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Andreas Karachristos, MD, PhD, FACS

Andreas Karachristos, MD, PhD, FACS

Clinical Locations

Primary Location

Fox Chase Cancer Center
333 Cottman Avenue
Philadelphia, PA 19111

About

Director, Hepatic Surgery

Attending Surgeon, Department of Surgical Oncology

Esophagus, Pancreas, and Liver Cancer TRDG Member

Professor, Clinical Surgery, Lewis Katz School of Medicine, Temple University

NCCN, Hepatobiliary Cancers Panel Member

Treatment Focus

  • Specializing in the treatment of 
    • benign and malignant tumors of the liver with a special interest in complex tumors requiring vascular reconstruction
    • gallbladder and biliary tumors
    • pancreatic cancer; neuroendocrine tumors of the pancreas; chronic pancreatitis
    • vena cava tumors and cancers involving the vena cava
  • Use of veno-veno bypass and in situ perfusion for massive liver tumors
  • Resection of primary liver cancers (Hepatocellular Carcinoma) and metastatic cancers to the liver
  • Open and minimally invasive (laparoscopic and robotic) surgery for liver tumors
  • Open and minimally invasive (laparoscopic and robotic) surgery for pancreatic cancer
  • Surgery for chronic pancreatitis
  • Complex biliary reconstruction after bile duct injury
  • Complex venous and arterial reconstruction for liver and pancreatic tumors

Key Awards

Philadelphia Magazine Top Docs 2018
      Surgery

Language(s) Other than English

Greek

Treatment Philosophy

As Head of Liver Surgery at Fox Chase Cancer Center, I oversee the Liver Tumor Services. I have extensive experience in the surgical treatment involving cancer of the liver, bile ducts and pancreas. I have performed more than 300 liver resections. I am particularly interested in tumors that are not considered resectable by traditional criteria. I work closely with extremely talented members of the Medical Oncology and Radiation Oncology teams, providing the best of multidisciplinary treatments. At Fox Chase, we have multiple tumor boards where experts in different specialties meet weekly to discuss complex patients. We participate in innovative clinical trials offering our patients traditional and out of box therapy options.

The diagnosis of cancer and the multiple treatment options existing in our current armamentarium can be confusing and exhausting to the already anxious patient. I take time to explain step by step all available treatment modalities and help the patient choose the best treatment plan that fits the patient’s particular needs. For patients in whom surgery is the best option, I pay attention to explain the procedure in a manner understandable to the non-expert. I firmly believe that the inability to explain your expertise to anyone means lack of it. Furthermore, I make myself easily available for questions and all my patients have my cell phone.

Modern technology offers treatment options for cancer patients that were unimaginable only few years ago. However, I believe in the correct use of medical innovations towards the patient’s benefit and apply the “no harm” dictum first.

Follow on Twitter: @FCCCSurgOnc

Education and Training

Educational Background

  • Fellow (ASTS), Abdominal Organ Transplantation and Hepatobiliary Surgery, University of Cincinnati, Cincinnati, OH, 2007
  • Resident, General Surgery, Temple University Hospital, Philadelphia, PA, 2005
  • Resident, General Surgery, Yale New Haven Hospital, New Haven, CT, 2002
  • MD, Medical School, University of Crete, 1992

Certifications

  • American Board of Surgery

Honors & Awards

  • Philadelphia Magazine Top Doctors, 2018
  • America's Top Doctors®2016-17
  • Diamond Award, Temple University Hospital Abdominal Organ Transplant Program, 2009
Patient Stories

Barry Taitelman

Kidney Cancer

Barry Taitelman

Kidney Cancer

Becoming a grandfather was something I had been looking forward to for years. But just before I learned that my daughter-in-law was pregnant, I was diagnosed with Stage 4 kidney cancer. Instead of the overwhelming joy I had been anticipating, I was wracked with fear. I couldn’t bear the thought of getting to know my grandson and then not getting to be there to watch him grow up.

Darnell Hutchinson

Liver, Gall Bladder & Bile Duct Cancer

Darnell Hutchinson

Liver, Gall Bladder & Bile Duct Cancer

After being diagnosed with liver cancer, Darnell Hutchinson sought treatment at Fox Chase Cancer Center. Darnell underwent a successful surgical procedure in July of 2016 and was shocked when he did not even need the pain medication he was prescribed. Today he is cancer free and back to work. "People constantly ask me how I wasn’t scared for my life, but I knew with Fox Chase, there was no reason to be. Everyone, from the receptionist, to the doctors and their team, were warm and comforting. I felt right at home."

Debra Getz

Kidney Cancer

Debra Getz

Kidney Cancer

Debbie Getz is a fighter, there’s no doubting that. After beating inflammatory breast cancer in 1998, she continued diligently with follow-up oncology appointments. “Whenever something questionable showed up on an MRI or CAT Scan, I looked into it immediately,” Debbie recalls.

In March 2014, she experienced pain in her right side. “I thought it was a gall bladder attack,” admits Debbie, who quickly scheduled an appointment with her primary doctor, who sent her for imaging tests.

Barbara Lanza

Pancreatic Cancer

Barbara Lanza

Pancreatic Cancer

In January 2010, Barbara Lanza, who had just turned 52, was admitted to the emergency room four times during a trip to Florida. When she returned home, Barabara met with her doctor, where more tests were ordered; the tests revealed a mass on the head of her pancreas. Barbara's doctor referred her to Fox Chase Cancer Center, where she was diagnosed with a rare form of pancreatic cancer. She underwent chemotherapy and radiation before she was ready for a complex surgery, followed by one last procedure: a stent put into her collapsed superior mesenteric vein. Barbara has recovered well and is so pleased she received treatment at Fox Chase. “I had the best team–Dr. Denlinger, Dr. Karachristos, and Dr. Hayes did everything they could to save me. And Dr. Hoffman? What can I say? He’s not head of pancreatic surgery for nothing! He’s the best there is,” she said.

Carol Hobson

Liver, Gall Bladder & Bile Duct Cancer

Carol Hobson

Liver, Gall Bladder & Bile Duct Cancer

After a doctor suspected she had bile duct cancer, Carol Hobson sought the help of specialists at Fox Chase Cancer Center, where a diagnosis of bile duct cancer was finally confirmed after extensive testing. In 2011, she underwent a bile duct resection, followed by chemotherapy and radiation therapy. The treatment was successul, and today Carol has extensive CAT scans and blood work done every three months to check for a possible recurrence. "I can tell you that if you decide to go to Fox Chase, you will get the most knowledgeable people taking care of you. Just as important, you will become part of the Fox Chase family and will be treated like a family member," she said. "That is one of the most outstanding features of Fox Chase Cancer Center."

Pages

Research Profile

Research Interests

  • Basic research: I have extensive laboratory experience studying p53 and microsatellite instability in relation to Hepatitis viruses in Hepatocellular Carcinoma (HCC).
  • Clinical Research: I am interested in the enhancement of liver recovery after extensive resection with antioxidant agents and agent modulating portal vein pressure. I am also interested in outcomes research after liver surgery.
Publications

Selected Publications

Ratings

56 PATIENT SATISFACTION REVIEWS

Our Patient Satisfaction Rating is an average of all responses to care provider related questions from our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more.

OVERALL RATING

4.7 / 5.0

RATINGS BREAKDOWN

  • 4.7
  • 4.6
  • 4.8
  • 4.9
  • 4.6

4 PATIENT COMMENTS

  • 5.0
    September 24, 2018
    Very gracious, even though he was not feeling 100%.
  • 5.0
    June 28, 2018
    my daughter-in-law brings me to my appointments so she can hear what the doctor says. every doctor and nurse is very patient with us, answering every question and explaining each answer for both of us.
  • 4.5
    June 23, 2018
    Dr. Karachristos is kind & gentle with his delivery about issues, the best.
  • 5.0
    February 13, 2018
    All my providers of care have been excellent.
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