Preclinical Study Demonstrates Potential Efficacy of Vaccine for Preventing Colon Cancer in High-Risk Populations
PHILADELPHIA (April 21, 2021)—Researchers at Fox Chase Cancer have published a study investigating the safety and efficacy of a vaccine, given alone and in combination with a PD-1 checkpoint inhibitor, that may prevent colon cancer in certain populations. In a preclinical in vivo model, when administered to mice predisposed to develop colon cancer, the vaccine primed their immune systems to recognize and fight cancer cells and prevent tumors from forming.