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Medical Oncology

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The Medical Oncology department provides quality diagnosis, treatment, and care for patients with cancer.

Traditional chemotherapy and new clinical trials provide our Medical Oncologists with access to a tremendous range of new anticancer treatments, including medicines and combinations of medicines.

George Simon, MD, FACP, FCCP, is the leader of the Fox Chase Thoracic Oncology Program and has a career-long interest in developing personalized therapies for the treatment of patients with various stages of lung cancer. He has pioneered a number of clinical trials testing whether individualized chemotherapy selection for patients with advanced lung cancer will lead to better outcomes. Several of these studies are ongoing and others are in concept development.

"Personalized" treatment involves identifying characteristics of individual patients' tumors in order to determine their responsiveness to specific chemotherapy drugs. The ultimate goal of such analysis is to determine which tumors are sensitive to a given drug and equally important, which tumors are resistant to specific drugs.

In fact, Dr. George Simon is now conducting a clinical trial for Patients with Advanced Non-Small-Cell Lung Cancer. A similar approach has already benefited the Fox Chase Gastrointestinal Cancer program, where patients with metastatic colorectal cancer are routinely screened for mutations in the K-RAS gene to determine the most effective drug treatment. Fox Chase's Clinical Molecular Genetics Laboratory has been conducting this test since 2007.

This focus on personalized medicine is just another example of Fox Chase's leadership in bringing state-of-the-art research directly to the bedside and delivering expert and compassionate care with the goal of improving patient outcomes.

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