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Miriam N. Lango, MD, FACS

Miriam Lango, MD, FACS

Clinical Locations

Primary Location

Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111

About

Associate Professor
Medical Director, Speech Pathology Service

Treatment Focus

  • Salivary gland tumors; paragangliomas; sinonasal malignancies and skull base tumors; neck masses
  • Voice and swallowing disorders
  • Transoral robotic surgery and transoral laser microsurgery
  • Organ preservation larynx surgery
  • Thyroid and parathyroid surgery
  • Anterior skull base and sinus surgery
  • Head and neck reconstructive surgery

Key Awards

Philadelphia magazine Top Docs, 2012-2015

Treatment Philosophy

I joined the department of surgical oncology at Fox Chase Cancer Center in 2004 as a head and neck surgeon, as well as an ear, nose and throat specialist. In my practice, I have a special interest in tumors located in the upper aerodigestive tract, thyroid, skull base and sinonasal tract. My particular area of treatment expertise is minimally-invasive and transoral surgery.

It is an exciting time to work in my field. Traditionally, cancers of the head and neck (mouth, tongue, larynx and pharynx) required radical surgery followed by radiation. Surgery frequently robbed patients of the ability to speak intelligibly, swallow or eat solid food. Today, many more options are available. I believe the goal of treatment is to cure cancer while preserving as much quality of life as possible. Technological advances in surgery have made this possible for many patients.

Today, surgeons can safely remove deeply seated tumors with little collateral damage to normal tissues by using minimally-invasive surgical techniques. Since not every tumor is appropriately treated using minimally-invasive approaches, it is important for each patient to undergo a comprehensive evaluation before starting treatment. For some patients, surgery may not be a good option. Radiation with or without chemotherapy may be more effective or provide a better quality of life in the long term.

Because all patients and tumors are different, decision-making can be complex. Typically, a patient who is evaluated at Fox Chase Cancer Center will see physicians from several specialties including surgical oncology, radiation oncology and medical oncology. I believe that this type of multispecialty evaluation is important in determining the best treatment for each patient. Armed with state-of-the-art information, our patients can make informed decisions about their care.

I believe that patient quality of life has been a relatively neglected area of study. Novel treatment approaches have the potential to diminish treatment-related side effects. I am currently the principal investigator of a clinical trial to measure swallowing function and quality of life in head and neck cancer patients. I hope that what we learn will be used to help guide treatment recommendations for our patients.

Follow on Twitter: @FCCCSurgOnc

Education, Training & Credentials

Educational Background

  • Fellowship, Head and Neck Oncologic and Microvascular Reconstructive Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA
  • Residency, Otolaryngology/Head and Neck Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA
  • New York University School of Medicine, New York, NY, 1996

Certifications

  • American Board of Otolaryngology/Head and Neck Surgery

Memberships

  • American Academy of Otolaryngology
  • American Association of Endocrine Surgeons
  • American College of Surgeons
  • American Head and Neck Society
  • American Society of Clinical Oncology
  • American Thyroid Association
  • Eastern Cooperative Oncology Study Group

Honors & Awards

  • Philadelphia magazine Top Docs, 2012-2015
Patient Stories

Charlie Osborne

Head & Neck Cancer

Charlie Osborne

Head & Neck Cancer

Charlie Osborne quit smoking over 20 years ago because he noticed people getting annoyed with smokers — and was no longer allowed to smoke at work. He also knew it was a health hazard. By quitting the habit, Charlie thought his chances of developing cancer had been diminished. Unfortunately, that was not the case.

In early 2005, at the age of 52, Charlie experienced problems swallowing and had a blocked windpipe. He had trouble sleeping and began losing weight.

Stephen Meier

Head & Neck Cancer

Stephen Meier

Head & Neck Cancer

Stephen Meier is proud of his Philadelphia roots. This Somerton resident speaks with a decidedly Philly cadence, an especially notable feature since he had his larynx removed in 2012 when he was 59.

Paul Reitano

Head & Neck Cancer

Paul Reitano

Head & Neck Cancer

Paul Reitano was in very good health prior to his cancer diagnosis in 2012. An avid participant of martial arts and working-out, he is fortunate to have two successful careers: his day job is working as an engineer’s assistant for the Delaware Valley Regional Planning Commission, and his second career is as a photographer of both of corporate and social events. But his world turned upside down in October, 2012, when Paul felt a lump in the left side of his neck.

Michael Sours

Head & Neck Cancer;  Skin Cancer

Michael Sours

Head & Neck Cancer;  Skin Cancer

Squamous Cell Carcinoma

In 2007, when he was in his late sixties, Michael Sours discovered a lump on the right side of his neck while taking a shower. He waited a few days to see if the lump would disappear, but it did not. With a personal history of several diagnoses of skin cancer, Michael took his health care seriously and scheduled an appointment with an otolaryngologist (ear, nose and throat doctor). The physician performed a biopsy and removed the enlarged lymph node. The results were alarming – Michael was diagnosed with squamous cell carcinoma.

Richard Millham

Skin Cancer

Richard Millham

Skin Cancer

When he started running in 1989 at the age of 55, Dick Millham thought he was taking strides towards a healthier lifestyle. And while he was indeed doing his heart and body good, the fact that he ran in the heat of summer without the benefit of hat, shirt or sunscreen eventually caught up with him. “I always thought that my olive skin meant I wouldn’t have a problem with the sun or skin cancer,” says Dick.

Research Profile

Research Interests

  • Thyroid cancer
  • Head and neck cancer
  • Melanoma
  • Quality of Life/ Outcomes research
Publications

Selected Publications

Lango MN, Galloway T, Mehra R, Ebersole B, Liu J, Moran K, Ridge JA. Impact of baseline patient-reported dysphagia on acute gastrostomy placement in patients with head and neck squamous cell carcinoma undergoing definitive radiation. Head Neck. 2015 Aug 15. [Epub ahead of print]

Cracchiolo J, Ridge JA, Egleston B, Lango M. Practice arrangement and Medicare physician payment in otolaryngology. Otolaryngol Head Neck Surg. 2015 Jun;152(6):979-87.

Aaron H, Azadarmaki R, Lango MN. Unilateral Vocal Cord Motion Impairment After 1 Dose of Vincristine: Case Report and Literature Review. Am J Ther. 2015 May 27.[Epub ahead of print] PubMed PMID: 25738569.

Arrangoiz R, Galloway TJ, Papavasiliou P, Ridge JA, Lango MN. Metastatic cervical carcinoma from an unknown primary: literature review. Ear Nose Throat J. 2014 Apr-May;93(4-5):E1-10. Review.

Lango MN, Egleston B, Fang C, Burtness B, Galloway T, Liu J, Mehra R, Ebersole B, Moran K, Ridge JA. Baseline health perceptions, dysphagia, and survival in patients with head and neck cancer. Cancer. 2014 Mar 15;120(6):840-7.

Tejani MA, Galloway TJ, Lango M, Ridge JA, von Mehren M. Head and neck sarcomas: a comprehensive cancer center experience. Cancers (Basel). 2013 Jul 15;5(3):890-900.

Azadarmaki R, Lango MN. Malignant transformation of respiratory papillomatosis in a solid-organ transplant patient: case report and literature review. Ann Otol Rhinol Laryngol. 2013 Jul;122(7):457-60. Review.

Lango M, Flieder D, Arrangoiz R, Veloski C, Yu JQ, Li T, Burtness B, Mehra R, Galloway T, Ridge JA. Extranodal extension of metastatic papillary thyroid carcinoma: correlation with biochemical endpoints, nodal persistence, and systemic disease progression. Thyroid. 2013 Sep;23(9):1099-105.

Galloway TJ, Lango MN, Burtness B, Mehra R, Ruth K, Ridge JA. Unilateral neck therapy in the human papillomavirus ERA: accepted regional spread patterns. Head Neck. 2013 Feb;35(2):160-4.

Andrews G, Lango M, Cohen R, Feigenberg S, Burtness B, Mehra R, Ahmed S, Nicolaou N, Gaughan J, Ridge JA. Nonsurgical management of oropharyngeal, laryngeal, and hypopharyngeal cancer: the Fox Chase Cancer Center experience. Head Neck. 2011 Oct;33(10):1433-40.

Lango MN, Topham NS, Perlis CS, Flieder DB, Weaver MW, Turaka A, Patel SA, Ridge JA. Surgery in the multimodality treatment of sinonasal malignancies. Curr Probl Cancer. 2010 Sep-Oct;34(5):304-21. Review.

Lango MN, Egleston B, Ende K, Feigenberg S, D'Ambrosio DJ, Cohen RB, Ahmad S, Nicolaou N, Ridge JA. Impact of neck dissection on long-term feeding tube dependence in patients with head and neck cancer treated with primary radiation or chemoradiation. Head Neck. 2010 Mar;32(3):341-7.

Lango M, Ridge JA. Lymph node dissection for thyroid cancer. Duh Q-Y, Clark OH, Kebebew E, editors. In: Atlas of Endocrine Surgical Techniques. Philadelphia: Saunders; 2010. p. 72-85. 

Lango MN, Andrews GA, Ahmad S, Feigenberg S, Tuluc M, Gaughan J, Ridge JA. Postradiotherapy neck dissection for head and neck squamous cell carcinoma: pattern of pathologic residual carcinoma and prognosis. Head Neck. 2009 Mar;31(3):328-37.

Lango MN, Dyer KF, Lui VW, Gooding WE, Gubish C, Siegfried JM, Grandis JR. Gastrin-releasing peptide receptor-mediated autocrine growth in squamous cell carcinoma of the head and neck. J Natl Cancer Inst. 2002 Mar 6;94(5):375-83.

Additional Publications

My NCBI