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Fox Chase Cancer Center News

May 16, 2011

New Findings Show that the Protein Abcc10 May be Effective in Counteracting Resistance and Extending the Effectiveness of Some Anticancer Drugs

PHILADELPHIA, PA (May 16, 2011) — Today’s anticancer drugs often work wonders against malignancies, but sometimes tumors become resistant to the effects of such drugs, and treatment fails. Medical researchers would like to find ways of counteracting such resistance, but first they must understand why and how it happens.

May 1, 2011

Fox Chase Researchers Find that Aspirin Reduces the Risk of Cancer Recurrence in Some Prostate Cancer Patients

PALM BEACH, FL (May 1, 2011) – Some studies have shown that blood-thinning medications, such as aspirin, can reduce biochemical failure––cancer recurrence that is detected by a rising prostate-specific antigen (PSA) level––the risk of metastasis and even death in localized prostate cancer. These studies, although very telling, have all emphasized the need for more data. Now, with researchers at Fox Chase Cancer Center having concluded the largest study on this topic, and there is substantial data suggesting that aspirin improves outcomes in prostate cancer patients who have received radioth

April 28, 2011

Perceived Stress and Depressive Symptoms Are Associated with Biomarkers Indicative of Shorter Disease-Free Survival in Head and Neck Cancer Patients

Washington, DC (April 28, 2011) – Studies have shown that stress can affect the immune system and weaken the body’s defense against infection and disease.  In cancer patients this stress can also affect a tumor’s ability to grow and spread. However, the biological mechanisms that underlie such associations are not well understood.

Baruch S. Blumberg, MD, PhD
April 7, 2011

Nobelist Baruch S. Blumberg, MD, PhD, Dies at 85

PHILADELPHIA, PA (April 7, 2011) – Baruch S. Blumberg, MD, PhD, winner of the 1976 Nobel Prize in Medicine and longtime Fox Chase faculty member, died of an apparent heart attack Tuesday, April 5, 2011, shortly after delivering a keynote address at a NASA conference in California.

Jose Russo, MD
April 6, 2011

Fox Chase Researchers Find that Fish Oil Boosts Responses to Breast Cancer Drug Tamoxifen

ORLANDO, FL (April 6, 2011) – Breast cancer is the second most common cancer among women, with more than 200,000 women diagnosed each year. Being exposed to estrogen over a long period of time is one factor that can increase a woman's risk of developing the disease.  One way a woman can combat this risk factor is by taking the breast cancer drug tamoxifen, which interferes with the activity of estrogen.  Now, researchers at Fox Chase Cancer Center have found that omega-3 fatty acids—abundant in fish—could be a safe and beneficial booster for tamoxifen therapy.

April 6, 2011

Fox Chase Researchers Report that Naproxen Reduces Tumors in a Mouse Model of Colon Cancer

ORLANDO, FL (April 6, 2011) – Numerous studies show that non-steroidal anti-inflammatory drugs (NSAIDs) reduce the risk of colon cancer. However, animal studies testing the NSAID naproxen or its derivative, NO-naproxen, have focused primarily on chemically-induced tumor formation. Now, researchers at Fox Chase Cancer Center find that naproxen and NO-naproxen reduce tumor formation in a strain of mutant mice that spontaneously develop colon tumors. The data also suggest that naproxen blocks a gatekeeper step that initiates tumor formation.

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