Stephen C. Rubin, MD
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Clinical Locations
Primary Location
Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111
Chief, Division of Gynecologic Oncology
Professor, Department of Surgical Oncology
Specialties
Treatment Focus
Surgery and chemotherapy for all gynecologic cancers; minimally invasive surgery for gynecologic cancers, precancerous conditions and benign gynecologic conditions
Key Awards
 |
| Gynecologic Oncology |
Treatment Philosophy
I joined Fox Chase Cancer Center in 2014 as chief of the Division of Gynecologic Oncology. I spent the early part of my medical career at Memorial Sloan-Kettering Cancer Center in New York and the Hospital of the University of Pennsylvania, where I was chief of gynecologic oncology. As a gynecologic oncologist, I have extensive training and experience in surgery (including minimally invasive) for gynecologic cancers and for complex benign gynecologic conditions. I also provide the full range of chemotherapy options for gynecologic cancers, giving my patients the continuity of care that comes with multimodal cancer care.
I am delighted to be practicing at Fox Chase, where I offer patients state-of-the-art care, including innovative clinical trials, in a caring, compassionate environment, with all the support services that come from an NCI-designated Comprehensive Cancer Center.
Educational Background
- Fellow, Gynecologic Oncology, Hospital of the University of Pennsylvania, Philadelphia, PA, 1982
- Resident, Obstetrics & Gynecology, Hospital of the University of Pennsylvania, Philadelphia, PA, 1980
- MD, University of Pennsylvania School of Medicine, Philadelphia, PA, 1976
Certifications
- American Board of Obstetrics and Gynecology
- American Board of Obstetrics and Gynecology, Division of Gynecologic Oncology
Memberships
- American Association of Gynecologic Laparoscopists
- American College of Obstetricians and Gynecologists
- American College of Surgeons
- American Federation for Clinical Research
- American Gynecological and Obstetrical Society
- American Radium Society
- American Society of Clinical Oncology
- American Society for Colposcopy and Cervical Cytology
- Association of Professors of Gynecology and Obstetrics
- Society of Gynecologic Oncologists
- Society for Gynecologic Investigation
- Society of Pelvic Surgeons
- Society of Surgical Oncology
- International Gynecologic Cancer Society
- European Society of Gynecological Oncology
- Felix Rutledge Society
- New York Academy of Sciences
- New York Obstetrical Society
- New York Gynecological Society
- Obstetrical Society of Philadelphia
- Philadelphia Colposcopy Society
- Philadelphia College of Physicians
- Mid-Atlantic Gynecologic Oncology Society
Honors & Awards
- Philadelphia Magazine Top Doctors, 1993-20
- Best Doctors in America® , 2014, 2019-2020
- America’s Top Doctors®, 2015-17
- MA honoris causa, University of Pennsylvania, 1994
- Presidential Award, Society of Gynecologic Oncologists, 1993
- Boyer Award for Clinical Investigation, Memorial Sloan-Kettering Cancer Center, 1990
- Clinical Oncology Career Development Award, American Cancer Society, 1987-90
- Chief Resident's Teaching Award, Medical College of Pennsylvania, 1983
- Clinical Fellow, American Cancer Society, 1980-82
Mary Schwarzenberger
Mary Schwarzenberger
“My doctor told me Dr. Rubin ‘wrote the book’ on gynecologic surgery and was at the top of his class. This was someone he would send his loved ones to, if needed. That was all the endorsement I needed to hear.”
Joan Foley
Joan Foley
When Joan Foley learned she had ovarian cancer, she did her research and read great things about Dr. Stephen Rubin at Fox Chase Cancer Center. At Fox Chase, Joan underwent surgery less than a week after her initial consultation with Dr. Rubin. Following surgery, she also underwent chemotherapy for 18 weeks. Today, Joan is feeling goos and is back to working as a researcher at a university in Philadelphia. "I recommend that anyone diagnosed with cancer should do their homework and research well-regarded oncologists who have expertise in a specific diagnostic area of cancer," she said. "My family now contributes to a research fellowship program led by Dr. Rubin to train research fellows in the field of gynecologic cancers...Because Fox Chase is a research institution, it offers patients a treatment edge, and research at Fox Chase can inform existing treatment protocols to yield better outcomes now and in the future."
Mary Haspel
Mary Haspel
Mary Haspel received several false diagnoses for what was first diagnosed as a urinary tract infection. Eventually, after a number of tests, she was diagnosed with ovarian cancer. Mary's doctor referred her to Fox Chase Cancer Center, where she underwent a hysterectomy. The next stage of treatment was an 18-week course of chemotherapy, followed by 12 monthly treatments. The treatment was successful, and Mary returned to her normal life, but decided to retire so she could pursue other interests, such as teaching yoga. In March 2017, she was diagnosed with a small recurrence of cancer, but is responding well to the chemotherapy and feels positive about the outcome.
Lizbeth Brunswick
Lizbeth Brunswick
Lizbeth Brunswick was 60 years old and had never been in the hospital when she was diagnosed with ovarian cancer in 2014. Her gynecologist recommended she seek treatment with Dr. Stephen Rubin at Fox Chase Cancer Center, where she underwent surgery and an 18-week course of chemotherapy, all while continuing her work life in New York City. In October 2016, she spoke at the Fox Chase Cancer Center Laurel Society event at The Kimmel Center for Performing Arts, where she described not only her experience with cancer treatment at Fox Chase but also her belief in the importance of philanthropy to support cancer research. "I know I would not be where I am today if it weren’t for everyone at Fox Chase," Lizbeth said. "I believe that by giving back, we give others the chance to beat this disease. Without research there is no cure."
Debbie Richards
Debbie Richards
Debbie did her research and asked a highly regarded gynecologist, “Who would you go to if someone in your family had ovarian cancer?” The answer was Dr. Stephen Rubin.
Research Interests
- Clinical trials and innovative therapies for gynecologic cancers
Selected Publications
Resilience, Positive Coping, and Quality of Life Among Women Newly Diagnosed With Gynecological Cancers. Manne SL, Myers-Virtue S, Kashy D, Ozga M, Kissane D, Heckman C, Rubin SC, Rosenblum N. Cancer Nurs. 2015 Sep-Oct;38(5):375-82. doi: 10.1097/NCC.0000000000000215.
Correlation of pelvic magnetic resonance imaging diagnosis with pathology for indeterminate adnexal masses. Haggerty AF, Hagemann AR, Chu C, Siegelman ES, Rubin SC. Int J Gynecol Cancer. 2014 Sep;24(7):1215-21. doi: 10.1097/IGC.0000000000000203. PMID: 25153677
Risk factors for GI adverse events in a phase III randomized trial of bevacizumab in first-line therapy of advanced ovarian cancer: A Gynecologic Oncology Group Study. Burger RA, Brady MF, Bookman MA, Monk BJ, Walker JL, Homesley HD, Fowler J, Greer BE, Boente M, Fleming GF, Lim PC, Rubin SC, Katsumata N, Liang SX. J Clin Oncol. 2014 Apr 20;32(12):1210-7. doi: 10.1200/JCO.2013.53.6524. Epub 2014 Mar 17. PMID: 24637999
Paget Cells in Endometrial and Endocervical Curettings in a Patient With Recurrent Vulvar Paget's Disease. Clayton EF, Rubin SC, Dumoff KL. Int J Surg Pathol. 2014 Jun;22(4):374-7. doi: 10.1177/1066896913498819. Epub 2013 Aug 5. PMID: 23918905
Phase I/II randomized trial of dendritic cell vaccination with or without cyclophosphamide for consolidation therapy of advanced ovarian cancer in first or second remission. Chu CS, Boyer J, Schullery DS, Gimotty PA, Gamerman V, Bender J, Levine BL, Coukos G, Rubin SC, Morgan MA, Vonderheide RH, June CH. Cancer Immunol Immunother. 2012 May;61(5):629-41. doi: 10.1007/s00262-011-1081-8. Epub 2011 Oct 22. PMID: 22021066
A high response rate to liposomal doxorubicin is seen among women with BRCA mutations treated for recurrent epithelial ovarian cancer. Adams SF, Marsh EB, Elmasri W, Halberstadt S, Vandecker S, Sammel MD, Bradbury AR, Daly M, Karlan B, Rubin SC. Gynecol Oncol. 2011 Dec;123(3):486-91. doi: 10.1016/j.ygyno.2011.08.032. Epub 2011 Sep 25. PMID: 21945552
Tissue-based immune monitoring II: multiple tumor sites reveal immunologic homogeneity in serous ovarian carcinoma. Hagemann AR, Hagemann IS, Cadungog M, Hwang WT, Patel P, Lal P, Hammond R, Gimotty PA, Chu CS, Rubin SC, Birrer MJ, Powell DJ Jr, Feldman MD, Coukos G. Cancer Biol Ther. 2011 Aug 15;12(4):367-77. Epub 2011 Aug 15. PMID: 21785280
Tissue-based immune monitoring I: tumor core needle biopsies allow in-depth interrogation of the tumor microenvironment. Hagemann AR, Cadungog M, Hagemann IS, Hammond R, Adams SF, Chu CS, Rubin SC, Zhang L, Addya K, Birrer MJ, Gimotty PA, Coukos G. Cancer Biol Ther. 2011 Aug 15;12(4):357-66. Epub 2011 Aug 15. PMID: 21785264
Clinical predictors of bevacizumab-associated gastrointestinal perforation. Tanyi JL, McCann G, Hagemann AR, Coukos G, Rubin SC, Liao JB, Chu CS. Gynecol Oncol. 2011 Mar;120(3):464-9. doi: 10.1016/j.ygyno.2010.11.009. Epub 2010 Dec 17. PMID: 21168199
Vaginal intraepithelial neoplasia (VAIN) after radiation therapy for gynecologic malignancies: a clinically recalcitrant entity. Liao JB, Jean S, Wilkinson-Ryan I, Ford AE, Tanyi JL, Hagemann AR, Lin LL, McGrath CM, Rubin SC. Gynecol Oncol. 2011 Jan;120(1):108-12. doi: 10.1016/j.ygyno.2010.09.005. PMID: 20937524
Additional Publications
Clinical Locations
Primary Location
Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111
Chief, Division of Gynecologic Oncology
Professor, Department of Surgical Oncology
Treatment Focus
Surgery and chemotherapy for all gynecologic cancers; minimally invasive surgery for gynecologic cancers, precancerous conditions and benign gynecologic conditions
Key Awards
|
| Gynecologic Oncology |
Treatment Philosophy
I joined Fox Chase Cancer Center in 2014 as chief of the Division of Gynecologic Oncology. I spent the early part of my medical career at Memorial Sloan-Kettering Cancer Center in New York and the Hospital of the University of Pennsylvania, where I was chief of gynecologic oncology. As a gynecologic oncologist, I have extensive training and experience in surgery (including minimally invasive) for gynecologic cancers and for complex benign gynecologic conditions. I also provide the full range of chemotherapy options for gynecologic cancers, giving my patients the continuity of care that comes with multimodal cancer care.
I am delighted to be practicing at Fox Chase, where I offer patients state-of-the-art care, including innovative clinical trials, in a caring, compassionate environment, with all the support services that come from an NCI-designated Comprehensive Cancer Center.
Education
Educational Background
- Fellow, Gynecologic Oncology, Hospital of the University of Pennsylvania, Philadelphia, PA, 1982
- Resident, Obstetrics & Gynecology, Hospital of the University of Pennsylvania, Philadelphia, PA, 1980
- MD, University of Pennsylvania School of Medicine, Philadelphia, PA, 1976
Certifications
- American Board of Obstetrics and Gynecology
- American Board of Obstetrics and Gynecology, Division of Gynecologic Oncology
Memberships
- American Association of Gynecologic Laparoscopists
- American College of Obstetricians and Gynecologists
- American College of Surgeons
- American Federation for Clinical Research
- American Gynecological and Obstetrical Society
- American Radium Society
- American Society of Clinical Oncology
- American Society for Colposcopy and Cervical Cytology
- Association of Professors of Gynecology and Obstetrics
- Society of Gynecologic Oncologists
- Society for Gynecologic Investigation
- Society of Pelvic Surgeons
- Society of Surgical Oncology
- International Gynecologic Cancer Society
- European Society of Gynecological Oncology
- Felix Rutledge Society
- New York Academy of Sciences
- New York Obstetrical Society
- New York Gynecological Society
- Obstetrical Society of Philadelphia
- Philadelphia Colposcopy Society
- Philadelphia College of Physicians
- Mid-Atlantic Gynecologic Oncology Society
Honors & Awards
- Philadelphia Magazine Top Doctors, 1993-20
- Best Doctors in America® , 2014, 2019-2020
- America’s Top Doctors®, 2015-17
- MA honoris causa, University of Pennsylvania, 1994
- Presidential Award, Society of Gynecologic Oncologists, 1993
- Boyer Award for Clinical Investigation, Memorial Sloan-Kettering Cancer Center, 1990
- Clinical Oncology Career Development Award, American Cancer Society, 1987-90
- Chief Resident's Teaching Award, Medical College of Pennsylvania, 1983
- Clinical Fellow, American Cancer Society, 1980-82
Research Profile
Research Interests
- Clinical trials and innovative therapies for gynecologic cancers
Publications
Selected Publications
Resilience, Positive Coping, and Quality of Life Among Women Newly Diagnosed With Gynecological Cancers. Manne SL, Myers-Virtue S, Kashy D, Ozga M, Kissane D, Heckman C, Rubin SC, Rosenblum N. Cancer Nurs. 2015 Sep-Oct;38(5):375-82. doi: 10.1097/NCC.0000000000000215.
Correlation of pelvic magnetic resonance imaging diagnosis with pathology for indeterminate adnexal masses. Haggerty AF, Hagemann AR, Chu C, Siegelman ES, Rubin SC. Int J Gynecol Cancer. 2014 Sep;24(7):1215-21. doi: 10.1097/IGC.0000000000000203. PMID: 25153677
Risk factors for GI adverse events in a phase III randomized trial of bevacizumab in first-line therapy of advanced ovarian cancer: A Gynecologic Oncology Group Study. Burger RA, Brady MF, Bookman MA, Monk BJ, Walker JL, Homesley HD, Fowler J, Greer BE, Boente M, Fleming GF, Lim PC, Rubin SC, Katsumata N, Liang SX. J Clin Oncol. 2014 Apr 20;32(12):1210-7. doi: 10.1200/JCO.2013.53.6524. Epub 2014 Mar 17. PMID: 24637999
Paget Cells in Endometrial and Endocervical Curettings in a Patient With Recurrent Vulvar Paget's Disease. Clayton EF, Rubin SC, Dumoff KL. Int J Surg Pathol. 2014 Jun;22(4):374-7. doi: 10.1177/1066896913498819. Epub 2013 Aug 5. PMID: 23918905
Phase I/II randomized trial of dendritic cell vaccination with or without cyclophosphamide for consolidation therapy of advanced ovarian cancer in first or second remission. Chu CS, Boyer J, Schullery DS, Gimotty PA, Gamerman V, Bender J, Levine BL, Coukos G, Rubin SC, Morgan MA, Vonderheide RH, June CH. Cancer Immunol Immunother. 2012 May;61(5):629-41. doi: 10.1007/s00262-011-1081-8. Epub 2011 Oct 22. PMID: 22021066
A high response rate to liposomal doxorubicin is seen among women with BRCA mutations treated for recurrent epithelial ovarian cancer. Adams SF, Marsh EB, Elmasri W, Halberstadt S, Vandecker S, Sammel MD, Bradbury AR, Daly M, Karlan B, Rubin SC. Gynecol Oncol. 2011 Dec;123(3):486-91. doi: 10.1016/j.ygyno.2011.08.032. Epub 2011 Sep 25. PMID: 21945552
Tissue-based immune monitoring II: multiple tumor sites reveal immunologic homogeneity in serous ovarian carcinoma. Hagemann AR, Hagemann IS, Cadungog M, Hwang WT, Patel P, Lal P, Hammond R, Gimotty PA, Chu CS, Rubin SC, Birrer MJ, Powell DJ Jr, Feldman MD, Coukos G. Cancer Biol Ther. 2011 Aug 15;12(4):367-77. Epub 2011 Aug 15. PMID: 21785280
Tissue-based immune monitoring I: tumor core needle biopsies allow in-depth interrogation of the tumor microenvironment. Hagemann AR, Cadungog M, Hagemann IS, Hammond R, Adams SF, Chu CS, Rubin SC, Zhang L, Addya K, Birrer MJ, Gimotty PA, Coukos G. Cancer Biol Ther. 2011 Aug 15;12(4):357-66. Epub 2011 Aug 15. PMID: 21785264
Clinical predictors of bevacizumab-associated gastrointestinal perforation. Tanyi JL, McCann G, Hagemann AR, Coukos G, Rubin SC, Liao JB, Chu CS. Gynecol Oncol. 2011 Mar;120(3):464-9. doi: 10.1016/j.ygyno.2010.11.009. Epub 2010 Dec 17. PMID: 21168199
Vaginal intraepithelial neoplasia (VAIN) after radiation therapy for gynecologic malignancies: a clinically recalcitrant entity. Liao JB, Jean S, Wilkinson-Ryan I, Ford AE, Tanyi JL, Hagemann AR, Lin LL, McGrath CM, Rubin SC. Gynecol Oncol. 2011 Jan;120(1):108-12. doi: 10.1016/j.ygyno.2010.09.005. PMID: 20937524
Additional Publications
Related Articles
36 PATIENT COMMENTS
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5.0
May 21, 2021
Always very good experience. I am very lucky to have Dr. Rubin as my oncologist.
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5.0
May 10, 2021
very satisfied with my care.
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5.0
March 20, 2021
I feel satisfied with the assistance of services that I receive with you.
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5.0
March 20, 2021
Dr. Rubin is an excellent doctor. [...] is wonderful. would recommend both highly!
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5.0
March 12, 2021
Always a pleasant experience. Dr. Rubin and his staff are the best! They are all truly appreciated!
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5.0
March 10, 2021
Dr. Rubin is an exceptional, caring, and empathetic physician and an expert in his field.
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5.0
March 08, 2021
Dr. Rubin [...] & [...] were very concerned that I was sick from my medication. Sent me for additional fluids & potassium. When I came home I felt better.
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5.0
February 19, 2021
Only negative experience was length of time it took to get test results.
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5.0
January 22, 2021
Thank you.
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5.0
January 14, 2021
Dr. Rubin & nurse [...] are the best!
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5.0
December 26, 2020
Dr. Rubin and his team are simply the best! Top notch care with access to multiple treatment plans, compassion, kindness and honesty. If you need a gynecological oncologist, this is the doctor and team!
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4.0
December 18, 2020
[...] very good.
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5.0
November 30, 2020
I have been seeing Dr. Stephen Rubin for 18 years. He saved my life. I am forever grateful to him.
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3.0
November 25, 2020
I am very nervous about the tests that were ordered and have not had them to date. I felt that since it did not appear that I have cancer. I am not important to the doctor.
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5.0
November 25, 2020
Always a great experience! [...] Happy my CT scan was good! Dr. Rubin - super nurse [...] super.
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5.0
November 11, 2020
everything was good [...]
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5.0
November 03, 2020
Best hospital I have ever been in for surgery. Felt very confident about Dr. Rubin. Everyone on staff was excellent from the doctors down to the hospital cleaning staff.
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5.0
October 30, 2020
my visit to Fox Chase was very easy and successful. the nursing staff receptionist and the doctor especially the doctor is very good at handling my situation explaining that to me making me feel at ease. I greatly all of their understanding.
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5.0
October 30, 2020
The nurse navigator [...] was very nice and helpful. Dr. Rubin was very caring.
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5.0
October 02, 2020
From my first phone call to schedule appointment w/Dr. Stephen Rubin. I have been so over-the-top impressed w/my visits to Fox Chase. I have raved about "everyone" I came contact with from sign in pre-admission. Pre op dr. visit, transporter, post OB, etc., etc!!
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