Christina S. Chu, MD

Christina Chu, MD

Clinical Locations

Primary Location

Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111


Professor, Department of Surgical Oncology

Ovarian and Gynecologic Cancer TRDG Member

Director, Gynecologic Oncology Fellowship Program

NCCN, Cervical/Uterine Cancers Panel Member

Key Awards

Philadelphia Magazine Top Docs 2020
   Gynecologic Oncology

Treatment Philosophy

I consider it an honor to be able to care for women with gynecologic cancer. One of the reasons that I chose the field of gynecologic oncology is the unique opportunity I have to help provide both breadth and depth of care for women with cancer and complex benign disease. In my practice, I am able to offer a full range of individualized therapies: State-of-the-art surgery, including minimally invasive techniques, as well as chemotherapy and cutting-edge clinical trials. Through this continuity of care, I find that the relationships that I am able to form with women and their families are among the most rewarding aspects of my life.

I was thrilled to join Fox Chase in 2014 after receiving my training and spending the first 12 years of my career at the University of Pennsylvania.  As an NCI-designated Comprehensive Cancer Center, Fox Chase offers the best in patient-centered care and innovative research.  I believe that we must make progress in the fight against cancer, and I have particular interest in clinical trials for the treatment of ovarian, endometrial and cervical cancers.  I have served as principal investigator of multiple trials of novel agents and my research interests focus on investigational immunotherapies, including tumor vaccination and adoptive immunotherapy for ovarian cancer, as well as therapeutic HPV vaccination.  I also have particular interests in weight loss interventions to modify risk for women with endometrial hyperplasia and endometrial cancer.

I believe in treating patients as if they were my own family.  With the fantastic team in place here at Fox Chase, it is my goal to be able to help patients and their families be surrounded not only by the latest in medical expertise, but also by a community of caring to help support them through difficult times.

Education and Training

Educational Background

  • Fellow, Gynecologic Oncology, Hospital of the University of Pennsylvania, Philadelphia, PA 
  • Resident, Obstetrics and Gynecology, Hospital of the University of Pennsylvania, Philadelphia, PA 
  • MD, University of Pennsylvania School of Medicine, Philadelphia, PA, 1995 


  • The American Board of Obstetrics and Gynecology, Obstetrics and Gynecology, Gynecologic Oncology 


  • National Comprehensive Cancer Network (NCCN)
    • Cervical/Uterine Cancers Panel
  • American Association for Cancer Research
  • NRG Oncology, Gynecologic Oncology Group (Phase I Committee, 2007 to present)
  • American College of Obstetricians
  • Society of Gynecologic Oncologists (Government Relations Committee, 2009 to 2014) (Diversity and Inclusion Task Force, 2017 to present) (Clinical Practice Committee, 2017 to present)
  • Mid-Atlantic Gynecologic Oncologic Society 
  • International Gynecologic Cancer Society
  • American Society of Clinical Oncology

Honors & Awards

  • Philadelphia Magazine Top Doctors, Gynecologic Oncology, 2011-12, 2014-20
  • America's Top Doctors®2016-17
  • University of Pennsylvania Faculty Teaching Award for Excellence in Resident Education, 2010
  • American College of Obstetricians and Gynecologists Council on Resident Education in Obstetrics and Gynecology National Faculty Award for Excellence in Resident Education, 2010
  • Philadelphia Magazine Top Doctors, Cervical Cancer and Endometrial Cancer, 2010 
Patient Stories

Carol Desko

Endometrial (Uterine) Cancer

Carol Desko

Endometrial (Uterine) Cancer

"I felt comfortable with Dr. Chu and knew I was in good hands."

Research Profile

Research Interests

Clinical trials for the evaluation of novel chemotherapies and immunotherapies for gynecologic malignancies. 


Selected Publications

Effectiveness and safety of expanded perioperative thromboprophylaxis in complex gynecologic surgery. Corr BR, Winter AM, Sammel MD, Chu CS, Gage BF, Hagemann AR. Gynecol Oncol. 2015 Sep;138(3):501-6. doi: 10.1016/j.ygyno.2015.07.017. Epub 2015 Jul 14.  PMID: 26186912

Clinical predictors of bevacizumab-associated gastrointestinal perforation. Tanyi JL, McCann G, Hagemann AR, Coukos G, Rubin SC, Liao JB, Chu CS. Gynecol Oncol. 2011 Mar;120(3):464-9. doi: 10.1016/j.ygyno.2010.11.009. Epub 2010 Dec 17.
PMID: 21168199

Braly P, Nicodemus CF, Chu C, Collins Y, Edwards R, Gordon A, McGuire W, Schoonmaker C, Whiteside T, Smith LM, Method M. The immune adjuvant properties of front-line carboplatin-paclitaxel: A randomized phase II study of alternative schedules of intravenous oregovomab-chemo-immunotherapy in advanced ovarian cancer. J Immunother 2009; 32:54-65.

Katz E, Dugan NL, Cohn JC, Chu C, Smith RG, Schmitz KH. Weight lifting in patients with lower extremity lymphedema secondary to cancer: A pilot and feasibility study. Arch Phys Med Rehabil 2010; 91:1070-6.
Hagemann AR, Cadungog M, Hagemann IS, Hammond R, Adams SF, Chu, CS, Rubin SC, Zhang L, Addya K, Birrer MJ, Gimmoty PA, Coukos G. Tissue-based immune monitoring I: Tumor core needle biopsies allow in-depth interrogation of the tumor microenvironment. Cancer Biol Ther, 2011; 12(4):357-66.

Hagemann AR, Hagemann IS, Cadungog M, Hwang WT, Patel P, Lal P, Hammond R, Gimotty PA, Chu CS, Rubin SC, Coukos G. Tissue-based immune monitoring II: Multiple tumor sites reveal immunologic homogeneity in serous ovarian carcinoma. Cancer Biol Ther 2011; 12(4):367-77.

Chu CS, Boyer J, Schullery DS, Gimotty PA, Gamerman V, Bender J, Levine BL, Coukos G, Rubin SC, Morgan MA, Vonderheide RH, June CH. Phase I/II randomized trial of dendritic cell vaccination with or without cyclophosphasmide for consolidation therapy of advanced ovarian cancer in first or second remission. Cancer Immunol Immunother 2012; 61(5):629-641.

Bahng AY, Chu CS, Wileyto P, Rubin SC, Lin LL. Risk factors for recurrence amongst high intermediate risk patients with endometrioid adenocarcinoma. J Gynecol Oncol 2012; 23(4):257-64.

Brown JC, Cheville A, Chu CS, Schmitz KH. The prevalence of lymphedema symptoms among long-term cancer survivors with or at-risk for lower limb lymphedema. Am J Phys Med Rehab 2013; 92(3):223-31.

Chu CS, Boyer JD, Jawad A, McDonald K, Rogers WT, Prak ETL, Sullivan KE. Immunologic consequences of chemotherapy for ovarian cancer: Impaired responses to the influenza vaccine. Vaccine 2013; 31:5435-42.

Brown JC, John GM, Segal S, Chu CS, Schmitz KH. Physical activity and lower limb lymphedema among uterine cancer survivors. Med Sci Sports Exerc 2013; 45:2091-7.

Anwer K, Kelly FJ, Chu C, Jewell JG, Lewis D, Alvarez RD. Phase I trial of a formulated IL-12 plasmid in combination with carboplatin and docetaxel chemotherapy in the treatment of platinum-sensitive recurrent ovarian cancer. Gynecol Oncol 2013; 131:169-73.

Simpkins F, Flores A, Chu C, Berek JS, Lucci III J, Murray S, Bauman J, Struemper H, Germaschewski F, Jonak Z, Gardner O, Toso J, Coukos G. Chemoimmunotherapy using pegylated liposomal Doxorubicin and interleukin-18 in recurrent ovarian cancer: a phase I dose-escalation study. Cancer Immunol Res 2013; 1:168-78.

Hammer SM, Brown JC, Segal S, Chu CS, Schmitz K. Cancer-related impairments influence physical activity in uterine cancer survivors. Med Sci Sports Exerc. 2014 Dec;46(12):2195-201.

Brown JC, Lin LL, Segal S, Chu CS, Haggerty AE, Ko EM, Schmitz KH. Physical activity, daily walking, and lower limb lymphedema associate with physical function among uterine cancer survivors. Support Care Cancer. 2014 Nov;22(11):2017-25.

Additional Publications

Dr. Chu on PubMed

Dr. Chu on Publons



Our Patient Satisfaction Rating is an average of all responses to care provider related questions from our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more.


4.7 / 5.0


  • 4.8
  • 4.8
  • 4.8
  • 4.8
  • 4.5


  • 5.0
    July 31, 2020
    Dr. Chu is always friendly & positively upbeat!!
  • 5.0
    July 31, 2020
  • 5.0
    July 04, 2020
    Dr. Chu is brilliant as a doctor and surgeon and effective as a communicator. I have already recommended her to many people and I will continue to do so whenever a chance comes up. She is simply the best.
  • 5.0
    June 25, 2020
    Dr. Chu is the best!!!
  • No Star Ratings Available June 19, 2020
    Dr. Chu and her team are excellent. She is my GYN doctor, because of a genetic condition. She is very attentive to even the slightest changes. I feel safe in her hands.
  • 5.0
    June 03, 2020
    [...] Dr. Chu is competent; empathetic and listened to my concern; I look forward to getting to know her better as my treatment goes on.
  • 5.0
    April 26, 2020
    My office visit was cancelled due to COVID-19 so Dr. Chu conducted a telehealth visit, with which I was very satisfied. My office visit was rescheduled.
  • 5.0
    April 23, 2020
    Great doctor and staff. They worked very well together as a team.
  • 5.0
    April 23, 2020
    very good
  • 5.0
    April 10, 2020
    I always felt cared about and listened to.
  • 5.0
    March 18, 2020
  • 5.0
    February 22, 2020
    Dr. Chu and her staff have been extremely attentive. [...]
  • 5.0
    February 13, 2020
    Dr Chu is amazing I owe my life to her for the medical care she has provided me. I followed her [...] to Fox Chase because of the amazing care she has taken of me for 10 years now !!
  • 5.0
    February 12, 2020
    After coming to Fox Chase to get a second opinion for cancer treament, I'm very pleased with my care that Fox Chase has provded thus far. Every staff memeber including Dr Christina Chu have been very thorough. I feel very confident about my OVER-ALL care.
  • 4.5
    January 24, 2020
    Dr. Chu is an excellent doctor. I have recommended her to someone who is now her patient.
  • 5.0
    December 11, 2019
    Good experience.
  • 5.0
    December 02, 2019
  • 5.0
    November 07, 2019
    Dr. Chu is an awesome doctor!! she saved my life. [...]
  • 5.0
    October 07, 2019
    Love Dr. Chu. She basically saved my life 4 1/2 yrs. ago and your Cancer Center.
  • 5.0
    September 29, 2019
    Excellent, excellent, excellent. Dr. Chu is the best provider I could ask for!

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