Jonathan D. Cheng, MD

Jonathan Cheng, MD
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Attending Physician

Treatment Philosophy

My practice is focused on the diagnosis, treatment and prevention of gastrointestinal malignancies. This allows me to be well versed in the multitude of complex medical, emotional and social issues facing patients. I use this experience to guide patients through the range of therapeutic options, including the latest research findings and newest clinical trials.

By understanding what patients know about themselves and their preferences, we can arrive at an appropriate treatment approach for each patient's situation. The specialized disease-focused teams at Fox Chase Cancer Center, which include pathologists, gastroenterologists, oncologic surgeons and radiation oncologists, all focused on gastrointestinal malignancies, allow for a tremendous depth of care to our patients.

Since joining Fox Chase Cancer Center in 1999, my research has focused on the importance of the surrounding support cells called stroma that tumors utilize to grow and metastasize. This has led to clinical trials investigating this novel approach using new agents that inhibit the tumor stroma in colorectal, pancreas, esophageal and gastric cancers.

Educational Background

  • Fellow, Medical Oncology, Roswell Park Cancer Institute, Buffalo, NY
  • Fellow, Gastrointestinal Oncology, Roswell Park Cancer Institute, Buffalo, NY
  • Fellow, Laboratory Research, Fox Chase Cancer Center, Philadelphia, PA
  • Resident, Internal Medicine, University of Minnesota, Minneapolis, MN
  • MD, University of Minnesota Medical School, Minneapolis, MN, 1992


  • American Board of Internal Medicine
  • Medical Oncology 


  • American Society of Clinical Oncology
  • American Association for Cancer Research 

Research Interests

Tumor Microenvironment

The following ratings and reviews are based on verified feedback collected from independently administered patient experience surveys. The ratings and comments submitted by patients reflect their own views and opinions. Patient identities are withheld to ensure confidentiality and privacy. Learn more about our Patient Experience Ratings.

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