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The Cancer Genome Institute at Fox Chase is Among the First in the Nation to Offer Advanced Cancer Patients a Blueprint of Their Cancer Genes

Blueprint could help guide treatment for patients who have exhausted all other options

Cancer Genome InstitutePHILADELPHIA (January 7, 2013)—Fox Chase Cancer Center, a National Cancer Institute-designated Comprehensive Cancer Center, is now offering patients with advanced cancer a cutting-edge clinical test that will provide them with a unique blueprint of their cancer genes.

The new clinical test, known as CancerCode-45TM, evaluates an individual’s tumor for genetic alterations in a select group of 45 genes and gives physicians the opportunity to look at the alterations and be even more precise when choosing a course of treatment. The test is being offered through the Cancer Genome Institute at Fox Chase—one of only a few centers in the nation to offer such pioneering technology in cancer molecular diagnostics.

“Gaining insight like this into the DNA of a specific tumor is the next step in transforming cancer care and prevailing over cancer,” says Michael V. Seiden, MD, PhD, president and CEO of Fox Chase. “We are very excited to be offering this innovative test at our Center and look forward to the ways it will enhance the care we provide our patients.”

Using leading-edge technology, physicians and scientists at Fox Chase are able to perform the CancerCode-45 test and analyze the genetic information in the DNA of a patient’s tumor to find changes that are crucial to supporting their cancer.  This genetic analysis will examine multiple alterations in 45 cancer-related genes and provide a report to the patient’s treating physician.

Prior to the CancerCode-45 test being performed, patients will need to see a Fox Chase physician to provide information about their background, medical history, current medications, and ability to perform daily activities. In addition, the physician will need to take a blood sample and a sample of the tumor (which can come from a previous surgery or biopsy that the patient might have had). It takes about 20 working days to get each patient’s test results.  

“Not every patient will benefit from this test, but for some it could very well change their entire course of treatment and significantly prolong their life,” says Jeff Boyd, PhD, executive director of the Cancer Genome Institute at Fox Chase. “At the very least, the results may help physicians decide how to treat their patients with advanced cancer—whether by suggesting they use a particular type of drug or not use a particular type of drug or by allowing them to take part in clinical trials of new medications guided by their tumor’s genetic profile.”

To learn more about this new clinical test, please call 1-888-FOX CHASE or (1-888-369-2427).


Fox Chase Cancer Center, part of the Temple University Health System, is one of the leading cancer research and treatment centers in the United States. Founded in 1904 in Philadelphia as one of the nation’s first cancer hospitals, Fox Chase was also among the first institutions to be designated a National Cancer Institute Comprehensive Cancer Center in 1974. Fox Chase researchers have won the highest awards in their fields, including two Nobel Prizes. Fox Chase physicians are also routinely recognized in national rankings, and the Center’s nursing program has received the Magnet recognition for excellence four consecutive times. Today, Fox Chase conducts a broad array of nationally competitive basic, translational, and clinical research, with special programs in cancer prevention, detection, survivorship, and community outreach.  For more information, call 1-888-FOX CHASE or (1-888-369-2427).

Media inquiries only, please contact Diana Quattrone at 215-728-7784.

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