Finding by Fox Chase Researchers That YAP1 Molecule is Essential to Development of Gastruloids Using Embryonic Stem Cells May Have Implications for Cancer
PHILADELPHIA (February 17, 2022)—Researchers at Fox Chase Cancer Center have discovered that the Hippo signaling effector YAP1 is a master regulator of Nodal signaling in human embryonic stem cells (hESCs) for a process essential to human development.