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Technology Transfer Licensing (available technologies for licensing)

Available technologies for licensing and/or research collaborations

Animal Models 

  • Appl1 Knockout Mouse
  • MISIIR-TAg Mouse - A New Model of Epithelial Ovarian Cancer
  • TetOp16 Transgenic Mouse Model for Cancer and Cell Proliferation Research
  • Apc+/Min-FCCC Mouse: a Model for Colorectal Cancer

Diagnostics -  Cancer

  • Diagnostic Method for Early Pancreatic Cancer Detection
  • Markers for Early Diagnosis of Cancer
  • Markers for Renal Cancer Diagnosis and Prognosis

Medical Devices

  • Endoscope Handle Manipulator
  • The Easy Attach
  • Easy Positioning Belt
  • Scent-releasing Respiratory Mask

Research Materials

Vectors
  • PGLS20 vector: A novel dual purpose vector for protein expression in E.coli and S.cerevisiae
  • A Mutated Human Cytomegalovirus Expression Vector With Enhanced Ability to Express Foreign Genes
  • A Chimeric Integrase-Containing Expression Vector for Promoting Targeted Integration of Foreign DNA into a Host Genome
Polyclonal Antibodies
  • Polyclonal Antibodies: FAP, phospho-PIX
  • Polyclonal Antibodies: HEPL, ATM
Monoclonal Antibodies
  • Monoclonal Antibodies: ASF1a, HEF1/NEDD9/Cas-L, hBUBs
  • Monoclonal Antibodies: CENP-E
  • Monoclonal Antibodies: Mad1, Mad2, HIRA
Endonucleases
  • MED1 Glycosylase, a Tool for Detection of transition SNPs at CpG sites (CT-SNPs)
Cell Lines
  • Murine and Human Non-Hepatic Cell Lines that support Hepatitis C Virus replication
  • Scid.adh, A Thymic Cell Line That Mimics T-Cell Development In Vitro
  • HEF1/Cas-L, A Novel Signal Transduction Molecule Associated with Cell Motility, Growth, Apoptosis and Oncogenic Transformation

Research Methods, Screens and Assays

  • Advanced Method for Generating Gene- or Pathway-Targeted Functional Probe Set
  • ELISA Assay for the Detection of Ectromelia and Vaccinia Virus Antibodies in Mice, using Recombinant Viral Proteins
  • The Two Hybrid Dual Bait System: An Improved Two Hybrid System for the Detection of Protein-Protein Interactions
  • A Yeast Bioassay System for the Identification of Compounds That Can Lower Plasma Homocysteine Levels
  • P53-Dependent Asymmetric Cell Division - A Novel Screen for Growth Regulatory Compounds
  • Methods of Screening for Inhibitors of Autoinhibited Proteins
  • A Novel Tumor Cell Marker for use in Evaluating Cancer Therapeutics
  • Cenp-F, A Novel Cell-Cycle Specific Protein That Is Involved in Chromosomal Segregation During Mitosis

Software

  • Array Explorer™ — Image-Processing Software for cDNA Microarray Analysis

Therapeutics

Cancer Therapeutics and Discovery Targets
  • Combination Therapy for the Treatment of Cancer
  • HEF1/Cas-L, A Novel Signal Transduction Molecule Associated with Cell Motility, Growth, Apoptosis and Oncogenic Transformation
  • Human BUB Genes: Mitotic Checkpoint Kinases
  • Identification of Putative Interacting Components in Complex Pathways
  • MED1 (MBD4), A Novel Gene Associated with Cancer Drug Resistance
  • Method for the Treatment or Prophylaxis of LAM
  • Novel Methods for Inhibiting Angiogenesis
  • Nucleic Acid Cleavage Assay for Transposase/Integrase Protein Superfamily
  • OVCA1 and OVCA2 Tumor Suppressor Genes
  • P53-Dependent Asymmetric Cell Division - A Novel Screen for Growth Regulatory Compounds
  • Pregnancy-Associated Genetic Signatures in the Human Breast
  • Rational Antibody Design
  • Synergistic Cytotoxic Effect of Combined Nucleoside/Base Analogs
  • Target Therapy for Ovarian Cancer
  • Tumor-Specific Antisense Therapy to Inhibit Bcl-2 Expression and Induce Apoptosis for Treatment of Non-Hodgkin's Lymphoma
  • MRP-Related Transporter Genes Involved in Erectile Dysfunction Signaling Pathway, Drug Resistance and Connective Tissue Homeostasis
Proton Beam Radiotherapy
  • Building an Enormous Cancer Killer
Therapeutic Antibodies
  • Rational Antibody Design
Antibiotics, Industrial Chemicals and Herbicides
  • A Novel Specific Inhibitor of Tetrapyrrole Biosynthesis in Plants
  • Porphobilinogen Synthase: A Novel Specific Inhibitor of Tetrapyrrole Biosynthesis in Plants
HIV/AIDS
  • ATR Kinase – A Novel Target for Anti-Retroviral Drug Discover
Urology
  • MRP-Related Transporter Genes Involved in Erectile Dysfunction Signaling Pathway, Drug Resistance and Connective Tissue Homeostasis

Vaccines

  • Use of secreted/cell-bound poxvirus proteins (SPVP) and use thereof as vaccines and antiviral agents - Dr. Luis Sigal, DVM, PhD