Louis F. Chai, MD

Louis Chai

Assistant Professor

Specialties

  • Thoracic Surgery

Areas of Expertise

Lung Cancer, Esophageal Cancer, Neuroendocrine Tumors, GIST (Gastrointestinal Stromal Tumor), Mesothelioma, GERD & Barrett's Esophagus, Thymoma

Treatment Focus

Esophageal Cancer, Lung Cancer, Neuroendocrine Tumors, Endobronchial Disease, GIST (Gastrointestinal Stromal Tumor), Mesothelioma, GERD & Barrett's Esophagus, Lung Metastases, Thymoma

Distinctions

Clinical Locations

  • Fox Chase Cancer Center
    333 Cottman Avenue
    Philadelphia, PA 19111
    Phone: 888-369-2427
  • Fox Chase Cancer Center - Buckingham
    2365 Heritage Center Drive
    Furlong, PA 18925
    Phone: 888-369-2427

Educational Background

Rutgers Robert Wood Johnson Medical School
Doctor of Medicine-08/2012 - 05/2016

Brandeis University                              
Bachelor of Science in Biology, Magna Cum Laude-08/2008 - 05/2012
Minors: Chemical Biology, Hispanic Studies

 

Certifications

  • American Board of Surgery
  • American Board of Thoracic Surgery - Thoracic and Cardiac Surgery

Honors & Awards

  • Philadelphia Magazine Top Doctors, 2026

Selected Publications

  1. McGovern KA, Tompkins AK, Chai LF, et. al. Behind the curve: International medical graduates in cardiothoracic surgery training. [Submitted to the Journal of Thoracic and Cardiovascular Surgery July 2024]
  2. Parikh MJ, Chai LF, Russo MG, et. al. Dismal adherence to lung cancer screening in a diverse urban population. [Submitted to the Journal of Thoracic and Cardiovascular Surgery July 2024]
  3. Calvelli HR, Chai LF, Nakata JA, et. al. Circumferential pulmonary ossification from lung extraskeletal osteosarcoma with mediastinal shift. Ann Thorac Surg Short Reports. 2024;1:1-4.
  4. Nakata JA, Arif A, Chai LF, et. al. First report of a post-pneumonectomy nocardia empyema. J. Surg Case Rep. 2024 Jan 30;2024(1):rjae002. Doi: 10.1093/jscr/rjae002.eCollection 2024 Jan.
  5. Chai LF, Nahass MM, Iacono SA, et. al. Delayed cardiac tamponade secondary to blast injury from gunshot wound. Trauma Case Rep. 2023 Aug 21:47:100914. Doi: 10.1016/j.tcr.2023.100914.ecollection 2023 Oct.
  6. Chai LF, Hardaway JC, Heatherton KR, et. al. Regional delivery of CAR-T effectively controls tumor growth in colorectal liver metastasis model. J Surg Res. 2022;272;37-50.DOI:101016/j.jss.2021.11.001.
  7. Chai LF, Hardaway JC, Heatherton KR, et. al. Regional delivery of anti-PD-1 agent for colorectal liver metastases improves therapeutic index and anti-tumor activity. Vaccines (Basel). 2021;9(8):807. https://doi.org/10.3390/vaccines9080807
  8. Chai LF, Trebelev AE, and Xiao, G.S. Congenital Common Bile Duct Agenesis: An Extremely Rare Anomaly – Two Case Reports and Review of Literature. J Surg Res (Houst). 2021;4:473-485.
  9. Shankara Narayanan JS, Vicente DA, Ray P, Chai LF, et. al. Pressure-enabled delivery of gemcitabine in an orthotopic pancreatic cancer mouse model. Surgery. Sep 2020;168(3):448-456.
  10. Chai LF, Prince E, Pillarisetty VG, and Katz SC. Challenges in assessing solid tumor responses to immunotherapy. Cancer Gene Ther. Aug 2020;27(7-8):528-538.
  11. Abali EE, Rashid H, Copeland HL, Calt M, DeMaio R, Patel J, Schild S, Phadtare S, Chai L, Ullo M. Shaping Perceptions of Basic Science Education by Utilizing Real Patient Encounters. Medical Science Educator. Apr 2020;30:791-800.
  12. Chai LF and Xiao GS. Choledochoplasty with gallbladder wall free flap: A novel technique for large bile duct defects from Mirizzi Syndome in high-risk patients. A Case Report and Literature Review. Case Rep Surg. Jul 2019;2019:1-5.
  13. Chai L, Ciullo S, and Prasad R. Case Report of Severe Psychiatric Sequelae in a 16-year-old Female Following Resection of a Purely Dopamine-Secreting Ganglioneuroma. Int J Surg Case Rep. July 2019;61:263-266.
  14. Beck T, Deneka AY, Chai L, et. al. An improved method of delivering a sclerosing agent for the treatment of malignant pleural effusion. BMC Cancer. Jun 2019;19:614-621.
  15. Humayun A, Chai LF, Pontell ME, et. al. Pneumoscrotum: Value as an early diagnostic sign of tension pneumothorax in blunt thoracic trauma. Int J Crit Illn Inj Sci. Oct-Dec 2018;8(4):210-213.
  16. Franchini L, Hager S, Edwards DC, Jofre S, Chai L, et. al. Intussusception of the Small Bowel Secondary to Benign Ectopic Prostate Tissue. Urology. Nov 2017; DOI: 10.2016/j.urology.2017/10.026
  17. Blitzer DN, Chai LF, Scott EM, et. al. Chief Resident Dictation of Operative Cases and Its Relationship to American Board of Surgery Examination Performance. Am Surg. Jun 2017;83(6):182-183.
  18. Chai LF, Batista PM, Lavu H. Taking the Lead: A Case Report of a Leiomyoma Causing Duodeno-Duodenal Intussusception and Review of Literature. Case Rep Pancreat Cancer. Apr 2016;2(1):19-22.

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