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Original Research

• Lewis JS, Meeke K, Osipo C, Ross EA, Kidawi N, Li T, Bell E, Chandel NS, Jordan VC. Intrinsic mechanism of estradiol-induced apoptosis in breast cancer cells resistant to estrogen deprivation. J Natl Cancer Inst. 2005; 97:1746-59. PubMed
• Lewis JS, Vijayanathan V, Thomas TJ, Pestell RG, Albanese C, Gallo MA, and Thomas T. Phosphorylation of ATF-2 and Cyclin D1 Activation by estradiol and spermine in MCF-7 breast cancer cells: A mechanism involving the p38 MAP kinase. Oncol Res. PubMed
2005;15:113-28.
• Lewis JS, Thomas TJ, Pestell RG, Albanese C, Gallo MA, and Thomas T. Differential effects of 16α-hydroxyestrone and 2-methoxyestradiol on cyclin D1 involving the transcription factor ATF-2 in MCF-7 cells. J Mol Endo. 2005;34:91-105. PubMed
• Lewis JS, Osipo C, Meeke K, Jordan VC. Estrogen induces apoptosis in a breast cancer model resistant to aromatase inhibitors. J Steroid Biochem. Mol Biol. 2005;94:131-41.
• Lewis JS, Thomas TJ, Klinge CM, Gallo MA, Thomas T. Regulation of cell cycle and cyclins by 16alpha-hydroxyestrone in MCF-7 breast cancer cells. J Mol Endocrinol. 2001;27:293-307. PubMed
• Shah N, Thomas TJ, Lewis JS, Klinge CM, Shirahata A, Gelinas C, Thomas T. Regulation of estrogenic and nuclear factor kappa B functions by polyamines and their role in polyamine analog-induced apoptosis of breast cancer cells. Oncogene. 2001;20:1715-29. PubMed
• Lewis JS, Thomas TJ, Shirahata A, Thomas T. Self-assembly of an oligodeoxyribonucleotide harboring the estrogen response element in the presence of polyamines: ionic, structural, and DNA sequence specificity effects. Biomacromolecules. 2000;1:339-49. PubMed
• Thomas T, Kulkarni GD, Gallo MA, Greenfield N, Lewis JS, Shirahata A, Thomas TJ. Effects of natural and synthetic polyamines on the conformation of an oligodeoxyribonucleotide with the estrogen response element. Nucleic Acids Res. 1997;25:2396-402. PubMed

Book Chapters and Reviews

• Maximov PY, Lewis-Wambi JS, Jordan VC. The paradox of oestradiol-induced breast cancer cell growth and apoptosis. Curr Signal Transduction Ther. 2009;4:88-102. PubMed
• Lewis-Wambi JS, Jordan VC. Estrogen regulation of apoptosis: how can one hormone stimulate and inhibit? Breast Cancer Res. 2009;11:206. PubMed
• Jordan VC, Patel R, Lewis-Wambi JS, Swaby RF. By looking back we can see the way forward: enhancing the gains achieved with antihormone therapy. Breast Cancer Research 2008;10:S16. PubMed
• Jordan VC, Lewis-Wambi JS, Kim H, Cunliffe H, Ariazi E, Sharma C, Shupp HA, Swaby R: Exploiting the apoptotic actions of oestrogen to reverse antihormonal drug resistance in oestrogen receptor positive breast cancer patients. Breast. 2007;16:S105-13. PubMed
• Jordan VC, Ariazi EA, Lewis-Wambi JS, Swaby RR, Cunliffe HR, Riegel AT, Wellstein A. Oestrogen is bad for patients with breast cancer? Breast Cancer Res. 2007;9:S22.
• Ariazi EA, Lewis-Wambi JS, Gill SD, Pyle JR, Ariazi JL, Kim HR, Sharma CGN, Cordera F, Shupp HA, Li T, Jordan VC. Emerging principles for the development of resistance to antihormonal therapy: Implications for the clinical utility of fulvestrant. J Steroid Biochem Mol Biol. 2006;102:128-38. PubMed
• Lewis-Wambi JS, and Jordan VC. Case Histories: Raloxifene. In: Comprehensive Medicinal Chemistry II, Volume 8 (eds. John Taylor and David Triggle) Elsevier Limited, Oxford, UK. 2006;103-121.
• Lewis-Wambi JS, and Jordan VC. Treatment of post-menopausal breast cancer with selective estrogen receptor modulators (SERMs). Breast Disease. 2005-2006;24:93-105.
• Jordan VC, Lewis JS, Osipo C, Cheng D. The apoptotic action of estrogen following exhaustive antihormonal therapy: a new clinical treatment strategy. Breast. 2005;14:624-30. PubMed
• Lewis JS, Jordan VC. Selective Estrogen Receptor Modulators (SERMs): Mechanism of anticarcinogenesis and drug resistance. Mutat Res. 2005;591:247-63. PubMed
• Lewis JS, Cheng D, and Jordan VC (2004). Targeting Oestrogen to Kill the Cancer but not the Patient. British Journal of Cancer. 2004;90:944-9. PubMed
• Lewis JS, Jordan VC. In: Harris JR, Lippman ME, Morrow M, and Osborne KC, eds. Diseases of the Breast: Chemoprevention of Breast Cancer: Laboratory Principles, 3rd Edition. Philadelphia: Lippincott Williams & Wilkins, 2003:347-362.