I specialize in treatment of patients with gastrointestinal cancers with various chemotherapies. My goal is to provide each patient with cutting-age therapy for their cancer, and the supportive care necessary for tolerating treatment. I am specifically interested in caring for older adults with gastrointestinal cancers, while focusing on other factors that are not related to their cancer and complicate their care.
I remember lying on the operating table before surgery, worrying about what was going to happen next. My breast was trying to kill me but it had still been difficult to make the decision to undergo a mastectomy.
In August 2015, Robert Evans, 70, went to a local suburban Philadelphia hospital to have surgery for a ruptured bowl after experiencing extreme pain in his abdomen. During the surgery, doctors decided it was best to remove his appendix because it was enflamed and interfering with the procedure. This was a fairly routine procedure, and a cancer diagnosis was far from Robert’s mind. When Robert learned he had cancer of the appendix, he sought a second opinion at Fox Chase Cancer Center, where he later underwent surgery. "I was, and remain today, very impressed by Fox Chase," Robert said. "My stay there was unlike any other hospital stay I have had. The quietness was absolutely incredible, and it was a very calming environment. From the person cleaning my room to the top-level nurses and physicians, everyone was spectacular."
When Darryl Hall was diagnosed with colon cancer, he was referred to a surgeon at a local hospital. After two colonoscopies and exploratory surgery, Darryl still felt he had no solid answers regarding his condition. He decided to seek a second opinion from a specialist at Fox Chase Cancer Center. Darryl had a completely different experience at Fox Chase, where he underwent surgery and chemotherapy. "I encourage other people like me to get a second opinion if they are not happy with their current treatment plan," he said. "Both my wife and I received the best of care at Fox Chase. We are grateful to our doctors, and we recommend Fox Chase to anyone needing cancer care. Today we are both doing well and can enjoy the time we spend together and with our five grandchildren."
When Frances Hatalovsky was diagnosed with metastatic carcinoid cancer at age 74, she sought treatment at Fox Chase Cancer Center. In January 2006, she had surgery to remove the cancerous tissue from her colon, small intestine, ovaries, and liver. The surgery was successful, and Frances returned to work two months later. "I will never forget how patient, kind, compassionate, and attentive the Fox Chase staff was when they first met with me and my husband, John," she said. "They reviewed my records and test results, showed us my X-rays, and pointed out exactly where the cancer was located and how far it had spread. They asked me how I wanted to proceed given the diagnosis, and they gave me the confidence I needed to know I could beat the cancer."
Clinical trials of novel treatments for gastrointestinal cancers.
Clinical trial specific to older cancer patients
Seedor R.S., Meeker C.R., Lewis B., Handorf E.A., Filchner K.A., Varadarajan R., Hensold J., Padmanabhan A., Negin B., Blankstein K., Chawla N.R., Song W., Epstein J., Winn J., Goldstein L.J., Dotan E., Prospective comparison of geriatric assessment and provider's assessment of older adults with metastatic breast cancer in the community. Oncologist. 27(2): E133-E141, 2022. <Go to ISI>://WOS:000764264500011.
Winer A., Handorf E.,Dotan E., Dosing schedules of gemcitabine and nab-paclitaxel for older adults with metastatic pancreatic cancer. Jnci Cancer Spectrum. 5(5): pkab074, 2021.PMC8438244. https://www.ncbi.nlm.nih.gov/pubmed/34532641.
Dotan E. The Future of Geriatric Oncology Research: Moving Toward Interventions and Objective Biomarkers of Aging. JNCCN September 2021, 19(9):1111-1113. DOI
Vijayvergia N, Dotan E, Devarajan K, et al. Patterns of care and outcomes of older versus younger patients with metastatic pancreatic cancer: A Fox Chase Cancer Center Experience. J Geriatr Oncol. 2015; S1879-4068. [Epub ahead of print]. PubMed
Dotan E, Li T, Hall M, Meropol N, Beck R, Wong YN. Oncologists’ Response to New Data Regarding the Use of Epidermal Growth Factor Receptor Inhibitors in Colorectal Cancer. JOP. September 2014 10(5): 308-14. PubMed
McCleary N, Dotan E, Browner I. Refining Chemotherapy Approach for Older Patients with Colon Cancer. J Clin Oncol, August 2014; 32: 2570-2580. PubMed
Dotan E, Devarajan K, D’Silva JA, Beck A, Kloth D, Cohen J S, Denlinger C. Patterns of use and tolerance of anti-epidermal growth factor receptor antibodies among older adults with metastatic colorectal cancer. Clinical Colorectal Cancer. September 2014; 13(3):192-8. PubMed
Dotan E, Meropol N, Zhu F, Bove B, Cai K, Godwin A, Golemis A, Astsaturov I, Cohen S. Increased Aurora kinase A gene copy number is associated with improved prognosis and response to chemotherapy in patients with metastatic colorectal cancer. British Journal of Cancer. 2012 Feb 14;106(4):748-55 PubMed
Dotan E, Browner I, Hurria A, Denlinger C: Challenges in the management of elderly patients with colon cancer. JNCCN February 2012, 10(2):213-24 PubMed
Dotan E, Meropol J N, Burtness B, Denlinger C et al. A phase II study of capecitabine, oxaliplatin, and cetuximab with or without bevacizumab as front line therapy for metastatic colorectal cancer. A Fox Chase Extramural Research Study. J Gastrointest Cancer, December 2012, 43(4), 562-569. PMCID: PMC340072 PubMed...Expand
Dotan E, Cohen S J. Challenges in the management of stage II colon cancer. Seminars in Oncology Aug 2011; 38(4): 511-20 PubMed
Dotan E, Cohen S J, Alpaugh K, Meropol N J. Circulating tumor cells: evolving evidence and future challenges. The oncologist, November 2009, 14(11): 1070-1082 PubMedCollapse
Our Patient Satisfaction Rating is an average of all responses to care provider related questions from our
nationally-recognized Press Ganey Patient Satisfaction Survey.
4.9 / 5.0
Gives easy to understand instruction
Explains in a way you understand
Listens carefully to you
Shows respect for what you say
Spends enough time with you
16 patient comments
March 6, 2022
I was experiencing irregular heart beats and I was given a cardio gram as part of my visit.I have now seen a cardiologist .I really appreciate the concern of Dr Dotan and a resident whose name I don't recall taking the added steps to help calm me.
February 7, 2022
I have stage four cancer- Dr. Dotan had to deliver some bad news, and did it well. Also, ordered tests STAT and has ideas for me!
November 18, 2021
Wonderful experience. I look forward to seeing her again after my chemo is completed.
November 13, 2021
So glad I came to Fox Chase. My care team is excellent, knowledgeable and very kind
October 22, 2021
[...] My contact with Dr Dotan and her staff is for cancer care at Fox Chase. I have been extremely satisfied with everyone there With whom I have had contact
October 19, 2021
Doc Efrat Dotan She is the best number 1.
October 9, 2021
Very good experience with this doctor. She was very thorough and knowledgeable and caring.
No Star Ratings Available
October 7, 2021
Very helpful and informative
September 24, 2021
The people at Fox Chase CC, especially Dr. Dotans office, are super stars.
July 27, 2021
Having been diagnosed with cancer I was very scared and thought I would die. Dr Dotan treatments saved my life. I would recomend her to everyone.
June 24, 2021
Absolutely best care!!!
June 21, 2021
Nothing but exceptional - Very good experience.
February 19, 2021
service is always excellent
February 3, 2021
My experiences have been very good. Everyone is most kind & helpful.
No Star Ratings Available
January 13, 2021
she was very patient and allowed me to ask questions and take notes