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Robert G. Uzzo, MD, MBA, FACS

Robert Uzzo, MD, FACS

Clinical Locations

Primary Location

Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111

Secondary Location

Huntingdon Pike
8 Huntingdon Pike
Rockledge, PA

About

Interim CEO, Fox Chase Cancer Center

Chairman, Department of Surgery

G. Willing "Wing" Pepper Chair in Cancer Research

Professor, Department of Surgery

Professor of Surgery, Temple University Health System

Adjunct Professor of Bioengineering, Temple University College of Engineering

Treatment Focus

  • Robotic and laparoscopic urologic oncology
  • Organ preservation (kidney, bladder, testicular and adrenal)
  • Non-surgical management of low risk urinary tumors
  • Complex urological reconstruction

Research Program

Key Awards

Philadelphia Magazine Top Docs 2021
Urology

Treatment Philosophy

I believe in treating patients as I would my own family. I strive to communicate effectively with patients and family members at all levels. Through extensive discussions with my patients, I develop treatment plans that are both effective and acknowledge that quality of life issues are exceptionally important. I emphasize individually tailored treatments to help patients achieve success and limit treatment-related side effects which can affect quality of life.

I am sensitive to the particular issues regarding surgical treatment of genitourinary cancer, especially the physical and emotional effects on patients and their family. By fostering a doctor-patient relationship based on mutual respect and open dialogue, I encourage patients to become empowered managers of their care... Expand

 

Follow on Twitter: @FCUroOnc

View Dr. Uzzo's PracticeUpdate contributions

Chairman, Department of Surgery

Nationally known as a leader in the field of urologic oncology, Dr. Uzzo has made important clinical, scientific and educational contributions to the Department of Surgery.

A fellow of the American College of Surgeons, Uzzo has consistently ranked among Castle Connolly’s and Philadelphia Magazine's "Top Docs" in urology. He is a national principal investigator for a clinical trial by the Eastern Cooperative Oncology Group to evaluate new, targeted therapies for kidney cancers and immunotherapy.  He is the author of more than 350 chapters, articles, books and abstracts on urologic tumors and has presented hundreds of regional, national and international lectures.

In addition to his extensive clinical practice, he oversees research laboratory initiatives studying molecular mechanisms of genitourinary cancers. In 2003, he was promoted from Associate Professor to Professor with tenure in Fox Chase's division of medical science... Expand

Education and Training

Educational Background

  • Fellow, Urologic Oncology, Cleveland Clinic Foundation
  • Fellow, Renal Transplantation and Renovascular Surgery, Cleveland Clinic Foundation
  • Chief Resident, Urology, New York Hospital-Cornell University Medical Center, New York, NY
  • Senior Resident, Urology, Memorial Sloan-Kettering Cancer Center, New York, NY
  • MD, Cornell Medical College, New York, NY, 1991
  • BS/BA, Union College, Schenectady, NY, 1989, Valedictorian

Certifications

  • Diplomate, American Board of Urology

Memberships

  • The American Urological Association
  • Member, American Association of Genitourinary Surgeons, AAGUS
  • Society of Urologic Oncology, Board of Directors
  • Society of Urologic Oncology, Clinical Trials Consortium, President 
  • Society of Urologic Oncology, Clinical Trials Consortium, Renal Program Chairman  
  • Board of Directors, SUO Clinical Trials Consortia, member-at-large  
  • Fox Chase Cancer Center Society of Scholars  
  • Kidney Cancer Association Medical Advisory Board  
  • Fellow American College of Surgeons (F.A.C.S.)  
  • Society of Urologic Oncology  
  • Pennsylvania Medical Society
  • Philadelphia County Medical Society  
  • The MidAtlantic Section of the American Urological Association
  • Eastern Cooperative Oncology Group  
  • Radiation Therapy Oncology Group
  • American College of Surgeons Oncology Group - Vice Chairman, GU Organ Committee   2002-2006 
  • American Society of Transplant Surgeons 
  • Urologic Society of Transplant and Vascular Surgeons
  • Society for Basic Urologic Research  
  • American Association for Cancer Research

Honors & Awards

  • Philadelphia Magazine Top Doctors, 2002-20
  • Best Doctors in America®, 2013-16, 2019-2020, Urology
  • America’s Top Doctors®, 2008-17
  • AUA Residents National Committee Teaching Award
  • Consumer’s Research Council of America –America’s Top Physicians 
Patient Stories

Tina Pidgeon

Kidney Cancer

Tina Pidgeon

Kidney Cancer

Eleven years ago, I went in for a routine ultrasound to evaluate my pregnancy. I had no idea that the test would completely change my life and lead to a diagnosis of kidney cancer.

David Hiltgen

Kidney Cancer

David Hiltgen

Kidney Cancer

My kidney cancer was discovered at the worst time: right at the start of the COVID-19 pandemic.

Luciano Orsini

Kidney Cancer

Luciano Orsini

Kidney Cancer

I’m 58 years old and live in Sicklerville, New Jersey. In normal times, summer is my favorite time of year. I’d have been looking forward to it this year, if COVID-19 hadn’t happened and forced me to delay my surgery for kidney cancer.

Felix (Phil) Sanchez

Bladder Cancer

Felix (Phil) Sanchez

Bladder Cancer

I follow up with people and act as a mentor. I let them know they are able to contact me at any time, and I can offer them peace of mind from someone who has been where they are headed.

Charlie Smithgall

Kidney Cancer

Charlie Smithgall

Kidney Cancer

"Although cancer is not the news I was expecting to hear, I’m able to see the silver lining in how things worked out the way they did. "

Pages

Research Profile

Research Program

Research Interests

  • Clinical and translational questions involving renal cell carcinoma including decision making models in the management of renal cancers and processes/quality of care in urologic malignancies
  • Analyses of outcomes involving excision, ablation, and active surveillance for localized kidney cancer and techniques/outcomes of surgery in locally advanced and metastatic RCC
  • Actively develop and accrue to multiple industry sponsored national and international urological oncology trials as well as investigator initiated trials.
  • Translational interests include biomarker development in kidney cancer and the role of zinc dyshomeostasis in prostate cancer
Publications

Selected Publications

Chapters and Publications from over 400:

Campbell S.C., Novick A.C., Belldegrun A., Blute M.L., Chow G.K., Derweesh I.H., Faraday M.M., Kaouk J.H., Leveillee R.J., Matin S.F., Russo P., Uzzo R.G., Guideline for Management of the Clinical T1 Renal Mass, 2009, Journal of Urology, 182, 4 SUPPL., 1271, 1279 PubMed

Goel N, Manstein SM, Ward WH, DeMora L, Smaldone MC, Farma JM, Uzzo RG, Esnaola NF. Does the Surgical Apgar Score predict serious complications after elective major cancer surgery? Journal of Surgical Research, 231:242-7, 2018. 

Uzzo R.G., Novick A.C., Nephron sparing surgery for renal tumors: Indications, techniques and outcomes, 2001, Journal of Urology, 166, 1, 6, 18 PubMed

Kutikov A, Uzzo RG. The RENAL Nephrometry Score: A comprehensive standardized system for quantitating renal tumor size, location and depth. J Urol, 182(3):844-53, 2009. (cited 401 times) PubMed

Chawla S.N., Crispen P.L., Hanlon A.L., Greenberg R.E., Chen D.Y.T., Uzzo R.G., The natural history of observed enhancing renal masses: Meta-analysis and review of the world literature, 2006, Journal of Urology, 175, 2, 425, 431 PubMed

Kunkle D.A., Egleston B.L., Uzzo R.G., Excise, Ablate or Observe: The Small Renal Mass Dilemma-A Meta-Analysis and Review, 2008, Journal of Urology, 179, 4, 1227, 1234 PubMed

Kunkle D.A., Uzzo R.G., Cryoablation or radiofrequency ablation of the small renal mass: A meta-analysis, 2008, Cancer, 113, 10, 2671, 2680 PubMed

Uzzo R.G., Wei J.T., Waldbaum R.S., Perlmutter A.P., Byrne J.C., Vaughan Jr. D., The influence of prostate size on cancer detection, 1995, Urology, 46, 6, 831, 836 PubMed

Pollack A., Hanlon A.L., Horwitz E.M., Feigenberg S.J., Konski A.A., Movsas B., Greenberg R.E., Uzzo R.G., Ma C.-M.C., McNeeley S.W., Buyyounouski M.K., Price Jr. R.A., Dosimetry and preliminary acute toxicity in the first 100 men treated for prostate cancer on a randomized hypofractionation dose escalation trial, 2006, International Journal of Radiation Oncology Biology Physics, 64, 2, 518, 526 PubMed

Qiao J., Uzzo R., Obara-Ishihara T., Degenstein L., Fuchs E., Herzlinger D., FGF-7 modulates ureteric bud growth and nephron number in the developing kidney, 1999, Development, 126, 3, 547, 554

Lane B.R., Russo P., Uzzo R.G., Hernandez A.V., Boorjian S.A., Thompson R.H., Fergany A.F., Love T.E., Campbell S.C., Comparison of cold and warm ischemia during partial nephrectomy in 660 solitary kidneys reveals predominant role of nonmodifiable factors in determining ultimate renal function, 2011, Journal of Urology, 185, 2, 421, 427 PubMed

Mann S.J., Pickering T.G., Sos T.A., Uzzo R.G., Sarkar S., Friend K., Rackson M.E., Laragh J.H., Captopril renography in the diagnosis of renal artery stenosis: accuracy and limitations, 1991, The American Journal of Medicine, 90, 1, 30, 40 PubMed

Dulaimi E., Uzzo R.G., Greenberg R.E., Al-Saleem T., Cairns P., Detection of Bladder Cancer in Urine by a Tumor Suppressor Gene Hypermethylation Panel, 2004, Clinical Cancer Research, 10, 6, 1887, 1893 PubMed

Kunkle D.A., Crispen P.L., Chen D.Y.T., Greenberg R.E., Uzzo R.G., Enhancing Renal Masses With Zero Net Growth During Active Surveillance, 2007, Journal of Urology, 177, 3, 849, 854 PubMed

Touijer K., Jacqmin D., Kavoussi L.R., Montorsi F., Patard J.J., Rogers C.G., Russo P., Uzzo R.G., Van Poppel H., The Expanding Role of Partial Nephrectomy: A Critical Analysis of Indications, Results, and Complications, 2010, European Urology, 57, 2, 214, 222 PubMed

Additional Publications

My NCBI

Ratings

368 PATIENT SATISFACTION REVIEWS

Our Patient Satisfaction Rating is an average of all responses to care provider related questions from our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more.

OVERALL RATING

5.0 / 5.0

RATINGS BREAKDOWN

  • 4.9
  • 5.0
  • 5.0
  • 5.0
  • 4.9

98 PATIENT COMMENTS

  • 5.0
    September 20, 2021
    Dr Uzzo is awesome and Fox Chase is the best!
  • 5.0
    September 18, 2021
    Dr. Uzzo and his assistant gave me a priceless education that was informative and right on point making me 100% aware of my condition and what I'm facing with no bs ahead of me. These guys care immensely and it shows. Thank you.
  • 5.0
    September 11, 2021
    Most caring and compassionate Dr I ever visited. I would recommend Dr Uzzo to everyone I know
  • 5.0
    September 07, 2021
    What a knowledgeable ands compassionate doctor (Uzzo), and what a comforting team!
  • 5.0
    September 01, 2021
    My Experience with Dr.Uzzo and staff was AWESOME!!!!!!!!!
  • 5.0
    August 31, 2021
    Good experience
  • 5.0
    August 20, 2021
    Thank you Dr Uzzo and staff!
  • 5.0
    August 18, 2021
    Dr. Uzzo and his staff are warm and welcoming. They are so organized and efficient it is a pleasure. Having had kidney cancer it is comforting when the staff is professional and and knows what they are doing. Can't say enough good things about this practice!
  • No Star Ratings Available August 13, 2021
    Dr. Uzzo is one of the BEST doctors I ever met! He is just outstanding!
  • 5.0
    August 13, 2021
    I Love Dr UZZO and his staff !!!
  • 5.0
    August 12, 2021
    Dr. Uzzo and his staff ALWAYS TREAT me with kindness and class.
  • 5.0
    August 10, 2021
    Very professional, respectful, patient, and compassionate - I felt safe, understood, and genuinely cared for.
  • 5.0
    August 06, 2021
    [...] He then called me to discuss my test results. He also needed to contact another dr regarding the results and got back to me very quickly. He is the best doctor I've ever been too and he truly cares about his patients. This is the kind of doctor all patients should have access to when they have serious health issues.
  • 5.0
    August 06, 2021
    Dr. UZZO and his team were excellent!I know that my dad Is In the best hands and he will be OK.Dr. Uzzo gave us detailed action plan and gave us so much confidence in my dad's future. Can't THANK him enough.
  • 5.0
    July 29, 2021
    Dr. Uzzo impressed me by drawing a picture of my kidneys and explained my problem in detail. He took as much time I need to answer my questions. Dr. Uzzo was personable, friendly and very interested in my case to help me. I grade Dr. Uzzo A+.
  • 5.0
    July 28, 2021
    Dr Uzzo is the best ever. He was recommended to me by another doctor, and a former patient. He truly respects me & my health in a manner that has made him #1 with me & his profession.
  • 5.0
    July 28, 2021
    Always feel they have my best interest at heart.
  • No Star Ratings Available July 28, 2021
    Excellent, excellent doctor
  • 5.0
    July 27, 2021
    Dr. Uzzo and staff were very nice and explained everything in detail. I was very comfortable having him as my Dr/surgeon.
  • No Star Ratings Available July 25, 2021
    Good Experience
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