This Fox Chase professor participates in the Undergraduate Summer Research Fellowship.
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Efrat Dotan, MD
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- Clinical Locations
- About
- Education and Training
- Patient Stories
- Research Profile
- Publications
- Ratings
Clinical Locations
Primary Location
Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111
About
Chief, Division of Gastrointestinal Medical Oncology
Associate Professor, Department of Hematology/Oncology
Associate Director, Hematology/Oncology Fellowship Training Program
NCCN, Chair of the Older Adult Oncology Panel
NCCN, Pancreatic Adenocarcinoma Panel Member
Specialties
Treatment Focus
Gastrointestinal cancers; Geriatric Oncology
Research Program
Language(s) Other than English
Hebrew
Treatment Philosophy
I specialize in treatment of patients with gastrointestinal cancers with various chemotherapies. My goal is to provide each patient with cutting-age therapy for their cancer, and the supportive care necessary for tolerating treatment. I am specifically interested in caring for older adults with gastrointestinal cancers, while focusing on other factors that are not related to their cancer and complicate their care.
Follow on Twitter @efratdotan
Education and Training
Educational Background
- Fellow & Chief Fellow, Hematology/Oncology, Fox Chase Cancer Center, Philadelphia, PA
- Resident & Chief Resident, Internal Medicine, Lenox Hill Hospital, New York, NY, 2007
- Resident, Internal Medicine, Lenox Hill Hospital, New York, NY, 2006
- MD, Technion, Israel Institute of Technology, Israel, 2002
Certifications
- American Board of Internal Medicine
- Board Certification in Hematology and Medical Oncology
Memberships
- National Comprehensive Cancer Network (NCCN)
- Cancer-Related Fatigue Panel
- Occult Primary Panel
- Older Adult Oncology Panel
- American Society of Clinical Oncology (ASCO)
- International Society of Geriatric Oncology (SIOG)
- Cancer and Aging Research Group (CARG)
- Eastern Cooperative Oncology Group (ECOG)
- American Medical Association (AMA)
Honors & Awards
- AMGEN Fellowship Grant 2009;
- American College of Physician (ACP): Associate Research Competition Award
Patient Stories
Shelby Hurley
Breast Cancer
Shelby Hurley
Breast Cancer
I remember lying on the operating table before surgery, worrying about what was going to happen next. My breast was trying to kill me but it had still been difficult to make the decision to undergo a mastectomy.
Robert Evans
Robert Evans
In August 2015, Robert Evans, 70, went to a local suburban Philadelphia hospital to have surgery for a ruptured bowl after experiencing extreme pain in his abdomen. During the surgery, doctors decided it was best to remove his appendix because it was enflamed and interfering with the procedure. This was a fairly routine procedure, and a cancer diagnosis was far from Robert’s mind. When Robert learned he had cancer of the appendix, he sought a second opinion at Fox Chase Cancer Center, where he later underwent surgery. "I was, and remain today, very impressed by Fox Chase," Robert said. "My stay there was unlike any other hospital stay I have had. The quietness was absolutely incredible, and it was a very calming environment. From the person cleaning my room to the top-level nurses and physicians, everyone was spectacular."
Darryl Hall
Colorectal Cancer
Darryl Hall
Colorectal Cancer
When Darryl Hall was diagnosed with colon cancer, he was referred to a surgeon at a local hospital. After two colonoscopies and exploratory surgery, Darryl still felt he had no solid answers regarding his condition. He decided to seek a second opinion from a specialist at Fox Chase Cancer Center. Darryl had a completely different experience at Fox Chase, where he underwent surgery and chemotherapy. "I encourage other people like me to get a second opinion if they are not happy with their current treatment plan," he said. "Both my wife and I received the best of care at Fox Chase. We are grateful to our doctors, and we recommend Fox Chase to anyone needing cancer care. Today we are both doing well and can enjoy the time we spend together and with our five grandchildren."
Frances Hatalovsky
GIST (Gastrointestinal Stromal Tumor)
Frances Hatalovsky
GIST (Gastrointestinal Stromal Tumor)
When Frances Hatalovsky was diagnosed with metastatic carcinoid cancer at age 74, she sought treatment at Fox Chase Cancer Center. In January 2006, she had surgery to remove the cancerous tissue from her colon, small intestine, ovaries, and liver. The surgery was successful, and Frances returned to work two months later. "I will never forget how patient, kind, compassionate, and attentive the Fox Chase staff was when they first met with me and my husband, John," she said. "They reviewed my records and test results, showed us my X-rays, and pointed out exactly where the cancer was located and how far it had spread. They asked me how I wanted to proceed given the diagnosis, and they gave me the confidence I needed to know I could beat the cancer."
Research Profile
Research Program
Research Interests
- Clinical trials of novel treatments for gastrointestinal cancers.
- Drug Development
- Clinical trial specific to older cancer patients
Publications
Selected Publications
Dotan E. The Future of Geriatric Oncology Research: Moving Toward Interventions and Objective Biomarkers of Aging. JNCCN September 2021, 19(9):1111-1113. DOI
Vijayvergia N, Dotan E, Devarajan K, et al. Patterns of care and outcomes of older versus younger patients with metastatic pancreatic cancer: A Fox Chase Cancer Center Experience. J Geriatr Oncol. 2015; S1879-4068. [Epub ahead of print]. PubMed
Dotan E, Li T, Hall M, Meropol N, Beck R, Wong YN. Oncologists’ Response to New Data Regarding the Use of Epidermal Growth Factor Receptor Inhibitors in Colorectal Cancer. JOP. September 2014 10(5): 308-14. PubMed
McCleary N, Dotan E, Browner I. Refining Chemotherapy Approach for Older Patients with Colon Cancer. J Clin Oncol, August 2014; 32: 2570-2580. PubMed
Dotan E, Devarajan K, D’Silva JA, Beck A, Kloth D, Cohen J S, Denlinger C. Patterns of use and tolerance of anti-epidermal growth factor receptor antibodies among older adults with metastatic colorectal cancer. Clinical Colorectal Cancer. September 2014; 13(3):192-8. PubMed
Dotan E, Meropol N, Zhu F, Bove B, Cai K, Godwin A, Golemis A, Astsaturov I, Cohen S. Increased Aurora kinase A gene copy number is associated with improved prognosis and response to chemotherapy in patients with metastatic colorectal cancer. British Journal of Cancer. 2012 Feb 14;106(4):748-55 PubMed
Dotan E, Browner I, Hurria A, Denlinger C: Challenges in the management of elderly patients with colon cancer. JNCCN February 2012, 10(2):213-24 PubMed
Dotan E, Meropol J N, Burtness B, Denlinger C et al. A phase II study of capecitabine, oxaliplatin, and cetuximab with or without bevacizumab as front line therapy for metastatic colorectal cancer. A Fox Chase Extramural Research Study. J Gastrointest Cancer, December 2012, 43(4), 562-569. PMCID: PMC340072 PubMed
Dotan E, Cohen S J. Challenges in the management of stage II colon cancer. Seminars in Oncology Aug 2011; 38(4): 511-20 PubMed
Dotan E, Cohen S J, Alpaugh K, Meropol N J. Circulating tumor cells: evolving evidence and future challenges. The oncologist, November 2009, 14(11): 1070-1082 PubMed
Additional Publications
Clinical Locations
Primary Location
Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111
Chief, Division of Gastrointestinal Medical Oncology
Associate Professor, Department of Hematology/Oncology
Associate Director, Hematology/Oncology Fellowship Training Program
NCCN, Chair of the Older Adult Oncology Panel
NCCN, Pancreatic Adenocarcinoma Panel Member
Treatment Focus
Gastrointestinal cancers; Geriatric Oncology
Research Program
Language(s) Other than English
Hebrew
Treatment Philosophy
I specialize in treatment of patients with gastrointestinal cancers with various chemotherapies. My goal is to provide each patient with cutting-age therapy for their cancer, and the supportive care necessary for tolerating treatment. I am specifically interested in caring for older adults with gastrointestinal cancers, while focusing on other factors that are not related to their cancer and complicate their care.
Follow on Twitter @efratdotan
Education
Educational Background
- Fellow & Chief Fellow, Hematology/Oncology, Fox Chase Cancer Center, Philadelphia, PA
- Resident & Chief Resident, Internal Medicine, Lenox Hill Hospital, New York, NY, 2007
- Resident, Internal Medicine, Lenox Hill Hospital, New York, NY, 2006
- MD, Technion, Israel Institute of Technology, Israel, 2002
Certifications
- American Board of Internal Medicine
- Board Certification in Hematology and Medical Oncology
Memberships
- National Comprehensive Cancer Network (NCCN)
- Cancer-Related Fatigue Panel
- Occult Primary Panel
- Older Adult Oncology Panel
- American Society of Clinical Oncology (ASCO)
- International Society of Geriatric Oncology (SIOG)
- Cancer and Aging Research Group (CARG)
- Eastern Cooperative Oncology Group (ECOG)
- American Medical Association (AMA)
Honors & Awards
- AMGEN Fellowship Grant 2009;
- American College of Physician (ACP): Associate Research Competition Award
Research Profile
Research Interests
- Clinical trials of novel treatments for gastrointestinal cancers.
- Drug Development
- Clinical trial specific to older cancer patients
Publications
Selected Publications
Dotan E. The Future of Geriatric Oncology Research: Moving Toward Interventions and Objective Biomarkers of Aging. JNCCN September 2021, 19(9):1111-1113. DOI
Vijayvergia N, Dotan E, Devarajan K, et al. Patterns of care and outcomes of older versus younger patients with metastatic pancreatic cancer: A Fox Chase Cancer Center Experience. J Geriatr Oncol. 2015; S1879-4068. [Epub ahead of print]. PubMed
Dotan E, Li T, Hall M, Meropol N, Beck R, Wong YN. Oncologists’ Response to New Data Regarding the Use of Epidermal Growth Factor Receptor Inhibitors in Colorectal Cancer. JOP. September 2014 10(5): 308-14. PubMed
McCleary N, Dotan E, Browner I. Refining Chemotherapy Approach for Older Patients with Colon Cancer. J Clin Oncol, August 2014; 32: 2570-2580. PubMed
Dotan E, Devarajan K, D’Silva JA, Beck A, Kloth D, Cohen J S, Denlinger C. Patterns of use and tolerance of anti-epidermal growth factor receptor antibodies among older adults with metastatic colorectal cancer. Clinical Colorectal Cancer. September 2014; 13(3):192-8. PubMed
Dotan E, Meropol N, Zhu F, Bove B, Cai K, Godwin A, Golemis A, Astsaturov I, Cohen S. Increased Aurora kinase A gene copy number is associated with improved prognosis and response to chemotherapy in patients with metastatic colorectal cancer. British Journal of Cancer. 2012 Feb 14;106(4):748-55 PubMed
Dotan E, Browner I, Hurria A, Denlinger C: Challenges in the management of elderly patients with colon cancer. JNCCN February 2012, 10(2):213-24 PubMed
Dotan E, Meropol J N, Burtness B, Denlinger C et al. A phase II study of capecitabine, oxaliplatin, and cetuximab with or without bevacizumab as front line therapy for metastatic colorectal cancer. A Fox Chase Extramural Research Study. J Gastrointest Cancer, December 2012, 43(4), 562-569. PMCID: PMC340072 PubMed
Dotan E, Cohen S J. Challenges in the management of stage II colon cancer. Seminars in Oncology Aug 2011; 38(4): 511-20 PubMed
Dotan E, Cohen S J, Alpaugh K, Meropol N J. Circulating tumor cells: evolving evidence and future challenges. The oncologist, November 2009, 14(11): 1070-1082 PubMed
Additional Publications
Related Articles
16 PATIENT COMMENTS
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5.0
March 06, 2022
I was experiencing irregular heart beats and I was given a cardio gram as part of my visit.I have now seen a cardiologist .I really appreciate the concern of Dr Dotan and a resident whose name I don't recall taking the added steps to help calm me.
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5.0
February 07, 2022
I have stage four cancer- Dr. Dotan had to deliver some bad news, and did it well. Also, ordered tests STAT and has ideas for me!
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5.0
November 18, 2021
Wonderful experience. I look forward to seeing her again after my chemo is completed.
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5.0
November 13, 2021
So glad I came to Fox Chase. My care team is excellent, knowledgeable and very kind
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5.0
October 22, 2021
[...] My contact with Dr Dotan and her staff is for cancer care at Fox Chase. I have been extremely satisfied with everyone there With whom I have had contact
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5.0
October 19, 2021
Doc Efrat Dotan She is the best number 1.
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5.0
October 09, 2021
Very good experience with this doctor. She was very thorough and knowledgeable and caring.
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No Star Ratings Available
October 07, 2021
Very helpful and informative
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5.0
September 24, 2021
The people at Fox Chase CC, especially Dr. Dotans office, are super stars.
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5.0
July 27, 2021
Having been diagnosed with cancer I was very scared and thought I would die. Dr Dotan treatments saved my life. I would recomend her to everyone.
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5.0
June 24, 2021
Absolutely best care!!!
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5.0
June 21, 2021
Nothing but exceptional - Very good experience.
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5.0
February 19, 2021
service is always excellent
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5.0
February 03, 2021
My experiences have been very good. Everyone is most kind & helpful.
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No Star Ratings Available
January 13, 2021
she was very patient and allowed me to ask questions and take notes
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5.0
January 11, 2021
Very good.
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