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John Hoffman, MD, FACS

John Hoffman, MD, FACS

Clinical Locations

Primary Location

Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111

Chief, Pancreaticobiliary Service
Marvin S. Greenberg, MD, Chair in Pancreatic Cancer Surgery 

Treatment Philosophy

I joined Fox Chase in 1986. I entered the field of surgical oncology because it was the field in the mid-1970s that was most interesting to me and the one that needed the most work. When my father developed a metastatic colon cancer in 1978, I was given further motivation to work in this field. This happened when I was in my first year of Surgical Oncology Fellowship at Memorial Sloan-Kettering Cancer Center. While there, I took an extra year of training in pancreatic and liver surgery.

My first job after fellowship was as the Director of the Division of Surgical Oncology at Loyola University School of Medicine in Maywood, Illinois. After 6 years there, I moved to Fox Chase, where I could concentrate fully on the treatment and the advancement of treatment for cancer. Since that time, I have seen many wonderful advances in the treatment of many cancers.

Much of my time and effort over the past 30 years here have been spent on the development of the treatment for pancreatic cancer. While we still have a long way to go before this scourge is defeated, I can remember when doctors were against any treatment, surgery or other, for pancreatic cancer because it was so hopeless. We now have many different drugs that have activity against the cancer and are in the process of testing which ones are optimal, both in concert with surgical resection, or alone (when resection is neither possible nor feasible). I still see patients from whom I've resected pancreatic cancer 10 to 18 years ago!

Every day at Fox Chase is a pleasure for me. The entire hospital is composed of people who recognize that every patient is a special cancer fighter, and therefore they all are treated as unique individuals. It is this total institutional dedication, as well as my 30 years of cancer treatment experience, that should convince you to let us take care of you.

Follow on Twitter: @FCCCSurgOnc

Educational Background

  • Fellow, Surgical Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY 
  • Resident, General Surgery, Virginia Mason Hospital, Seattle, WA 
  • MD, Case Western Reserve School of Medicine, Cleveland, OH, 1970 

Certifications

  • American Board of Surgery

Memberships

  • American Society of Clinical Oncology
  • American College of Surgeons

Honors & Awards

  • Best Doctors in America® 2014
  • Philadelphia Magazine Top Docs, 2009-2014

Linda Snow

Breast Cancer

Linda Snow

Breast Cancer

As soon as Linda Snow learned she was adopted, she was curious about her roots. As a teen, she wondered about the health history of her birth parents. In addition to suggesting she have her first mammogram at age 30 to obtain a baseline, Linda’s OB/GYN referred her to the Risk Assessment Program at Fox Chase Cancer Center founded by Mary Daly, MD, PhD.

Laura Marblestone

Breast Cancer

Laura Marblestone

Breast Cancer

Laura Marblestone's mother was only 43 when she lost her fight with breast cancer. That's why Laura, a registered nurse and resident of Langhorne, PA, regularly performed breast self-exams. In May 1990, at the age of 40, Laura detected lumps in her left breast. Results from a lumpectomy were benign, but around the same time, she developed a lump under her arm, which her doctor said was a swollen lymph gland, likely related to the surgery. "He told me it was nothing, I didn't have to worry."

Baha Malik

Pancreatic Cancer

Baha Malik

Pancreatic Cancer

In 2007 when Baha Malik started experiencing back pain, he ignored it. “You know – that macho thing we do,” said the retired data specialist, who turned 75 in 2013. “Finally it got so excruciating that my wife demanded I go to a hospital. When I did that, a biopsy revealed that I had cancer of the pancreas.  That’s when my primary physician made arrangements for me to go to Fox Chase Cancer Center – which was a real blessing.”

Novella Lyons

Breast Cancer

Novella Lyons

Breast Cancer

Novella Lyons was well aware that women who have immediate relatives with breast cancer are at increased risk of developing the disease themselves. So when her mother died of breast cancer, Novella knew that breast cancer was a real threat.

In 1993, when Novella was diagnosed with breast cancer, she was treated at one of Philadelphia's large city hospitals.

Novella shared these thoughts with a friend who suggested she have her follow-up care with the doctors at Fox Chase Cancer Center.

Barbara Lanza

Pancreatic Cancer

Barbara Lanza

Pancreatic Cancer

In January 2010, Barbara Lanza had just turned 52. Like many women her age, she was trying to lose weight and even tried green tea pills. She began experiencing stomach problems and attributed it to the pills, along with a stressful and physical job working in a dog kennel. Still, she took a family trip to Florida and visited the emergency room four times during her 10 day trip. “I was told it was pancreatitis because my cancer marker levels were too low for concern,” shared Barbara.

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Research Interests

Translational and clinical research in pancreatic cancer. We have several trials here from looking at basic mechanisms of pancreatic cancer growth and genetic structures to trials in sequencing, types of adjuvant therapies and surgical treatments of pancreatic cancer.