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Christina S. Chu, MD

Christina Chu, MD

Clinical Locations

Primary Location

Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111


Interim Chief, Division of Gynecologic Oncology

Professor, Department of Surgical Oncology

Director, Gynecologic Oncology Fellowship Program

NCCN, Cervical/Uterine Cancers Panel Member

Key Awards

Philadelphia Magazine Top Docs 2021
Gynecologic Oncology

Treatment Philosophy

I consider it an honor to be able to care for women with gynecologic cancer. One of the reasons that I chose the field of gynecologic oncology is the unique opportunity I have to help provide both breadth and depth of care for women with cancer and complex benign disease. In my practice, I am able to offer a full range of individualized therapies: State-of-the-art surgery, including minimally invasive techniques, as well as chemotherapy and cutting-edge clinical trials. Through this continuity of care, I find that the relationships that I am able to form with women and their families are among the most rewarding aspects of my life.

I was thrilled to join Fox Chase in 2014 after receiving my training and spending the first 12 years of my career at the University of Pennsylvania.  As an NCI-designated Comprehensive Cancer Center, Fox Chase offers the best in patient-centered care and innovative research.  I believe that we must make progress in the fight against cancer, and I have particular interest in clinical trials for the treatment of ovarian, endometrial and cervical cancers.  I have served as principal investigator of multiple trials of novel agents and my research interests focus on investigational immunotherapies, including tumor vaccination and adoptive immunotherapy for ovarian cancer, as well as therapeutic HPV vaccination.  I also have particular interests in weight loss interventions to modify risk for women with endometrial hyperplasia and endometrial cancer.

I believe in treating patients as if they were my own family.  With the fantastic team in place here at Fox Chase, it is my goal to be able to help patients and their families be surrounded not only by the latest in medical expertise, but also by a community of caring to help support them through difficult times.

Education and Training

Educational Background

  • Fellow, Gynecologic Oncology, Hospital of the University of Pennsylvania, Philadelphia, PA 
  • Resident, Obstetrics and Gynecology, Hospital of the University of Pennsylvania, Philadelphia, PA 
  • MD, University of Pennsylvania School of Medicine, Philadelphia, PA, 1995 


  • The American Board of Obstetrics and Gynecology, Obstetrics and Gynecology, Gynecologic Oncology 


  • National Comprehensive Cancer Network (NCCN)
    • Cervical/Uterine Cancers Panel
  • American Association for Cancer Research
  • NRG Oncology, Gynecologic Oncology Group (Phase I Committee, 2007 to present)
  • American College of Obstetricians
  • Society of Gynecologic Oncologists (Government Relations Committee, 2009 to 2014) (Diversity and Inclusion Task Force, 2017 to present) (Clinical Practice Committee, 2017 to present)
  • Mid-Atlantic Gynecologic Oncologic Society 
  • International Gynecologic Cancer Society
  • American Society of Clinical Oncology

Honors & Awards

  • Philadelphia Magazine Top Doctors, Gynecologic Oncology, 2011-12, 2014-2022
  • America's Top Doctors®2016-17
  • University of Pennsylvania Faculty Teaching Award for Excellence in Resident Education, 2010
  • American College of Obstetricians and Gynecologists Council on Resident Education in Obstetrics and Gynecology National Faculty Award for Excellence in Resident Education, 2010
  • Philadelphia Magazine Top Doctors, Cervical Cancer and Endometrial Cancer, 2010 
Patient Stories

Alexandrea Amerine

Ovarian & Primary Peritoneal Cancer

Alexandrea Amerine

Ovarian & Primary Peritoneal Cancer

I’ve always been a relatively healthy person. I’m 46 years old and have never had any major health concerns. That’s why I wasn’t too worried at first when I noticed a somewhat unusual protrusion from my abdomen. I assumed I had just gained some weight and told myself I needed to get on top of it. It wasn’t until my annual OBGYN appointment that I found out it was much more serious than that.

Patricia Caggiano

Vulvar Cancer

Patricia Caggiano

Vulvar Cancer

I’m 89 years old, and I love my life. I have a wonderful family who I adore. I have two grown children, four granddaughters, and four great-granddaughters—and a fifth great-grandchild on the way! I’m a fabulous cook and baker, and I love to travel.

When I was diagnosed with cancer, it was a total shock. I’d watched my husband of 50 years die of lung cancer, and I saw what he went through. So I was scared.

Christin Repas

Ovarian & Primary Peritoneal Cancer

Christin Repas

Ovarian & Primary Peritoneal Cancer

In 2001 at the age of 18, I was diagnosed with polycystic ovary syndrome (PCOS), which is a hormonal disorder common among women. I handled it over the years with birth control and eventually an IUD, but in 2014 things started to change. My periods became unpredictable. I was feeling different and bleeding much worse than I ever had before. I knew something was going on and during that time, I saw many different OBGYNs, but oftentimes their response was, “You have PCOS, this is the expected.” But I knew my body and I knew this wasn’t normal for me.

Jennifer Nemcik

Ovarian & Primary Peritoneal Cancer

Jennifer Nemcik

Ovarian & Primary Peritoneal Cancer

I work as a nurse in the operating room at Fox Chase Cancer Center, so I know how important it is to get specialized care for a cancer diagnosis. A few years ago, my husband and I had decided to start a family. After some time, nothing was happening and since I was getting close to my mid-thirties, we decided to seek fertility treatment. During a routine ultrasound at my first appointment, they found a cyst about the size of a softball on my ovary.

Carol Desko

Endometrial (Uterine) Cancer

Carol Desko

Endometrial (Uterine) Cancer

"I felt comfortable with Dr. Chu and knew I was in good hands."

Research Profile

Research Interests

Clinical trials for the evaluation of novel chemotherapies and immunotherapies for gynecologic malignancies. 


Selected Publications

Effectiveness and safety of expanded perioperative thromboprophylaxis in complex gynecologic surgery. Corr BR, Winter AM, Sammel MD, Chu CS, Gage BF, Hagemann AR. Gynecol Oncol. 2015 Sep;138(3):501-6. doi: 10.1016/j.ygyno.2015.07.017. Epub 2015 Jul 14.  PMID: 26186912

Clinical predictors of bevacizumab-associated gastrointestinal perforation. Tanyi JL, McCann G, Hagemann AR, Coukos G, Rubin SC, Liao JB, Chu CS. Gynecol Oncol. 2011 Mar;120(3):464-9. doi: 10.1016/j.ygyno.2010.11.009. Epub 2010 Dec 17.
PMID: 21168199

Braly P, Nicodemus CF, Chu C, Collins Y, Edwards R, Gordon A, McGuire W, Schoonmaker C, Whiteside T, Smith LM, Method M. The immune adjuvant properties of front-line carboplatin-paclitaxel: A randomized phase II study of alternative schedules of intravenous oregovomab-chemo-immunotherapy in advanced ovarian cancer. J Immunother 2009; 32:54-65.

Katz E, Dugan NL, Cohn JC, Chu C, Smith RG, Schmitz KH. Weight lifting in patients with lower extremity lymphedema secondary to cancer: A pilot and feasibility study. Arch Phys Med Rehabil 2010; 91:1070-6.
Hagemann AR, Cadungog M, Hagemann IS, Hammond R, Adams SF, Chu, CS, Rubin SC, Zhang L, Addya K, Birrer MJ, Gimmoty PA, Coukos G. Tissue-based immune monitoring I: Tumor core needle biopsies allow in-depth interrogation of the tumor microenvironment. Cancer Biol Ther, 2011; 12(4):357-66.

Hagemann AR, Hagemann IS, Cadungog M, Hwang WT, Patel P, Lal P, Hammond R, Gimotty PA, Chu CS, Rubin SC, Coukos G. Tissue-based immune monitoring II: Multiple tumor sites reveal immunologic homogeneity in serous ovarian carcinoma. Cancer Biol Ther 2011; 12(4):367-77.

Chu CS, Boyer J, Schullery DS, Gimotty PA, Gamerman V, Bender J, Levine BL, Coukos G, Rubin SC, Morgan MA, Vonderheide RH, June CH. Phase I/II randomized trial of dendritic cell vaccination with or without cyclophosphasmide for consolidation therapy of advanced ovarian cancer in first or second remission. Cancer Immunol Immunother 2012; 61(5):629-641.

Bahng AY, Chu CS, Wileyto P, Rubin SC, Lin LL. Risk factors for recurrence amongst high intermediate risk patients with endometrioid adenocarcinoma. J Gynecol Oncol 2012; 23(4):257-64.

Brown JC, Cheville A, Chu CS, Schmitz KH. The prevalence of lymphedema symptoms among long-term cancer survivors with or at-risk for lower limb lymphedema. Am J Phys Med Rehab 2013; 92(3):223-31.

Chu CS, Boyer JD, Jawad A, McDonald K, Rogers WT, Prak ETL, Sullivan KE. Immunologic consequences of chemotherapy for ovarian cancer: Impaired responses to the influenza vaccine. Vaccine 2013; 31:5435-42.

Brown JC, John GM, Segal S, Chu CS, Schmitz KH. Physical activity and lower limb lymphedema among uterine cancer survivors. Med Sci Sports Exerc 2013; 45:2091-7.

Anwer K, Kelly FJ, Chu C, Jewell JG, Lewis D, Alvarez RD. Phase I trial of a formulated IL-12 plasmid in combination with carboplatin and docetaxel chemotherapy in the treatment of platinum-sensitive recurrent ovarian cancer. Gynecol Oncol 2013; 131:169-73.

Simpkins F, Flores A, Chu C, Berek JS, Lucci III J, Murray S, Bauman J, Struemper H, Germaschewski F, Jonak Z, Gardner O, Toso J, Coukos G. Chemoimmunotherapy using pegylated liposomal Doxorubicin and interleukin-18 in recurrent ovarian cancer: a phase I dose-escalation study. Cancer Immunol Res 2013; 1:168-78.

Hammer SM, Brown JC, Segal S, Chu CS, Schmitz K. Cancer-related impairments influence physical activity in uterine cancer survivors. Med Sci Sports Exerc. 2014 Dec;46(12):2195-201.

Brown JC, Lin LL, Segal S, Chu CS, Haggerty AE, Ko EM, Schmitz KH. Physical activity, daily walking, and lower limb lymphedema associate with physical function among uterine cancer survivors. Support Care Cancer. 2014 Nov;22(11):2017-25.

Additional Publications

Dr. Chu on PubMed

Dr. Chu on Publons



Our Patient Satisfaction Rating is an average of all responses to care provider related questions from our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more.


4.7 / 5.0


  • 4.8
  • 4.7
  • 4.8
  • 4.8
  • 4.6


  • 5.0
    June 22, 2022
    Love *Dr. Chu & her team, always so informative & kind.
  • 4.0
    June 08, 2022
    Dr Chu is an awesome surgeon, and her staff was excellent.
  • 5.0
    May 13, 2022
    Very friendly
  • 5.0
    April 15, 2022
    I felt assured that Fox Chase was and is with me the whole way to fight cancer. Have much respect for Dr. Chu. Thank you. XO
  • 5.0
    March 28, 2022
    My visits with Dr Chu are always good!
  • 5.0
    March 18, 2022
    Everyone on my treatment team is outstanding and caring very professional.
  • 4.5
    February 25, 2022
    I have received the BEST care from all of [...] - Dr. Chu is exceptional -
  • 5.0
    January 31, 2022
    Coming to see Dr. Chu is always a pleasant experience. I know I am in very good hands.
  • 5.0
    December 15, 2021
    Dr. Chu was very kind, helpful, and explained everything clearly.
  • 5.0
    December 11, 2021
    My experience was very warm, welcoming and friendly
  • 5.0
    December 10, 2021
    Excellent visit experience.
  • 5.0
    December 09, 2021
    Dr Chu is the only doctor I ever had who phoned another doctor in another practice to express concern about a health issue that came up unrelated to the reason I was seeing Dr Chu. I appreciated that very much.
  • 5.0
    November 29, 2021
    My experience with Dr. Chu and Fox Chase was excellent.
  • 5.0
    October 23, 2021
    I have been seeing and treated by Dr Christina Chu and her team since 2018 and feel very confident In Their care. She is always very thorough and caring. We have formed a bond dr chu and [...] are the best. I feel like I am being taken care of. They are concerned about my health as well as my personal life and family. I love them!
  • 5.0
    October 22, 2021
    Dr Chu snd her staff are wonderful!!
  • 5.0
    October 18, 2021
    Very good experience.
  • 5.0
    October 08, 2021
    Dr CHU is amazing and attentive. Nothing is a problem and no question is not important. Honestly she saved my life and I am forever great full.
  • 5.0
    September 24, 2021
    Dr Chu is the best ever!! Great staff also!!
  • 5.0
    September 24, 2021
    Dr Chu is one of the best in the city! Thankful to have her !
  • 5.0
    September 02, 2021
    Giving honest answers to all my questions and concerns about my condition

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