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Efrat Dotan, MD

Clinical Locations

Primary Location

Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111

Assistant Professor

Assistant Program Director, Hematology/Oncology Fellowship Program 

Treatment Focus

Geriatric Oncology

Research Program

Language(s) Other than English

Hebrew

Treatment Philosophy

I specialize in treatment of patients with gastrointestinal cancers with various chemotherapies. My goal is to provide each patient with cutting age therapy for therapy for their cancer, and supportive care necessary for tolerating treatment. I am specifically interested in caring for older adults with gastrointestinal cancers, while focusing on other factors that are not related to their cancer and complicates their care.

Follow on Twitter @efratdotan

Educational Background

  • Fellow & Chief Fellow, Hematology-Oncology, Fox Chase Cancer Center, Philadelphia, PA
  • Resident & Chief Resident, Internal Medicine, Lenox Hill Hospital, New York, NY, 2007
  • Resident, Internal Medicine, Lenox Hill Hospital, New York, NY, 2006
  • MD, Technion, Israel Institute of Technology, Bruce Rappaport Faculty of Medicine, cum laude 2002

Certifications

  • American Board of Internal Medicine
  • Board Certification in Hematology and Medical Oncology 

Memberships

  • American Society of Clinical Oncology (ASCO)
  • International Society of Geriatric Oncology (SIOG)
  • Cancer and Aging Research Group (CARG)
  • Eastern Cooperative Oncology Group (ECOG)
  • American Medical Association (AMA) 

Honors & Awards

  • AMGEN Fellowship Grant 2009;
  • American College of Physician (ACP): Associate Research Competition Award

Frances Hatalovsky

GIST (Gastrointestinal Stromal Tumor)

Frances Hatalovsky

GIST (Gastrointestinal Stromal Tumor)

When Fran Hatalovsky turned 74 in 2006, she wasn’t even entertaining the idea of retirement. In fact, when she was told by her Fox Chase Cancer Center surgeon that carcinoid cancer had spread throughout her body, her main concern was whether she'd be able to return to work. Her surgeon assured her that he would do everything in his power to make it happen. Just two months after her surgeon performed a very complex procedure to remove the cancerous tissue that affected Fran's colon, small intestine, ovaries and liver, she was able to return to work and couldn't have been more pleased.

Research Program

Research Interests

  • Clinical trials of novel treatments for gastrointestinal cancers.
  • Drug Development
  • Clinical trial specific to older cancer patients

Selected Publications

Vijayvergia N, Dotan E, Devarajan K, et al. Patterns of care and outcomes of older versus younger patients with metastatic pancreatic cancer: A Fox Chase Cancer Center Experience. J Geriatr Oncol. 2015; S1879-4068. [Epub ahead of print]. PubMed

Dotan E, Li T, Hall M, Meropol N, Beck R, Wong YN. Oncologists’ Response to New Data Regarding the Use of Epidermal Growth Factor Receptor Inhibitors in Colorectal Cancer. JOP. September 2014 10(5): 308-14.  PubMed

McCleary N, Dotan E, Browner I. Refining Chemotherapy Approach for Older Patients with Colon Cancer. J Clin Oncol, August 2014; 32: 2570-2580. PubMed

Dotan E, Devarajan K, D’Silva JA, Beck A, Kloth D, Cohen J S, Denlinger C. Patterns of use and tolerance of anti-epidermal growth factor receptor antibodies among older adults with metastatic colorectal cancer. Clinical Colorectal Cancer. September 2014; 13(3):192-8. PubMed

Dotan E, Meropol N, Zhu F, Bove B, Cai K, Godwin A, Golemis A, Astsaturov I, Cohen S. Increased Aurora kinase A gene copy number is associated with improved prognosis and response to chemotherapy in patients with metastatic colorectal cancer. British Journal of Cancer. 2012 Feb 14;106(4):748-55   PubMed

Dotan E, Browner I, Hurria A, Denlinger C: Challenges in the management of elderly patients with colon cancer. JNCCN February 2012, 10(2):213-24  PubMed

Dotan E, Meropol J N, Burtness B, Denlinger C et al. A phase II study of capecitabine, oxaliplatin, and cetuximab with or without bevacizumab as front line therapy for metastatic colorectal cancer.  A Fox Chase Extramural Research Study. J Gastrointest Cancer, December 2012, 43(4), 562-569. PMCID: PMC340072  PubMed

Dotan E, Cohen S J. Challenges in the management of stage II colon cancer. Seminars in Oncology Aug 2011; 38(4): 511-20   PubMed

Dotan E, Cohen S J, Alpaugh K, Meropol N J. Circulating tumor cells: evolving evidence and future challenges. The oncologist, November 2009, 14(11): 1070-1082 PubMed

Additional Publications

My NCBI