Solved Protein Structure Holds Key To Much-Needed Therapies For Metabolic Disorder
PHILADELPHIA (February 16, 2016) – Phenylketonuria, also known as PKU, is the most common inherited disease affecting amino acid metabolism. In a study published February 15th in Proceedings of the National Academy of Sciences, Fox Chase Cancer Center – Temple Health researchers made tremendous strides toward that goal by shedding new light on the structure of phenylalanine hydroxylase (PAH)—the enzyme that is defective in PKU patients.