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Joan Font-Burgada, PhD

Joan Font-Burgada, PhD
About

Assistant Professor

Research Program

Education and Training

Educational Background

  • PhD in Genetics, University of Barcelona, Barcelona, 2010 
  • MS in Genetics, University of Barcelona, Barcelona, 2004 
  • BS in Biology, University of Barcelona, Barcelona, 2000

Honors & Awards

  • 2001 Predoctoral fellowship from Spanish Ministry of Education
  • 2005 Predoctoral fellowship. Scientific Parc of Barcelona (PCB)
  • 2010 Summa cum laude distinction of Doctoral Thesis
  • 2012 California Institute for Regenerative Medicine Postdoctoral Training Grant
  • 2015 K99/R00 NIH Pathway to Independence award
  • 2015 Hertzberg-Schechter Prize for Stem Cell Research
Research Profile

Research Program

Lab Overview

Lab Staff

Lauren Strathearn, PhD

Postdoctoral Associate

Room: P3123
215-728-5689

Yuanguangyan Zhang

Visiting Scientist

Room: P3123
215-728-5689

Marcos García Teneche

Graduate Student

Room: P3123
215-728-5689

Charlie Hewett

Technical Staff

Room: P3123
215-728-5689
Publications

Selected Publications

Strathearn LS, Stepanov AI, Font-Burgada J. "Inflammation in Primary and Metastatic Liver Tumorigenesis-Under the Influence of Alcohol and High-Fat Diets".
Nutrients 2020 Mar 27;12(4). pii:E933. doi: 10.3390/nu12040933. PubMed

Beauchemin L, Slifker M, Rossell D, Font-Burgada J. "Characterizing MHC-I Genotype Predictive Power for Oncogenic Mutation Probability in Cancer Patients".
Methods Mol Biol. 2020;2131:185-198. doi: 10.1007/978-1-0716-0389-5_8. PubMed

Wong J, Garcia-Carbonell R, Zelic M, Ho SB, Boland BS, Yao SJ, Desai SA, Das S, Planell N, Harris PA, Font-Burgada J, Taniguchi K, Bertin J, Salas A, Pasparakis M, Gough PJ, Kelliher M, Karin M, Guma M. "RIPK1 Mediates TNF-Induced Intestinal Crypt Apoptosis During Chronic NF-KB Activation".
Cell Mol Gastroenterol Hepatol. 2020;9(2):295-312. doi: 10.1016/j.jcmgh.2019.10.002. Epub2019 Oct 10. PubMed

de Prisco, N, Stout E, Font-Burgada J. "Specific labeling and lineage tracing of periportal hepatocytes using two-step genetic recombination".
Methods Mol Biol. 2019;1905:59-70. doi: 10.1007/978-1-4939-8961-4_6. PubMed

Marty P R, Thompson WK, Salem RM, Font-Burgada J, Zanetii M, Carter, H. "Evolutionary pressure against MHC class II binding  cancer mutations."
Cell. 2018 Oct 4;175(2):416-428.e13. doi: 10.1016/j.cell.2018.08.048. Epub 2018 Sep 20. Erratum in: Cell. 2018 Dec 13;175(7):1991. PMID: 30245014. PubMed. Correction.

Dow M, Pyke RM, Tsui BY, Alexandrov LB, Nakagawa H, Taniguchi K, Seki E, Harismendy O, Shalapour S, Karin M#, Carter H#, Font-Burgada J#. “Intergrative genomic analysis of mouse and human hepatocellular carcinoma”. Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):E9879-E9888. doi:10.1073/pnas.1811029115. (# co-corresponding authors). PubMed

Marty R, de Prisco N, Carter H, Font-Burgada J. MHC-I genotype drives early immune selection of oncogenic mutations. Molecular and Cellular Oncology, 5(2), 2018. PubMed

Marty R, Kaabinejadian S, Rossell D, Slifker M, van der Haar J, Engin HB, de Prisco N, Ideker T, Hildebrand WH, Font-Burgada J#,*, Carter H*. “ MHC-I genotype restricts the oncogenic mutational landscape”.
Cell. 2017 Nov 30;171(6):1272-1283.e15. doi: 10.1016/j.cell.2017.09.050. (#corresponding author, *equally contributed). PMID: 29107334  Highlighted in Nature Reviews Immunology (2017; 17, 729), Nature Reviews Clinical Oncology (2018; 15, 5) and Cell (2017; 171(6):1252–1253). PubMed

Umemura A, He F, Taniguchi K, Nakagawa H, Yamachika S, Font-Burgada J, Zhong Z, Subramaniam S, Raghunandan S, Duran A, Linares JF, Reina-Campos M, Umemura S, Valasek MA, Seki E, Yamaguchi K, Koike K, Itoh Y, Diaz-Meco MT, Moscat J, Karin M. “p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells”.
Cancer Cell. 2016 May 19; doi: 10.1016/j.ccell.2016.04.006. [Epub ahead of print]. PubMed

Font-Burgada J, Sun B, Karin M. “Obesity and cancer: The oil that feeds the flame”.
Cell Metabolism. 2016 Jan 12; 23(1):48–62. doi: 10.1016/j.cmet.2015.12.015. PubMed ... Expand

Additional Publications

Dr. Font-Burgada on PubMed

This Fox Chase professor participates in the Undergraduate Summer Research Fellowship
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