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Advisory Board

Margaret ("Peggy") Goodell, PhD

Professor and Chair
Department of Molecular and Cellular Biology
Director of the Stem Cells and Regenerative Medicine Center
Baylor College of Medicine

https://www.goodell-lab.com
https://www.bcm.edu/people-search/margaret-goodell-22230
https://www.bcm.edu/departments/molecular-and-cellular-biology

Margaret (“Peggy”) Goodell, PhD is Professor and Chair of the Department of Molecular and Cellular Biology, and Director of the Stem Cells and Regenerative Medicine Center, at Baylor College of Medicine, in Houston, Texas. Goodell’s research is focused on the mechanisms that regulate hematopoietic stem cells, and their dysregulation in malignancies, particularly DNA Methyltransferase 3A (DNMT3A). Goodell is a former president of the International Society for Experimental Hematology (2013). She is a recipient of the Damashek Prize from the American Society of Hematology (2012), the Edith and Peter O’Donnell Award in Medicine from TAMEST (2011) and the Tobias Award from the International Society for Stem Cell Research (2020), and she was elected to the National Academy of Medicine in 2019. Goodell is Chair of the Scientific Advisory Board of the Keystone Symposia and is a member of their Board of Directors. She has served on the editorial board of PLoS Biology, and as an Associated Editor of Blood, and currently serves on the editorial boards of Cell Stem Cell and Cancer Cell. Goodell directs a laboratory of about 15 trainees.

Sharon Y.R. Dent, PhD

Professor and Chair
Department of Epigenetics and Molecular Carcinogenesis
M.D. Anderson Cancer Center

https://www.mdanderson.org/research/departments-labs-institutes/labs/dent-laboratory.html

Sharon Y.R. Dent, PhD holds the Ruth Leggett Jones Distinguished Chair and serves as Chair of the Department of Epigenetics and Molecular Carcinogenesis at the University of Texas M.D. Anderson Cancer Center. Dr. Dent’s research exploits yeast, mouse, and human genetics to define functions of histone modifying enzymes. Her early discovery that a yeast corepressor complex repositions nucleosomes and recruits histone deacetylases to gene promoters created a new paradigm for transcriptional repression. Examples of other key findings include demonstration of the first methylation-phosphorylation regulatory switch in a non-histone protein; discovery that histone modifications, such as H2Bub, can drive modifications in non-histone proteins, thereby directly participating in signal transduction pathways; and uncovering unexpected functions for histone modifying enzymes in mitosis and telomere maintenance. Her more recent work revealed that the Gcn5 histone acetyltransferase is an essential co-activator for the Myc proto-oncogene and that a ubiquitin specific protease, USP22 that is over expressed in many human cancers is important for execution of multiple signaling pathways important for vasculogenesis. Dr. Dent was elected as Fellow for the American Association for the Advancement of Science in 2012.

C. David Allis, PhD

Joy and Jack Fishman Professor
Head, Laboratory of Chromatin Biology & Epigenetics
The Rockefeller University

https://lab.rockefeller.edu/allis

C. David Allis is currently the Joy and Jack Fishman Professor and head of the Laboratory of Chromatin Biology and Epigenetics at The Rockefeller University. Dr. Allis studies how the histone or epigenetic “code” serves as a fundamental regulatory mechanism for DNA templated processes. His studies have been addressing the impact that this encoded information has on development and disease. Dr. Allis has made seminal discoveries such as the discovery of the histone acetyltransferase, establishing the “histone code hypothesis”, identifying the first H3K4 methyl reader protein and most recently establishing a critical role for mutated histones in cancer (“oncohistones”). For these seminal discoveries, Dr. Allis has been awarded numerous awards such as the Gairdner Foundation International Award (2007), The Japan Prize (2014), Breakthrough Prize in Life Sciences (2015) and the Lasker Basic Medical Research Award (2018). Dr. Allis is a member of the American Academy of Arts and Sciences and National Academy of Sciences.

David Bjork

Research Advocate and Lung Cancer Survivor
Research Evangelist

https://www.researchevangelist.com

Dave Bjork is a patient advocate and research evangelist with more than 20 years of progressive experience in nonprofit advocacy, community-building and fundraising leadership roles. He is currently a consultant on the Patient Driven Design team at Medidata Solutions advising on bringing the patient voice to the clinical trial experience. Dave is also host of the Research Evangelist podcast and blog where he interviews people in life sciences that are doing brilliant work in research. Previously Dave served 4 years as Director of Development and Community Relations at FRAXA Research Foundation where he was responsible for building relationships between the Fragile X community and biopharma companies to help advance treatment development in Fragile X syndrome. Before FRAXA Dave spent 4 years as Vice President of Development for National Foundation for Cancer Research where he was responsible for all fundraising and advocacy efforts.

A lung cancer survivor, Bjork has made it his life mission to connect patients, biopharma companies, academic institutions and other key influencers to forge strong partnerships to focus on research. He also advocates for and builds bridges between patient groups and the biopharma industry. Bjork earned a BS in Economics and Finance from the Wharton School at the University of Pennsylvania.

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