Fox Chase Cancer Center News

Fox Chase Researchers Discover Novel Role of the NEDD9 Gene in Early Stages of Breast Cancer

PHILADELPHIA, PA (January 14, 2013)—Breast cancer is the second leading cause of cancer deaths among women in the United States. Many of these deaths occur when there is an initial diagnosis of invasive or metastatic disease. A protein called NEDD9—which regulates cell migration, division and survival—has been linked to tumor invasion and metastasis in a variety of cancers. Researchers at Fox Chase Cancer Center have now shown that NEDD9 plays a surprising role in the early stages of breast tumor development by controlling the growth of progenitor cells that give rise to tumors.

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Researchers Develop Novel 3D Culture System for Inflammatory Breast Cancer

SAN ANTONIO, TX (December 8, 2012)—Inflammatory breast cancer (IBC) is a very rare and aggressive disease that progresses rapidly and is associated with a very low survival rate. To understand how this type of cancer spreads, it's crucial to characterize the interactions between cancer cells and their 3D environment. Researchers at Fox Chase Cancer Center have developed a novel, 3D culture system that mimics the environment surrounding these cancer cells. This model could be used to test new anticancer drugs capable of inhibiting the spread of IBC tumors.

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Protein Tied to Cancer Drug Resistance in Mice

SAN ANTONIO, TX (December 7, 2012)—Blocking a specific protein renders tumors more vulnerable to treatment in mice, suggesting new therapies could eventually achieve the same in humans, according to new research from Fox Chase Cancer Center to be presented at the 2012 CTRC-AACR San Antonio Breast Cancer Symposium on Friday, December 7, 2012.

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Attitudes Predict Ability to Follow Post-Treatment Advice

SAN ANTONIO, TX (December 6, 2012)—Women are more likely to follow experts' advice on how to reduce their risk of an important side effect of breast cancer surgery—like lymphedema—if they feel confident in their abilities and know how to manage stress, according to new research from Fox Chase Cancer Center to be presented at the 2012 CTRC-AACR San Antonio Breast Cancer Symposium on Saturday, December 8, 2012.

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Leading Cancer Center Administrator/Scientist Richard I. Fisher, MD, To Join Fox Chase Cancer Center and Temple University School of Medicine

PHILADELPHIA, PA (December 3, 2012) – On March 1, 2013, leading cancer center administrator and nationally recognized hematology/oncology expert Richard I. Fisher, MD, will assume a set of vital leadership roles at Fox Chase Cancer Center, a member of the Temple University Health System, and Temple University School of Medicine.

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