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Lili Chen, PhD

Lili Chen, PhD

Clinical Locations

Primary Location

Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111

About

Professor

Clinical Physicist

Research Program

 
Comparison of DVHs for PTV, Rectum and Bladder between CT- and MRI-based IMRT plans
Comparison of isodose distributions between CT-and MRI-based IMRT plans
MR images showing a prostate tumor in vivo study

 

Education and Training

Educational Background

  • PhD, Medical Physics and Biophysics Physics Dept, Royal Marsden Hosp/Institute of Cancer Research, University of London, London, U.K., 1994
  • MD, Medical University of Shanghai, Shanghai, China, 1982

Honors & Awards

  • Fellowship Award AAPM, 2013;
  • Who’s Who in America, 2013;
  • Best paper in Physics (Therapy), Medical Physics, 2012;
  • Best paper in Physics (Imaging), Medical Physics, 2012;
  • AAPM/IPEM Medical Physics Travel Grant, 2009;
  • LAP Award of Excellence for best radiation oncology article, ACMP, 2005
Research Profile

Research Program

Research Interests

  • Linac based SBRT
  • Radiodynamic therapy and PET MR implementation
  • Non-thermal HIFU for breast cancer
  • Implementation of MRI-based treatment planning for 3DCRT and IMRT (project leader)
  • MRS applications for radiotherapy (team member)
  • MR-guided HIFU for cancer surgery/therapy (project leader)
  • MR-guided HIFU to enhance drug delivery (project leader)

Lab Overview

The lab uses cancer animal models, in particular prostate, head and neck, breast, lung, pancreatic, ovarian and other diseases for understanding pathogenesis and developing novel therapeutic approaches. Staff performs cancer treatment studies including radiotherapy, radio-dynamic therapy, gene therapy, chemotherapy, nanotherapy, and MR-guided high intensity focused ultrasound therapy.

  • Jian-Hua Ren, Visiting Physicist
  • Peng Zhang, Visiting Radiation Oncologist
  • Chunting Wang, Visiting Scientist
  • Binh Nguyen, Visiting Student
  • Jennifer Zhu, Visiting Research Assistant
  • Elan Jones, Visiting Student
  • Xiu Xu, Visiting Research Assistant
Lab Staff

Dusica Cvetkovic, MD, MS

Research Associate

Room: W230
215-728-3661
Dusica.Cvetkovic@fccc.edu

Theresa Richardson, RT, (CT), (MR)

Simulation Therapist

Room: P0143
215-728-2581
Theresa.Richardson@fccc.edu

Lorraine Medoro

Administrative Assistant

Room: P1096
215-728-3043
Lorraine.Medoro@fccc.edu

Roohi Gupta, PhD

Medical Physics Resident

Room: P0103
215-728-1426
Roohi.Gupta@fccc.edu

Bin Wang, PhD

Medical Physics Resident

Room: P0103
215-728-1426
Bin.Wang@fccc.edu

Wei He

Visiting Scientist

Room: P0103
wei_he@csu.edu.cn
Publications

Selected Publications

Xu Q., Tong X., Lin M., Chen X., ElDib A., Lin T., Chen L., Ma C.C., Time and frequency to observe fiducial markers in mlc-modulated fields during prostate imrt/vmat beam delivery. Phys Med. 76: 142-149, 2020. PMC7528608. https://www.ncbi.nlm.nih.gov/pubmed/32679409.

Shan G., Hu W., Chen L., Price R.A., Ma C.C., Dosimetric evaluation of image-guided radiation therapy for prostate cancer. Med Dosim. 46(2): 117-126, 2021. https://www.ncbi.nlm.nih.gov/pubmed/33020024.

Panetta J.V., Cvetkovic D., Chen X., Chen L., Ma C.C., Radiodynamic therapy using 15-mv radiation combined with 5-aminolevulinic acid and carbamide peroxide for prostate cancer in vivo. Phys Med Biol. 65(16): 165008, 2020. PMC8409498. https://www.ncbi.nlm.nih.gov/pubmed/32464613.

Ma C-M, Chen X, Cvetkovic D, Chen L, An In-Vivo Investigation of the Therapeutic Effect of Pulsed Focused Ultrasound on Tumor Growth, Med. Phys. (2014) 41, 122901; doi: 10.1118/1.4901352. PubMed

Gupta R, Cvetkovic D, Ma CM, Chen L (2014) Targeted Approach for Prostate Cancer Treatment: Synthesis and Characterization of Docetaxel-Loaded Perfluorocarbon Nanodroplets. J Cancer Sci Clin Oncol 1(1): 102. doi: 10.15744/2394-6520.1.102. 

Chen X, Cvetkovic D, Ma C-M, Chen L Quantitative Study of Focused Ultrasound Enhanced Doxorubicin Delivery to Prostate Tumor In Vivo with MRI guidance Med. Phys. 39 2780-2786 (2012). PubMed

Mu Z, Ma C-M, Chen X, Pollack A and Chen L. MR Guided Pulsed High Intensity Focused Ultrasound Enhancement of Docetaxel Combined with Radiotherapy for Prostate Cancer Treatment Phys. Med. Biol. 57 535–545 (2012). PubMed

Chen L, Mu Z, Hachem P, Ma C-M and Pollack A. MR-guided focused ultrasound: enhancement of intratumoral uptake of [3H]-docetaxel in vivo Phys. Med. Biol., 55: 7399-7410 (2010). PubMed

Chen L, Paskalev K, Xu X, Zhu J, Feigenberg S, Pollack A, Hu W, Ma C-M. Prostate Cancer IMRT: Rectal Dose Variation During the Course of the Treatment in Image Guided Radiation Therapy. Radiotherapy and Oncology, 95: 198-202 (2010). PubMed

Chen L, Nguyen T-B, Jones E, Chen Z, Luo W, Wang L, Price RA, Pollack A and Ma C-M. MRI-Based Treatment Planning for Prostate IMRT: Creation of Digitally Reconstructed Radiographs (DRR). International Journal of Radiation Oncology Biology Physics 68:(3): 903-11 (2007). PubMed... Expand

Additional Publications

My NCBI

Lili Chen, PhD

Clinical Locations

Primary Location

Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111

Contact Information

Lili.Chen@fccc.edu
Office Phone: 215-728-3003
Fax: 215-728-4789
Pager: 5600-0021
Office: CRP-LL - P0079

Professor

Clinical Physicist

Research Program

 
Comparison of DVHs for PTV, Rectum and Bladder between CT- and MRI-based IMRT plans
Comparison of isodose distributions between CT-and MRI-based IMRT plans
MR images showing a prostate tumor in vivo study

 

Education

Educational Background

  • PhD, Medical Physics and Biophysics Physics Dept, Royal Marsden Hosp/Institute of Cancer Research, University of London, London, U.K., 1994
  • MD, Medical University of Shanghai, Shanghai, China, 1982

Honors & Awards

  • Fellowship Award AAPM, 2013;
  • Who’s Who in America, 2013;
  • Best paper in Physics (Therapy), Medical Physics, 2012;
  • Best paper in Physics (Imaging), Medical Physics, 2012;
  • AAPM/IPEM Medical Physics Travel Grant, 2009;
  • LAP Award of Excellence for best radiation oncology article, ACMP, 2005

Research Profile

Research Interests

  • Linac based SBRT
  • Radiodynamic therapy and PET MR implementation
  • Non-thermal HIFU for breast cancer
  • Implementation of MRI-based treatment planning for 3DCRT and IMRT (project leader)
  • MRS applications for radiotherapy (team member)
  • MR-guided HIFU for cancer surgery/therapy (project leader)
  • MR-guided HIFU to enhance drug delivery (project leader)

Lab Overview

The lab uses cancer animal models, in particular prostate, head and neck, breast, lung, pancreatic, ovarian and other diseases for understanding pathogenesis and developing novel therapeutic approaches. Staff performs cancer treatment studies including radiotherapy, radio-dynamic therapy, gene therapy, chemotherapy, nanotherapy, and MR-guided high intensity focused ultrasound therapy.

  • Jian-Hua Ren, Visiting Physicist
  • Peng Zhang, Visiting Radiation Oncologist
  • Chunting Wang, Visiting Scientist
  • Binh Nguyen, Visiting Student
  • Jennifer Zhu, Visiting Research Assistant
  • Elan Jones, Visiting Student
  • Xiu Xu, Visiting Research Assistant

Lab Staff

Dusica Cvetkovic, MD, MS

Research Associate

Room: W230
215-728-3661
Dusica.Cvetkovic@fccc.edu

Theresa Richardson, RT, (CT), (MR)

Simulation Therapist

Room: P0143
215-728-2581
Theresa.Richardson@fccc.edu

Lorraine Medoro

Administrative Assistant

Room: P1096
215-728-3043
Lorraine.Medoro@fccc.edu

Roohi Gupta, PhD

Medical Physics Resident

Room: P0103
215-728-1426
Roohi.Gupta@fccc.edu

Bin Wang, PhD

Medical Physics Resident

Room: P0103
215-728-1426
Bin.Wang@fccc.edu

Wei He

Visiting Scientist

Room: P0103
wei_he@csu.edu.cn

Publications

Selected Publications

Xu Q., Tong X., Lin M., Chen X., ElDib A., Lin T., Chen L., Ma C.C., Time and frequency to observe fiducial markers in mlc-modulated fields during prostate imrt/vmat beam delivery. Phys Med. 76: 142-149, 2020. PMC7528608. https://www.ncbi.nlm.nih.gov/pubmed/32679409.

Shan G., Hu W., Chen L., Price R.A., Ma C.C., Dosimetric evaluation of image-guided radiation therapy for prostate cancer. Med Dosim. 46(2): 117-126, 2021. https://www.ncbi.nlm.nih.gov/pubmed/33020024.

Panetta J.V., Cvetkovic D., Chen X., Chen L., Ma C.C., Radiodynamic therapy using 15-mv radiation combined with 5-aminolevulinic acid and carbamide peroxide for prostate cancer in vivo. Phys Med Biol. 65(16): 165008, 2020. PMC8409498. https://www.ncbi.nlm.nih.gov/pubmed/32464613.

Ma C-M, Chen X, Cvetkovic D, Chen L, An In-Vivo Investigation of the Therapeutic Effect of Pulsed Focused Ultrasound on Tumor Growth, Med. Phys. (2014) 41, 122901; doi: 10.1118/1.4901352. PubMed

Gupta R, Cvetkovic D, Ma CM, Chen L (2014) Targeted Approach for Prostate Cancer Treatment: Synthesis and Characterization of Docetaxel-Loaded Perfluorocarbon Nanodroplets. J Cancer Sci Clin Oncol 1(1): 102. doi: 10.15744/2394-6520.1.102. 

Chen X, Cvetkovic D, Ma C-M, Chen L Quantitative Study of Focused Ultrasound Enhanced Doxorubicin Delivery to Prostate Tumor In Vivo with MRI guidance Med. Phys. 39 2780-2786 (2012). PubMed

Mu Z, Ma C-M, Chen X, Pollack A and Chen L. MR Guided Pulsed High Intensity Focused Ultrasound Enhancement of Docetaxel Combined with Radiotherapy for Prostate Cancer Treatment Phys. Med. Biol. 57 535–545 (2012). PubMed

Chen L, Mu Z, Hachem P, Ma C-M and Pollack A. MR-guided focused ultrasound: enhancement of intratumoral uptake of [3H]-docetaxel in vivo Phys. Med. Biol., 55: 7399-7410 (2010). PubMed

Chen L, Paskalev K, Xu X, Zhu J, Feigenberg S, Pollack A, Hu W, Ma C-M. Prostate Cancer IMRT: Rectal Dose Variation During the Course of the Treatment in Image Guided Radiation Therapy. Radiotherapy and Oncology, 95: 198-202 (2010). PubMed

Chen L, Nguyen T-B, Jones E, Chen Z, Luo W, Wang L, Price RA, Pollack A and Ma C-M. MRI-Based Treatment Planning for Prostate IMRT: Creation of Digitally Reconstructed Radiographs (DRR). International Journal of Radiation Oncology Biology Physics 68:(3): 903-11 (2007). PubMed... Expand

Additional Publications

My NCBI

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