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Christian A. Koch, MD, PhD, FACP, MACE

Christian A. Koch, MD, PhD, FACP, MACE

Clinical Locations

Primary Location

Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111

About

Director, Division of Endocrinology

Professor, Department of Medicine

Endocrinologist

Treatment Focus

Head and Neck Tumors, Pituitary tumors, Adrenal Tumors, Neuroendocrine Tumors

Key Awards

Philadelphia Magazine Top Docs 2020
Endocrinology, Diabetes & Metabolism

Language(s) Other than English

German

Treatment Philosophy

I am excited to be part of the multidisciplinary care at Fox Chase, and to work to improve patients' outcomes. Since endocrinology intersects with all of the other medical disciplines at Fox Chase, I get to interact daily with all my colleagues. I am truly honored to be able to help when cancer treatment affects a patient’s endocrine system. When a patient comes to see me, they can be anxious, depressed, and worried. And my goal is that they leave their appointment with a smile on their face, relieved because they know there’s a solution to it. Fox Chase has a solution to it.

Education and Training

Educational Background

  • DSc, University of Leipzig, “Dr.med.habilitatus”, Leipzig, Germany, 2003
  • Fellowship in Endocrinology, National Institutes of Health, 1998-2001
  • Internship and residency in Internal Medicine,  Ohio State University Hospitals, Columbus, OH, 1994-97
  • Honorary research scholar, Royal Children’s Hospital, Dept. of Endocrinology, Melbourne, Australia, 1996
  • USMLE Step III, USMLE Step II, 1997
  • USMLE Step I (during internship/residency in the U.S.), 1995
  • Residency in neurology, University Hospital Jena, Jena, Germany, 1993
  • PhD, Westfalian-Wilhelms-University, Muenster, Germany, 1993
  • TOEFL (English test) and ECFMG indefinitely # 0-459-402-4, 1993
  • FMGEMS, Part II (clinical sciences), 1991
  • MD,  Friedrich-Alexander University, Erlangen-Nuremberg, Germany, 1991

Certifications

  • Endocrinology
  • Internal Medicine
  • Diplomate, American Board of Clinical Lipidology
    Lipidologist DGFF (Germany)

Memberships

  • Fellow of the American College of Physicians (ACP)
  • Master of the American College of Endocrinologists (AACE)
  • Member of the Southern Society of Clinical Investigation/SSCI
  • American Endocrine Society
  • American Diabetes Association
  • National Lipid Association
  • German Diabetes Association (DDG) and German Diabetologist “DDG”
  • German Endocrine Society
Committee Memberships
  • AACE Pituitary, Gonad, Adrenal and Neuroendocrine Disease State Network, 2018-
  • AACE Adrenal Scientific Committee (Chair: Dr. Karel Pacak), 2016-2018
  • Clinical Guidelines Subcommittee, Endocrine Society (Chair: Dr. Maria Fleseriu), 2015-2018
  • AACE (President: George Gruenberger, MD) Publications Committee, 2015-2018
  • AACE (President: George Gruenberger, MD) Awards Committee, 2015-2018
  • Southern States Chapter of AACE, Board of Directors (President: Dr. Richard Rosenthal), 2015 -2018
  • Council member, Southern Region AFMR (Execut. Dir: E. Chouinard, B. Wagner), 2013-
  • Research Committee, DoM, Univ of Miss Med Center, 2006-2008, 2009-

Honors & Awards

  • Philadelphia Magazine Top Doctors, 2020
  • Master of the American College of Endocrinology = M.A.C.E., 2017
  • US News Top Doctor 2011-2016
  • Castle Connolly America’s Top Doctors 2007-2016
  • The Leading Physicians of the World 2013-2016
  • Best of United States Physicians 2009 (bestofus.com)
  • Patient’s Choice Award 2013-2015
  • Compassionate Doctor Recognition 2013-2015
  • Marquis Who is Who in the World 2009, Biltmore Who’s Who 2009
  • Consultant of the Year Award, Dept of ENT (Chair: S. Stringer, MD), Univ of Mississippi, June 2008
  • O-(utstanding) professor/researcher visa in 2007 and in 2001 (see Google)
  • Winner International Poster Competition, ACP, San Diego, April 2003
  • F.A.C.P. - election in July 2002 (age 37, published academician pathway)
  • F.A.C.E. = Fellow of the American College of Endocrinology 5/2001
  • Young Investigator Award (1st place): AACE, May 2001, Texas
  • Resident outstanding teacher award, The Ohio State University, 1997
Research Profile

Research Interests

  • Neuroendocrinology and Neuroscience
  • Pathogenesis of endocrine tumors incl. pituitary, adrenal, thyroid glands
  • Endocrine Hypertension
  • Endocrine Genetics and hormone resistance / insensitivity syndromes
  • Multiple endocrine neoplasia syndromes
  • Von Hippel Lindau syndrome
  • Adrenal tumors
  • Water metabolism and pituitary disorders (Cushing’s, acromegaly, others)
Publications

Selected Publications

Tharmalingam S, Reddy S, Sharda P, Koch CA. Severe Hypocalcemia and transient hypoparathyroidism after hyperthermic intraperitoneal chemotherapy. Thieme Connect 2020;Aug 7

Oktay AA, Aktürk HK, Paul TK, O'Keefe JH, Ventura HO, Koch CA, Lavie CJ. Diabetes, Cardiomyopathy, and Heart Failure. [Updated 2020 Aug 1]. In: Feingold KR, Anawalt B, Boyce A, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-.

Glasker S, Vergauwen E, Koch CA, Kutikov A, Vortmeyer AO. Von Hippel-Lindau disease: current challenges and future prospects. Onco Targets Ther 2020;June 16:13:5669-5690

Christian A.Koch, RobertoVita, SalvatoreBenvenga, The various faces of hyperthyroidism, Jnl of Clinical & Translational Endocrinology, Vol 20, June 2020, 100229

Gubbi S, Hannah-Shmouni F, Verbalis JG, Koch CA.Hypophysitis: an update on the novel forms, diagnosis and management of disorders of pituitary inflammation. Best Pract Res Clin Endocrinol Metab 2019;Dec 12:101371 doi: 10.1016/j.beem.2019.101371

Fulop T, Zsom L, Hamrahian M, Rodriguez RD, Chabrier-Rosello JO, Koch CA. Therapeutic hypernatremia management during continuous renal replacement therapy with elevated intracranial pressures and respiratory failure. Rev Endocr Metab Disord 2019;20 (1):65-75   

Khan AA, Koch CA, Van Uum SHM, Baillargeon JP, Bollerslev J, Brandi ML, Marcocci C, Rejnmark L, Rizzoli R, Shrayyef MZ, Thakker RV, Yildiz BO, Clarke B. Standards of care for hypoparathyroidism in adults. Eur J Endocrinol 2019,180(3):P1-P22

Koch CA, Krabbe S, Hehmke B. Statins, metformin, proprotein-convertase-subtilisin-kexin type-9 (PCSK9) inhibitors and sex hormones: immunomodulatory properties ? Rev Endocr Metab Disord 2018, Dec (19(4):363-395

Koch CA, Petersenn S. Black swans – neuroendocrine tumors of rare locations. Rev Endocr Metab Disord 2018,Jun;19(2):107-109

Bhanat E, Koch CA, Parmar R, Garla V, Vijayakumar V. Somatostatin receptor expression in non-classical locations - clinical relevance? Rev Endocr Metab Disord. 2018 Jun;19(2):123-132

Dynkevich Y,Rother KI, Whitford I, Qureshi S, Galiveeti S, Szulc AL, Danoff A, Breen TL, Kaviani N, Shanik MH, LeRoith D, Vigneri R, Koch CA, Roth J. Tumors, IGF-2, and hypoglycemia: insights from the clinic, the laboratory and the historical archive. Endocr Rev 2013;34(6):798-826

Fulop T, Farah Musa AR, Koch CA, Hamrahian M, Gharaibeh K, Lengvarsky Z, Pitman KT, Dixit MP. Targeted surgical parathyroidectomy in end-stage renal disease patients and longterm metabolic control: a single-center experience in the current era. Hemodial Int 2018; Jul;22(3):394-404

Kumar E, McCurdy MT, Koch CA, Hamadah A, Fulop T, Gharaibeh KA. Functional impairment of thyroid function in critically ill patients in the intensive care units. Am J Med Sci 2018; 355(3):281-285

Sindoni A, Fama F, Rosano A, Scisca C, Dionigi G, Koch CA, Gioffre-Florio M, Benvenga S. Thyroid nodules coexisting with either cystic or solid breast nodules: a new clue for this association between nodules coming from ultrasonography. Gland Surg 2017;6(6):630-637

Riley DS, Barber MS, Kienle GS, Aronson J, von Schoen-Angerer T, Tugwell P, Helfand M, Kiene H, Werthmann PG, Shamseer L, Moher D, Rison RA, Koch CA, Hanaway P, Sun GH, Altman DG, Sox H, Sudak N, Gagnier JJ. CARE 2013 explanations and elaborations: reporting guidelines for case reports. J Clin Epidemiol 2017; 89:218-235

Fleseriu M, Findling JW, Koch CA, Schlaffer SM, Buchfelder M, Gross C. Changes in plasma ACTH levels and corticotroph tumor size in patients with Cushing's disease during long-term treatment with the glucocorticoid receptor antagonist mifepristone. J Clin Endocrinol Metab 2014;99(10):3718-27     

Melcescu E, Horton WB, Pitman KT, Vijayakumar V, Koch CA. Euthyroid Graves’ orbitopathy and incidental papillary thyroid microcarcinoma. Hormones (Athens) 2013; Apr 12(2):298-304

Agarwal M, Csongradi E, Koch CA, Juncos LA, Echols V, Tapolyai M, Fulop T. Severe symptomatic hypocalcemia after denusomab administration in an end-stage renal disease patient on peritoneal dialysis with controlled secondary hyperparathyroidism. Br J Med & Med Res 2013;3(4):1398-1406

Gharaibeh KA, Craig MJ, Koch CA, Lerant AA, Fulop T, Csongradi E. Desmopressin for hyponatremia overcorrection: an effective adjunct treatment for reversing rapid overcorrection and preventing osmotic demyelination syndrome. World J Clin Cases 2013;August 16; 1(5):155-158... Expand

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