Andreas Karachristos, MD, PhD, FACS
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Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111
Director, Hepatic Surgery
Associate Professor of Clinical Surgery
NCCN, Hepatobiliary Cancers Panel Member
- Specializing in the treatment of
- benign and malignant tumors of the liver with a special interest in complex tumors requiring vascular reconstruction
- gallbladder and biliary tumors
- pancreatic cancer; neuroendocrine tumors of the pancreas; chronic pancreatitis
- vena cava tumors and cancers involving the vena cava
- Use of veno-veno bypass and in situ perfusion for massive liver tumors
- Resection of primary liver cancers (Hepatocellular Carcinoma) and metastatic cancers to the liver
- Open and minimally invasive (laparoscopic and robotic) surgery for liver tumors
- Open and minimally invasive (laparoscopic and robotic) surgery for pancreatic cancer
- Surgery for chronic pancreatitis
- Complex biliary reconstruction after bile duct injury
- Complex venous and arterial reconstruction for liver and pancreatic tumors
Language(s) Other than English
As Head of Liver Surgery at Fox Chase Cancer Center, I oversee the Liver Tumor Services. I have extensive experience in the surgical treatment involving cancer of the liver, bile ducts and pancreas. I have performed more than 300 liver resections. I am particularly interested in tumors that are not considered resectable by traditional criteria. I work closely with extremely talented members of the Medical Oncology and Radiation Oncology teams, providing the best of multidisciplinary treatments. At Fox Chase, we have multiple tumor boards where experts in different specialties meet weekly to discuss complex patients. We participate in innovative clinical trials offering our patients traditional and out of box therapy options.
The diagnosis of cancer and the multiple treatment options existing in our current armamentarium can be confusing and exhausting to the already anxious patient. I take time to explain step by step all available treatment modalities and help the patient choose the best treatment plan that fits the patient’s particular needs. For patients in whom surgery is the best option, I pay attention to explain the procedure in a manner understandable to the non-expert. I firmly believe that the inability to explain your expertise to anyone means lack of it. Furthermore, I make myself easily available for questions and all my patients have my cell phone.
Modern technology offers treatment options for cancer patients that were unimaginable only few years ago. However, I believe in the correct use of medical innovations towards the patient’s benefit and apply the “no harm” dictum first.
Follow on Twitter: @FCCCSurgOnc
- Fellow (ASTS), Abdominal Organ Transplantation and Hepatobiliary Surgery, University of Cincinnati, Cincinnati, OH, 2007
- Resident, General Surgery, Temple University Hospital, Philadelphia, PA, 2005
- Resident, General Surgery, Yale New Haven Hospital, New Haven, CT, 2002
- MD, Medical School, University of Crete, 1992
- American Board of Surgery
Honors & Awards
- Diamond Award, Temple University Hospital Abdominal Organ Transplant Program, 2009
In 2013, Melissa Kartasevich was enjoying life, raising her six year old daughter, Sarah and engaged to be married to her fiancé, Dennis Dupre. In April, she woke one morning with pain and discomfort on her left side. Assuming it was a result of sleeping in a bad position, she took pain medication and went to work. By lunch time, the pain worsened so Melissa went to the emergency room. The doctors ran some tests and performed a CAT scan, where they noticed her spleen had infracted, but didn't know the cause. Melissa was admitted to the hospital for five days, where she underwent further tests revealing a suspicious spot on her pancreas. Next, she had an endoscopic ultrasound (EUS) which confirmed the diagnosis. Melissa, 38, had pancreatic cancer. To say she was shocked would be an understatement.
Debbie Getz is a fighter, there’s no doubting that. After beating inflammatory breast cancer in 1998, she continued diligently with follow-up oncology appointments. “Whenever something questionable showed up on an MRI or CAT Scan, I looked into it immediately,” Debbie recalls.
In March 2014, she experienced pain in her right side. “I thought it was a gall bladder attack,” admits Debbie, who quickly scheduled an appointment with her primary doctor, who sent her for imaging tests.
As a school nurse, Carol Hobson knew the importance of taking care of her own health.
After 23 years in the field, Carol retired in January 2011 at the age of 67. In June, while experiencing severe left shoulder pain, Carol’s husband, Wayne, took her to the emergency room at their local hospital. Doctors performed several tests which were inconclusive. Carol was sent home to follow up with her family doctor.
When he thinks back on October 28, 2013, Jim Tetzlaff realizes it would have been easy to ignore what happened and not give it another thought. “I’m a man – we have a tendency to ignore things that have to do with our health,” says Jim, who was 75 at the time. On that day, after one of his grandson’s football games, Jim went to the bathroom and saw blood in his urine. “It was upsetting, but I didn’t have any other symptoms so I thought it had to be a fluke,” recalls the former medical equipment salesman.
In February, 2014, Robert Sklar believed that he was “indestructible.” At 70, he had never had any serious illnesses, was rarely sick and did not take any medications. But, when he returned from Las Vegas feeling exhausted and not himself, Robert made an appointment with his family doctor. She ordered blood work and conducted a general physical. “My hemoglobin count was 6 and should have been 12. She referred me to my local community hospital for my first ever colonoscopy,” he recalls.
- Basic research: I have extensive laboratory experience studying p53 and microsatellite instability in relation to Hepatitis viruses in Hepatocellular Carcinoma (HCC).
- Clinical Research: I am interested in the enhancement of liver recovery after extensive resection with antioxidant agents and agent modulating portal vein pressure. I am also interested in outcomes research after liver surgery.