Fox Chase Cancer Center News

Local Student Raises Money for Cancer Research through Fox Chase's Charity Dog-Walk

PHILADELPHIA (October 10, 2010) – When it came time for Ariel Silverman, a 12-year-old Bat Mitzvah candidate from Upper Dublin, to choose her mitzvah project, the choice was clear. She decided to combine her love of dogs with her willingness to support cancer research by raising money for Fox Chase Cancer Center’s annual charity dog-walk—Paws for the Cause.

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'Synthetic Lethality' Strategy Improves Molecularly Targeted Cancer Therapy

PHILADELPHIA (September 21, 2010) – Molecularly targeted therapies can reduce tumors rapidly. However, not all tumors respond to the drugs, and even those that do often develop resistance over time. Looking for a way to combat the problem of resistance, researchers at Fox Chase Cancer Center hypothesized that hitting already weakened cancer cells with a second targeted agent could kill them—but only if it was the right second agent.

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Fox Chase Researchers Uncover Activation Signal for Aurora-A Oncogene: Discovery May Lead to More Potent Drug Combinations

PHILADELPHIA (September 7, 2010) - Aurora-A kinase (AurA) is an enzyme that is hyperactive in many cancers and drives tumor cell proliferation. Several AurA inhibitors are currently being tested in clinical trials to see if they slow tumor growth. Now, researchers in the Developmental Therapeutics Program at Fox Chase Cancer Center have identified an activation signal for AurA. 

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Rectal Cancer Rates Are Rising in Young Individuals

PHILADELPHIA (August 23, 2010) –A new analysis has found that while colon cancer rates have remained steady over the past several decades among people under the age of 40, rectal cancer rates are increasing in this population across races and in both sexes. 

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