Mark A. Hallman, MD, PhD

Mark A. Hallman, MD, PhD

Clinical Locations

Primary Location

Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111


Assistant Professor, Department of Radiation Oncology

Treatment Focus

My primary role is as a member of the genitourinary cancer program treating adrenal tumors, kidney cancer, penile cancer, prostate cancer, bladder cancer, ureteral cancer, urethral cancer, and testicular cancer.

I have had extensive training in several specialized radiation techniques:

  • Intensity Modulated Radiation Therapy (IMRT)
  • Stereotactic Body Radiation Therapy (SBRT)
  • Prostate Brachytherapy

Research Program

Treatment Philosophy

I earned doctorate degrees in both medicine and pharmacology research at the Medical University of South Carolina enrolled in the Medical Scientist Training Program. After graduation I joined Fox Chase Cancer Center for my medical residency training in the Department of Radiation Oncology. Upon completing residency I was recruited to become a member of the department faculty treating genitourinary cancers and hematologic cancers. As part of that role, I also conduct research and design clinical trials to both improve upon our current treatments and to develop new technologies in the fight against cancer.

While knowledge and expertise are important, I believe that compassion and personalized care are also essential to being an effective physician. I strive to establish trust and understanding with my patients in order to best help them complete complex and intense cancer therapies in order to achieve the best possible outcomes.  This is an exciting time to be at Fox Chase Cancer Center. The faculty and staff at Fox Chase work as a team with the common goal of providing world class cancer treatment. Not only do I have access to state of the art technologies and cutting-edge treatments, but I also have the opportunity to develop new treatments that will improve the way we treat cancer in the future.

Education and Training

Educational Background

  • Resident, Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, 2014
  • Resident, Surgery, Medical University of South Carolina, Charleston, SC, 2010
  • MD/PhD, Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, SC, 2009


  • American Board of Radiology, Diplomate in Radiation Oncology, 2015


  • American Society of Clinical Oncology
  • American Society for Therapeutic Radiology and Oncology
  • Association of Residents in Radiation Oncology
  • Radiological Society of North America
Patient Stories

William O'Brien

Bladder Cancer

William O'Brien

Bladder Cancer

In 2015, Bill O’Brien and his wife, Jackie, celebrated 51 years of marriage. Spending time with friends is very important to them. During a weekly “breakfast club” outing in 2012 – where they meet a group of friends at a local restaurant for breakfast, Bill felt something wasn’t right with him. “I went to the rest room and I started experiencing urinary bleeding," recalls Bill, who realized he needed to see a urologist as soon as possible. Following an exam and testing, the urologist told him that something was detected on his bladder.

Research Profile

Research Program

Research Interests

My research has focused on improving the safety and efficacy of delivering SBRT. I will also focus on developing new ways to deliver radiation treatments to cancers that are otherwise untreatable with conventional therapies. These methods will use exciting new drug and radiation combinations to enhance the effects and targeting of radiation on tumor cells.


Selected Publications

Shaikh T, Handorf EA, Murphy C, Kutikov A, Uzzo RG, Hallman MA, Horwitz EM, Smaldone MC. Contemporary Trends in the Utilization of Radiotherapy in Patients with Renal Cell Carcinoma. Urology, 2015 Sep; in press (PMID: 2638611)

Radiation therapy to the primary tumor in locally advanced prostate cancer is not "closing the barn door after the horse has bolted" Zaorsky N, Hallman MA, Smaldone MC.
Annals of Translational Medicine, 2015 Oct; 3(18):274.

Effects of active and inactive phospholipase D2 on signal transduction, adhesion, migration, invasion, and metastasis in EL4 lymphoma cells. Knoepp SM, Chahal MS, Xie Y, Zhang Z, Brauner DJ, Hallman MA, Robinson SA, Han S, Imai M, Tomlinson S, Meier KE. Mol Pharmacol, 2008 Sep;74(3):574-84.

Regulation of dedifferentiation and redifferentiation in renal proximal tubular cells by the epidermal growth factor receptor. Hallman MA, Zhuang S, Schnellmann RG. J Pharmacol Exp Ther, 2008 May;325(2):520-8.

RasGRP1 confers the phorbol ester-sensitive phenotype to EL4 lymphoma cells. Han S, Knoepp SM, Hallman MA, Meier KE, Mol Pharmacol. 2007 Jan;71(1):314-22.

Effect of antioxidants on para-aminophenol-induced toxicity in LLC-PK1 cells. Hallman MA, Tcaho R, Tarloff JB. Toxicology, 2000 Dec;156(1):37-45.



Our Patient Satisfaction Rating is an average of all responses to care provider related questions from our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more.


4.9 / 5.0


  • 4.8
  • 4.9
  • 5.0
  • 5.0
  • 5.0


  • 5.0
    July 27, 2021
    Great experience.
  • 5.0
    July 24, 2021
    The nurse and doctor were very professional and friendly during my visit; I had a lot of confidence in both of them. I was there for a second opinion pertaining to prostate cancer and they were most helpful in treating me and answering my concerns and questions. Other staff members such as receptionists were also very respectful and efficient.
  • 5.0
    June 02, 2021
    [...] the doctor's nurse practitioner was super great - funny, relaxing to speak with, knowledgeable - this was a pleasant experience under the circumstance. Of course Dr. Hallman is the best of all the doctor there. 100% of our care is how we are treated physically & also mentally. Your staff covered both those area well. I've told all who are going through any type of cancer, go to Fox Chase! Thank y'all very much.
  • No Star Ratings Available May 29, 2021
    very good
  • No Star Ratings Available April 07, 2021
    explained treatment options and outcomes and risks are clearly. answered all my questions
  • 5.0
    April 04, 2021
    always a good
  • 5.0
    March 22, 2021
    Exceptional care.
  • 5.0
    March 17, 2021
    Dr. Hallman answered all my questions & provided me with options I did not know about. Great experience.
  • No Star Ratings Available February 26, 2021
    Dr. Hallman is fabulous, professional and kind.
  • 5.0
    February 23, 2021
    Nothing but good things.
  • No Star Ratings Available February 13, 2021
    He listens and answers questions that are easy to understand.
  • No Star Ratings Available February 08, 2021
    Doctor spent plenty of time with me to make sure I understood all my options, & the reasons why certain options were not available to me
  • 5.0
    January 25, 2021
    My experience overall was very good, and received very professional care.
  • 5.0
    January 07, 2021
    Dr. Hallman was very professional and spent time with me explaining therapy, a good dr.
  • No Star Ratings Available November 26, 2020
    Dr Hollman was exceptional in all categories [...]. He clearly and succinctly presented all options and answered all of my questions. I was very impressed with his intelligence and and caring demeanor. I would highly recommend him to anyone.
  • 5.0
    October 26, 2020
    Dr. Hallman and his staff were excellent!
  • 5.0
    October 20, 2020
    I am very well satisfied by the treatment/care provided to me by Dr. Hallman and his staff.
  • 5.0
    October 16, 2020
    Excellent & thorough provider. NP was also excellent friendly informative & empathetic. [...]
  • 5.0
    October 06, 2020
  • 5.0
    August 28, 2020
    Dr. Hallman and his nurse [...] are great.

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