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Genetic Monitoring Facility

Director:   David L. Wiest, PhD
215-728-2966
David.Wiest@fccc.edu
Administrative Manager / Contact: Annmarie T. Pimble, AS
Annmarie.Pimble@fccc.edu
215-728-3623
Reimann R271
Technical Services Supervisor: Mark A. Tigue, BS, RLATG
Technical Services Supervisor, LAF
215-728-2178
Mark.Tigue@fccc.edu
Location & Phone: Reimann R260
215-728-2510 or 215-728-2178
Pricing & Scheduling: Contact Annmarie Pimble for pricing and scheduling.

The Genetic Monitoring Facility (GMF) functions to protect the genetic integrity of the inbred strains and transgenic lines of rodents utilized in the various research programs at Fox Chase Cancer Center.

Rodents used in today's biomedical research must not only be free of disease that may influence experimental results, but also be well-defined in terms of their genetic makeup. This is especially true with the increasing use of transgenic mice in most areas of biomedical research. The majority of research, involving laboratory animals, conducted at the Center involves the use of various genetic systems and large numbers of genetically- modified rodents. Rodents used in today's biomedical research must not only be free of disease that may influence experimental results, but also be well defined in terms of their genetic makeup. This is especially true with the increasing use of genetically modified mice in most areas of biomedical research. Consequently, the Genetic Monitoring Facility functions to protect and ensure the genetic integrity of the inbred strains and transgenic lines of rodents utilized in the various research programs at the Center.

The facility manages the breeding of an average of 200 lines of inbred, mutant or genetically-modified mice for Fox Chase investigators. The daily operation of the breeding colonies is handled by personnel trained and experienced in genetic management and record keeping. In addition, the Laboratory Animal Facility (LAF) director and Technical Services Supervisor continuously monitor the activities in these colonies.

This facility suppports Fox Chase Cancer Center's Cancer Center Support Grant (CCSG) from the National Cancer Institute.

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