J, Shah SA, Lam ET, Rose TL, Mega AE, Vogelzang N, Harrison MR, Mortazavi A, Plimack ER, Vaishampayan U, Hammers H, George S, Haas N, Agarwal N, Pal SK, Srinivas S, Carneiro BA, Heng DYC, Bosse D, Choueiri TK, Harshman LC. Cabozantinib in advanced non-clear-cell renal cell carcinoma: a multicentre, retrospective, cohort study. Lancet Oncology, 20(4):581-90, 2019.
Rouvinov K, Plimack ER, Zibelman M, Ghatalia P, Geynisman DM. Update on perioperative systemic therapy for urothelial carcinoma. Clinical advances in hematology & oncology : H&O, 17(3):176-83, 2019.
Voss MH, Bhatt RS, Vogelzang NJ, Fishman M, Alter RS, Rini BI, Beck JT, Joshi M, Hauke R, Atkins MB, Burgess E, Logan TF, Shaffer D, Parikh R, Moazzam N, Zhang X, Glasser C, Sherman ML, Plimack ER. A phase 2, randomized trial evaluating the combination of dalantercept plus axitinib in patients with advanced clear cell renal cell carcinoma. Cancer, 2019.
Amin A, Plimack ER, Ernstoff MS, Lewis LD, Bauer TM, McDermott DF, Carducci M, Kollmannsberger C, Rini BI, Heng DYC, Knox J, Voss MH, Spratlin J, Berghorn E, Yang L, Hammers HJ. Correction to: Safety and efficacy of nivolumab in combination with sunitinib or pazopanib in advanced or metastatic renal cell carcinoma: the CheckMate 016 study. Journal for immunotherapy of cancer, 7(1):73, 2019. PMC6416882
He AR, Cohen RB, Denlinger CS, Sama A, Birnbaum A, Hwang J, Sato T, Lewis N, Mynderse M, Niland M, Giles J, Wallin J, Moser B, Zhang W, Walgren R, Plimack ER. First-in-Human Phase I Study of Merestinib, an Oral Multikinase Inhibitor, in Patients with Advanced Cancer. The oncologist, 2019.
Martinez Chanza N, Xie W, Asim Bilen M, Dzimitrowicz H, Burkart J, Geynisman DM, Balakrishnan A, Bowman IA, Jain R, Stadler W, Zakharia Y, Narayan V, Beuselinck B, McKay RR, Tripathi A, Pachynski R, Hahn AW, Hsu J, Shah SA, Lam ET, Rose TL, Mega AE, Vogelzang N, Harrison MR, Mortazavi A, Plimack ER, Vaishampayan U, Hammers H, George S, Haas N, Agarwal N, Pal SK, Srinivas S, Carneiro BA, Heng DYC, Bosse D, Choueiri TK, Harshman LC. Cabozantinib in advanced non-clear-cell renal cell carcinoma: a multicentre, retrospective, cohort study. The Lancet Oncology, 2019.
Godwin JL, Hoffman-Censits J, Plimack E. Recent developments in the treatment of advanced bladder cancer. Urologic oncology, 36(3):109-14, 2018. PubMed
Geynisman DM, Abbosh PH, Plimack ER, Zibelman M. Chemoimmunotherapy in Metastatic Urothelial Carcinoma. Eur Urol, 2018.
Additional Publications
Related Articles
15 PATIENT COMMENTS
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5.0
March 22, 2021
always good experience
-
5.0
March 01, 2021
All good.
-
5.0
January 29, 2021
Professional, consistently
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5.0
January 21, 2021
Dr. Elizabeth Plimack, MD is very acknowledgement doctor. My fiance made me have a 2nd opinion and they agree with her decisions for my treatment.
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5.0
December 28, 2020
[...] & Dr. Plimack worked together beautifully in the care relationship!
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5.0
November 25, 2020
Excellent care & courtesy & hopefully excellent results.
-
5.0
September 04, 2020
It was a routine follow up appointment but, Dr. Plimack was thorough as usual.
-
5.0
July 17, 2020
good
-
5.0
June 17, 2020
All visits with Dr. Plimack or one of her staff have been very good. Video visit.
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5.0
May 25, 2020
Very good.
-
5.0
May 20, 2020
My provider and staff have always been the best!!!!!!
-
5.0
April 23, 2020
Dr Plimack is an outstanding physician. she is a great listener and always answers any questions I may ask. I have a tremendous amount of confidence in Dr Plimack and her treatment of my condition.
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5.0
April 10, 2020
Very good experience All test went very will
-
5.0
March 23, 2020
Excellent experience.
-
5.0
March 19, 2020
[...] exceptional!
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