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Fox Chase Cancer Center News

July 26, 2019

Powerful Chromosome Analysis Allows for More Accurate Subtyping of Renal Cell Carcinomas

PHILADELPHIA (July 26, 2019) – Shuanzeng Wei, MD, PhD, and colleagues used SNP-based chromosome microarrays to analyze 14 tumor samples taken from patients with low-grade renal cell carcinoma with both clear cell and papillary features. This technology allowed them to perform genome-wide screening and identify genetic copy number variations at a much higher resolution than that of standard or high-resolution chromosome analysis.  

Dr.Andrews and his team attempted to map acetylation of H3 in Saccharomyces cerevisiae, more commonly known as baker’s yeast. “By looking at a simple system without the complex levels of regulatory functions seen in humans, we can get a better understanding of what Asf1 is doing before adding additional complexity,” Andrews said.
July 25, 2019

Histone Chaperone Asf1 Mediates Crosstalk Between H3K14 and H3K56 Acetylation

PHILADELPHIA (July 25, 2019) – Researchers at Fox Chase Cancer Center have found that Asf1 recognizes lysine 14 of histone H3 (H3K14) and facilitates the acetylation of H3K56 by the lysine acetyltransferase (KAT) Rtt019-Vps75.

In 2016, Dr. Anari joined Fox Chase Cancer Center/Temple University for a three-year fellowship in hematology/oncology. She begins full-time on August 5th.
July 23, 2019

Fern Anari Joins the Division of Genitourinary Medical Oncology at Fox Chase Cancer Center

PHILADELPHIA (July 23, 2019) – Fox Chase Cancer Center is pleased to announce the hiring of Fern Anari, MD, who will join the faculty as assistant professor in the Division of Genitourinary Medical Oncology within the Department of Hematology/Oncology.

Jennifer Barsky Reese, PhD, assistant professor in the Cancer Prevention and Control Program at Fox Chase, developed iSHARE in order to address communication barriers and educate clinicians on ways to facilitate sexual health dialogue with patients.
July 22, 2019

Novel Intervention Promotes Sexual Health Dialogue Between Breast Cancer Patients and Physicians

PHILADELPHIA (July 22, 2019) – Researchers at Fox Chase Cancer Center have developed iSHARE, or Sexual Health and Augmenting Relationships through Education, a novel communication intervention to promote discussions about sexual health with breast cancer patients.

July 22, 2019

Fox Chase Cancer Center Welcomes Iberia Romina Sosa

PHILADELPHIA (July 22, 2019) – Fox Chase Cancer Center is pleased to announce the hiring of Iberia Romina Sosa, MD, PhD, to the department of Hematology/Oncology.

July 16, 2019

Fox Chase Celebrates Cancer Survivors at the Phillies

Fox Chase Cancer Center community celebrated cancer survivorship on Saturday, July 13 as the Philadelphia Phillies played the Washington Nationals.

The critical role of inflammation in cancer may be getting a bit lost, according to Sergei Grivennikov, PhD, assistant professor in the Cancer Prevention & Control Program at Fox Chase Cancer Center.
July 15, 2019

Increased Understanding of Inflammation’s Role in Cancer Should Shape Future Basic Discoveries, Clinical Trials and Drug Development

PHILADELPHIA (July 16, 2019) – Inflammation plays an instrumental role in tumor development, affecting the tumor microenvironment, immune responses, and tumor growth and spread. This critical role in cancer may be getting a bit lost.

According to Reddy, pancreatic tumors will often compress the bile ducts, obstructing bile from flowing freely. Undergoing a biliary stent procedure can alleviate the compression, allowing bile to properly drain.
July 5, 2019

Biliary Microbiome Altered After Neoadjuvant Therapy for Pancreatic Cancer

PHILADELPHIA (July 5, 2019) — The biliary microbiome was altered in patients who received neoadjuvant therapy prior to undergoing surgery for pancreatic cancer, according to new research from Fox Chase Cancer Center.

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