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Organic Synthesis Facility
|Director:||Roland L. Dunbrack, Jr, PhD|
|Manager:||Cynthia Myers, MS
|Contact Cynthia Myers for pricing and scheduling.|
The primary purpose of the Organic Synthesis Facility is to produce the highest quality synthetic molecules for investigators in order to enhance scientific research conducted at the Center. The facility focuses on the development of unique molecules or novel synthetic methods whenever possible. Members of the facility also provide important services, including purification of reagents, analyses of molecules and consultation to provide needed chemical information. Preparative HPLC (high performance liquid chromatography), Combiflash Rf+ chromatography system, distillation, recrystallization and extraction are the most commonly used methods for purification of reagents, solvents and synthesized compounds.
Analytical services performed by facility staff include mass spectrometry (LC-MS), nuclear magnetic resonance (NMR) spectroscopy (1H, 13C, 31P), thin-layer chromatography (TLC) and HPLC. Consultation is provided to investigators who are searching for information about chemical compounds, chemical literature, synthetic methods, analytical methods, purification methods, equipment or glassware. In addition, the facility offers a computer-based catalog of a large stock of chemical reagents (comprising more than 1,500 different chemicals) available for use by the research community.