New Study by Fox Chase Researchers Determines Critical Roles of BRCA1 Gene in DNA Repair
PHILADELPHIA (April 30, 2020)—In a study published today, researchers at Fox Chase Cancer Center were able to determine that the BRCA1 gene has two distinct and equally important functions in the process of DNA repair, a finding which sheds light on the response and resistance of cancers to certain chemotherapies. The findings have implications for cancer therapy because drugs known as PARP inhibitors successfully treat BRCA1-mutant breast and ovarian cancers