Efrat Dotan, MD

Efrat Dotan, MD
91 Patient Satisfaction Ratings

This Fox Chase professor participates in the Undergraduate Summer Research Fellowship
Learn more about Research Volunteering.

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Clinical Locations

Chief, Division of Gastrointestinal Medical Oncology

Associate Professor, Department of Hematology/Oncology

Associate Director, Hematology/Oncology Fellowship Training Program

NCCN, Chair of the Older Adult Oncology Panel

NCCN, Pancreatic Adenocarcinoma Panel Member

Treatment Focus

Gastrointestinal cancers; Geriatric Oncology

Language(s) Other than English

  • Hebrew

Treatment Philosophy

I specialize in treatment of patients with gastrointestinal cancers with various chemotherapies. My goal is to provide each patient with cutting-age therapy for their cancer, and the supportive care necessary for tolerating treatment. I am specifically interested in caring for older adults with gastrointestinal cancers, while focusing on other factors that are not related to their cancer and complicate their care.

Follow on Twitter @efratdotan

Educational Background

  • Fellow & Chief Fellow, Hematology/Oncology, Fox Chase Cancer Center, Philadelphia, PA
  • Resident & Chief Resident, Internal Medicine, Lenox Hill Hospital, New York, NY, 2007
  • Resident, Internal Medicine, Lenox Hill Hospital, New York, NY, 2006
  • MD, Technion, Israel Institute of Technology, Israel, 2002


  • American Board of Internal Medicine
  • Board Certification in Hematology and Medical Oncology 


  • National Comprehensive Cancer Network (NCCN)
    • Cancer-Related Fatigue Panel
    • Occult Primary Panel
    • Older Adult Oncology Panel
  • American Society of Clinical Oncology (ASCO)
  • International Society of Geriatric Oncology (SIOG)
  • Cancer and Aging Research Group (CARG)
  • Eastern Cooperative Oncology Group (ECOG)
  • American Medical Association (AMA) 

Honors & Awards

  • AMGEN Fellowship Grant 2009;
  • American College of Physician (ACP): Associate Research Competition Award

Shelby Hurley

  • Breast Cancer

I remember lying on the operating table before surgery, worrying about what was going to happen next. My breast was trying to kill me but it had still been difficult to make the decision to undergo a mastectomy.


Robert Evans

In August 2015, Robert Evans, 70, went to a local suburban Philadelphia hospital to have surgery for a ruptured bowl after experiencing extreme pain in his abdomen. During the surgery, doctors decided it was best to remove his appendix because it was enflamed and interfering with the procedure. This was a fairly routine procedure, and a cancer diagnosis was far from Robert’s mind. When Robert learned he had cancer of the appendix, he sought a second opinion at Fox Chase Cancer Center, where he later underwent surgery. "I was, and remain today, very impressed by Fox Chase," Robert said. "My stay there was unlike any other hospital stay I have had. The quietness was absolutely incredible, and it was a very calming environment. From the person cleaning my room to the top-level nurses and physicians, everyone was spectacular."


Darryl Hall

  • Colorectal Cancer

When Darryl Hall was diagnosed with colon cancer, he was referred to a surgeon at a local hospital. After two colonoscopies and exploratory surgery, Darryl still felt he had no solid answers regarding his condition. He decided to seek a second opinion from a specialist at Fox Chase Cancer Center. Darryl had a completely different experience at Fox Chase, where he underwent surgery and chemotherapy. "I encourage other people like me to get a second opinion if they are not happy with their current treatment plan," he said. "Both my wife and I received the best of care at Fox Chase. We are grateful to our doctors, and we recommend Fox Chase to anyone needing cancer care. Today we are both doing well and can enjoy the time we spend together and with our five grandchildren."


Frances Hatalovsky

  • GIST (Gastrointestinal Stromal Tumor)

When Frances Hatalovsky was diagnosed with metastatic carcinoid cancer at age 74, she sought treatment at Fox Chase Cancer Center. In January 2006, she had surgery to remove the cancerous tissue from her colon, small intestine, ovaries, and liver. The surgery was successful, and Frances returned to work two months later. "I will never forget how patient, kind, compassionate, and attentive the Fox Chase staff was when they first met with me and my husband, John," she said. "They reviewed my records and test results, showed us my X-rays, and pointed out exactly where the cancer was located and how far it had spread. They asked me how I wanted to proceed given the diagnosis, and they gave me the confidence I needed to know I could beat the cancer."


Research Interests

  • Clinical trials of novel treatments for gastrointestinal cancers.
  • Drug Development
  • Clinical trial specific to older cancer patients

Selected Publications

Seedor R.S., Meeker C.R., Lewis B., Handorf E.A., Filchner K.A., Varadarajan R., Hensold J., Padmanabhan A., Negin B., Blankstein K., Chawla N.R., Song W., Epstein J., Winn J., Goldstein L.J., Dotan E., Prospective comparison of geriatric assessment and provider's assessment of older adults with metastatic breast cancer in the community. Oncologist. 27(2): E133-E141, 2022. <Go to ISI>://WOS:000764264500011.

Winer A., Handorf E.,Dotan E., Dosing schedules of gemcitabine and nab-paclitaxel for older adults with metastatic pancreatic cancer. Jnci Cancer Spectrum. 5(5): pkab074, 2021.PMC8438244. https://www.ncbi.nlm.nih.gov/pubmed/34532641.

Dotan E. The Future of Geriatric Oncology Research: Moving Toward Interventions and Objective Biomarkers of Aging. JNCCN September 2021, 19(9):1111-1113. DOI

Vijayvergia N, Dotan E, Devarajan K, et al. Patterns of care and outcomes of older versus younger patients with metastatic pancreatic cancer: A Fox Chase Cancer Center Experience. J Geriatr Oncol. 2015; S1879-4068. [Epub ahead of print]. PubMed

Dotan E, Li T, Hall M, Meropol N, Beck R, Wong YN. Oncologists’ Response to New Data Regarding the Use of Epidermal Growth Factor Receptor Inhibitors in Colorectal Cancer. JOP. September 2014 10(5): 308-14.  PubMed

McCleary N, Dotan E, Browner I. Refining Chemotherapy Approach for Older Patients with Colon Cancer. J Clin Oncol, August 2014; 32: 2570-2580. PubMed

Dotan E, Devarajan K, D’Silva JA, Beck A, Kloth D, Cohen J S, Denlinger C. Patterns of use and tolerance of anti-epidermal growth factor receptor antibodies among older adults with metastatic colorectal cancer. Clinical Colorectal Cancer. September 2014; 13(3):192-8. PubMed

Dotan E, Meropol N, Zhu F, Bove B, Cai K, Godwin A, Golemis A, Astsaturov I, Cohen S. Increased Aurora kinase A gene copy number is associated with improved prognosis and response to chemotherapy in patients with metastatic colorectal cancer. British Journal of Cancer. 2012 Feb 14;106(4):748-55   PubMed

Dotan E, Browner I, Hurria A, Denlinger C: Challenges in the management of elderly patients with colon cancer. JNCCN February 2012, 10(2):213-24  PubMed

Dotan E, Meropol J N, Burtness B, Denlinger C et al. A phase II study of capecitabine, oxaliplatin, and cetuximab with or without bevacizumab as front line therapy for metastatic colorectal cancer.  A Fox Chase Extramural Research Study. J Gastrointest Cancer, December 2012, 43(4), 562-569. PMCID: PMC340072  PubMed... Expand

Additional Publications

91 patient satisfaction reviews

Our Patient Satisfaction Rating is an average of all responses to care provider related questions from our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more.

Overall Rating

4.9 / 5.0

Ratings Breakdown

Gives easy to understand instruction
Explains in a way you understand
Listens carefully to you
Shows respect for what you say
Spends enough time with you

16 patient comments

  • 5.0
    March 6, 2022

    I was experiencing irregular heart beats and I was given a cardio gram as part of my visit.I have now seen a cardiologist .I really appreciate the concern of Dr Dotan and a resident whose name I don't recall taking the added steps to help calm me.

  • 5.0
    February 7, 2022

    I have stage four cancer- Dr. Dotan had to deliver some bad news, and did it well. Also, ordered tests STAT and has ideas for me!

  • 5.0
    November 18, 2021

    Wonderful experience. I look forward to seeing her again after my chemo is completed.

  • 5.0
    November 13, 2021

    So glad I came to Fox Chase. My care team is excellent, knowledgeable and very kind

  • 5.0
    October 22, 2021

    [...] My contact with Dr Dotan and her staff is for cancer care at Fox Chase. I have been extremely satisfied with everyone there With whom I have had contact

  • 5.0
    October 19, 2021

    Doc Efrat Dotan She is the best number 1.

  • 5.0
    October 9, 2021

    Very good experience with this doctor. She was very thorough and knowledgeable and caring.

  • No Star Ratings Available
    October 7, 2021

    Very helpful and informative

  • 5.0
    September 24, 2021

    The people at Fox Chase CC, especially Dr. Dotans office, are super stars.

  • 5.0
    July 27, 2021

    Having been diagnosed with cancer I was very scared and thought I would die. Dr Dotan treatments saved my life. I would recomend her to everyone.

  • 5.0
    June 24, 2021

    Absolutely best care!!!

  • 5.0
    June 21, 2021

    Nothing but exceptional - Very good experience.

  • 5.0
    February 19, 2021

    service is always excellent

  • 5.0
    February 3, 2021

    My experiences have been very good. Everyone is most kind & helpful.

  • No Star Ratings Available
    January 13, 2021

    she was very patient and allowed me to ask questions and take notes

  • 5.0
    January 11, 2021

    Very good.

This Fox Chase professor participates in the Undergraduate Summer Research Fellowship
Learn more about Research Volunteering.