Jessica Karen Wong, MD, MEng

Dr. Jessica Wong

Clinical Locations

Primary Location

Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111


Assistant Professor, Department of Radiation Oncology
Assistant Director, Radiation Oncology Residency and Fellowship Training Program

Treatment Focus

Stereotactic Body Radiation Therapy (SBRT), Intensity Modulated Radiation Therapy (IMRT), Hypofractionated Radiation Therapy, High Dose Rate Prostate Brachytherapy, Anal Cancer

Key Awards

RSNA Roentgen Resident/Fellow Research Award 2019

Treatment Philosophy

I chose to join the Radiation Oncology faculty at Fox Chase after completing my training here because I believe that cancer is best treated in a multidisciplinary setting with the highest standard of clinical care. Here, cancer patients receive outstanding, compassionate treatment delivered with state of the art technology. I strive to maintain strong relationships with my patients and work with them to develop personalized treatment plans for their individual needs. I particularly enjoy our multi-disciplinary approach, as I feel that much more can be accomplished when people of different backgrounds and expertise work together on a common goal.

My primary treatment site is genitourinary malignancies, where I treat patients with both external beam radiation and brachytherapy. I am particularly interested in Prostate High Dose Rate (HDR) Brachytherapy which can reduce toxicity for certain patients while maintaining excellent cancer control. Prostate cancer has also been the focus of my academic interests and I have multiple active clinical and translational studies, including a national study comparing moderately-hypofractionated intensity modulated radiation therapy (IMRT) and proton radiation therapy.

After earning my Bachelor of Science in Chemical-Biological Engineering at the Massachusetts Institute of Technology and a Master’s of Engineering in Biomedical Engineering through the Harvard-MIT Division of Health Science and Technology, I attended medical school at the University of Tennessee. I believe the combination of my science and engineering background with my clinical training gives me a unique perspective to pursue clinical and translational research. Having a strong science background allows me to determine what scientific investigations are feasible and having a strong clinical background allows me to ensure that experiments are clinically relevant, allowing for the most immediate impact on patient care. I seek to further the understanding of radiation’s interaction with the body to improve treatment techniques and develop novel cancer treatments.

In addition to quality patient care and cutting-edge research, I also enjoy radiation oncology education and mentorship. I am active in the American Society for Radiation Oncology (ASTRO), Society of Women in Radiation Oncology (SWRO), American Brachytherapy Society (ABS), Association for Directors of Radiation Oncology Programs (ADROP), and Radiation Oncology Education Collaborative Study Group (ROECSG). I am proud to serve as the Assistant Director of our radiation oncology residency program and fellowship training program as our talented medical students, residents, and fellows are the future of our field.

Education and Training

Educational Background

  • Chief Resident, Fox Chase Cancer Center, Philadelphia, PA, 2018-2019
  • Resident, Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, 2016–2020
  • Resident, Preliminary Medicine, University of Tennessee, Memphis, TN, 2016
  • MD, University of Tennessee College of Medicine, Memphis, TN, 2015
  • MEng Biomedical Engineering, Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA, 2011
  • BS, Chemical-Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 2010


  • American Society for Radiation Oncology (ASTRO)
  • American Brachytherapy Society (ABS)
  • Association for Directors of Radiation Oncology Programs (ADROP)
  • Radiation Oncology Education Collaborative Study Group (ROECSG)
  • Society of Women in Radiation Oncology (SWRO)

Honors & Awards

  • RSNA Roentgen Resident/Fellow Research Award 2019
Research Profile

Research Interests

Prostate Cancer, High Dose Rate Brachytherapy, Translational Research, Radio-Immunotherapy


Selected Publications

Avkshtol V, Ruth KJ, Ross EA, Hallman MA, Greenberg RE, Price RA Jr, Leachman B, Uzzo RG, Ma C, Chen D, Geynisman DM, Sobczak ML, Zhang E, Wong JK, Pollack A, Horwitz EM. Ten-Year Update of a Randomized, Prospective Trial of Conventional Fractionated Versus Moderate Hypofractionated Radiation Therapy for Localized Prostate Cancer. J Clin Oncol. 2020 May 20;38(15):1676-1684. PMID: 32119599

Wong JK, Handorf E, Lee D, Jain R, Zhang E, Cooper HS, Farma JM, Dotan E, Meyer JE. Toxicity and outcomes in older versus younger patients treated with trimodality therapy for locally advanced rectal cancer. J Geriatr Oncol. 2020 May 4; PMID: 32381438.

Wong JK, Shaikh T, DeMora L, Zhang E, Borghaei H, Hayes SB, Kumar S, Meyer JE, Hallman MA. Predictors of Distant Recurrence Following Stereotactic Body Radiation Therapy for Stage I Non-Small Cell Lung Cancer. Am J Clin Oncol. 2020 Apr;43(4):243-248.  PMID: 31913907

Pai Panandiker AS, Wong JK, Nedelka MA, Wu S, Gajjar A, Broniscer A. (2014), Effect of time from diagnosis to start of radiotherapy on children with diffuse intrinsic pontine glioma. Pediatr Blood Cancer. 2014, 61 (1180-1183). PMID: 24482196

Additional Publications




Our Patient Satisfaction Rating is an average of all responses to care provider related questions from our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more.


5.0 / 5.0


  • 4.9
  • 4.9
  • 5.0
  • 5.0
  • 5.0


  • 5.0
    July 06, 2021
    I am very grateful and happy to come to Fox Chase Cancer Center thank you so much Dr. Wong & [...].
  • 5.0
    July 02, 2021
    GOOD EXPERIENCE; during [...] initial visit with Dr. Wong. Also spoke with Dr. Wong's associate - [...]. Both doctors very helpful in answering questions, etc.
  • 5.0
    June 07, 2021
    I had a good experience during my visit. Dr. Wong was very passionate and knowledgeable.
  • No Star Ratings Available May 29, 2021
    No problems - clearly explained
  • 5.0
    May 25, 2021
    I had a very good experience with entire staff Dr. Wong is truly exceptional! Could not have better! Doctor.
  • 5.0
    May 19, 2021
    So far, excellent experience.
  • No Star Ratings Available April 30, 2021
    Dr. Jessica Wong is the best.
  • 5.0
    April 15, 2021
    Dr. Wong and her entire staff are FANTASTIC!
  • No Star Ratings Available March 30, 2021
    [...] and Dr. Wong both took time to explain my treatment options, and I especially appreciated receiving their notes about our session in my patient portal.
  • 5.0
    March 17, 2021
    Everyone was friendly and professional.
  • No Star Ratings Available January 15, 2021
    awesome experience
  • No Star Ratings Available November 22, 2020
    I thought that Dr. Wong was great. She seems very intelligent and competent. She was very friendly and listened carefully to all of my questions and concerns. She clearly cares about her patients and I am looking forward to her overseeing my treatment.
  • 5.0
    November 10, 2020
    My entire experience with Dr. Wong, her staff and the techs in radiation, has been OUTSTANDING!!
  • No Star Ratings Available October 25, 2020
    very personal experience

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