AKT Symposium

Date & Time


Philadelphia Marriott Downtown
1201 Market Street
Philadelphia, PA 19107

Registration Information

To register, please visit: http://foxchase.kintera.org/AKTsymposium or call 215-728-3603. 

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October 2016 marks the 25th anniversary of a landmark study that originated in a laboratory at Fox Chase Cancer Center. The study, by Fox Chase researchers Philip Tsichlis, Joseph R. Testa and Alfonso Bellacosa, and by Kaiser Permanente oncologist Stephen Staal, revealed that the retroviral oncogene AKT codes for a kinase, an enzyme that phosphorylates other cellular proteins, and also contains a regulatory region similar to molecules that function in protein-protein interactions involved in critical cell signaling pathways.  This study is considered the starting point for a plethora of research that significantly impacted the field of cancer throughout the world (more than 50,000 research articles have been published that include AKT in the title or abstract).  AKT kinases are often activated in human cancer and increase survival and tumorigenicity of cancer cells.  Alterations of AKT sequence and/or activity are also reported in non-cancerous disease, such as developmental disorders, autistic spectrum disorders, cardiovascular disease and diabetes.  This one-day Symposium will feature state-of-the-art presentations by the original authors and leaders in the AKT field, and will showcase the long-term impact of basic science, including improvement of cancer therapy through precision medicine.


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Check-in: Check-in begins at 8:00 a.m. and a continental breakfast will be provided. 


Parking: Valet and self-parking are available in the garage adjacent to the hotel for a fee. Directions to the hotel can be found using the following link: http://www.marriott.com/hotelwebsites/us/p/phldt/pdf/PHLDT_Directions_V4.pdf. [PDF]


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