Anthony J. Olszanski, MD, RPh

Anthony Olszanski, MD

Clinical Locations

Primary Location

Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111


Vice Chair, Department of Hematology/Oncology

Chief, Section of Solid Tumor Oncology

Co-Director, Melanoma and Skin Cancer Program

Director, Early Clinical Drug Development Phase 1 Program ​

TRDG Member, Colorectal and SI CancerLung Cancer and MesotheliomaMelanoma and Skin Cancer

NCCN, Melanoma Panel Member

Treatment Focus

Early Clinical Drug Development/Phase 1 Trials; Melanoma and skin cancer; Lung cancers; Gastrointestinal cancers

Research Program

Treatment Philosophy

I believe that the path towards treating any disease is best navigated by thoroughly understanding not only the disease, but also the patient. Good communication between a physician and a patient is especially critical in the treatment of cancer. Each patient has a right to be both respected and heard. In addition, relying on a team of experts to help manage the complexities of treating cancer is essential for success. As a physician, I strive to provide personalized and scientifically sound care to each of my patients.

My medical career started out as a pharmacist, specializing in oncology, where I prepared chemotherapy regimens and studied the effects the body has on drugs (pharmacokinetics).  When I went to medical school, it was for the sole purpose of eventually becoming an oncologist. During my hematology/oncology and clinical pharmacology fellowships, I spent a great deal of time in early clinical development, with a goal of finding new effective therapies for patients with cancer.  I honed my knowledge of drug discovery by spending five years in the pharmaceutical industry where I led multiple programs aimed at treating patients with cancers that didn’t respond to traditional chemotherapy. Today, my interests focus on early drug development for all types of cancers, and understanding how each medication may best be used. In addition I specifically focus on the treatment of lung cancer, skin cancers including melanoma, and gastrointestinal malignancies.

In many situations, the best medical care a patient with cancer can get is on a clinical trial. These clinical trials offer patients potentially promising new therapies and very close follow up supplied by a team of experts. Fox Chase Cancer Center, with its leading-edge technology and dedicated medical professionals, offers numerous clinical trials and is helping to advance the care of all patients with cancer.

The staff at Fox Chase Cancer Center continually impress me with their unified commitment towards reducing the burden of cancer. When you step through the doors at Fox Chase Cancer Center, it is obvious that focusing on the patient is the top priority. I am proud to be a member of the caring community at FCCC, where oncology research and science is tailored and personalized for each patient.

Education and Training

Educational Background

  • Fellow, Clinical Pharmacology/Toxicology, Oncology Phase I Program, Department of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH 2002-2004
  • Fellow, Hematology/Oncology, Department of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH, 1999-2002
  • Resident, Internal Medicine, Department of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH, 1996-1999
  • Resident, Biostatistics, Center for Evaluative Clinical Sciences, Dartmouth Medical School, Hanover, NH, 2003
  • MD, University of Medicine and Dentistry of New Jersey, Newark, NJ, 1996
  • BS, Pharmacy, University of Montana, Missoula, MT, 1990


  • Board Certified in Medical Oncology
  • Board Certified in Clinical Pharmacology


  • National Comprehensive Cancer Network (NCCN)
    • International Program Steering Committee
    • Melanoma Panel
    • NCCN ORP Investigator Steering Committee
  • American Board of Clinical Pharmacology
  • American Society of Clinical Oncology

Honors & Awards

  • Robert L. Krigel Memorial Award: Excellence in Teaching and Clinical Oncology, 2014
Patient Stories

Mary Carr

Colorectal Cancer

Mary Carr

Colorectal Cancer

I started feeling ill in January 2011. My stomach was constantly upset and I couldn’t hold down food. My local doctor said I had the flu, but my weight continued to decrease over the next several months. That doctor sent me to an internist, who also could not find the cause of my illness. In May, the internist ordered a colonoscopy.

Donna Piunt

Melanoma;  Skin Cancer

Donna Piunt

Melanoma;  Skin Cancer

In November 2011, Donna Piunt was driving along to work like any other 51-year-old, jamming to music in her car. She and her husband, Stefan, were happily married and they had two beautiful daughters in their twenties. Donna arrived to work with a smile on her face as she greeted the little boy she cared for a nanny. In her spare time, she was pursuing her Associate’s Degree in medical billing and coding, which she could work on while the little boy napped.


Selected Publications

Phase I study of the mTOR inhibitor ridaforolimus and the HDAC inhibitor vorinostat in advanced renal cell carcinoma and other solid tumors. Zibelman M, Wong YN, Devarajan K, Malizzia L, Corrigan A, et al. Investigational new drugs. 2015; 33(5):1040-7. PubMed

Phase I dose-escalation study of cabazitaxel administered in combination with gemcitabine in patients with metastatic or unresectable advanced solid malignancies. Rixe O, Puzanov I, LoRusso PM, Cohen RB, Morris JC, et al. Anti-cancer drugs. 2015; 26(7):785-92. PubMed

Principles of immunotherapy. Olszanski AJ. Journal of the National Comprehensive Cancer Network : JNCCN. 2015; 13(5 Suppl):670-2. PubMed

Additional Publications




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