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Chang-Ming Charlie Ma, PhD, FASTRO

Charlie Chang-Ming Ma, MD

Clinical Locations

Primary Location

Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111

About

Professor

Vice Chairman, Department of Radiation Oncology

Director, Radiation Physics

Research Program

Lab Overview

The radiation physics and cancer biology laboratory uses cancer animal models, in particular prostate, head and neck, breast, lung, pancreatic, ovarian and other diseases for understanding pathogenesis and developing novel therapeutic approaches. The staff perform cancer treatment studies combining radiation therapy, radio-dynamic therapy, gene therapy, chemotherapy, nanotherapy, and MR-guided high intensity focused ultrasound therapy.

 
High-intensity focused ultrasound (HIFU)
Electron-specific multileaf collimator
Electron-specific multileaf collimator
Laser proton accelerator
Experimental acceleration for proton acceleration
Coulomb mirror effect

 

Education and Training

Educational Background

  • Postdoctoral Fellow, Medical Physics, Royal Marsden Hospital, Institute of Cancer Research, Sutton, U.K., 1993
  • PhD, Royal Marsden Hospital/Institute of Cancer Research/London University, Sutton, U.K., 1991
  • MS, University of Shanghai for Science & Technology, Shanghai, China, 1986
  • BS, Zhejiang University, Hangzhou, China, 1982

Certifications

  • Therapeutic Radiologic Physics, American Board of Radiology, 2004

Memberships

  • Institute of Physics
  • American Association of Physicists in Medicine (AAPM)
  • American College of Medical Physics (ACMP)
  • American Society for Therapeutic Radiology and Oncology (ASTRO)
  • European Society for Therapeutic Radiology and Oncology (ESTRO)
  • Canadian Organization of Medical Physicists (COMP)
  • Cyberknife Society (CS)
  • Society of Directors of Academic Medical Physicists Programs (SDAMPP)
  • AAPM San Francisco Bay Area Chapter (SFBAC)
  • AAPM Delaware Valley Chapter (DVC)
  • North American Chinese Medical Physicists Association (NACMPA)

Honors & Awards

  • Hall of Fame, NACMPA, 2015
  • Fellow, ASTRO, 2014
  • Fellow, ACMP, 2010
  • Fellow, AAPM, 2005
  • Fellow, Institute of Physics (IOP), 2004
  • "Who’s Who in American Medicine and Healthcare," 2005 -
  • "Who’s Who in American Education," 2005 -
  • "Who’s Who in the World," 2005 -
  • "Who’s Who in America," 2004 -
Research Profile

Research Program

Lab Description

The Radiation Physics section consists of radiation physicists, research scientists and fellows, dosimetrists, simulation and therapy technologists and other technical and supporting staff, who are responsible for accurate planning and delivery of radiation dose for radiation therapy. The mission is to provide the best possible technical support for radiation therapy and to advance the efficacy of cancer treatment through the integration of new technical innovations with clinical and basic research. The radiation cancer biology laboratory uses cancer animal models, in particular prostate, head and neck, breast, lung, pancreatic, ovarian and other diseases for understanding pathogenesis and developing novel therapeutic approaches. The staff perform cancer treatment studies combining radiation therapy, radio-dynamic therapy, gene therapy, chemotherapy, nanotherapy, and MR-guided high intensity focused ultrasound therapy.

Our current research projects include image-guided radiotherapy (IGRT), advanced treatment delivery techniques such as intensity modulated radiation therapy (IMRT) and volumetric modulated radiotherapy (VMAT), stereotactic radiosurgery and stereotactic body radiotherapy (SRS/SBRT), pulsed low-dose-rate radiotherapy (PLDR), radiodynamic therapy (RDT), MRI guided HIFU therapy, laser accelerated proton and light ion beams, target localization, organ motion compensation, MRI/PET based functional imaging and treatment assessment, Monte Carlo dose calculation, and analyses of biological effects of radiation.

Lab Staff

Robert Price, PhD, DABR, FASTRO

Professor, Clinical Chief Physicist

Room: P0071
215-728-2819

Lili Chen, PhD

Professor, Clinical Physicist

Room: P0079
215-728-3003

Lu Wang, PhD

Professor, Clinical Physicist

Room: FCCC Buckingham
215-794-2700

Lihui (Max) Jin, PhD

Assistant Professor, Clinical Physicist

Room: P0074
215-214-3852

Teh Lin, PhD

Associate Professor, Clinical Physicist

Room: P0076
215-214-3756

Iavor Veltchev, PhD

Associate Professor, Clinical Physicist

Room: P0073
215-728-2854

Ahmed Eldib, PhD

Assistant Professor, Clinical Physicist

Room: P0101
215-728-3770

Xiaoming (Shawn) Chen, PhD

Assistant Professor, Clinical Physicist

Room: P0081
215-214-5665

Jie Liu, PhD

Assistant Professor

Room: P0075
215-214-3931

Troy Dos Santos, PhD

Medical Physics Resident

Room: P0103
215-728-3071

Huan Liu, PhD

Medical Physics Resident

Room: P0103
215-214-1711

Dae-Myoung Yang, PhD

Medical Physics Resident

Room: P0103
215-214-1426

Dusica Cvetkovic, MD

Research Associate

Room: W230
215-728-3661

Lorraine Medoro

Staff Assistant

Room: P0070
215-728-3043

Additional Staff

George Cherian - Dosimetrist
Kevin Crawford - Dosimetrist
Patrice Boyle - Dosimetrist
Robert Gleason - Dosimetrist
Zheng Dong - Dosimetrist
Gage Price -Dosimetrist 

Mary Ann Konopka - Chief Therapist

Sue Gabriel - Radiation Therapy Scheduler
Thomas Sprankle - Systems Implementation Specialist
Matthew Young - Systems Analyst
Jon Christman - Radiation Oncology Engineer
Dave Liounis - Radiation Oncology Engineer
Chris Davis -  Transport/Mold Room Technician

Jarrett Brown - Staff Therapist
Ronald Brown - Staff Therapist
Sandee Clibanoff  - Staff Therapist
Kristen Cosgrove - Staff Therapist
Kristy Esterly - Staff Therapist
Barbara Farley-McDonnell - Staff Therapist
Alyssa Green​ - Staff Therapist
Michael Gutierrez - Staff Therapist
Donna Hazlett - Staff Therapist
Tracey Murphy - Staff Therapist
Michael Murray - Staff Therapist
Robert Novak - Staff Therapist
Amanda Przywitowski - Staff Therapist
Dominic Sabato - Staff Therapist
Noelle Schillinger - Staff Therapist
Barbara Sims - Staff Therapist
Linda Smith - Staff Therapist 
Stephanie Taccard - Staff Therapist
Donna Videtto - Staff Therapist

Deborah Weitzner - Manager, Rad Onc Coding/Compliance (Therapist)


Donna Dodaro - Pool Therapist
Megan Gleason - Pool Therapist
Sarah Hill - Pool Therapist
Kimberly Kelly- Pool Therapist
Megan Lutey​ - Pool Therapist
Ruth Slotwinski - Pool Therapist
 

Karen Cummins - Simulation Therapist
Maureen Ferri - Simulation Therapist
Susan Gallelli, RTT - Simulation Therapist
Kelly Hopkins - Simulation Therapist
Theresa Richardson - Simulation Therapist

Publications

Selected Publications

Eldib A, Fareed M, Weiss S, Hayes S, Nguyen B, Mora G, Li JS, Chibani O, Addelgawad M and Ma CM. Dosimetric evaluation of a rotating gamma-ray system for stereotactic body radiation therapy, Journal of Radiation Oncology (2020) https://doi.org/10.1007/s13566-020-00437-9

Panetta J, Cvetkovic D, Chen X, Chen L, Ma CM. Radiodynamic therapy using 15-MV radiation combined with 5-aminolevulinic acid and carbamide peroxide for prostate cancer in vivo. Phys Med Biol, 2020 https://doi.org/10.1088/1361-6560/ab9776

Price RA, Jin LH, Meyer J, Chen L, Lin T, Eldib A, Chen X, Liu J, Veltchev I, Wang L and Ma CM. Practical Clinical Implementation of the Special Physics Consultation Process in the Re-irradiation Environment, Advances in Radiation Oncology (2020) https://doi.org/10.1016/j.adro.2020.09.027

Xu Q, Tong X, Lin M, Chen X, Eldib A, Lin T, Chen L and Ma CM, Feasibility of Real-Time Target Localization Using EPID for Prostate IMRT/VMAT, Phys Med. (2020) 76:142-9

Ma CM, Chetty IJ, Deng J, Faddegon B, Jiang SB, Li JS, Seuntjens J, Siebers JV, Traneus E, Beam modeling and beam model commissioning for Monte Carlo dose calculation-based radiation therapy treatment planning: Report of AAPM Task Group 157. Med Phys. 2020. 47:e1-e18; first published PMID: 2019. 31679157. doi: 10.1002/mp.13898

Paly J, Deng M, Lee CT, Hayes SB, Galloway TJ, Hallman MA, Weiss SE, Horwitz EM, Price RA, Ma CM, Meyer JE. Pelvic Reirradiation Utilizing Pulsed Low-dose Rate Radiation Therapy, American Journal of Clinical Oncology, 2020, doi: 10.1097/COC.0000000000000741

Lin T and Ma CM. Positioning Errors of Metal Localization Devices with Motion Artifacts on kV and MV Cone Beam CT, British Journal of Radiology/open, 2019 https://doi.org/10.1259/bjro.20190013

Veltchev I, Price R, Chen X, Howell K, Meyer J and Ma CM. Application of a directional palladium-103 brachytherapy device on a curved surface, Med Phys (2019) 46: 1905-15

Ma CM. Physics and Dosimetric Principles of SRS and SBRT, Mathews J Cancer Sci. (2019) 4(2): 22; DOI: DOI: https://doi.org/10.30654/MJCS.10022

Kry SF, Feygelman V, Balter P, Knöös T, Ma CM, Snyder M, Tonner B, Vassiliev ON, AAPM Task Group 329: Reference dose specification for dose calculations: dose-to-water or dose-to-muscle? Med Phys 2019 PMID: 31883390. doi: 10.1002/mp.13995

 

Additional Publications

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