Christopher J. Manley, MD

Christopher Manley, MD
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Clinical Locations

Director, Interventional Pulmonology

Associate Professor, Department of Medicine

Treatment Focus

Interventional Pulmonology and Critical Care

  • Interventional Pulmonology: Minimally invasive procedures to diagnose and treat lung cancer, benign and malignant causes of airway obstruction, and pleural disease.
  • Critical Care: Taking care of patients who require the intensive care unit (ICU)

Key Awards

2023 top doctors
Pulmonary Disease

Treatment Philosophy

As an interventional pulmonologist I work as part of a large multi-disciplinary team to diagnose and treat cancers involving the lung.  Both primary lung cancers and other cancers that involve the lung can make people feel short of breath and limit activity which leads to a worse quality of life.  However, while patients are undergoing treatment of lung cancers, we can employ many minimally invasive techniques to treat shortness of breath and improve lung function.  This helps people keep feeling well and stay active. 

Educational Background

  • Fellow, Interventional Pulmonology, Harvard Combined, Beth Israel Deaconess Hospital and Massachusetts General Hospital, Boston, MA, 2015-2016
  • Fellow, Pulmonary and Critical Care Medicine, Tufts Medical Center, Boston, MA, 2012-2015
  • Resident, Internal Medicine, Loyola University, Chicago, IL, 2009-2012
  • MD, Honors in Research and Bioethics, Chicago Stritch School of Medicine, Loyola University, Chicago, IL, 2009
  • BA, History and Pre-Medicine, College of the Holy Cross, Worchester, MA, 2004


  • Board Certification in Interventional Pulmonology
  • Board Certification in Pulmonary Medicine
  • Board Certification in Critical Care  
  • Board Certification in Internal Medicine


  • American Association of Bronchology and Interventional Pulmonology
  • ​American College of Chest Physicians
  • American Thoracic Society

Honors & Awards

  • Philadelphia Magazine Top Doctors, 2020

Tiffany Fagnani

  • Lung Cancer

I am 40 years old and currently live in Mechanicsburg, Pennsylvania. Although I work as a case manager for an insurance company now, I was previously employed as a full-time nurse. I have always been a busy person with plenty on my plate, so when I started feeling tired and losing weight, I thought it was caused by the stress of my daily routine.

It wasn’t until July 2017 that I couldn’t ignore my symptoms any longer. When I developed a migraine and felt a tremor in my arm and eye, I knew I was about to lose consciousness. I immediately called 911.


Joyce Vrbicek

  • Lung Cancer

Before cancer, I was a retired Philadelphia police officer who enjoyed many wonderful adventures with my husband, Braco. We enjoyed running businesses together, traveling together, and raising our daughters together. But, when Braco was diagnosed with lung cancer in 2016 at the age of 57, everything changed. And, a few years later in 2019, I was faced with my own lung cancer diagnosis.


Research Interests

  • Central airway tumors
  • Treatment of pleural effusions

Selected Publications

Ismail K, Roberts K, Manning P, Manley C, Hill N. Obstructive Sleep Apnea and Pulmonary Hypertension: Time for a Re-examination? Chest. Mar 1;147(3):847-61, 2015.

Manley C, Garpestad E, Hill N. A New Purpose For Proportional Assist Ventilation? Critical Care Medicine. Sep;41(9): 2230-1, 2013.

Goyal A,Yazicioglu-Mocin O, Manley C, Schnell T, Collins E, Jubran A, Tobin M, Laghi F. Does Contractile Fatigue Modulate Quadriceps Endurance In Patients With COPD. Am. J. Respir. Crit. Care Med.;183: A2531, 2011.

Mampilly J, Yazicioglu-Mocin O, Manley C, Collins E, Laghi F, Tobin M, Jubran A. Assessment Of Muscle Wasting In ICU Patients Using Ultrasonography Of The Rectus Femoris. Am. J. Respir. Crit. Care Med; 183: A4248, 2011.

Brewster LP, Palmatier J, Manley C,  Hall D, Brems J. Limitations on Surrogate Decision-Making for Emergent Liver Transplantation. Journal of Surgical Research, May 18 2011.

Snopko  R, Ramos-Franco J, Di Maio A, Karko K, Manley C, Piedras-Renteria E, Mejia-Alvarez R. Ca2+ Sparks and Cellular Distribution of Ryanodine Receptors in Developing Cardio-Myocytes from Rat. Journal of Molecular and Cellular Cardiology. 44, 6, Pgs 1032-1044 June 2008.

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