Mark A. Hallman, MD, PhD

Mark A. Hallman, MD, PhD

Clinical Locations

Primary Location

Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111


Assistant Professor, Department of Radiation Oncology

Treatment Focus

My primary role is as a member of the genitourinary cancer program treating adrenal tumors, kidney cancer, penile cancer, prostate cancer, bladder cancer, ureteral cancer, urethral cancer, and testicular cancer.

I have had extensive training in several specialized radiation techniques:

  • Intensity Modulated Radiation Therapy (IMRT)
  • Stereotactic Body Radiation Therapy (SBRT)
  • Prostate Brachytherapy

Research Program

Treatment Philosophy

I earned doctorate degrees in both medicine and pharmacology research at the Medical University of South Carolina enrolled in the Medical Scientist Training Program. After graduation I joined Fox Chase Cancer Center for my medical residency training in the Department of Radiation Oncology. Upon completing residency I was recruited to become a member of the department faculty treating genitourinary cancers and hematologic cancers. As part of that role, I also conduct research and design clinical trials to both improve upon our current treatments and to develop new technologies in the fight against cancer.

While knowledge and expertise are important, I believe that compassion and personalized care are also essential to being an effective physician. I strive to establish trust and understanding with my patients in order to best help them complete complex and intense cancer therapies in order to achieve the best possible outcomes.  This is an exciting time to be at Fox Chase Cancer Center. The faculty and staff at Fox Chase work as a team with the common goal of providing world class cancer treatment. Not only do I have access to state of the art technologies and cutting-edge treatments, but I also have the opportunity to develop new treatments that will improve the way we treat cancer in the future.

Education and Training

Educational Background

  • Resident, Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, 2014
  • Resident, Surgery, Medical University of South Carolina, Charleston, SC, 2010
  • MD/PhD, Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, SC, 2009


  • American Board of Radiology, Diplomate in Radiation Oncology, 2015


  • American Society of Clinical Oncology
  • American Society for Therapeutic Radiology and Oncology
  • Association of Residents in Radiation Oncology
  • Radiological Society of North America
Patient Stories

William O'Brien

Bladder Cancer

William O'Brien

Bladder Cancer

In 2015, Bill O’Brien and his wife, Jackie, celebrated 51 years of marriage. Spending time with friends is very important to them. During a weekly “breakfast club” outing in 2012 – where they meet a group of friends at a local restaurant for breakfast, Bill felt something wasn’t right with him. “I went to the rest room and I started experiencing urinary bleeding," recalls Bill, who realized he needed to see a urologist as soon as possible. Following an exam and testing, the urologist told him that something was detected on his bladder.

Research Profile

Research Program

Research Interests

My research has focused on improving the safety and efficacy of delivering SBRT. I will also focus on developing new ways to deliver radiation treatments to cancers that are otherwise untreatable with conventional therapies. These methods will use exciting new drug and radiation combinations to enhance the effects and targeting of radiation on tumor cells.


Selected Publications

Shaikh T, Handorf EA, Murphy C, Kutikov A, Uzzo RG, Hallman MA, Horwitz EM, Smaldone MC. Contemporary Trends in the Utilization of Radiotherapy in Patients with Renal Cell Carcinoma. Urology, 2015 Sep; in press (PMID: 2638611)

Radiation therapy to the primary tumor in locally advanced prostate cancer is not "closing the barn door after the horse has bolted" Zaorsky N, Hallman MA, Smaldone MC.
Annals of Translational Medicine, 2015 Oct; 3(18):274.

Effects of active and inactive phospholipase D2 on signal transduction, adhesion, migration, invasion, and metastasis in EL4 lymphoma cells. Knoepp SM, Chahal MS, Xie Y, Zhang Z, Brauner DJ, Hallman MA, Robinson SA, Han S, Imai M, Tomlinson S, Meier KE. Mol Pharmacol, 2008 Sep;74(3):574-84.

Regulation of dedifferentiation and redifferentiation in renal proximal tubular cells by the epidermal growth factor receptor. Hallman MA, Zhuang S, Schnellmann RG. J Pharmacol Exp Ther, 2008 May;325(2):520-8.

RasGRP1 confers the phorbol ester-sensitive phenotype to EL4 lymphoma cells. Han S, Knoepp SM, Hallman MA, Meier KE, Mol Pharmacol. 2007 Jan;71(1):314-22.

Effect of antioxidants on para-aminophenol-induced toxicity in LLC-PK1 cells. Hallman MA, Tcaho R, Tarloff JB. Toxicology, 2000 Dec;156(1):37-45.



Our Patient Satisfaction Rating is an average of all responses to care provider related questions from our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more.


5.0 / 5.0


  • 4.9
  • 5.0
  • 5.0
  • 5.0
  • 5.0


  • 5.0
    June 10, 2022
    Dr. Hallman & staff could not be nicer. Clerks at check in could be nicer.
  • 5.0
    May 31, 2022
    Both Dr. Hallman & his nurse were courteous, professional, & sensitive to my needs & concerns. Excellent.
  • 5.0
    May 29, 2022
    Doctor Hallman and his team are the best.
  • 5.0
    May 01, 2022
    Very good experience, they made me feel comfortable thru out my complete visit.
  • 5.0
    April 29, 2022
    From the receptionist to the nurses to Dr. Hallman are very efficient helpful, and very effective. Best choice I ever made in a doctor and place of business.
  • 5.0
    April 22, 2022
    Always very professional and a pleasure to see
  • 5.0
    March 16, 2022
    Excellent treatment & care.
  • 5.0
    March 03, 2022
    It is always a good experience to see Dr. Hallman and to come to FCCC for follow up appointments
  • 5.0
    January 10, 2022
    Dr. Hallman & the rest of the staff are excellent to me.
  • 5.0
    January 07, 2022
    Dr. Hallman did an excellent job as did his nurse.
  • 5.0
    October 25, 2021
    Very satisfying visit.
  • 5.0
    September 24, 2021
    I alway have an excellent experience when seeing Dr Hallman and his staff.
  • 5.0
    September 20, 2021
    Dr. Hallman is a wonderful and caring physician. I like and respect him very much.
  • 5.0
    September 02, 2021
    Always a pleasure seeing them friendly and attentive
  • 5.0
    August 19, 2021
    I had a very good experience with the provider & his nurse and the clerical staff.
  • 5.0
    August 10, 2021
    Doctor Hellman is a excellent doctor.
  • 5.0
    August 05, 2021
    After all visits I felt that the doctors & staff were concerned about my well being.
  • 5.0
    July 27, 2021
    Great experience.
  • 5.0
    July 24, 2021
    The nurse and doctor were very professional and friendly during my visit; I had a lot of confidence in both of them. I was there for a second opinion pertaining to prostate cancer and they were most helpful in treating me and answering my concerns and questions. Other staff members such as receptionists were also very respectful and efficient.
  • 5.0
    June 02, 2021
    [...] the doctor's nurse practitioner was super great - funny, relaxing to speak with, knowledgeable - this was a pleasant experience under the circumstance. Of course Dr. Hallman is the best of all the doctor there. 100% of our care is how we are treated physically & also mentally. Your staff covered both those area well. I've told all who are going through any type of cancer, go to Fox Chase! Thank y'all very much.

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