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Fox Chase Cancer Center News

April 6, 2020

Fox Chase Researchers Plan Study for Addressing Sexual Concerns in Breast Cancer Patients

PHILADELPHIA (April 6, 2020)—A recently published protocol paper by researchers at Fox Chase Cancer Center describes a new trial evaluating a couple-based intervention program designed to improve sexual relationships for breast cancer survivors. The goal of the study is to see whether a four-session couple-based intervention program done over the phone can help improve sexual function for breast cancer survivors.

March 30, 2020

Journal Article From Fox Chase Clinicians Offers Advice on Managing Cancer Care During COVID-19 Pandemic

PHILADELPHIA (March 30, 2020)—A group of Fox Chase Cancer Center clinicians featured their expertise in an article that advised physicians on the best approach to take with patients who have been diagnosed or are currently under treatment for cancer during the ongoing COVID-19 pandemic.

Catherine Tuite, MD
March 27, 2020

Unnecessary Breast Biopsies Could be Avoided Using Updated Assessment of Clustered Microcyst Imaging

PHILADELPHIA (March 27, 2020) —  A retrospective study of lesions classified as clustered microcysts between 2005 and 2015 found no malignancies in any of the 196 lesions.

Krais and Johnson are lead authors of the study.
March 26, 2020

Study Finds Excess Production of RNF168 Protein May Spur Development of BRCA-Mutated Cancers

PHILADELPHIA (March 26, 2020)— When there is an absence of BRCA1, excessive RNF168 expression may drive break-induced replication and contribute to mutational characteristics seen in BRCA1-mutated cancers.

John J. Krais, PhD, a postdoctoral associate in the Molecular Therapeutics program.
March 25, 2020

Study Suggests Disrupting DNA Repair Signaling Could Block Cancer Growth

PHILADELPHIA (March 25, 2020)—A study by researchers at Fox Chase Cancer Center published today found that the RNF168 signaling pathway is critical for preventing the growth of BRCA1 mutant cancers, and that new drugs, designed to restore this pathway, could be effective for treating cancers with BRCA1 gene mutations.

It turns out that ZBP1 sees Z-RNA, a new form of RNA produced by influenza virus.
March 19, 2020

New Influenza Findings Could Have Key Impact on Cancer Therapies

PHILADELPHIA (March 19, 2020) – Researchers at the Fox Chase Cancer Center have clarified a fundamental host defense mechanism that detects the presence of influenza virus and rapidly destroys infected cells. “Influenza virus Z-RNAs induce ZBP1-mediated necroptosis” was published in Cell.

Efrat Dotan, MD
March 17, 2020

Study Suggests Link Between BMI, Nutritional Markers, and Chemotherapy Toxicity in Older Adults With Tumors

PHILADELPHIA (March 17, 2020) — A study led by a researcher at Fox Chase Cancer Center concluded that a combination of body mass index (BMI) and levels of albumin can predict how well older adults with cancer will be able to tolerate the side effects of chemotherapy.

Study suggests genomic profiles measured through circulating free DNA (cfDNA) in the blood of breast cancer patients may provide a more effective way to treat cancer and track its progression.
March 13, 2020

Fox Chase Researchers Study ‘Liquid Biopsies’ as Possible Method for Improved Cancer Detection and Monitoring Progression

PHILADELPHIA (March 13, 2020)—Fox Chase Cancer Center researchers have published a study suggesting that genomic profiles measured through circulating free DNA (cfDNA) in the blood of breast cancer patients may provide a more effective way to treat cancer and track its progression.

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